Hubungan Kebiasaan Merokok dengan Tekanan Darah pada Siswa SMK N 1 Padang by Aulia Fash Farabi, Afriwardi Afriwardi, Gusti Revilla

“…Sedangkan hasil analisis data statistik kebiasaan merokok dengan mean arterial pressure (MAP) didapatkan p = 0,094, Simpulan penelitian ini menunjukan tidak terdapat hubungan kebiasaan merokok dengan tekanan darah sistolik, tekanan darah diastolik dan MAP.…”
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Inflammatory adhesion mediates myocardial segmental necroptosis induced by mixed lineage kinase domain-like protein in acute myocardial infarction by Lijiang Wei, Naifu Wan, Wentong Zhu, Chenchen Liu, Zeyu Chen, Wuwei Rong, Lujun Zhang, Meifeng Xie, Yueqi Qin, Ting Sun, Qing Jing, Ankang Lyu

“…AMI was induced by coronary artery ligation. The role of MLKL in regulating myocardial morphological necroptosis was evaluated using immunofluorescence staining, flow cytometry, qRT-PCR, Western blot, CCK-8 assay, and ELISA. …”
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Prior Anticoagulation and Risk of Hemorrhagic Transformation in Acute Stroke: A Post Hoc Analysis of the PRODAST Study by Gerrit M. Grosse, Anika Hüsing, Andreas Stang, Nils Kuklik, Marcus Brinkmann, Martin Grond, Jens D. Rollnik, Lars Marquardt, Andrea Kraft, Eckhard Schlemm, Carsten Eggers, Christoph C. Eschenfelder, Christian Weimar, Hans‐Christoph Diener

“…After adjustment for confounders (arterial hypertension, diabetes, heart failure, age, and sex), patients with prior anticoagulation had less severe strokes (−2.5 National Institutes of Health Stroke Scale points [95% CI, −2.8 to −2.2]), smaller infarct sizes (−23 mL [95% CI, −44 mL to −2 mL], n=4041), and reduced odds for hemorrhagic transformation (5% versus 10%; odds ratio, 0.48 [95% CI, 0.40–0.57]) compared with patients without antithrombotic treatment. …”
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Prophylactic Ozone Administration Reduces Intestinal Mucosa Injury Induced by Intestinal Ischemia-Reperfusion in the Rat by Ozkan Onal, Fahri Yetisir, A. Ebru Salman Sarer, N. Dilara Zeybek, C. Oztug Onal, Banu Yurekli, H. Tugrul Celik, Ayse Sirma, Mehmet Kılıc

“…Ischemia Reperfusion (IR) group underwent superior mesenteric artery occlusion for one hour and then reperfusion for two hours. …”
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Investigating the relationship of hydration status on the clinical outcomes of COVID-19 patients by Mahdiye Rezaei, Nader Salari, Amirhossein Naghibzadeh, Mohammad Mohammadi, Alireza Abdi

“…Furthermore, the Pearson correlation test revealed no significant relationship between the Free Water Deficit tool results and levels of sodium, potassium, urea, creatinine, blood osmolality, total and direct bilirubin, blood lactate, PaO2, FiO2, platelet counts, mean arterial pressure and patient weight. Conclusion The findings of this study did not support the initial research objectives and hypotheses, as no significant relationship was found between hydration status and clinical outcomes in COVID-19 patients. …”
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Systemic Lupus Erythematosus, Its Impact on Selected Cardiovascular Risk Factors, and Correlation with Duration of Illness: A Pilot Study by Brygida Przywara-Chowaniec, Dominika Blachut, Jan Harpula, Marcin Bereś, Agnieszka Nowak, Ewa Nowalany-Kozielska

“…Thickness of the IMT was higher and statistically important among patients with SLE, both in left (1.22 ± 0.27 mm vs. 0.7 ± 0.21 mm, p=0.0001) and right common carotid artery (1.16 ± 0.26 mm vs. 0.59 ± 0.15 mm, p=0.0001), compared to the controls. …”
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Long-term outcomes of Fontan palliation; the influence of the dominant ventricle by Abdelmonem M. Helal, Jameel Al-Ata, Nashwa Mostafa Badawy, Ahmed Abdelwahed, Wejdan Khaled Ba-Atiyah, Anhar Ali Baeshen, Abdullah J. Alata, Ahmed F. Elmahrouk, Mohammad S. Shihata, Ahmed A. Jamjoom, Samia Bekheet

