Characteristics of Lung Microbiota in Children’s Refractory Mycoplasma pneumoniae Pneumonia Coinfected with Human Adenovirus B by Wenxiang Zhou, Jinglong Chen, Zhimin Xi, Yanyan Shi, Libo Wang, Aizhen Lu

“…Both M. pneumoniae and human adenovirus (HAdV) are common causative agents of lower respiratory tract infection in children; nonetheless, the lung microbiota in patients with coinfection of HAdV and M. pneumoniae remain unexplored. …”
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Cytotoxic and Antioxidant Effects of Antimalarial Herbal Mixtures by Isaac Dadzie, Shaibu Adams Avorgbedo, Regina Appiah-Opong, Obed Cudjoe

“…The dried samples were tested on human acute T-cell leukemia (Jurkat) and breast adenocarcinoma (MCF-7) cell lines. …”
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Hepatoprotective potential of Tamarindus indica following prenatal aluminum exposure in Wistar rat pups by Helen Ruth Yusuf a , Sunday Abraham Musa a , Abel Nosereme Agbon , Ejike Daniel Eze , Akeem Ayodeji Okesina , Ismail Onanuga , Theophilus Pius , Victor Archibong , Mario Edgar Fernandez Diaz , Juma John Ochieng , Nicholas Kusiima , Bot Yakubu Sunday , Ibe Michael Usman

“…Over time, the use of plant-derived agents in the management of various human health conditions has gained a lot of attention. …”
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Fiscal Decentralisation and the Performance of Health Sector in Kabale District, Uganda. by Ali Khamis, Hashir

“…It was recommended that the government takes steps stem the fragmentation's in health service delivery in the country, provide the needed funding for health service delivery and in the medium to long term, detach the Department of Ministry of Health and create an all new Ministry to encompass and allied agencies in the country, Government must increase more funds in budgeting for the Ministry of Health, MOH should mobilize all health agents to solve problems and challenges facing health sector, MOH should renovate all health buildings, put up more health facilities, improve on transport system, and increase the number of doctors.…”
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Prevalence of Trypanosoma congolense and Trypanosoma vivax in Lira District, Uganda by Aziz, Katabazi, Adamu, Almustapha Aliero, Sarah, Gift Witto, Martin, Odoki, Simon Peter, Musinguzi

“…Trypanosomes are the causative agents of animal African trypanosomiasis (AAT) and human African trypanosomiasis (HAT), the former affecting domestic animals prevalent in Sub-Saharan Africa. …”
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Factors Associated with Hand Washing Practices among Secondary School Students in Ndorwa East Constituency in Kabale District by Benja, Twinomuhwezi

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Dynamic Challenges of Active Tuberculosis: Prevalence and Risk Factors of Co-Infection in Clinical and Microbiological Characteristics at King Abdulaziz University Hospital, Jeddah... by Mokhtar JA, Attallah DM, Jiman-Fatani AA, Al-Rabia MW, Alqarni MA, Saleh BH, Amboon MM, Altorki TA, Alkuwaity KK, Abujamel T, Kaki R, Albarakati TN, Daghistani H, Ismail MA, Alharbi O, Abu ITM, Alfadil A, Ibrahem K, Mufrrih M, Sait AM

“…Immunocompromising conditions, including comorbidities, malignancies, and the use of immunosuppressive agents, are major risk factors for active TB (ATB).Objective: To analyze clinical factors and estimate mortality in TB and drug-resistant cases.Methods: This retrospective study analyzed medical records of 12,494 patients at KAUH (2019– 2021), identifying 131 confirmed TB cases with comprehensive data on demographics, clinical features, comorbidities, diagnostics, and outcomes. …”
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Factors affecting perception and acceptance of colonoscopy in patients with inflammatory bowel disease by Chang-Hung Liao, Peng-Jen Chen, Yu-Lueng Shih, Wei-Kuo Chang, Tsai-Yuan Hsieh, Tien-Yu Huang

“…The patients' perceptions of the four components associated with the colonoscopy procedure (embarrassment, pain, use of bowel-cleansing agents, and stress) were assessed via a questionnaire. …”
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Properties of new polycationic bacteriochlorin photosensitizers: cytotoxicity and interaction with biofilms by Irina Tiganova, Yulia Zhizhimova, Eteri Tolordava, Elena Makarova, Natalia Shevlyagina, Alexander Barmashov, Maria Baryshnikova, Vladimir Zhukhovitsky, Yulia Romanova

“…Aim: Biofilms of pathogenic bacteria are phenotypically resistant to antibiotics and other antimicrobial agents, host immune systems, and adverse environmental conditions, and are responsible for most chronic infections. …”
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Hyaluronic acid-curcumin nanoparticles for preventing the progression of experimental autoimmune uveitis through the Keap1/Nrf2/HO-1 signaling pathway by Weiwei Tang, Xiaomin Huang, Yun-Di Yi, Fan Cao, Manli Deng, Jiawei Fan, Zheng-Xuan Jiang, Li-Ming Tao, Xianwen Wang, Lei Shi

