Differential Prognosis of True Bifurcation Lesions According to Left Main Versus Non–Left Main Location and Treatment Strategy by Ki Hong Choi, Chang‐Wook Nam, Francesco Bruno, Yun‐Kyeong Cho, Leonardo De Luca, Jeehoon Kang, Alessio Mattesini, Young Bin Song, Alessandra Truffa, Hyo‐Soo Kim, Wojciech Wańha, Woo Jung Chun, Sebastiano Gili, Gerard Helft, Seung Hwan Han, Bernardo Cortese, Cheol Hyun Lee, Javier Escaned, Hyuck‐Jun Yoon, Alaide Chieffo, Joo‐Yong Hahn, Guglielmo Gallone, Seung‐Hyuk Choi, Gaetano De Ferrari, Bon‐Kwon Koo, Giorgio Quadri, Seung‐Ho Hur, Fabrizio D'Ascenzo, Hyeon‐Cheol Gwon, Ovidio de Filippo

“…This study aimed to identify whether clinical outcomes of true bifurcation lesions differed between left main coronary artery (LM) and non‐LM bifurcations and to determine the optimal treatment strategy for subtypes of bifurcation lesions in the current‐generation drug‐eluting stent era. …”
Get full text

Transcriptome Analysis of Effect of Cordyceps militaris Aqueous Extract in Human Gastric Cancer Cell BGC-823 on Different RCD Pathways by Mingqi CUI, Kaiwen YU, Yang SONG, Fangxu XU, Shenghou WANG, Ze WANG

“…Cytological examination revealed typical apoptotic morphological characteristics in gastric cancer cells treated with the XG water extract, with an early apoptotic rate reaching 24.8%, while cell cycle arrest occurred at the G2/M stage. qRT-PCR showed that the expression of BCL2, BCL2L1, CASP3, CASP9, and XIAP was significantly inhibited (P<0.01), whereas that of ENDOG and AIF was significantly upregulated (P<0.01), consistent with the results of transcriptome sequencing. …”
Get full text

Phytochemical analysis and biological activities of solvent extracts and silver nanoparticles obtained from Woodwardia unigemmata (Makino) Nakai. by Syed Ahsan Shah, Alia Gul, Ghulam Mujtaba Shah, Maha Saeed Ibrahim Wizrah, Awais Khalid, Mamoona Munir, Zainab Maqbool, Arusa Aftab, Mazen R Alrahili, Ayesha Siddiqua, M Yasmin Begum

“…The ethanolic extracts (500 μg, 1000 μg, 2000 μg) of the W. unigemmata were found to have cytotoxicity against both gastric cancer (AGS and SGC7901) and normal cell lines (GES-1); a significant cellular proliferation arrest was observed. These results suggest that W. …”
Get full text

Hallazgos de la ecoencefalografía transfontanelar en niños con fontanela anterior abierta y factores de riesgo asociados by Andrés Fabián Gualpa Jácome, Bárbara García Hernández, Diana Elizabeth Belnalcázar Villacreces, Alexis Rodríguez Hernández, Olga Lidia Fernández Chongo, Tahimí Conde Cueto

“…El parto distócico y la hipertensión arterial en la madre, la prematuridad y la enfermedad hipóxico isquémica en el niño, fueron los factores de riesgo más observados. …”
Get full text

Men's more frequent predisposing factors in infectious endocarditis facilitate improvement of outcomes by shortening of diagnostic delay by S. Andreß, K. Reischmann, S. Markovic, F. Rohlmann, B. Hay, W. Rottbauer, D. Buckert, S. d'Almeida

“…Men exhibited a higher prevalence of predisposing cardiac conditions (p = 0.012) due to a higher frequency of a history of implantable cardioverter defibrillator implantation (p = 0.004), and were more likely to have poor dental status (p = 0.001), and coronary artery disease (p = 0.002). The incidence of the complications of heart failure with reduced ejection fraction (p = 0.007) and new-onset dialysis (p = 0.012) were higher, the time in the intensive care unit (p = 0.012) longer. …”
Get full text

