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40041
PPARγ Signaling Mediates the Evolution, Development, Homeostasis, and Repair of the Lung
Published 2012-01-01“…By exploiting such deep cell-molecular functional homologies as targets for leveraging lung homeostasis, we have discovered that we can effectively prevent and/or reverse the deleterious effects of these pathogenic agents, demonstrating the utility of evolutionary biology for the prevention and treatment of chronic lung disease. …”
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40042
Pharmacological Therapy in the Heart as an Alternative to Cellular Therapy: A Place for the Brain Natriuretic Peptide?
Published 2016-01-01“…Indeed, differentiation and/or proliferation of cardiac precursor cells is controlled by various endogenous mediators, such as growth factors and cytokines, which could thus be used as pharmacological agents to promote regeneration. To illustrate such approach, we present recent results showing that the exogenous administration of the natriuretic peptide BNP triggers “endogenous” cardiac regeneration, following experimental myocardial infarction.…”
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40043
Towards Transformation of the Nigerian Youths: The Place of Yoruba Popular Music
Published 2023-11-01“…Since music is said to have an emotional and psychological influence on human minds, this paper, therefore, examines the text content of and relevance of popular music in Nigerian society and highlights the role played by popular musicians as agents for positive transformation of the youths among the Southwestern part of Nigeria. …”
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40044
Conocer La Pampa
Published 2024-06-01“… El derrotero intelectual de Enrique Stieben nos sirve como disparador para adentramos en la problemática de la producción de narrativas y los usos del pasado en espacios subnacionales, lugares donde la generación de conocimientos adquirió ritmos e interacciones multiescalares que involucraron a los intelectuales con agentes políticos, la prensa del Territorio Nacional de La Pampa y distintos espacios de sociabilidad. …”
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40045
ANÁLISIS DEL TURISMO GASTRONÓMICO EN LA PROVINCIA DE CÓRDOBA
Published 2012-01-01“…Esta investigación analiza las rutas gastronómicas existentes en la provincia de Córdoba que están sustentadas sobre cinco productos clave: el aceite de oliva, el vino, el jamón ibérico, el mantecado y el anís. …”
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40046
Efectos fisiopatológicos del tabaquismo como factor de riesgo en la enfermedad periodontal
Published 2016-05-01“…El hábito de fumar es un agente etiológico en la transición hacia la periodontitis, porque actúa sobre la formación de la placa dentobacteriana, y en la respuesta inflamatoria, debido a los efectos nocivos de los componentes del tabaco, se destaca su acción vasoconstrictora y su actividad osteoclástica. …”
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40047
Evaluation of Virtual Commerce Applications for the Metaverse Using Spherical Linear Diophantine-Based Modeling Approach
Published 2024-01-01“…Criterion weighting results reveal that “ease of navigation” and “recommendation agents” are the most significant criteria in assessing v-commerce solutions. …”
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40048
Réflexion sur l'organisation dans une nouvelle optique. Enquête sur le fondement ontologique de l'organisation
Published 2024-02-01“…Cet article propose une théorie de l'organisation qui se prête à l'étude du changement en attirant l'attention sur deux phénomènes quelque peu négligés, à savoir : l'origine de la hiérarchie dans la communication et le rôle joué par cette dernière dans la constitution de l'identité de l'organisation en tant qu'agente. L’auteur soutient que l'organisation débute sous le couvert d’une coorientation vers un objet commun, caractérisée par des relations de mandant·e à mandataire. …”
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40049
Study of Molecular Interactions, Optical, and Structural Properties through the Green Synthesis of Selenium Oxide Nanoparticles from Hibiscus sabdarriffal: Biocompatibility for Bio...
