Therapeutic Potential of Clove Oil in Mitigating Cadmium-Induced Hepatorenal Toxicity Through Antioxidant, Anti-Inflammatory, and Antiapoptotic Mechanisms by Inas M. Elgharib, Fatma M. Abdelhamid, Gehad E. Elshopakey, Hatem Sembawa, Talat A. Albukhari, Waheed A. Filimban, Rehab M. Bagadood, Mohamed E. El-Boshy, Engy F. Risha

“…Future studies should focus on elucidating the precise molecular mechanisms, optimal dosing strategies, and potential synergistic effects of CLO with other therapeutic agents.…”
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Preparation of oat galactolipid and anti-liver cancer effects of oat galactolipid–modified curcumin-loaded liver targeting vesicle by Huiying Ren, Nuo Chen, Yanqing Liu, Meimei Wu, Meimei Wu, Meimei Wu, Jingsong Yan, Jingsong Yan, Jingsong Yan, Mingxiang Chang, Mingxiang Chang, Mingxiang Chang, Hanmin Li, Hanmin Li, Hanmin Li

“…IntroductionThe mortality rate for liver cancer is extremely high but clinical treatments have not made much progress, so it is necessary to develop anticancer agents with lower toxicities and more effective liver-targeting drug delivery systems (LTDDSs). …”
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L’INCLUSIONE NELLA SCUOLA ITALIANA: DALLA FORMAZIONE DEGLI INSEGNANTI ALLA COSTRUZIONE DI UN AMBIENTE DI APPRENDIMENTO INCLUSIVO. IL CASO DELL’INSEGNAMENTO DELLE LINGUE by Mariagrazia Palumbo

“…Questa ricerca ha lo scopo di studiare alcune questioni legate all’inclusione, elemento caratterizzante il mondo dell’istruzione italiano da più di mezzo secolo. …”
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Pharmacological interventions for the management of anesthesia and sedation in patients with Duchenne muscular dystrophy: a systematic review and meta-analysis by Xianghong Lian, Xianghong Lian, Xianghong Lian, Yang Jing, Yang Jing, Yang Jing, Ting Luo, Ting Luo, Ting Luo, Yixin Guo, Yixin Guo, Yixin Guo, Yunzhu Lin, Yunzhu Lin, Yunzhu Lin

“…Compared with those of the control group, the sensitivity of patients with DMD to neuromuscular blocking agents (NMBAs) may have resulted in a prolonged onset time [MD = −0.96, 95% CI (0.71, 2.60), I2 = 33%, P < 0.0001] and recovery time [MD = 2.22, 95% CI (1.14, 3.30), I2 = 76%, P < 0.0001] from anesthesia. …”
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“Space to see the future”? A political economy analysis of child and adolescent mental health and well-being in Ethiopia including routes for change by Kibur Engdawork, Kibur Engdawork, Kibur Engdawork, Lucia D’Ambruoso, Lucia D’Ambruoso, Lucia D’Ambruoso, Lucia D’Ambruoso, Lucia D’Ambruoso, Lucia D’Ambruoso, Tsion Hailu, Tsion Hailu, Tsion Hailu, Mahlet Yared, Mahlet Yared, Girma M. Geletu, Girma M. Geletu, Semere G. Baraki, Semere G. Baraki, Elias Sebsibe, Pamela Abbott

“…We examined structural, institutional, and agentic factors affecting child and adolescent mental well-being in Ethiopia. …”
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Antifungal activity and mechanism of Phoebe bournei wood essential oil against two dermatophytes by Yan Yang, Qinglin Sun, Yuting Zhang, Junhua Huang, Wenjun Ma, Qi Yang, Zaikang Tong, Junhong Zhang

“…These results suggest that PWEO can be used as natural antifungal agents for sustainable applications.…”
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Optimization of the Antibacterial Activity of a Three-Component Essential Oil Mixture from Moroccan <i>Thymus satureioides</i>, <i>Lavandula angustifolia</i>, and <i>Origanum major... by Amine Elbouzidi, Mohamed Taibi, Naoufal El Hachlafi, Mounir Haddou, Mohamed Jeddi, Abdellah Baraich, Saad Bougrine, Ramzi A. Mothana, Mohammed F. Hawwal, Waleed A. Alobaid, Abdeslam Asehraou, Bouchra El Guerrouj, Hanae Naceiri Mrabti, Francois Mesnard, Mohamed Addi