LncRNA-ANRIL regulates CDKN2A to promote malignant proliferation of Kasumi-1 cells by Jianxia Xu, Jingxin Zhang, Chengsi Zhang, Huali Hu, Siqi Wang, Fahua Deng, Wu Zhou, Yuancheng Liu, Chenlong Hu, Hai Huang, Sixi Wei

“…Knockdown of ANRIL and CDKN2A led to G1 phase arrest accompanied by reduced CDK2/4/6 and cyclin D1 protein levels, while ANRIL upregulation induced the opposite effect. …”
Get full text

A New CYP2E1 Inhibitor, 12-Imidazolyl-1-dodecanol, Represents a Potential Treatment for Hepatocellular Carcinoma by Torsten Diesinger, Alfred Lautwein, Sebastian Bergler, Dominik Buckert, Christian Renz, Radovan Dvorsky, Vyacheslav Buko, Siarhei Kirko, Edith Schneider, Florian Kuchenbauer, Mukesh Kumar, Cagatay Günes, Felicitas Genze, Berthold Büchele, Thomas Simmet, Martin Haslbeck, Kai Masur, Thomas Barth, Dieter Müller-Enoch, Thomas Wirth, Thomas Haehner

“…Cell-cycle analysis showed a complete loss of proliferating cells with a simultaneous increase in S-phase arrest beginning at a threshold dose of 30 μM. I-ol also reduced xenograft tumour growth in nude mice. …”
Get full text

About the science of pedagogy (how to avoid the transformation of pedagogical science into ideology) by I. P. Smirnov

“…The classical pedagogical foundations evolutionary development inherent in scientific knowledge are deformed by current ideological attitudes, nullifying the constitutional guarantee (Article 44) on freedom of literary, artistic, scientific, technical and other forms of creativity. …”
Get full text

Protez Temizleme Ajanlarının Diş Eti Karakterizasyonunda Kullanılan Farklı Materyallerin Yüzey Pürüzlülüğüne Etkisinin Değerlendirilmesi by Özlem Üstün, Hatice Nalan Bozoğulları

“…. % 1’lik NaOCl PMMA’nın yüzey pürüzlülüğünde istatistiksel olarak anlamlı azalmaya sebep olurken, kompozit materyallerinde artışa sebep olmuştur. Sonuç: % 1’lik NaOCl protez temizleme solüsyonu, PMMA akrilik rezinlerin kimyasal temizliği için önerilebilir ancak kompozit rezinlerle modifiye edilen total protezlerde yüzey pürüzlülüğünü arttırdığı dikkate alınmalıdır. …”
Get full text

Intraoperative Analgesia with Magnesium Sulfate versus Remifentanil Guided by Plethysmographic Stress Index in Post-Bariatric Dermolipectomy: A Randomized Study by S. E. Silva Filho, S. Dainez, M. A. M. C. Gonzalez, F. Angelis, J. E. Vieira, C. S. Sandes

“…There was also no statistical difference in the variation of mean arterial pressure before and after intubation (p = 0.656) and before and after the surgical incision (p = 0.911). …”
Get full text

Dinamik Yükleme Yapılan Kısa İmplantlarda Kron/İmplant Oranının Stres Dağılımına Etkisinin İncelenmesi by Ersan Çelik, A. Nehir Özden

“…Tüm modellerde, kron/implant oranındaki artış implant sistemini oluşturan parçalarda ve kemik dokuda stres seviyelerinde belirgin bir artışa neden olmuştur.Sonuçlar: Bu çalışmanın limitleri dahilinde elde edilen sayısal değerler, kron/implant oranının yük transfer mekanizmalarını ve implantların klinik başarı sürelerini etkilediğini göstermiştir. …”
Get full text

Investigating the Reliability of Shore Hardness in the Design of Procedural Task Trainers by Kyleigh Kriener, Kate Sinclair, Grant Robison, Raushan Lala, Hayley Finley, William Jase Richardson, Mark J. Midwinter

