Factors associated with risk of sarcopenia in older adults by Daniel Vicentini de Oliveira, Renan Ferreira de Oliveira, Matheus Amarante do Nascimento, Gabriel Lucas Morais Freire, José Roberto Andrade do Nascimento Júnior, Rogéria Vicentini de Oliveira, Sônia Maria Marques Gomes Bertolini

“…Ao comparar as proporções de doenças relatadas de acordo com o risco de sarcopenia, houve diferença significante entre cardiopatia (p = 0,001), hipertensão arterial sistêmica (p = 0,001), acidente vascular cerebral (p = 0,001), diabetes ( p = 0,049), osteoartrite (p = 0,001), doença pulmonar (p = 0,034), depressão (p = 0,001) e osteoporose (p = 0,001). …”
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Assessment of Groundwater Potential Zones of Upper Blue Nile River Basin Using Multi-Influencing Factors under GIS and RS Environment: A Case Study on Guder Watersheds, Abay Basin,... by Timketa Adula Duguma, Gemechis Adula Duguma

“…The study also revealed that the zone of high groundwater potential has high soil depth, and the zone of low groundwater showed low soil depth as the capacity of the aquifer to store water may depend on the depth of soil profile. This study attests to the GIS and remote sensing techniques as an effective model for delineation of GWPZs and can be applied at other basins of Ethiopia.…”
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Scientific virtual reality as a research tool in prehistoric archaeology: the case of Atxurra Cave (northern Spain) by Antonio Torres, Mª Ángeles Medina-Alcaide, Iñaki Intxaurbe, Olivia Rivero, Joseba Rios-Garaizar, Martin Arriolabengoa, Juan Francisco Ruiz-López, Diego Garate

“…Combining this with new digital technologies, it is now possible to reconstruct Palaeolithic artistic creation and contemplation environments with precision, offering researchers an immersive and interactive experience through virtual reality (VR). …”
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Preparation of Iron Oxide and Titania-Based Composite, Core-Shell Populated, Nanoparticulates Material by Two-Step LASER Ablation in Aqueous Media as Antimicrobial and Anticancer A... by Hasan H. Bahjat, Raid A. Ismail, Ghassan M. Sulaiman, Hamdoon A. Mohammed, Mohsen Al-Omar, Salman A. A. Mohammed, Riaz A. Khan

“…The flow cytometry analyses confirmed the NPs’ cytotoxic impacts against the human lung cancer A549 cell lines through the initiation of apoptosis and promotion of the cell cycle arrest at the G1 phase of cell division. To further confirm the cytotoxic effects and the mechanism of the anticancer activity of the synthesized NPs against the A549 cell lines, several related parameters (cell viability, membrane permeability, nuclear intensity, and cytochrome-C release) were analyzed using the high-content screening (HCS) assay. …”
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PCSK9-antibodies fail to block PCSK9-induced inflammation in macrophages and cannot recapitulate protective effects of PCSK9-deficiency in experimental myocardial infarction by Simon Rauterberg, Simon Rauterberg, Carmen Härdtner, Jennifer Hein, Paola Schrepf, Remi Peyronnet, Christoph Koentges, Tamara A. Vico, Carolin Ehlert, Bianca Dufner, Diana Lindner, Constantin von zur Mühlen, Dennis Wolf, Dirk Westermann, Ingo Hilgendorf, Alexander von Ehr

“…This study investigates the impact of PCSK9 on heart function post-MI and evaluates the effects of PCSK9 inhibition via Alirocumab.MethodsWe used PCSK9 knockout (KO) mice and wildtype (WT) mice and in vivo treatment with Alirocumab to analyze cardiac function and survival post-MI induced by permanent ligation of the left anterior descending artery. PCSK9 and LDL receptor levels were measured using ELISA and qRT-PCR. …”
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Evaluating the effectiveness of handheld ultrasound in primary blast lung injury: a comprehensive study by Shifeng Shao, Zhengbin Wu, Jun Liu, Zhikang Liao, Yuan Yao, Liang Zhang, Yaoli Wang, Hui Zhao

“…Immediate lung ultrasound following the BLUE-PLUS protocol and arterial blood gas analysis were conducted pre-injury and 0.5 h, 3 h, 6 h, 12 h, and 24 h post-injury, respectively. …”
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Early Subclinical Atherosclerosis in Gestational Diabetes: The Predictive Role of Routine Biomarkers and Nutrigenetic Variants by Marica Franzago, Federica Fraticelli, Marta Di Nicola, Francesco Bianco, Daniela Marchetti, Claudio Celentano, Marco Liberati, Raffaele De Caterina, Liborio Stuppia, Ester Vitacolonna