“…Conclusions: The study successfully demonstrates that optimized mixtures of EOs can serve as effective natural antibacterial agents. The findings highlight a novel approach to enhance the applications of essential oils, suggesting their potential use in food preservation and biopharmaceutical formulations. …”
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Efficacy and safety of Janus kinase inhibitors in the treatment of psoriasis and psoriatic arthritis: An analysis of evidence from 2014 to 2022 by Jiao Wang, Tian Ma, Xiaoying Sun, Liu Liu, Seokgyeong Hong, Huijung Cha, Miao Zhang, Jiale Chen, Naixuan Lin, Bin Li, Xin Li

“…Background: The efficacy and safety of Janus kinase (JAK) inhibitors as novel therapeutic agents for psoriasis (PSO) and psoriatic arthritis (PsA) have not yet been systematically evaluated. …”
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Sharing of cmeRABC alleles between C. coli and C. jejuni associated with extensive drug resistance in Campylobacter isolates from infants and poultry in the Peruvian Amazon by Kerry K. Cooper, Evangelos Mourkas, Francesca Schiaffino, Craig T. Parker, Tackeshy N. Pinedo Vasquez, Paul F. Garcia Bardales, Pablo Peñataro Yori, Maribel Paredes Olortegui, Katia Manzanares Villanueva, Lucero Romaina Cachique, Hermann Silva Delgado, Matthew D. Hitchings, Steven Huynh, Samuel K. Sheppard, Ben Pascoe, Margaret N. Kosek

“…Resistance to fluoroquinolones and macrolides is particularly concerning as this compromises the two most effective oral antibiotic agents currently available for human campylobacteriosis. …”
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A retrospective multicenter study on the efficacy and safety of disitamab vedotin monotherapy versus combination with anti-PD-1 immunotherapy in advanced gastric cancer by Shuailei Dong, Chen Wei, Xueting Wang, Xinyi Yang, Wei Shen, Shuyi Li, Jiye Xu, Yijie Ma, Liangyu Bie, Wenyue Yu, Ning Li

“…Abstract Novel therapeutic agents including disitamab vedotin (RC48, an antibody-drug conjugate) and immune-checkpoint inhibitors (e.g., PD-1 inhibitors) have provided new hope as an advanced gastric-cancer (GC) treatment. …”
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Une gestion plurielle des illégalismes : négociations et contradictions dans la régulation des eaux usées au Maroc by Pierre-Louis Mayaux, Naïma Fezza, Zhour Bouzidi

“…It does so by studying the use of untreated, and therefore highly contaminated, wastewater for small-scale market gardening in the heart of the city of Meknes.The management of these illicit water uses primarily involves local agents of the Ministry of the Interior (the moqqadems) as well as their hierarchy (qaïds, General Directorate of Local Authorities in Rabat). …”
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Biologic Therapy and Cardiometabolic Risk in Psoriasis: A Retrospective Review by Annika Smith, Aidin Karahasan, Deborah Yi, Sanjay Yapabandara, James Elhindi, Pablo Fernandez-Penas, Clara Chow, Sarah Zaman

“…The mean PASI at baseline (for BN + BE) was 13.4 (SD 9.8). The biologic agents used, according to frequency, included risankizumab, with 14 participants (35.9%), secukinumab by 7 (17.9%), ustekinumab by 6 (15.4%), ixekizumab by 6 (15.4%), guselkumab by 3 (7.7%), infliximab by 2 (5.1%), and adalimumab by 1 (2.6%). …”
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Reducing Greenhouse Gas Emissions and Modifying Nitrous Oxide Delivery at Stanford: Observational, Pilot Intervention Study by Eric P Kraybill, David Chen, Saadat Khan, Praveen Kalra

