Application of antisense oligonucleotide drugs in amyotrophic lateral sclerosis and Huntington’s disease by Kaili Ou, Qingqing Jia, Dandan Li, Shihua Li, Xiao-Jiang Li, Peng Yin

“…To date, antisense oligonucleotide (ASO) drugs targeting the pathological genes associated with ALS and HD have shown promising results in numerous animal studies and several clinical trials. This review provides a comprehensive overview of the development, mechanisms of action, limitations, and clinical applications of ASO drugs in neurodegenerative diseases, with a specific focus on ALS and HD therapeutic strategies.…”
Get full text

The biodiversity survey of the Cape (BioSCape), integrating remote sensing with biodiversity science by Anabelle W. Cardoso, Erin L. Hestir, Jasper A. Slingsby, Cherie J. Forbes, Glenn R. Moncrieff, Woody Turner, Andrew L. Skowno, Jacob Nesslage, Philip G. Brodrick, Keith D. Gaddis, Adam M. Wilson

“…In situ biodiversity observations of plant and animal communities, estuaries, kelp, and plankton were made using traditional field methods as well as novel approaches like environmental DNA and acoustic surveys. …”
Get full text

A SYSTEMATIC REVIEW OF THE USE OF TULATHROMYCIN IN VETERINARY MEDICINE by Carmen (Pop) Moldovan, Alexandra Dreancă, Oana Rotar, Mihai Madru, Ioan Marcus

“…The study's findings can help animal health professionals explore alternative treatments for respiratory diseases in sheep and improve their overall health. …”
Get full text

Revolutionizing cardiovascular research: Human organoids as a Beacon of hope for understanding and treating cardiovascular diseases by Jinli Li, Yang Li, Guangtao Song, Haiying Wang, Qing Zhang, Min Wang, Muxue Zhao, Bei Wang, HuiGuo Zhu, Liu Ranzhi, Qiang Wang, Yuyan Xiong

“…This groundbreaking technology offers a unique opportunity to study human diseases and address the limitations of traditional animal models. Cardiovascular diseases (CVDs), a leading cause of mortality worldwide, have spurred an increasing number of researchers to explore the great potential of human cardiovascular organoids for cardiovascular research. …”
Get full text

The mitochondria as a potential therapeutic target in cerebral I/R injury by Susu Fang, Susu Fang, Wenzhou Huang, Wenzhou Huang, Xinhui Qu, Xinhui Qu, Wen Chai

“…Among patients with ischemic stroke, the primary treatment goal is to reduce acute cerebral ischemic injury and limit the infarct size in a timely manner by ensuring effective cerebral reperfusion through the administration of either intravenous thrombolysis or endovascular therapy. …”
Get full text

Microscopic Analysis of Temperature Effects on Surface Colonization and Biofilm Morphology of <i>Salmonella enterica</i> by Zachariah Vice, You Zhou, Sapna Chitlapilly Dass, Rong Wang

Get full text

Annual cycle variations in the gut microbiota of migratory black-necked cranes by Yujia Zhang, Ruifeng Ma, Suolangduoerji, Shujuan Ma, Shujuan Ma, Akebota Nuertai, Ke He, Hongyi Liu, Ying Zhu

Get full text

Therapeutic effectiveness of three commercial anthelmintics against strongylids in buffalo calves (Bubalus bubalis) by David Uzcátegui, Víctor Gutiérrez, María Rodríguez, Andrea González, Alfredo Sánchez

“…The study was conducted in a buffalo system dedicated to milk and meat production with crossbreed animals (Murrah and Mediterranean breeds) in the South of Lake Maracaibo, Venezuela. …”
Get full text

Biodiversité, restauration écologique et intensification écologique : quelles imbrications ? by Daouda Ngom

“…The fragmentation of natural ecosystems such as forests has a definite impact on the relationship between man and wild animals, leading to the proliferation of zoonoses. …”
Get full text

The Nine-banded Armadillo (Dasypus novemcinctus) by Joseph M. Schaefer, Mark E. Hostetler

“… Armadillos are prehistoric-looking animals that belong to a family of mammals found primarily in Central and South America. …”
Get full text

The Nine-banded Armadillo (Dasypus novemcinctus) by Joseph M. Schaefer, Mark E. Hostetler

“… Armadillos are prehistoric-looking animals that belong to a family of mammals found primarily in Central and South America. …”
Get full text

