Surgical Injury and Ischemia Prime the Adipose Stromal Vascular Fraction and Increase Angiogenic Capacity in a Mouse Limb Ischemia Model by Satoko Kishimoto, Ken-ichi Inoue, Ryoichi Sohma, Shigeru Toyoda, Masashi Sakuma, Teruo Inoue, Ken-ichiro Yoshida

“…Subcutaneous fat from the inguinal region of BALB/c mice was surgically processed (primed) by mincing adipose parenchyma (injury) and ligating the subcutaneous fat-feeding artery (ischemia). SVFs were isolated on day 0, 1, 3, 5, or 7 after the priming procedures. …”
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The direct and urinary electrolyte-mediated effects of ambient temperature on population blood pressure: A causal mediation analysis by Ayesha Mukhopadhyay, Momenul Haque Mondol, Mahbubur Rahman, Leanne Unicomb, Rizwana Khan, Hoimonty Mazumder, Mohammad Nahian Ferdous, Emily V. Pickering, Konstantinos C. Makris, Alberto J. Caban-Martinez, Faruk Ahmed, Mohammad Shamsudduha, Fawaz Mzayek, Chunrong Jia, Hongmei Zhang, Anwar Musah, Lora E. Fleming, Matthew P. Smeltzer, Howard H. Chang, John L. Jefferies, Csaba P. Kovesdy, Xichen Mou, Abu Mohd Naser

“…We detected similar associations for diastolic BP, pulse pressure, and mean arterial pressure. We found a significant inverse direct effect of ambient temperature on BP compared to minimally mediated urine electrolyte effects. …”
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Factores previos asociados a disfunción orgánica múltiple en adultos quemados de gravedad by Elvira María Martínez Barreto, Adrián González León, Roberto Suarez Suri

“…<br /> <strong>Resultados:</strong> al momento del ingreso las variables mayormente asociadas al síndrome, fueron: superficie corporal quemada, profundidad AB y B, frecuencia cardíaca, frecuencia respiratoria, déficit arterial de base, relación PO2FIO2, sodio, potasio y recuento leucocitario. …”
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Risk factors and early prediction of cardiorenal syndrome type 3 among acute kidney injury patients: a cohort study by Hui Lin, Xiaoyu Guo, Mengzhu Wang, Xiaole Su, Xi Qiao

“…Its performance and accuracy were evaluated by the area under the curve (AUC), calibration curve and decision curve analysis, with further validation through a validation cohort.Results The nomogram included 6 risk factors: age (OR = 1.03; 95%CI = 1.009–1.052; p = 0.006), cardiovascular disease (CVD) history (OR = 2.802; 95%CI = 1.193–6.582; p = 0.018), mean artery pressure (MAP) (OR = 1.033; 95%CI = 1.012–1.054; p = 0.002), hemoglobin (OR = 0.973; 95%CI = 0.96-–0.987; p < 0.001), homocysteine (OR = 1.05; 95%CI = 1.03–1.069; p < 0.001), AKI stage [(stage 1: reference), (stage 2: OR = 5.427; 95%CI = 1.781–16.534; p = 0.003), (stage 3: OR = 5.554; 95%CI = 2.234–13.805; p < 0.001)]. …”
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Risk Estimation of Severe Primary Graft Dysfunction in Heart Transplant Recipients Using a Smartphone by Souhila Ait-Tigrine, Roger Hullin, Elsa Hoti, Matthias Kirsch, Piergiorgio Tozzi

“…Background: Currently, there are no standardized guidelines for graft allocation in heart transplants (HTxs), particularly when considering organs from marginal donors and donors after cardiocirculatory arrest. This complexity highlights the need for an effective risk analysis tool for primary graft dysfunction (PGD), a severe complication in HTx. …”
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Intentionally self-injured patients have lower mortality when treated at trauma centers versus non-trauma centers in South Korea by Jin Woo, Han Zo Choi, Jongkyeong Kang

“…However, compared with those treated at non-TCs, patients treated at TCs had a higher rate of surgery or transcatheter arterial embolization (14.2% vs 38.4%; p&lt;0.001) and a higher admission rate to the emergency department (34.4% vs 60.6%; p&lt;0.001). …”
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Longitudinal impact of cross-clamp duration on postoperative sleep disturbance and quality of life in elderly cardiac surgery patients: a secondary analysis of the MINDDS trial by Grace E. Namirembe, Jamie Sparling, Alexis Novak, Ariel Mueller, Julia Bertsch, Kwame Wiredu, Jason Z. Qu, M. Brandon Westover, Timothy T. Houle, Oluwaseun Akeju