“…Using human tissues (internal carotid artery [ICA], internal jugular vein [IJV], vagus nerve [VN], sternocleidomastoid muscle [SCM], and overlying skin [skin]), this study evaluates (1) the inter-rater reliability of Shore hardness measurements, (2) examines the relationship between tissue thickness and hardness, and (3) investigates the impact of a measurement method (freehand vs. durometer stand). …”
Get full text

High Sensitivity C-Reactive Protein Level in Children with Congenital Heart Disease: A Single Center Study by Faten Abd el-Aziz, Nevian Nabil Abbas, Hala Ashraf, Rehab Mohammed Elkady, Heba H. Zeid

“…The level of Hs-CRP did not correlate with age, birth weight, heart rate, respiratory rate, SpO2, weight percentile, height percentile, hemoglobin level, total leucocytic level, pulmonary artery pressure, ejection fraction (EF), or fractional shortening (FS). …”
Get full text

Sur les intermédia by Dick Higgins

“…Le défi alors se dédouble : pour l’œuvre, la question ne concerne plus sa forme, mais son discours ; pour l'artiste, l'objectif n'est plus l'exploration de sa technique, mais l'usage politique de son art.III. …”
Get full text

Trends and cost structure of drug-based secondary prevention of ischemic strokes by Konstantin Kohlhase, Ferdinand O. Bohmann, Christian Grefkes, Adam Strzelczyk, Laurent M. Willems

“…Etiologies divided into large-artery atherosclerosis (29.9%), cardioembolic (25.6%), cryptogenic (26.8%), and small-vessel disease (17.8%). …”
Get full text

Challenging cases of adherent periarterial vein during subinguinal Fisch technique and subinguinal micro-varicocelecotmy and sclerotherapy: a prospective comparative study by Amr Elahwany, Nashaat Nabil, Sameh Fayek GamalEl Din, Ahmed Raef Sadek, Ahmed Ewais Sayed, Ahmed Ragab

“…Consequently, leaving the artery intact or ligating it together with the adherent vein may pose a challenge. …”
Get full text

Anthropological Dimension of the Philosophical "Literature-Centric" Model of Ukrainian Romanticism by Z. O. Yankovska, L. V. Sorochuk

“…It provided samples of highly artistic works, unique names of talented writers – creators and thinkers, who in their works reflected the philosophy of time. …”
Get full text

Prevalence of pulmonary hypertension and associated factors among rheumatic heart disease patients in Ethiopia by Asmamaw Gedefaw, Yihealem Yabebal Ayele, Gebeyaw Wudie, Abiyot Tefera, Agerye Kassa Yirdaw, Tadele Demilew

“…Results The mean systolic pulmonary arterial pressure (sPAP) of the participants was 50.2 mmHg [SD ± 25.0 mmHg]. …”
Get full text

Ginseng-derived Nanoparticles Inhibit Lung Cancer Cell Growth by Promoting Macrophage M1 Polarization by Liangliang FAN, Limei REN, Song YANG, Wenjing LI, Yueming ZHAO, Ronghua ZHAO, Daqing ZHAO, Jiawen WANG

“…This study will provide a theoretical basis for further research on fresh ginseng medicine. Methods: The CCK-8 assay was employed to detect the effect of GDNPs on the viability of macrophages (RAW264.7). …”
Get full text

Caracterización clínico-epidemiológica de pacientes con un primer evento de fibrilación auricular by Víctor Manuel Regal Cuesta, Lázaro Enrique de la Cruz Avilés, Aymara Marcia Hernández Cardoso, Fransisco de Jesús Valladares Carvajal, Liz María Calvo Díaz, Milagros Lisset León Regal

“…Los antecedentes patológicos personales más frecuentes fueron: la hipertensión arterial (74,1 %), la diabetes mellitus tipo 2 (16,7 %) y las valvulopatías (11,1 %). …”
Get full text