Cardiovascular Protective Effect of Garcinia dulcis Flower Acetone Extract in 2-Kidney-1-Clip Hypertensive Rats by Nattaya Thongsepee, Pongsakorn Martviset, Wanwisa Himakhun, Pathanin Chantree, Phornphan Sornchuer, Kant Sangpairoj, Siriphun Hiranyachattada

“…Subsequently, the invasive measurement of arterial BP and the heart rate were determined in all anesthetized rats. …”
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An Effect of Ursodeoxycholic Acid on Inflammation, Steatosis and Liver Fibrosis and Atherogenesis Factors in Patients with Non-Alcoholic Fatty Liver Disease: Results of the USPEH S... by M. V. Mayevskaya, M. Yu. Nadinskaia, V. D. Lunkov, I. Yu. Pirogova, E. V. Chesnokov, Kh. B. Kodzoeva, V. T. Ivashkin

“…Before and after the study, liver function and lipid metabolism, liver steatosis index FLI, intimamedia thickness (IMT) of the carotid arteries were determined. The cardiovascular risk was calculated according to the ASCVD 2013.Results. …”
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Evaluation of Shared Space to Reduce Traffic Congestion by Colin Frosch, David Martinelli, Avinash Unnikrishnan

“…A major pedestrian crossing location on West Virginia University’s Downtown campus along a major urban arterial was chosen as the case location upon which the model was to be built. …”
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Percutaneous vacuum-assisted tumor thrombectomy using angiovac and penumbra lightning 12 aspiration systems by Murtaza Jafri, BSc, Brittany Stojak, MD, Owen Mooney, MD, Andrew Macdiarmid, MD, Ian W. Gibson, MD, Surinder Dhaliwal, MD

“…A repeat computer tomography scan revealed extensive thrombus burden with tumor thrombus involving the inferior vena cava, a large right atrial intracardiac thrombus, multiple segmental right pulmonary emboli, and a large embolus causing total occlusion of the left main pulmonary artery with findings suggestive of associated lung infarction. …”
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El Hierro (Canaries) : une île et le choix des transitions énergétique et écologique by Alain Gioda

“…However and first of all, this success of an idea like "Small is beautiful" has been developed by individual initiatives since 1947, supported by artists and the regional political party. The ecological transition was formalized in 2000 with the recognition of “Biosphere Reserve of El Hierro” by the UNESCO declaration. …”
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Treatment selection factors and outcome comparison in acute myocardial infarction by Elham Gholamian, Nasrin Hanifi, Parvin Shiri Ghidari

“…Background: The reopening of occluded arteries in myocardial infarction can be achieved through invasive and non-invasive methods. …”
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Investigation of PACAP Fragments and Related Peptides in Chronic Retinal Hypoperfusion by Dora Werling, Dora Reglodi, Peter Kiss, Gabor Toth, Krisztina Szabadfi, Andrea Tamas, Zsolt Biro, Tamas Atlasz

“…Retinal ischemia can be effectively modelled by permanent bilateral common carotid artery occlusion (BCCAO), which causes chronic hypoperfusion-induced degeneration in the entire rat retina. …”
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Cannabidiol attenuates lipid metabolism and induces CB1 receptor-mediated ER stress associated apoptosis in ovarian cancer cells by Xuanhe Fu, Zhixiong Yu, Fang Fang, Weiping Zhou, Yuxin Bai, Zhongjia Jiang, Biao Yang, Ye Sun, Xing Tian, Guangyan Liu

“…Conversely, by supplementation with unsaturated fatty acid or blocking CB1R, ER stress or reactive oxygen species (ROS) signals with specific inhibitors could significantly relieve CBD induced, dose-dependent, ER stress associated apoptosis, G0-G1 phase arrest, and mitochondrial dysfunction. Taken collectively, these data indicate that CBD may disrupt lipid metabolism, and lead to ER stress-related apoptosis in OCs. …”
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Treating Metabolic Dysregulation and Senescence by Caloric Restriction: Killing Two Birds with One Stone? by Lara Russo, Serena Babboni, Maria Grazia Andreassi, Jalil Daher, Paola Canale, Serena Del Turco, Giuseppina Basta

“…Cellular senescence is a state of permanent cell cycle arrest accompanied by metabolic activity and characteristic phenotypic changes. …”
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Biblioteka mojego wieku – czyli jaka? by Artur Jazdon

“…The new functions will include performing new cultural, educational, social, artistic and communal tasks carried out with a co-operation with other libraries, scientific, educational and cultural instructions. …”
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Nε-carboxyethyl-lysin influences atherosclerotic plaque stability through ZKSCAN3 acetylation-regulated macrophage autophagy via the RAGE/LKB1/AMPK1/SIRT1 pathway by Zhongwei Liu, Jing Liu, Xiqiang Wang, Yong Zhang, Yanpeng Ma, Gongchang Guan, Ya Yuwen, Ni He, Hanxiu Liu, Xingfeng Yu, Sen Ma, Junkui Wang, Jin Zhang, Ling Zhu, Yulian Zhang