“…ObjectivesThis study aimed to assess the enduring impact of cross-clamp duration on postoperative sleep disturbance and functional outcomes (up to 180 days) in cardiac surgery patients.DesignThis is a secondary analysis of data from a randomized, double-blind trial comparing dexmedetomidine to placebo for delirium prevention (Minimizing ICU Neurological Dysfunction with Dexmedetomidine-induced Sleep).SettingData from patients recruited at a tertiary medical center in Boston, Massachusetts, between March 2017 and February 2022 were analyzed in January 2024.ParticipantsThe study included 394 patients aged ≥60 who underwent cardiac surgery with cardiopulmonary bypass.InterventionsThe primary exposure was cross-clamp time, while secondary exposures included surgical type [isolated coronary artery bypass graft (CABG) or not] and dexmedetomidine randomization.Measurements and main resultsThe primary outcome was sleep quality, assessed using the PROMIS Sleep Disturbance questionnaire at 30, 90, and 180 days postoperatively. …”
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Procedural sedative effect of remimazolam in ICU patients on invasive mechanical ventilation: a randomised, prospective study by Youli Tian, Jintong Li, Minggen Jin, YiHua Piao, Jisheng Sheng, Zhixiong Mei, Qingsong Cui, Lilin Li

“…Results Our primary outcome was the mean arterial pressure (MAP), which significantly differed on Days 4 and 7 (P = 0.021, control group vs. experimental group = 85.23 ± 11.24 vs. 94.36 ± 13.18, P = 0.023, 83.55 ± 8.94 vs. 92.66 ± 7.02). …”
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Levosimendan and Global Longitudinal Strain Assessment in Sepsis (GLASSES 1): a study protocol for an observational study by Iacopo Cappellini, Alessandra Melai, Lucia Zamidei, Maddalena Parise, Simone Cipani, Guglielmo Consales

“…Once the infusion cycle of the calcium-sensitising drug has been carried out, the infusion of dobutamine will be reduced until it stops, and the CI, SVI, GLS and arterial elastance (Ea):Ventricular Elastance (Ees) will be re-evaluated. …”
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NCAPD3-mediated ferroptosis of 2,3,5,4’-Tetrahydroxystilbene-2-O-β-D-glucoside inhibits proliferation in T47D cells by Jianfen Shen, Shuo Zhang, Shuo Zhang, Yan Song, Yan Song, Leiming Yang, Leiming Yang, Qi Huang, Qi Huang, Pengyu Wang, Pengyu Wang, Youzhi Zhang, Youzhi Zhang

“…Moreover, THSG could induce cell cycle arrest in G2/M stage and reduce ferroptosis-related protein expression (xCT and GPx4). …”
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The GRACE Scale in the Prognosis of Patients with Takotsubo Syndrome by Malgorzata Zalewska-Adamiec, Lukasz Kuzma, Slawomir Dobrzycki, Hanna Bachorzewska-Gajewska

“…The in-hospital stay of Takotsubo in the patients with higher GRACE scores was associated with higher incidence of pneumonia (36.7% vs 7.69%, p=0.0004), rhythm abnormalities (17.3% vs 3.85%, p=0.026), and serious complications (cardiogenic shock, pulmonary edema, and sudden cardiac arrest) (30.6% vs 5.77%, p=0.001). The mean observation period was 7.2 years. …”
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El agua es de los pueblos y no de Belo Monte: represas y pérdidas de redes de sociabilidad de las poblaciones afectadas representadas en arpilleras amazónicas by Marina Ertzogue, Monise Busquets

“…Esta es una técnica artesanal textil de las mujeres de Isla Negra (Chile), que fue utilizada como instrumento de resistencia durante la dictadura de Pinochet (1973-1990). …”
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Concurrent Renorrhaphy During Renal Mass Excision in Laparoscopic Nephron-Sparing Surgery: A Novel Surgical Technique by Nurullah Hamidi, Tuncel Uzel

“…The renal pedicle was dissected, and the main renal artery was secured with the vessel loop. After opening Gerota’s fascia, the mass was found on the lateral side of lower pole. …”
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Clinical anxiety among a sample of dental students in South Sinai by Christine Raouf George Mikhail, Mai Hamdy Ragab, Yousra Ahmed, Eman D. El Desouky, Fatma E. A. Hassanein, Mohamed Bekhit, Marwa Hassan Mostafa

