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41441
Bacteria-Inspired Synthesis of Silver-Doped Zinc Oxide Nanocomposites: A Novel Synergistic Approach in Controlling Biofilm and Quorum-Sensing-Regulated Virulence Factors in <i>Pseu...
Published 2025-01-01“…This study underscores the potential of Ag-ZnO NCs as promising agents for combating quorum sensing-mediated virulence in chronic infections caused by multidrug-resistant <i>P</i>. …”
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41442
Effectiveness and safety of oral vancomycin for the treatment of inflammatory bowel disease associated with primary sclerosing cholangitis: a systematic review and pooled analysis
Published 2025-01-01“…Three studies ( n = 11) reported no episodes of acute cholangitis while on OVT. Five studies ( n = 69) reported an incidence rate of 8.7% of vancomycin-resistant enterococci post-OVT to treat IBD-PSC. …”
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41443
«Se nos salió de las manos…». Memorias de empresarios sobre el conflicto armado en el Valle del Cauca
Published 2016-01-01“…Se evidencia también una racionalidad que superpone lo económico a los procesos sociales y políticos, y un debilitamiento de lo político (de los políticos) como agente(s) mediador(es) entre los procesos regionales y nacionales, favoreciendo el uso de vías directas para tramitar y resolver los conflictos locales. …”
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41444
The efficacy and safety of indobufen in patients with ischemic cardiovascular or cerebrovascular diseases: systematic review and meta-analysis
Published 2025-01-01“…Regarding safety, indobufen showed superior clinical outcomes compared to other antiplatelet agents regarding bleeding events, gastrointestinal adverse reactions, and overall adverse reactions, with these differences being more pronounced in cardiovascular diseases. …”
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41445
Activities of Some Medicinal Plants on the Proliferation and Invasion of Brain Tumor Cell Lines
Published 2020-01-01“…It was concluded that these medicinal plants have antiproliferative and anti-invasive activities and possess good prospects as source of anticancer agents especially S. longepedunculata which induced apoptosis in U87 cell line.…”
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41446
The Endocannabinoid, Anandamide, Acts as a Novel Inhibitor of LPS-Induced Inflammasome Activation in Human Gastric Cancer AGS Cell Line: Involvement of CB1 and TRPV1 Receptors
Published 2021-01-01“…Endocannabinoids, such as anandamide (AEA), are emerging as new anticancer therapeutic agents; however, their effects on inflammasome components and underlying mechanisms have not been well elucidated. …”
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41447
Update on Pulmonary Toxicity Induced by New Breast Cancer Treatments
Published 2025-01-01“…Data provided here show that pulmonary toxicity is a quite frequent side effect and underline that early recognition and prompt treatment are crucial for the best outcome of patients, whose overall prognosis is being improved by the availability of these new anticancer agents.Keywords: breast cancer, lung toxicity, Pulmonary toxicity, interstitial lung disease, pneumonia, trastuzumab deruxtecan, CDK4/6i…”
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41448
Prediction of Pt, Ir, Ru, and Rh complexes light absorption in the therapeutic window for phototherapy using machine learning
Published 2025-01-01“…Scientific Contribution: The proposed machine learning (ML) approach predicts the ability of transition metal-based complexes to absorb light in the UV–vis therapeutic window, a key trait for phototherapeutic agents. While ML models have been used to predict UV–vis properties of organic molecules, applying this to metal complexes is novel. …”
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41449
CALIDAD MICROBIOLÓGICA DE PROPÓLEO CRUDO Y SÓLIDOS SOLUBLES DE EXTRACTOS DE PROPÓLEOS DE Apis mellifera EN COLOMBIA
Published 2012-01-01“…Para la norma más exigente, que corresponde a la brasileña, se hallaron porcentajes de cumplimiento del 53,4 y 56,1% para ee P 70 y 96%, respectivamente, y para la norma de Japón se encontraron aceptables 75,9 y 69,7% de los ee P 70 y 96%, respectivamente. …”
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41450
Genetic insights into therapeutic targets for gout: evidence from a multi-omics mendelian randomization study
Published 2024-12-01“…Conclusion This study identified several biomarkers associated with gout risk, providing new insights into the etiology of gout and promising targets for the development of therapeutic agents.…”
