Rad3 decorates critical chromosomal domains with gammaH2A to protect genome integrity during S-Phase in fission yeast. by Sophie Rozenzhak, Eva Mejía-Ramírez, Jessica S Williams, Lana Schaffer, Jennifer A Hammond, Steven R Head, Paul Russell

“…Schizosaccharomyces pombe Rad3 checkpoint kinase and its human ortholog ATR are essential for maintaining genome integrity in cells treated with genotoxins that damage DNA or arrest replication forks. Rad3 and ATR also function during unperturbed growth, although the events triggering their activation and their critical functions are largely unknown. …”
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The Utility of Point of Care Test for Soluble ST2 in Predicting Adverse Cardiac Events during Acute Care of ST-Segment Elevation Myocardial Infarction by Anggoro Budi Hartopo, Indah Sukmasari, Ira Puspitawati

“…We analyzed 95 subjects with STEMI and 10 patients with stable coronary artery disease as controls. The median sST2 level was significantly higher in subjects with STEMI as compared to controls (152.1 ng/mL versus 28.5 ng/mL, p<0.01). …”
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Survival trends of extracorporeal membrane oxygenation support for pediatric emergency patients in regional and metropolitan areas in Japan by Noriyuki Kaku, Wakato Matsuoka, Kentaro Ide, Takaaki Totoki, Katsuki Hirai, Soichi Mizuguchi, Kanako Higashi, Kenichi Tetsuhara, Hazumu Nagata, Satoshi Nakagawa, Yasuyuki Kakihana, Akira Shiose, Shouichi Ohga

“…In regional centers, deterioration of Pediatric Cerebral Performance Category (PCPC) scores were more frequent (65.7% vs. 49.4%; p = 0.042), but survival rates and ΔPCPC scores (PCPC at ICU discharge–PCPC before admission) improved in the second half of the study period (p = 0.005 and p = 0.046, respectively). Veno-arterial ECMO (odds ratio [OR], 3.00; p < 0.03), extracorporeal cardiopulmonary resuscitation (OR, 8.98; p < 0.01), and absence of myocarditis (OR, 5.47; p < 0.01) were independent risk factors for deterioration of the PCPC score. …”
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Citrus Fruit Farmers’ Adaptation Capacities to Climate Variability in Ngora District, Eastern Uganda. by Achuu, Simon Peter, Nachuha, Sarah, Nakizito, Joweria, Musoke, Semakula Henry, Opedes, Hosea Enos

“…Findings indicated that 82% of the respondents attested that rainfall amounts and temperature patterns had changed with the highest rainfall of 1686 mm received in 1991, and the lowest amount of 785mm received in 2009. …”
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Angiogenesis Regulated by Electroacupuncture Combined with Rehabilitation Training in Cerebral Ischemia Involved in PI3K/Akt Signaling Pathway by Wenchao YAO, Mengxing LI, Qing LIU, Mingyue TONG, Peng HE, Wei TANG

“…The right middle cerebral artery occlusion (MCAO) model was established by using Zea longa external carotid artery thread occlusion method. …”
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Correlation Between Learning and Memory Impairment and Changes in Cerebral White Matter Nerve Fibers and Pericytes in Rats with Chronic Cerebral Ischemia by HUANG Jia, WANG Mengxue, NI Jinglei, LIANG Shengxiang, LIN Bingbing

“…The sham operation group were treated with bilateral common carotid arteries separation without ligation, and chronic cerebral ischemia models were established by ligation of bilateral common carotid arteries in the 28 days after operation group and the 56 days after operation group. …”
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Molecular Epidemiological Characteristics of blaIMP-4-Carrying Klebsiella pneumoniae ST-11 in Hospitalized Patients by Xue YE, Zhang D, Du S, Chen D, Liu S, Peng T, Li C, Zhang J, Wang X

“…Nosocomial infections, antibiotic exposure, and urinary and venous/arterial catheterization within 3 months were the risk factors for developing CRKP infection.Keywords: Klebsiella pneumoniae, carbapenemase, multi-locus sequence typing, MLST, ST-11, IMP-4…”
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Long-term effects of maternal exposure to surgical stress at the earliest stage of pregnancy on blood pressure and behavior in offspring of OXYS rats by I. N. Rozhkova, T. N. Igonina, D. S. Ragaeva, O. M.  Petrova, E. Yu. Brusentsev, V. A. Naprimerov, S. Ya. Amstislavsky

“…Body weight (BW), systolic (SAP) and diastolic (DAP) arterial pressure as well as behavior in open field (OF) and elevated plus maze (EPM) tests were studied in the offspring of females exposed to surgical treatment during pregnancy (OXYS­PS) at the age of 3 mo. …”
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Prompt Conditioned Batik Pattern Generation Using LoRA Weighted Diffusion Model With Classifier-Free Guidance by Rahmatulloh Daffa Izzuddin Wahid, Novanto Yudistira, Candra Dewi, Irawati Nurmala Sari, Dyanningrum Pradhikta, Fatmawati

“…This research contributes to the field of computer-assisted batik pattern generation, providing significant advantages for batik artists, manufacturers, and users by accelerating the pattern creation process and expanding the possibilities of batik art.…”
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Meta-Analysis of Diagnostic Performance of Contrast-Fractional Flow Reserve versus Quantitative Flow Ratio for Functional Assessment of Coronary Stenoses by Ruitao Zhang, Jianwei Zhang, Lijun Guo