“…In summary, this study revealed that HA-CUR NPs, which are composed of a natural product and biomacromolecules with outstanding artificial antioxidant enzyme activities, may be novel agents for effectively and safely treating uveitis and other ROS-related diseases.…”
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Recombinant factor VIIa: new insights into the mechanism of action through product innovation by Miguel A. Escobar, Maureane Hoffman, Giancarlo Castaman, Cedric Hermans, Johnny Mahlangu, Johannes Oldenburg, Charles L. Percy, Mark T. Reding, Amy D. Shapiro, Steven W. Pipe

“…Management of bleeding in persons with hemophilia and inhibitors involves treatment with bypassing agents, including recombinant activated factor VII (rFVIIa). …”
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The safety, pharmacokinetics and neutralizing activity of recombinant human anti-rabies monoclonal antibody NM57 injection (rhRIG, Ormutivimab) in combination with rabies vaccinati... by Yin Yin, Min Jia, Yufeng Li, Wei Zhao, Shuhong Chen, Peiyuan Huo, Qinghua Zhao, Lan Yu, Cha Wang, Yirui Ma, Meixia Wang, Jing Zhang

“…Background: The combination of passive immune agents (human rabies immune globulin (HRIG) and equine rabies antiserum (ERA)) with vaccines are effective measures for preventing the onset of rabies post exposure. …”
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The patient perspective on transanal irrigation treatment for low anterior resection syndrome after rectal cancer surgery - a qualitative and quantitative study by Boglarka Rethy, Anna Schandl, Caroline Nordenvall, Gabriella Jansson Palmer, Charlotta Bergström, Maria Williamson, Emil Pieniowski, Asif Johar, Pernilla Lagergren, Mirna Abraham-Nordling

“…Patients in the TAI group used less loperamide compared to the control group (36% vs. 79%). The use of bulky agents was similar. The interview text rendered into three main categories: regaining control in everyday life, need for structure and planning and becoming familiar with the procedure. …”
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Efficacy of linaclotide in combination with polyethylene glycol for bowel preparation in Chinese patients undergoing colonoscopy polypectomy: protocol for a randomised controlled t... by Jing Xu, Ping-ping Chen, Dong Chen, Hui-Ying Zhao, Xiao-Feng Cai, Xiao-Bin Wang, Chao-Xu Liu

“…The effectiveness of bowel preparation agents can be hampered by volume and taste, adversely affecting patient compliance and tolerance. …”
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Chitosan nano-formulation enhances stability and bactericidal activity of the lytic phage HK6 by Hasnaa R. Temsaah, Karim Abdelkader, Amr E. Ahmed, Nada Elgiddawy, Zienab E. Eldin, Hend Ali Elshebrawy, Nahed Gomaa Kasem, Fatma A. El-Gohary, Ahmed. F. Azmy

“…Conclusion This suggests that the phage HK6 encapsulated CS-NPs exhibit potentiality as biocontrol agents against resistant microorganisms offering an alternative to phage alone. …”
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Integrative analysis of immunogenic PANoptosis and experimental validation of cinobufagin-induced activation to enhance glioma immunotherapy by Yonghua Cai, Heng Xiao, Shuaishuai Xue, Peng Li, Zhengming Zhan, Jie Lin, Zibin Song, Jun Liu, Wei Xu, Qixiong Zhou, Songtao Qi, Xi’an Zhang, Ziyi Luo

“…Conclusions These findings highlight the therapeutic potential of PANoptosis-targeting agents, such as cinobufagin, in combination with immunotherapy, offering a promising approach to convert “cold” tumors into “hot” ones and improving glioma treatment outcomes.…”
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The Effect of Polyurethane Film Versus Apis Dorsata Honey Spray for Wound Dressing Following Long Bone Fractures Osteosynthesis by Surianty Shafei, Mohd Ariff Sharifudin, Shaifuzain Ab Rahman, Abdul Nawfar Sadagatullah

“…Honey-based dressings can be used as prophylactic agents. Methods: This prospective, randomized clinical study was designed to compare the effect of conventional polyurethane film and Apis dorsata honey spray as dressing materials after long bone fracture osteosynthesis. …”
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Study on the Adsorption Mechanism of Hydrophobic SiO2 Nanoparticles: A Molecular Dynamics Study by Runnan Zhou, Yuyuan Wang, Dong Zhang, Peng Ye, Jianguang Wei

“…As a result, nanoparticles (NPs) have found a promising role in enhanced oil recovery as potential improved oil recovery agents in low permeability. Despite many experiments that have proved that nanoparticles can be adsorbed on the rock surface in a macroscopic perspective, the adsorption mechanism and the effects of molecular structure on the adsorption behavior of nanoparticles on rock surfaces remain scarce. …”
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Advancements related to probiotics for preventing and treating recurrent respiratory tract infections in children by Yali Zhang, Yali Zhang, Yingying Xu, Yingying Xu, Ling Hu, Ling Hu, Xiaomei Wang

“…Probiotics have recently emerged as promising agents for modulating intestinal microecology and have gained considerable attention in clinical research on preventing and treating RRTIs in children. …”
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Advanced heart failure: guideline‐directed medical therapy, diuretics, inotropes, and palliative care by Daniela Tomasoni, Julie K.K. Vishram‐Nielsen, Matteo Pagnesi, Marianna Adamo, Carlo Mario Lombardi, Finn Gustafsson, Marco Metra

“…Some new treatments acting on cardiac function may fulfil both these needs. Inotropic agents acting through an increase in intracellular calcium have often increased risk of death. …”
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