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41451
PARP inhibitors as therapy for small cell lung carcinoma: A systematic review and meta-analysis of clinical trials
Published 2024-01-01“…Poly ADP-Ribose Polymerase inhibitors (PARPi) are novel anti-cancer agents that induce DNA damages and cause cell death in tumor cells with impaired DNA repair, known as the synthetic lethality concept. …”
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41452
Design and evaluation of bromelain-encapsulated alginate beads reinforced with gum Arabic: Formulation, characterization, and stability in simulated gastrointestinal conditions
Published 2025-03-01“…Hydrogel beads containing purified, crude extract and commercial bromelain preparations were developed using encapsulation technique with two carrier agents, sodium alginate and gum Arabic in various ratios of 2:0, 1.5:0.5 and 1:1 (w:w). …”
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41453
Elucidating the role of pyrimidine metabolism in prostate cancer and its therapeutic implications
Published 2025-01-01“…Drug sensitivity analysis further demonstrated that tumors with elevated pyrimidine metabolism displayed increased responsiveness to several chemotherapeutic agents, including BI-2536, JW-7-24-1, and PAC-1, suggesting that targeting pyrimidine metabolism may enhance treatment efficacy. …”
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41454
Chronic inflammatory bowel diseases: the course and treatment methods in Russian Federation (Results of multicenter population-based one-stage observational study)
Published 2018-08-01“…At the moment of enrollments to the study patients received maintenance therapy, most frequently - by the drugs containing 5-aminosalicylic acid (72.0% for UC, 59.5% for CD) and immunosuppressors (28.0% for UC, 42.6% for CD); biological agents are prescribed rarely (11.75% for UC, 20.4% for CD). …”
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41455
Phenotypic effects of different doses of physical and chemical mutagens in cotton plants
Published 2023-01-01“…El objetivo de este estudio fue evaluar la sensibilidad de diferentes agentes mutagénicos en semillas de algodón de la variedad Guazuncho 3. …”
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41456
La opción preferencial por los pobres y la Doctrina Social de la Iglesia. A 50 años de la irrupción de la Teología de la Liberación, de Gustavo Gutiérrez
Published 2022-12-01“…Se concluye con la afirmación de que la OPP, como aporte de la Iglesia latinoamericana a la reflexión teológica de la Iglesia universal, ofrece la concreción necesaria a la enseñanza social de la Iglesia, lo que le ha permitido cambiar su mirada de los pobres y redescubrir que no son solo sujetos de ayuda, sino que pueden ser agentes de su propio destino. Al mismo tiempo, le permite asumir sin cortapisas que la OPP es una categoría teológica y cristocéntrica, anunciarlo así puede ayudar a despertar la conciencia cristiana sobre la necesidad de transformar la realidad, desde los pobres y con los pobres. …”
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41457
Digital breakthrough: will public administration be smart enough in a digital state and how smart are the elite and citizens
Published 2021-10-01“…The model includes a set of public services of a consumer nature with multichannel access and the use of “intelligent agents”. Thirdly, to what extent the subjects of government, acting on behalf of the state, use the provided opportunities. …”
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41458
Characterizing Flow and Structure of Diabetic Retinal Neovascularization after Intravitreal Anti-VEGF Using Optical Coherence Tomography Angiography: A Pilot Study
Published 2021-01-01“…This study evaluates changes of flow and structure of diabetic retinal neovascularization (NV) treated with intravitreal antivascular endothelial growth factor (VEGF) agents using optical coherence tomography angiography (OCTA). …”
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41459
The utilization of the multimodal immunotherapy for the opsoclonus–myoclonus syndrome can reduce relapses and permanent neurological sequelae
Published 2025-02-01“…Abstract Background There is no known effective treatment strategy to prevent relapses and avert permanent neurological sequelae in opsoclonus–myoclonus syndrome (OMS). …”
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41460
Bioinformatics and Deep Learning Approach to Discover Food-Derived Active Ingredients for Alzheimer’s Disease Therapy
Published 2025-01-01“…The top five food sources of these predicted compounds were black walnut, safflower, ginger, fig, corn, and pepper. …”
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