The Kidney Transplant Evaluation Process in the Elderly: Reasons for Being Turned down and Opportunities to Improve Cost-Effectiveness in a Single Center by Beatrice P. Concepcion, Rachel C. Forbes, Aihua Bian, Heidi M. Schaefer

“…Results. 345 patients were included in the statistical analysis. 31.6% of patients were turned down: 44% due to coronary artery disease (CAD), peripheral vascular disease (PVD), or both. …”
Get full text

Microvascular angina in postmenopausal women. by Alexander Valdés Martín, Sherien Sixto Fernández

“…Endothelial function was measured in the brachial artery by ultrasound, and a 24 hours (Holter) lectrocardiographic study. …”
Get full text

Mesenchymal stem cells-derived exosomes attenuate mouse non-heart-beating liver transplantation through Mir-17-5p-regulated Kupffer cell pyroptosis by Yang Tian, Ming Jin, Nanwei Ye, Zhenzhen Gao, Yuancong Jiang, Sheng Yan

“…Methods In this study, an arterialized mouse non-heart-beating (NHB) liver transplantation model was used to investigate the effect of MSCs-Exo on NHB liver transplantation. …”
Get full text

Ginger polysaccharide UGP1 suppressed human colon cancer growth via p53, Bax/Bcl-2, caspase-3 pathways and immunomodulation by Yanfang Qian, Chenying Shi, Chen Cheng, Dengwei Liao, Junping Liu, Gui-tang Chen

“…The results demonstrated that UGP1 could induce S-phase cell cycle arrest, up-regulate the expression of Bax and p53, down-regulate the expression of Bcl-2, and activate the downstream protein caspase-9 and caspase-3, which was related to intrinsic apoptosis pathway on HCT116 cells. …”
Get full text

Metabolomic and transcriptomic analyses revealed potential mechanisms of Anchusa italica Retz. in alleviating cerebral ischemia–reperfusion injury via Wnt/β-catenin pathway modulat... by Wenta Tan, Shuo Fu, Yufei Wang, Bojun Hu, Guiquan Ding, Li Zhang, Wen Zhang, Guanhua Du, Junke Song

“…The model was established using the filament occlusion method, which involved blocking the middle cerebral artery for 1.5 h and then removing the filament to restore blood flow. …”
Get full text

Comportamiento de defectos refractivos en estudiantes y trabajadores hipertensos y/o diabéticos. Universidad de Ciencias Médicas de Cienfuegos by Dainisett Molina Curbelo, Lisandra Sánchez Peñalver, Vismary Valdés Vales, Xiomara Vasallo García

“…<br /><strong>Métodos:</strong> estudio descriptivo realizado entre enero de 2017 e igual mes del 2018, que incluyó a los 64 pacientes que presentaron antecedentes patológicos personales de hipertensión arterial y/o diabetes mellitus, en los cuales se determinó la presencia o no de defectos refractivos. …”
Get full text

Adverse Effects of Carbetocin versus Oxytocin in the Prevention of Postpartum Haemorrhage after Caesarean Section: A Randomized Controlled Trial by D. Mannaerts, L. Van der Veeken, H. Coppejans, Y. Jacquemyn

“…To compare the incidence of nausea, vomiting, and arterial hypotension between carbetocin and oxytocin to prevent haemorrhage after caesarean section (CS). …”
Get full text

miRNA Expression Profile and Effect of Wenxin Granule in Rats with Ligation-Induced Myocardial Infarction by Aiming Wu, Lixia Lou, Jianying Zhai, Dongmei Zhang, Limin Chai, Bo Nie, Haiyan Zhu, Yonghong Gao, Hongcai Shang, Mingjing Zhao

“…MI rat model was established by a coronary artery ligation surgery. miRNA expression microarrays were performed and the data were deposited in Gene Expression Omnibus (GEO number GSE95855). …”
Get full text

Massive pulmonary thromboembolism in a pediatric patient with eosinophilic granulomatosis with polyangiitis: a case-based review emphasizing management by Batuhan Küçükali, Merve Yazol, Çisem Yıldız, Büşra Acun, Nuran Belder, Nihal Karaçayır, Merve Kutlar, Pelin Esmeray Şenol, Zühre Kaya, Deniz Gezgin Yıldırım, Sevcan A. Bakkaloğlu

“…Abstract Background Pediatric patients with Eosinophilic Granulomatosis with Polyangiitis (EGPA) are at an increased risk of arterial and venous thromboembolism (AVTE). Although the exact mechanisms underlying AVTE remain unclear, eosinophils play a pivotal role in AVTE. …”
Get full text

Upper Gastrointestinal Bleeding as a Debut Form of Groove Pancreatitis: A Diagnostic Challenge by Belén Matías-García, Camilo José Castellón-Pavón, Gustavo Díaz-García, Belén Manso-Abajo, Daniel Hernández-Aceituno, Antonio Hermosín-Peña, Luis Mejías-Sosa, Manuel Durán-Poveda

“…The patient presented melena, arterial hypotension, and 4.4 g/dl of hemoglobin. An upper gastrointestinal endoscopy showed a neoformative ulcerated lesion at the duodenal bulb without active bleeding. …”
Get full text