Published 2024-12-01“…Conclusions: The utilization of selenium oxide nanocrystals as antibacterial agents has yielded diverse outcomes, demonstrating their remarkable efficacy in combatting Klebsiella spp.…”
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40050
Efecto de pies clonales sobre el crecimiento y productividad en manzano cv Cripps Pink en el Alto Valle de Río Negro y Neuquén
Published 2022-01-01“…La combinación EM9/MM111 presenta valores productivos aceptables por lo que podría ser una alternativa interesante en aquellos lugares donde las condiciones del suelo no permiten el uso de portainjertos de bajo vigor.…”
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40051
Metastatic Lesion of the Tibia from Renal Cell Carcinoma
Published 2021-01-01“…The patient arrived at the emergency department with a primary complaint of left ankle pain. Ankle X-rays demonstrated a lytic lesion involving the medial malleolus with possible metastatic disease. …”
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40052
More on search for causes of sensitization to tuberculin PPD for mammals in cattle
Published 2021-11-01“…Many specialists are still of the view, formulated when studying causes of pseudoallergic reactions, that the agents of actinomycosis, trematode infections etc. can cause sensitization of the animal body to tuberculin PPD for mammals. …”
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40053
Quadriceps Activation After Anterior Cruciate Ligament Reconstruction: The Early Bird Gets the Worm!
Published 2024-08-01“…Early management focusing on pain modulation through modalities like ice, compression, and pharmacological agents help mitigate the inflammatory response and alleviate pain, thereby reducing the reflexive inhibition of quadriceps. …”
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40054
Utilizing Cytokines to Function-Enable Human NK Cells for the Immunotherapy of Cancer
Published 2014-01-01“…Here, we review the roles of major cytokines that regulate human NK cell development, survival, and function, including IL-2, IL-12, IL-15, IL-18, and IL-21, and their translation to the clinic as immunotherapy agents. We highlight a recent development in NK cell biology, the identification of innate NK cell memory, and focus on cytokine-induced memory-like (CIML) NK cells that result from a brief, combined activation with IL-12, IL-15, and IL-18. …”
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40055
The Development and Intellectualisation of African Languages Revisited.
Published 2024“…Among the challenges faced by those who want to promote and intellectualise African languages, the issue of the Africans’ mindset and the phenomenon of globalization, with English as one of the globalising agents, are highlighted. Finally, strategies to counter the challenges are proposed, including political will, appropriate policies and the creation of universities using only African languages as media of instruction.…”
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40056
Anaplastic Thyroid Carcinoma: A ceRNA Analysis Pointed to a Crosstalk between SOX2, TP53, and microRNA Biogenesis
Published 2015-01-01“…In detail, silencing SOX2 in SW1736 is able to suppress the expression of the stem markers analysed, strongly sensitizing the line to treatment with chemotherapeutic agents. Therefore, in order to further investigate the role of SOX2 in ATC, a competing endogenous RNA (ceRNA) analysis was conducted in order to isolate new functional partners of SOX2. …”
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40057
Osteodifferentiation of Human Preadipocytes Induced by Strontium Released from Hydrogels
Published 2012-01-01“…In conclusion, the use of biomaterials able to release in situ osteoinductive agents, like Sr2+, could represent a new strategy for future applications in bone tissue engineering.…”
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40058
Metabolomics profiling reveals p-aminobenzoic acid enhances resistance to Fusarium head blight in wheat
Published 2025-02-01“…These results provide preliminary insights into the metabolic basis of resistance in Lianmai12 and will be beneficial in the development of potential biocontrol agents against FHB. Graphical Abstract…”
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40059
Addressing the toxic chemicals problem in plastics recycling
Published 2025-01-01“…Plastics contain a vast range of chemicals, including monomers, polymers, processing agents, fillers, antioxidants, plasticizers, pigments, microbiocides and stabilizers. …”
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40060
Current Status of Gout Arthritis: Current Approaches to Gout Arthritis Treatment: Nanoparticles Delivery Systems Approach
Published 2025-01-01“…A new development in the approach to gout is that of NLRP3-targeted biologic agents, such as monoclonal therapies, to provide more accurate treatment by blocking specific pro-inflammatory cytokines. …”
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