Methyl Gallate Attenuates Doxorubicin-Induced Cardiotoxicity in Rats by Suppressing Oxidative Stress by Akheruz Zaman Ahmed, Shakta Mani Satyam, Prakashchandra Shetty, Melanie Rose D’Souza

“…Group III and group IV animals were prophylactically treated with methyl gallate 150 mg/kg/day and 300 mg/kg/day orally, respectively, for seven days. …”
Get full text

Water Hyacinth, an Invasive Species in Africa: A Literature Review by Lubembe, Sharon Indasi, Okoth, Sharon, Turyasingura, Benson, Oyugi, Timothy, Ibarasa, Hillary, Moenga, Kelvin, Chavula, Petros, Tumushabe, Jennifer Turyatemba

“…Tourism and navigation are also affected by limiting access to recreational areas, especially for boat cruising. …”
Get full text

Enhancing Beef Hamburger Quality: A Comprehensive Review of Quality Parameters, Preservatives, and Nanoencapsulation Technologies of Essential and Edible Oils by Tainara Santos Oliveira, Rogeria Comastri de Castro Almeida, Vanessa de Lima Silva, Cláudio Vaz Di Mambro Ribeiro, Leilson Rocha Bezerra, Camila Duarte Ferreira Ribeiro

Get full text

Development of lateral flow immunochromatographic assay with Anti-Pythium insidiosum antibodies for point-of-care testing of vascular pythiosis by Panwad Tongchai, Ati Burassakarn, Nattapong Langsiri, Navaporn Worasilchai, Ariya Chindamporn

“…Abstract The pathogenic oomycete Pythium insidiosum causes a fatal infectious illness known as pythiosis, impacting humans and certain animals in numerous countries in the tropics and subtropics. …”
Get full text

Soft Robotics: Biological Inspiration, State of the Art, and Future Research by Deepak Trivedi, Christopher D. Rahn, William M. Kier, Ian D. Walker

“…Traditional robots have rigid underlying structures that limit their ability to interact with their environment. …”
Get full text

Wireless Modular Implantable Neural Device with One‐touch Magnetic Assembly for Versatile Neuromodulation by Inho Kang, John Bilbily, Choong Yeon Kim, Chuanqian Shi, Manish K. Madasu, Eun Young Jeong, Kyle E. Parker, Do A Kwon, Bum‐Joon Jung, Jae‐Soon Yang, Juhyun Lee, Noah D.L. Kabbaj, Wonhee Lee, Jun‐Bo Yoon, Ream Al‐Hasani, Jianliang Xiao, Jordan G. McCall, Jae‐Woong Jeong

“…However, introducing multiple functionalities into a compact form factor for freely behaving animals presents substantial design hurdles that complicate the device or require more than one device. …”
Get full text

Comparative Effects of Verapamil, Nicardipine, and Nitroglycerin on Myocardial Ischemia/Reperfusion Injury by Hitoshi Yui, Uno Imaizumi, Hisashi Beppu, Mitsuhiro Ito, Munetaka Furuya, Hirofumi Arisaka, Kazu-Ichi Yoshida

“…The aim of this experiment was to establish whether verapamil, nicardipine, and nitroglycerin have (1) infarct size-limiting effects and (2) antiarrhythmic effects in in vivo rabbit hearts during ischemia/reperfusion. …”
Get full text

Synergistic enhancement of spinal fusion in preclinical models using low-dose rhBMP-2 and stromal vascular fraction in an injectable hydrogel composite by Hye Yeong Lee, Seong Bae An, Sae Yeon Hwang, Gwang Yong Hwang, Hye-Lan Lee, Hyun Jung Park, Joongkyum Shin, Keung Nyun Kim, Sung Won Wee, Sol Lip Yoon, Yoon Ha

“…Spinal fusion surgery remains a significant challenge due to limitations in current bone graft materials, particularly in terms of bioactivity, integration, and safety. …”
Get full text

The investigation of aflatoxin, ochratoxin a and zearalenone residues in feeds and feedstuffs by chromatographic method by H. Ahmet ACET, Ömer DEMET, Bünyamin TRAŞ

“…., 12 and 6,6 microgram/kg respectively. The detectalble limits were 1 microgram/kig for aflatoxin, 2 microgram/kg for ochratoxin A and 4 microgram,/kg for zearalenone.…”
Get full text