“…Also, extracting tooth and arresting postoperative bleeding had the same score of 13.7%, while the rest of other clinical situations ranged from 11.8 to 1.1%. …”
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TcPO2 as a Predictor of Limb Salvage or Amputation in Patients of Critical Limb Ischemia by Rahul Merkhed, Vikram Patra, Rishi Dhillon, Rohit Mehra, CVNM Dattatreya, Ramandeep Kaur, Gagandeep Singh Vohra, Surjeet Dwivedi

“…Discussion And Conclusion: This underscores the critical role of TcPO2 in assessing vascular compromise, especially in cases where conventional methods like ankle-brachial pressure index (ABPI) may be unreliable due to arterial calcifications. In our analysis, CKD and TcPO2 < 40 emerged as independent predictors of non-healing ulcers or stump in univariate regression. …”
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The simpler modified fried frailty scale predicts 2-year mortality in older adults with heart failure: a pilot study by Celalettin Küçük, Serdar Özkök, Gülistan Bahat, Ekrem Bilal Karaayvaz, Mustafa Altınkaynak, Alpay Medetalibeyoğlu, Mehmet Akif Karan

“…In a median follow-up of 759 days, cardiomegaly, increased pulmonary artery pressure (PAP) and frailty defined by SMFFS were the only predictors of mortality in older adults with HF after adjustments for age, falls in the previous year, undernutrition, probable sarcopenia, functional impairments, and quality of life [HR (95% CI) were 3.88 (1.05–14.3), 1.05 (1.01–1.09), and 10.96 (1.07–112.05) (p = 0.027); for older age, PAP, and frailty, respectively]. …”
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New Bipolar Electrosurgical Vessel Sealing Device Provides Improved Performance and Procedural Efficiency by Chambers R, Sarno D, Roweton S

“…Rheagan Chambers, Danielle Sarno, Susan Roweton Surgical Research and Development, Surgical Operating Unit, Medtronic, Lafayette, CO, USACorrespondence: Susan Roweton, Email susan.roweton@medtronic.comPurpose: This study compared the performance of the new LigaSure™ XP Maryland Jaw Sealer/Divider (XP Maryland) to that of LigaSure Atlas™ (Atlas) and LigaSure™ Dolphin Tip (Dolphin Tip), two early LigaSure™ (LigaSure) devices characterized by consistent and reliable clinical performance.Methods: Ex vivo bench testing on porcine renal arteries compared burst pressures, seal times, and rates of sticking, incomplete cuts, and charring between XP Maryland and Atlas and between XP Maryland and Dolphin Tip. …”
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Effect of nursing process-based nursing decision implementation on emergency patients with acute ST-segment elevation myocardial infarction by Tiantian Wan, Caixia Wang, Jingli Shi, Shujian Wu

“…Results Through intervention, the IG suggested visibly shorter rescue time, vein opening time, intervention procedure time, and hospital stay compared to the CG; the probability of heart failure (HF), cardiac arrest, and death in the IG was visibly lower than in the CG; the physical health, mental health, social relationships, and environmental scores in the IG were visibly higher than in the CG. …”
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Exploring the perspectives of healthcare workers and Program managers on the use of Truenat as a new tool for TB and DR-TB diagnosis in Nigeria: A qualitative study. by Nkiru Nwokoye, Austin Ihesie, Jamiu Olabamiji, Kingsley Ochei, Rupert Eneogu, Michael Umoren, Femi Odola, Debby Nongo, Aderonke Agbaje, Bethrand Odume, Omosalewa Oyelaran, Wayne van Germert, Lucy Mupfumi, Elom Emeka, Chukwuma Anyaike, Sarah Cook Scalise, Edmund Ndudi Ossai

“…<h4>Results</h4>All the participants attested to the reliability and acceptability of Truenat results, they also highlighted the portability and ease-of-use especially for community outreach testing. …”
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Validating the Hypoglycaemic and Hypotensive Roles of Salvia serotina (Chicken Weed) in Normal Healthy Sprague–Dawley Rats by Tameika Bartley, Paul Reese, Sophie Turfus, Ruby Alexander-Lindo

“…Aqueous, hexane, ethyl acetate, and methanol crude extracts of S. serotina L. were investigated for their anti-oxidant activities and hypoglycaemic and hypotensive effects in normal, healthy Sprague–Dawley rats using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, oral glucose tolerance test (OGTT), and the CODA noninvasive blood pressure system to determine systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), and heart rate (HR). The aqueous extract caused a free radical scavenging effect with an IC50 value of 10.2 ± 1.01 µg/mL versus vitamin C (9.42 ± 1.01 µg/mL). …”
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