“…Factors influencing long-term mortality were older age, right dominance, and elevated pulmonary artery pressure. Conclusions Patients with left dominance exhibited superior survival rates and fewer complications compared to those with right dominance and codominance. …”
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Gestational diabetes mellitus and offspring’s carotid intima–media thickness at birth: MySweetHeart Cohort study by Umberto Simeoni, Antje Horsch, Arnaud Chiolero, Yvan Vial, Nicole Sekarski, Jardena J Puder, Pascal Bovet, Stefano Di Bernardo, Yvan Mivelaz, Adina Mihaela Epure, Sandrine Estoppey Younes, Bobby Stuijfzand, Leah Gilbert, Stefano Lanzi, Justine Gross, Stefano Di Bernardo, Dan Quansah, Jean-Benoît Rossel, Amar Arhab, Sandrine Estoppey Younes, Seyda Mayerat

“…A longer-term follow-up that includes additional vascular measures, such as endothelial function or arterial stiffness, may shed further light on the cardiovascular health trajectories in children born to mothers with GDM.Trial registration number NCT02872974; Pre-results.…”
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Effect of Nebivolol and Olmesartan on 24-Hour Brachial and Aortic Blood Pressure in the Acute Stage of Ischemic Stroke by Eleni Georgianou, Panagiotis I. Georgianos, Konstantinos Petidis, Konstantinos Markakis, Ioanna Zografou, Asterios Karagiannis

“…This study suggests that during the acute phase of ischemic stroke, nebivolol is equally effective with olmesartan in improving 24-hour aortic pressure and arterial stiffness indices. ClinicalTrials.gov identifier number: NCT03655964.…”
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Understanding the impact of racism on surgical outcomes in settler nation-states USA and Canada: a protocol for a systematic review and meta-analysis by Mary Brindle, Oluwatomilayo Daodu, Tyara Marchand, Saffa Aziz, Ifeoluwa Adedipe, Mirna Matta

“…The procedures of interest will be the four most common (hip arthroplasty, knee arthroplasty, appendectomy and cholecystectomy), and the five highest risk (oesophagectomy, abdominal aortic aneurysm, aortic valve replacement, coronary artery bypass graft and pancreatectomy) surgical procedures performed in these countries. …”
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Correlation between OSAHS and Early Peripheral Atherosclerosis Indices in Patients with Type 2 Diabetes Mellitus in China: A Cross-Sectional Inpatient Study by Xin Zhao, Xiaofeng Yu, Sixu Xin, Wei Zhang, Xiaomei Zhang, Linong Ji

“…Results. (1) As the degree of OSAHS increased, ABI decreased gradually and was lower than that in the control group, but PWV increased and was higher than that in the control group (p<0.05, respectively). (2) The apnea-hypopnea index (AHI) positively correlated with PWV (r=0.36, p<0.05) and negatively correlated with ABI (r=−0.37, p<0.05). (3) Multivariate logistic regression showed that after adjusting for age, gender, duration, BMI, blood pressure, blood glucose, blood lipid, and other factors, OSAHS was a risk factor of lower extremity arterial disease (LEAD) in patients with T2DM. With the increase of degree of OSAHS, the risk of lower extremity atherosclerosis gradually increased. …”
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Are patients with stage III non-small cell lung cancer treated with chemoradiotherapy at risk for cardiac events? Results from a retrospective cohort study by Juliette Degens, D De Ruysscher, Ruud Houben, Bastiaan Kietselaer, Gerben Bootsma, Lizza Hendriks, Ellen Huijbers, Annemie Schols, Anne-Marie C Dingemans

“…The most common cardiac events were arrhythmia (14.6%), heart failure (7.6%) and symptomatic coronary artery disease (6.8%). Pre-existent cardiac comorbidity (HR 1.96; p&lt;0.01) and WHO-performance score ≥2 (HR 2.71; p&lt;0.01) were significantly associated with developing a cardiac event. …”
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Autoregulatory Feedback Mechanism of P38MAPK/Caspase-8 in Photodynamic Therapy-Hydrophilic/Lipophilic Tetra-α-(4-carboxyphenoxy) Phthalocyanine Zinc-Induced Apoptosis of Human Hepa... by Yu Wang, Chunhui Xia, Wei Chen, Yuhang Chen, Yiyi Wang, Tao Li