“…Both cFFR and QFR have good diagnostic performance in detecting functional severity of coronary arteries and showed similar diagnostic parameters.…”
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Association of Autoantibodies against M2-Muscarinic Acetylcholine Receptor with Atrial Fibrosis in Atrial Fibrillation Patients by Guiling Ma, Xuejiao Wu, Lijun Zeng, Jiawei Jin, Xingpeng Liu, Jianjun Zhang, Lin Zhang

“…Twenty-six patients with sinus rhythm, scheduled to undergo coronary artery bypass grafting surgery, were enrolled into the non-AF group. …”
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Adrenal Disorders and the Paediatric Brain: Pathophysiological Considerations and Clinical Implications by Vincenzo Salpietro, Agata Polizzi, Gabriella Di Rosa, Anna Claudia Romeo, Valeria Dipasquale, Paolo Morabito, Valeria Chirico, Teresa Arrigo, Martino Ruggieri

“…Idiopathic intracranial hypertension (IIH), a disorder of unclear pathophysiology characterised by increased cerebrospinal fluid (CSF) pressure, has been described in children with hypercortisolism, adrenal insufficiency, and hyperaldosteronism, reflecting the potential underlying involvement of the adrenal-brain axis in the regulation of CSF pressure homeostasis. Arterial hypertension caused by paediatric adenomas or tumours of the adrenal cortex or medulla has been associated with various hypertension-related neurological manifestations. …”
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Screen interpretation of Franz Kafka's novel 'The Trial': Interaction of the author with the s­cript writer and film director by K.V. Arjantzeva

“…Harold Pinter is a British writer, playwright, poet and screenwriter, and the recipient of the Nobel Prize in Literature in 2005, whose artistic genius is familiar to the Russian reading audience. …”
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Innovative Application of Nano-Organic Photochromic New Materials in Hakka Traditional Decorative Pattern Design by HuiJuan Lai

“…At the same time, it is also the essence of artists accumulated through life in the past dynasties, which has a certain impact on the integration of modern art design and traditional culture. …”
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Distribution of Pupil Size and Associated Factors: Results from the Population-Based Gutenberg Health Study by Marian Kiel, Stephanie D. Grabitz, Susanne Hopf, Thomas Koeck, Philipp S. Wild, Irene Schmidtmann, Karl J. Lackner, Thomas Münzel, Manfred E. Beutel, Norbert Pfeiffer, Alexander K. Schuster

“…A smaller pupil was associated with older age, hyperopic refractive error, previous cataract surgery, diabetes, obesity, and ACE inhibitor intake, whereas wider pupil was associated with female gender, arterial hypertension, intake of tricyclic antidepressants, and intake of SNRI and tetracyclic antidepressants. …”
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Reduced retinal microvascular density in women with coronary microvascular dysfunction: A pilot study by Sakshi Shiromani, Ahmed AlBadri, Aaron Lindeke-Myers, Arielle Schwartz, Nishant Vatsa, Esha Dave, Fauzia Rashid, Nieraj Jain, Puja K. Mehta

“…Objective: To compare retinal microvascular density among women with ischemia with no obstructive coronary artery disease (INOCA) with and without coronary microvascular dysfunction (CMD). …”
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Crack growth threshold under hold time conditions in DA Inconel 718 – A transition in the crack growth mechanism by E. Fessler, S. Pierret, E. Andrieu, V. Bonnand

“…K regime and slip bands have also been observed at the tip of an arrested crack at low ?K. Transgranular fracture and slip bands are usually observed under pure fatigue loading conditions. …”
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Enhancing Perioperative Outcomes of Pancreatic Surgery with Wearable Augmented Reality Assistance System: A Matched-Pair Analysis by Hamraz Javaheri, MSc, Omid Ghamarnejad, MD, Rizky Widyaningsih, MD, Ragnar Bade, PhD, Paul Lukowicz, PhD, Jakob Karolus, PhD, Gregor Alexander Stavrou, MD

“…Additionally, more patients in the ARAS group required arterial resection compared with the control group (15.0% vs 0.0%, P = 0.002). …”
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Low-Dose Aspirin as Primary Prophylaxis for Cardiovascular Events in Rheumatoid Arthritis: An Italian Multicentre Retrospective Study by Daniela Iacono, Serena Fasano, Ilenia Pantano, Virginia D’Abrosca, Piero Ruscitti, Domenico Paolo Emanuele Margiotta, Luca Navarini, Nicola Maruotti, Rosa Daniela Grembiale, Francesco Paolo Cantatore, Antonella Afeltra, Roberto Giacomelli, Gabriele Valentini

“…At multivariable analysis, arterial hypertension (HR 9.3) and hypercholesterolemia (HR 2.8) resulted to be positive predictors and ASA (HR 0.09) and hydroxychloroquine (HCQ) (HR 0.22) to be negative predictors. …”
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Protocol for project recovery after cardiac surgery: a single-center cohort study leveraging digital platform to characterise longitudinal patient-reported postoperative recovery p... by Harlan M Krumholz, Erica Spatz, Sanket S Dhruva, Yawei Zhang, Makoto Mori, Cornell Brooks, Bobak J Mortazavi, George C Linderman, Lawrence A Grab, Arnar Geirsson, Sarwat I Chaudhry

“…We are using a health-information exchange platform to collect patient-reported outcome measures (PROMs) and wearable device data to phenotype recovery patterns in the 30-day period after cardiac surgery hospital discharge, to identify factors associated with these phenotypes and to investigate phenotype associations with clinical outcomes.Methods and analysis We designed a prospective cohort study to enrol 200 patients undergoing valve, coronary artery bypass graft or aortic surgery at a tertiary centre in the USA. …”
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