“… BackgroundInhalational anesthetic agents are a major source of potent greenhouse gases in the medical sector, and reducing their emissions is a readily addressable goal. …”
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Détermination du statut du Chimpanzé, Pan troglodytes verus, dans une zone non protégée de savane boisée à Bagnomba, Sénégal : Implication pour sa conservation by Papa Ibnou Ndiaye, Landing Badji, Stacy Marie Lindshield, Cheikh Tidiane Bâ, Jill Pruetz

“…Les particularités écologiques des habitats du chimpanzé dans cette zone (relief, végétation, disponibilité d’aliments, entre autres) associées à leur caractère sacré par les populations locales constituent des atouts qui favoriseraient la conservation des chimpanzés dans cette zone si des mesures idoines de protection étaient prises. …”
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Description of Sanitation Clinic Implementation in Primary Health Care Services in Bukittinggi by Vini Jamarin, Rosfita Rasyid, Selfi Renita Rusjdi

“…</p><p><strong>Kata kunci:</strong> klinik sanitasi, puskesmas</p><p> </p><p><strong><em>Abstract</em></strong></p><p><em>Poor sanitation could be the transmission media for environment-based diseases’ agents. The program of Primary Health Care Service (PHCS) which deals with environment-based disease is sanitation clinic. …”
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Clinical Features, Endoscopic Findings, and Predictive Factors for Mortality in Tissue-Invasive Gastrointestinal Cytomegalovirus Disease between Immunocompetent and Immunocompromis... by Panu Wetwittayakhlang, Natthapat Rujeerapaiboon, Poowadon Wetwittayakhlung, Pimsiri Sripongpun, Nannapat Pruphetkaew, Sawangpong Jandee, Naichaya Chamroonkul, Teerha Piratvisuth

“…Patients with HIV infection, malignancy, or receiving immunosuppressive agents (chemotherapy, high dose, or long-term corticosteroids) were defined as the immunocompromised group. …”
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Target Groups for a Short Dexamethasone Course among Critically Ill COVID-19 Patients by Armen Oganesyan, Ruslan Menzulin, Yury Surovoy, Andrei Nikiforchin, Kirill Zykov

“…Corticosteroids are one of the most promising therapeutic agents for critically ill patients with coronavirus disease 2019 (COVID-19). …”
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Multiomic characterization, immunological and prognostic potential of SMAD3 in pan-cancer and validation in LIHC by Tao Zhou, Dan Dan Zhang, Jiejing jin, Jinyang Xie, Jianhua Yu, Chao Zhu, Rong Wan

“…Finally, in our comprehensive analysis of drug sensitivity, we discerned a catalog of prospective therapeutic agents. In our comprehensive analysis across multiple cancer types, we observed a significant disparity in SMAD3 expression compared to normal tissues, and this findings suggest that SMAD3 holds promise as both a prognostic biomarker and a therapeutic target against various cancers. …”
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The influence of exogenous recombinant HSP 70 on the alteration of membrane stiffness in hippocampal neurons following the modeling of neonatal hypoxic-ischemic injury in mice Auth... by Vladimir M. Pokrovsky, Alexey V. Deikin, T Zhang, Nikolai A. Verlov, Andrey L. Konevega, Mikhail V. Korokin

“…., rhHSP70), influence the mechanical properties of membranes, which may be critically important for the development of new therapeutic agents.…”
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Long-term effects of linear versus macrocyclic GBCAs on gene expression in the central nervous system of mice by Chuanbing Wang, Yuxia Tang, Jiajia Tang, Jie Zhang, Siqi Wang, Feiyun Wu, Shouju Wang

“…Abstract Background We examined chronic gadolinium retention impact on gene expression in the mouse central nervous system (CNS) after injection of linear or macrocyclic gadolinium-based contrast agents (GBCAs). Methods From 05/2022 to 07/2023, 36 female mice underwent weekly intraperitoneal injections of gadodiamide (2.5 mmol/kg, linear), gadobutrol (2.5 mmol/kg, macrocyclic), or saline. …”
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