“…Our previous study showed that hydrophilic/lipophilic tetra-α-(4-carboxyphenoxy) phthalocyanine zinc- (TαPcZn-) mediated PDT (TαPcZn-PDT) inhibits the proliferation of human hepatocellular carcinoma Bel-7402 cells by triggering apoptosis and arresting cell cycle. However, mechanisms of TαPcZn-PDT-induced apoptosis of Bel-7402 cells have not been fully clarified. …”
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Synergistic Antitumor Effects of Anlotinib Combined with Oral 5-Fluorouracil/S-1 via Inhibiting Src/AKT Signaling Pathway in Small-Cell Lung Cancer by Xinhang Xia, Wenhu Pi, Yanli Lan, Xiaomai Wu, Dongqing Lv, Yinnan Meng, Haihua Yang, Wei Wang

“…And apoptosis, cell cycle arrest, and cell motility rates were stronger when anlotinib combined with 5-FU than in the anlotinib or 5-FU alone. …”
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Identification of crucial pathways and genes linked to endoplasmic reticulum stress in PCOS through combined bioinformatic analysis by Yan Zhang, Xiujuan Chen, Yuan Lin, Xiaoqing Liu, Xiumei Xiong

“…Our study revealed that these DEGs were primarily associated with cell cycle arrest, p53-mediated signal transduction, drug response, and gland development, with molecular functions enriched in growth factor binding, collagen binding, and receptor protein kinase activity. …”
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Comparison of Hemodynamic Response following Spinal Anesthesia between Controlled Hypertensive and Normotensive Patients Undergoing Surgery below the Umbilicus: An Observational Pr... by Leake Gebrargs, Bereket Gebremeskel, Bacha Aberra, Assefa Hika, Yusuf Yimer, Misrak Weldeyohannes, Suleiman Jemal, Degena Behrey, Abere Tilahun

“…There was a statistically significant difference in the mean systolic blood pressure, mean arterial pressure, mean heart rate, and vasopressor consumption at the measurement time interval between controlled hypertension and normotensive groups. …”
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Association between Circulating B-Type Natriuretic Peptide and Diabetic Peripheral Neuropathy: A Cross-Sectional Study of a Chinese Type 2 Diabetic Population by Pijun Yan, Qin Wan, Zhihong Zhang, Yong Xu, Ying Miao, Pan Chen, Chenlin Gao

“…Circulating levels of BNP were significantly and positively associated with systolic blood pressure (P=0.035), neutrophil-to-lymphocyte ratio (P=0.007), creatinine (P=0.030), vibration perception threshold values (P=0.021), and the prevalence of diabetic foot ulceration (P=0.039), peripheral arterial disease (P=0.013), DPN (P=0.032), and diabetic nephropathy (P=0.020) and negatively with lymphocyte count (P=0.003) and ankle-brachial index (P=0.038), irrespective of age, sex, and body mass index. …”
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Prevalence and predictors of infected diabetic foot ulcers (DFU) and DFU-related osteomyelitis amongst industrial workers wearing occupational safety footwear by Sunetra Mondal, Moushumi Lodh, Sambit Sahoo, Kaushik Paul, Debasis Biswas, Chaitanya Krishna, Ashok Parida, Arunangshu Ganguly, Riddhi DasGupta

“…Those with osteomyelitis in the OF group ( n = 53) were younger (53.3 vs. 57, p = 0.02), had higher prevalence of peripheral arterial disease (41.5% vs. 24.1%), past-amputation (28.3% vs. 11.1%), higher SINBAD scores, and were also less likely to change occupational-footwear at < = 6-month-interval (22.6% vs. 55.6%) than those without osteomyelitis (p < 0.05 for all). …”
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Prenatal genetic detection in foetus with gallbladder size anomalies: cohort study and systematic review of the literature by Yimo Zeng, Rong Hu, Jian Lu, Yiming Qi, Dan Chen, Chaoxiang Yang, Jing Wu

“…Non-isolated GB size anomalies were associated with findings such as hyperechogenic bowel, ventriculomegaly, foetal growth restriction (FGR), cardiac anomalies, renal dysplasia and single umbilical artery. The overall diagnostic yield of genetic tests was 10.57% (24/227). …”
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Constitutive activation of the Src-family kinases Fgr and Hck enhances the tumor burden of acute myeloid leukemia cells in immunocompromised mice by Sherry T. Shu, Li Chen, Giancarlo Gonzalez-Areizaga, Thomas E. Smithgall

“…Both CC-Hck and CC-Fgr cell populations became sensitized to growth arrest by Src-family kinase inhibitors previously shown to suppress the growth of bone marrow cells from AML patients in vitro and decrease AML cell engraftment in immunocompromised mice. …”
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