“…In this study, we investigated the correlation between acute coronary syndrome (ACS) and serum levels of Nε-carboxyethyl-lysin (CEL), a prominent advanced glycation end product (AGE) elevated in T2DM, in a cohort of 225 patients with coronary artery disease. Using a murine model of atherosclerosis complicated by T2DM, we examined the effects of CEL on plaque stability and macrophage autophagy. …”
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Synergistic Effect of HAD-B1 and Osimertinib Against Gefitinib Resistant HCC827 Non-Small Cell Lung Cancer Cells by Eun-Ju Ko KMD, PhD, Eun-Bin Kwag PhD, Ji-Hye Park KMD, PhD, Sung-Hyuk Cho MS, So-Jung Park KMD, PhD, Mi-Kyung Jung KMD, PhD, In-Cheol Kang PhD, Hwa-Seung Yoo KMD, PhD

“…We found that the synergistic effect of osimertinib and HAD-B1 combination therapy resulted in cancer cell death and cell cycle arrest by targeting the ERK and mTOR signaling pathways. …”
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Cyrus the Great: The Persian king in the context of world history by E.A. Tchiglintsev, E.V. Rung

“…Meanwhile, there is no Oriental, including Old-Persian, evidence attesting of the perception of Cyrus by his subjects or his self-representation. …”
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Epidemiological and clinical variables’ behavior in patients with stroke of Villa Clara by Bettsy Bell Bosch Rodriguez, Arlet López Quintanilla, Mercedes Bordón Hernández, Marbelys Guevara Rodríguez, Eldis Daniel Rodríguez León, Amalia Inés Luna Capote

“…In 67.3% the cardioembolic cause was demonstrated. Arterial hypertension was the main associated risk factor (83.6%). …”
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Prenatal visualization of the fetal uterus in routine 2D ultrasound examination by Pedro Azumendi, Marisa Borenstein, Jesús Salvador Jiménez, Ernesto González-Mesa, Carlos Corrales, Guillermo Azumendi, Ignacio Alonso-Usabiaga, Juan Gómez-Salgado, Francisco Javier Fernández-Carrasco

“…The same plane of the bladder used in the assessment of the umbilical arteries was used. In this transverse view of the fetal pelvis different structures can be identified from front to back: the bladder, the bowel and the vertebral body. …”
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Prognostic Relevance and Function of MSX2 in Colorectal Cancer by Jiancheng Liu, Huaying An, Wei Yuan, Qiang Feng, Lianzhen Chen, Jie Ma

“…In vitro experiments demonstrated that knockdown of MSX2 expression attenuated cell proliferation and invasion, promoted cell cycle arrest and apoptosis, and inactivated Akt phosphorylation. …”
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A realistic human head phantom for electromagnetic detection of brain diseases by Zelin Bai, Diyou Chen, Ke Ma, Gui Jin, Jinlong Qiu, Quanquan Li, Haocheng Li, Mingsheng Chen

“…This article combines high-precision computed tomography (CT) images and magnetic resonance imaging (MRI) images to establish an electromagnetic numerical model of the human head with a real anatomical structure. (1) It had Asian characteristics and encompassed 14 different structures, including skin, muscles, cranial bones, cerebrospinal fluid, cerebral veins, cerebral arteries, gray matter, white matter of the brain, basal ganglia, thalamus, cerebellum, brainstem, eyeballs, and vertebrae. (2) The model used a combination of 0.625 mm-resolution CT and 1 mm-resolution MRI image data for reconstruction, with a smooth surface and high accuracy. (3) Within the simulation environment, this model enabled the generation of various brain disease scenarios, such as different types and degrees of cerebral hemorrhage and cerebral ischemia. …”
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A heteropolysaccharide from Rhodiola rosea L.: preparation, purification and anti-tumor activities in H22-bearing mice by Yaru Wu, Qing Wang, Huiping Liu, Lulu Niu, Mengyu Li, Qi Jia

“…In addition, according to cell cycle, AV-FITC/PI and JC-1, RLP could induce dose-dependent apoptosis of H22 cells via S phase arrested which was through a mitochondrial related pathway. …”
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A Reduction in ADAM17 Expression Is Involved in the Protective Effect of the PPAR-α Activator Fenofibrate on Pressure Overload-Induced Cardiac Hypertrophy by Si-Yu Zeng, Hui-Qin Lu, Qiu-Jiang Yan, Jian Zou

“…This study aimed to determine whether ADAM17 is involved in the protective action of fenofibrate against cardiac hypertrophy. Abdominal artery constriction- (AAC-) induced hypertensive rats were used to observe the effects of fenofibrate on cardiac hypertrophy and ADAM17 expression. …”
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Current Practice of Heart Donor Evaluation in Germany: Multivariable Risk Factor Analysis Confirms Practicability of Guidelines by Sylke Ruth Zeissig, Carl-Ludwig Fischer-Froehlich, Frank Polster, Nils R. Fruehauf, Guenter Kirste, Irene Schmidtmann

“…Successful procurement was determined by low donor age (OR 0.87 per year; 95% CI [0.85–0.89], P<0.0001), large donor height (OR 1.04 per cm; 95% CI [1.02–1.06], P<0.0001), exclusion of impaired left ventricular function or wall motion (OR 0.01; 95% CI [0.002–0.036], P<0.0001), arrhythmia (OR 0.05; 95% CI [0.009–0.260], P=0.0004), and of severe coronary artery disease (OR 0.003; 95% CI [<0.001–0.01], P<0.0001). …”
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