Case report: Short-course hypofractionated radiation therapy combined with immune checkpoint inhibitors for the treatment of advanced ovarian mucinous cystadenocarcinoma by Xinan Wan, Mingxing Fang, Le Yuan, Hang Zhang, Dan Wang

“…The radiotherapy target area was the metastatic lymph nodes in the right posterior part of the hepatic artery, with a radiation dose of 30 Gy/10 F. Camrelizumab, an immune checkpoint inhibitor, was administered intravenously every three weeks at a dose of 200 mg each time. …”
Get full text

Second-generation BRAF inhibitor Encorafenib resistance is regulated by NCOA4-mediated iron trafficking in the drug-resistant malignant melanoma cells by Ceyda Colakoglu Bergel, Isil Ezgi Eryilmaz, Gulsah Cecener, Unal Egeli

“…The viability, apoptosis, and G0/G1 arrest reflected the acquired chemoresistance. Autophagic Beclin and LC3 proteins, and AKT signaling increased in the A375-R. …”
Get full text

p53-loss induced prostatic epithelial cell plasticity and invasion is driven by a crosstalk with the tumor microenvironment by Darya Yanushko, Beatriz German Falcon, Rana El Bizri, Despoina Pervizou, Robin Dolgos, Céline Keime, Tao Ye, Christelle Thibault-Carpentier, Clementine Le Magnen, Sandrine Henri, Gilles Laverny, Daniel Metzger

“…Using genetically engineered mice, we show that Trp53 deficiency in Pten-null prostatic epithelial cells (PECs) does not impact early cell proliferation and neoplasia formation, nor growth arrest and senescence entry at a later time. However, Trp53-deficiency enhances invasive adenocarcinoma development and promotes metastatic cell dissemination. …”
Get full text

Case Series: Successful Resuscitation of Severe Facial Injuries Caused by a Chainsaw by Han Joo Choi

“…The crushing wound, mandible open fracture, deep laceration of tongue, lip, neck and arterial bleeding were noted around his mandible. Nasotracheal intubation was performed under the bronchoscope-guided. …”
Get full text

Comparing the effects of intrathecal and intra-articular magnesium sulfate and fentanyl on pain after knee arthroscopy; double-blind clinical trial by Houriye Safaripoor, Hesameddin Modir, Alireza Susanabadi, Seyed Yosef Shahtaheri, Mohsen Parsi Khamene

“…Results: No significant difference was found among the groups respecting participants’ arterial oxygen saturation, heart rate, blood pressure, and KA duration (P > 0.05). …”
Get full text

Molecular Imaging of Cathepsin B Proteolytic Enzyme Activity Reflects the Inflammatory Component of Atherosclerotic Pathology and Can Quantitatively Demonstrate the Antiatheroscler... by Dong-Eog Kim, Jeong-Yeon Kim, Dawid Schellingerhout, Soo-Min Shon, Sang-Wuk Jeong, Eo-Jin Kim, Woo Kyung Kim

“…The CatB-related signal, observed in the aortas but not in the cerebral arteries, correlated very well with protease activity and the presence of macrophages on histology. …”
Get full text

Nouvelles dédicaces d’Alésia à Apollon Moritasgus by Olivier de Cazanove, Monique Dondin-Payre

“…A last inscription, known since 1909 (Espérandieu’s excavations of a secondary spring catchment), on a metallescent ceramic handle, makes it possible to increase this small series of similar objects, well attested in spring sanctuaries. One can therefore suggest that the three paterae bearing dedications, from the sanctuary of Apollo Moritasgus, had an identical practical and ritual use, before being gathered together with the other offerings exposed in the sanctuary.…”
Get full text

Red Blood Cell Transfusions and Iron Therapy for Patients Presenting with Acute Upper Gastrointestinal Bleeding: A Survey of Canadian Gastroenterologists and Hepatologists by Kyle J. Fortinsky, Myriam Martel, Roshan Razik, Gillian Spiegle, Zane R. Gallinger, Samir C. Grover, Katerina Pavenski, Adam V. Weizman, Lukasz Kwapisz, Sangeeta Mehta, Sarah Gray, Alan N. Barkun

“…Patients with coronary artery disease (mean Hgb of 84.0 g/L versus 71.0 g/L; p<0.01) or cirrhosis (mean Hgb of 74.4 g/L versus 71.0 g/L; p<0.01) were transfused more liberally than healthy patients. …”
Get full text

RETRACTED: Palmitic Acid Impedes Extravillous Trophoblast Activity by Increasing MRP1 Expression and Function by Yunali Ashar, Qiuxu Teng, John N. D. Wurpel, Zhe-Sheng Chen, Sandra E. Reznik

“…Proliferation and invasion of spiral arteries by EVTs depends upon adequate levels of folate. …”
Get full text

Agricola und das Verkehrte. Zum Umgang mit satztechnischen Idiosynkrasien in Musik des späten 15. Jahrhunderts by Markus Roth

“…. // This essay, starting with the Kyrie I of the Missa Sine Nomine, is dedicated to some remarkable compositional idiosyncracies of Alexander Agricola (1446–1506), of whom his contemporaries attested the talent of “turning things in an unexpected manner” (Hulrich Brätel 1536). …”
Get full text