“…All women then attended a 3-year-postpartum follow-up and on that occasion performed an oral glucose tolerance test (OGTT, with 75 g oral glucose), the measurement of carotid artery intima-media thickness (cIMT), and analyses of metabolic parameters. …”
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Methyltransferase-like 7B participates in bladder cancer via ACSL3 m6A modification in a ferroptosis manner by Jiani He, Changming Dong, Xiandong Song, Zhongkai Qiu, Hao Zhang, Yuanjun Jiang, Tao Liu, Xiaojun Man

“…Besides, METTL7B knockdown induced cell cycle arrest in G1 phase with a reduction in cyclin D1(CCND1), CDK4, and CDK6 levels and an elevation in CDKN2D levels in cells. …”
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Reconstruction of Partial Glossectomy Defects in Patients with Squamous Cell Carcinoma of Oral Tongue: A Prospective Clinical Study on the Assessment and Comparison of Intraoperati... by Shubhanshi Kangloo, Nitin Bhola, Anchal Agarwal, Raj Kumar Chakraborty, Priyatam Mishra, Saurabh Pillai

“…Islanded Nasolabial Flap Tunneled Under the Mandible (INFTUM) is a modification of the conventional nasolabial flap based on the facial artery. The flap is raised by dissecting to a certain length to adequately reach a significant distance for reconstruction of the glossectomy defects of mild-to-moderate size. …”
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PET/CT-derived coronary calcium score may predict cardiac complications in anthracycline-treated patients with lymphoma by Genevieve Douglas, Zoe Loh, Evonne S.Y. Shum, Sze-Ting Lee, Niamh Waters, Garry Hamilton, Geoffrey Chong, Alexandra C. Murphy, Eliza A. Hawkes

“…In noncancer populations, coronary artery calcium scoring (CACS) effectively identifies individuals who may benefit from aggressive CVR modification to lower the risk of cardiovascular events. …”
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Clinical characteristics and outcomes in Asian patients with heart failure with mildly reduced ejection fraction by Julian Cheong Kiat Tay, Shaw Yang Chia, Siew Hui Michelle Koh, David Kheng Leng Sim, Ping Chai, Seet Yoong Loh, Fazlur Rehman Jaufeerally, Sheldon Shao Guang Lee, Patrick Zhan Yun Lim, Jonathan Yap

“…HFmrEF patients were more likely to be gender neutral, of mid-range age and have concomitant diabetes mellitus, hyperlipidaemia, peripheral vascular disease and coronary artery disease (P < 0.001). The two-year overall mortality rates for HFrEF, HFmrEF and HFpEF were 32.9%, 31.8% and 29.1%, respectively. …”
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Factors associated with hospital length of stay in patients admitted with suspected malaria in Kenya: secondary analysis of a cross-sectional survey by Hillary Kipruto, Beatrice Machini, Jacqueline Chesang, Beatrice Amboko, Thomas N O Achia

“…Conversely, patients with confirmed severe malaria and those treated with injectable artesunate had a significantly increased cumulative incidence of discharge by 21.4% (SDHR 1.214; 95% CI 1.082 to 1.362) and 33.9% (SDHR 1.339; 95% CI 1.184 to 1.515), respectively.Conclusions Factors of inpatient clinical processes that influence hospital LOS were identified. …”
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Effects of dexmedetomidine combined with intravenous general anesthesia on hemodynamics and inflammatory factors in patients undergoing laparoscopic colorectal cancer surgery by Chunling Liu, Yong Gui, Min Zeng, Zhidong Zhou

“…Heart rate (HR) and mean arterial pressure (MAP) at S1, S2, and S3 in the experimental group were lower, as compared with the control group (P <⁠0.05). …”
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The optimal treatment of invasive ductal and lobular carcinoma occurring at the same time needs to be established by Supriya Peshin, Rafi Iftekher, Rabia Iqbal, Shagun Singh, Moka Nagaishwarya

“…The complexity of this case was further heightened by a significant family history of breast and colon cancers, and comorbid conditions including borderline diabetes, hypertension and coronary artery disease (CAD), which required careful therapeutic consideration to balance efficacy and tolerability. …”
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Different effects of mechano- and metaboreflex on the central blood pressure waveform by Nobuhiro Nakamura, Peng Heng, Naoyuki Hayashi

“…The carotid BP (cBP) waveform was obtained from the right common carotid artery as the central BP waveform. We evaluated the first systolic peak (P1) and second systolic peak (P2) from the cBP waveform.ResultsSPS increased cBP with an increase in P1 (p &lt; 0.05), whereas PEI increased cBP with an increase in P2 (p &lt; 0.05). …”
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Development and validation of a novel risk-predicted model for early sepsis-associated acute kidney injury in critically ill patients: a retrospective cohort study by Bo Li, Kun Zhang, Cong-Cong Zhao, Zi-Han Nan, Yan-Ling Yin, Li-Xia Liu, Zhen-Jie Hu

“…The external validation cohort was generated from a single-centre ICU database from China.Participants A total of 7179 critically ill patients with sepsis were included in the development cohort and 269 patients with sepsis were included in the external validation cohort.Results A total of 12 risk factors (age, weight, atrial fibrillation, chronic coronary syndrome, central venous pressure, urine output, temperature, lactate, pH, difference in alveolar-arterial oxygen pressure, prothrombin time and mechanical ventilation) were included in the final prediction model. …”
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Metabolik Sendromu Olan Hastalarda Visseral Yağlanma Oranı ve Boyun Çevresi Arasındaki İlişki by Altuğ Kut, Hakan Gülmez

“…Obezite ve diyabetin görülme sıklığındaki artışa paralel, her geçen gün daha fazla insanı etkilemekte olan ve multi faktöriyel risk etmenlerinin bir araya gelmesi sonucu oluşan metabolik sendrom, kardiyovasküler hastalık riskini de beraberinde getirdiği için 21. yüzyılın önemli sağlık sorunlarından biridir.Gereç ve Yöntem: Bu araştırmada, kilo yakınması ile başvuran hastalarda, boyun çevresi ölçümlerini bazı metabolik ve antropometrik ölçümlerle karşılaştırmayı ve özellikle metabolik sendromu olan hastalarda, visseral yağlanma oranları ile boyun çevresi ölçümleri arasındaki korelasyonu göstermeyi amaçladık. …”
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Variables perioperatorias que influyen en la morbimortalidad de pacientes operados de fractura de cadera by Joan Laffita Zamora, Carol Dalila González Pedroso, Edwin García García, Miriela Pérez Casanova, Arianne Brown Pérez, Raul Portilla Puente

“…Las complicaciones más frecuentes fueron la anemia (33,3 %) y la hipotensión arterial (16,7 %). Conclusiones: se identificaron como factores pronósticos de muerte: el antecedente de cardiopatía isquémica, anemia preoperatoria, clasificación elevada del estado físico, uso de anestesia general, pérdidas sanguíneas mayores de 500 mL, uso de trasfusiones de glóbulos, estadía mayor de siete días y la aparición de complicaciones postoperatorias. …”
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Right ventricular mechanical pattern in patients undergoing mitral valve surgery: a predictor of post‐operative dysfunction? by Márton Tokodi, Endre Németh, Bálint K. Lakatos, Erika Kispál, Zoltán Tősér, Levente Staub, Kristóf Rácz, Ádám Soltész, Szabolcs Szigeti, Tamás Varga, János Gál, Béla Merkely, Attila Kovács

“…We decomposed the motion of the ventricle to compute longitudinal ejection fraction (LEF) and radial ejection fraction (REF). Pulmonary artery catheterization was performed to monitor RV stroke work index (RVSWi). …”
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Unusual hypertrophic cardiomyopathy: case report of an early onset wild-type ATTR amyloidosis accompanied by a chromosomal duplication involving the MYH6 and MYH7 gene by Jassin Hamidi, Yvonne Hanel, Sven Dittmann, Wanda Maria Gerding, Huu Phuc Nguyen, Karin Klingel, Eric Schulze-Bahr

“…Typical symptoms associated with HCM include atrial fibrillation (AF), syncope, ventricular fibrillation, and cardiac arrest. At the molecular level, various genetic and/or non-genetic etiologies can lead to HCM.Case summaryIn this case, we report on a 60-year-old male patient with severe, progressive hypertrophic cardiomyopathy (HCM) in an uncommon and ambivalent setting. …”
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