Early temperature records from a Norwegian coastal farm (1880–1930) by Ann Rigmor Nerheim

“…The data are based on diary notes of weekly temperature ranges. Maximum and minimum temperatures have been investigated, as well as weekly, monthly, and yearly average temperatures. …”
Get full text

Double-blind, randomized, placebo-controlled pilot clinical trial with gamma-band transcranial alternating current stimulation for the treatment of schizophrenia refractory auditor... by Xiaojuan Wang, Xiaochen Zhang, Yuan Chang, Jingmeng Liao, Shuang Liu, Dong Ming

“…Auditory hallucination symptom scores and 64-channel electroencephalograms were measured at baseline, week2, week4 and follow-up. For clinical symptom score, we observed a significant interaction between group and time for auditory hallucinations symptoms (F(3,90) = 26.964, p < 0.001), and subsequent analysis showed that the 40Hz-tACS group had a higher symptom reduction rate than the sham group at week4 (p = 0.036) and follow-up (p = 0.047). …”
Get full text

Influencing basic behavioral mechanisms of action while targeting daily walking in sedentary adults at risk for cardiovascular disease: randomised factorial design protocol by Karina W Davidson, Ying Kuen Cheung, Joan Duer-Hefele, Jerry Suls, Ashley M Goodwin, Samantha Gordon, Ravneet Sahni, Frank Vicari, Kaitlyn Accardi, Salvatore Crusco, Ciaran Friel, Elizabeth A Vrany

“…Following a 4-week run-in period to confirm sedentary behaviour and adherence to the study protocol, 624 eligible participants will be randomised to an 8-week intervention period. …”
Get full text

Valerenic acid ameliorates amphetamine-related neurotoxicity by improving hypothalamus tyrosine hydroxylase and histamine-N-methyl transferase enzymes by Khaled M.M. Koriem, Ammar H.A. Naiem

“…METH-treated, VA (5 mg/kg) prior to METH-treated, and VA (10 mg/kg) before METH-treated groups: normal rats were oral administrated with METH (2.5 mg/kg), 3 days/week for 3 weeks, where the last two groups were oral administrated daily during four weeks at 5 mg/kg and 10 mg/kg VA, starting one week prior to METH administration. …”
Get full text

Analysis of the terms of development of infectious complications in patients after osteosynthesis of long bones by P.V. Tanasienko, H.B. Kolov, V.M. Tsokalo

“…In 51.5% of patients of the first group after closed fractures, infectious complications were detected in the first 6 weeks after surgery. In 43.7% of patients of this group, manifestations of the inflammatory process occurred in the period from 6 weeks to 1 year. …”
Get full text

P-glycoprotein and/or Histone Deacetylase 2 Regulates Steroid Responsiveness in Childhood Nephrotic Syndrome by Harshit Singh, Narayan Prasad, Durga Prasanna Misra, Akhilesh Kumar Jaiswal, Vikas Agarwal

“…Materials and Methods: Thirty-one patients were recruited at baseline (n = 31) (before initiating steroid therapy); after 6 weeks of steroid therapy, 24 patients achieved remission (steroid-sensitive NS [SSNS] n = 24 mean age, 7.96 ± 3.90), whereas seven patients were resistant to steroids (SRNS, n = 7, mean age 10.00 ± 3.55). mRNA expression of HDAC2 and P-gp and functional analysis of P-gp and enzymatic activity of HDAC2 were analyzed at baseline, and at 6 weeks of steroid treatment and at the time of relapse. …”
Get full text

How learning to read Braille in visual and tactile domains reorganizes the sighted brain by Maciej Gaca, Alicja M. Olszewska, Dawid Droździel, Agnieszka Kulesza, Małgorzata Paplińska, Bartosz Kossowski, Katarzyna Jednoróg, Jacek Matuszewski, Aleksandra M. Herman, Artur Marchewka

“…Interestingly, VWFA activation was observed after 1 week in the visual domain but only after 6 weeks in the tactile domain. …”
Get full text

Delayed Antiretroviral Therapy (ART) Initiation among Hospitalized Adults in a Resource-Limited Settings: A Challenge to the Global Target of ART for 90% of HIV-Infected Individual... by Prossie Merab Ingabire, Fred Semitala, Moses R. Kamya, Damalie Nakanjako

“…Phone calls were made to patients that had left the hospital by the end of the two-week period. Delayed cART initiation was defined as failure to initiate cART within two weeks. …”
Get full text

Investigating a caregiver-assisted social skills group programme for primary and early high school-aged children with acquired brain injury or cerebral palsy: protocol for a pilot... by Koa Whittingham, Roslyn N Boyd, Rose Gilmore, Leanne Sakzewski, Nicola Hilton, Afroz Keramat, Bianca Thompson, Jacqui Barfoot, Christine T Moody

“…The primary outcome will measure individualised social participation goals on the Canadian Occupational Performance Measure immediately postintervention at the primary endpoint (12 weeks). Secondary outcomes include the Social Skills Improvement System Social-Emotional Learning Edition Rating Forms and Quality of Play Questionnaire immediately postintervention, 12 weeks postintervention (26 weeks postbaseline), 36 weeks postintervention (52 weeks postbaseline) for retention. …”
Get full text

Efficacy and Safety of Allisartan Isoproxil/Amlodipine in Patients With Essential Hypertension Uncontrolled by Amlodipine: A Phase III, Multicenter, Double‐Blind, Parallel‐Group, R... by Hongjie Chi, Xin Zhang, Shumei Ma, Gang Pan, Xiaojuan Lian, Yan Chen, Haotian Pei, Zichen Liu, Xiangmin Lin

“…This 12‐week double‐blind period was followed by an open‐label extension of ALI/AML treatment through week 52. …”
Get full text

Associations between caregivers’ health behaviours and overweight/obesity among children aged 2–6 years in Beijing, China: a cross-sectional study by Yan Hu, Juan Du, Wenjing Ji, Xueling Li, Aimin Liang, Xiwei Xu

“…Additionally, children whose caregivers consumed sweets 2–3 times/week (OR 1.535, 95% CI 1.133 to 2.081) or ≥4 times/week (OR 1.916, 95% CI 1.258 to 2.918), as well as children whose caregivers consumed fast food ≥4 times/week (OR 2.298, 95% CI 1.349 to 3.914), were more likely to be overweight and obesity than children whose caregivers consumed these foods ≤1 time/week. …”
Get full text

Gameplay and physical activity behaviors in adult video game players by Haylei Scoggins, Ryan R. Porter, Robyn Braun-Trocchio

“…The participants spent over five days per week and an average of 26.56 h per week playing video games. …”
Get full text

Effects of prenatal exercise interventions on maternal body composition: A secondary analysis of the FitMum randomized controlled trial. by Caroline Borup Roland, Parisa Seyedhosseini, Signe de Place Knudsen, Anne Dsane Jessen, Ida Karoline Bach Jensen, Jane M Bendix, Gerrit van Hall, Stig Molsted, Saud Abdulaziz Alomairah, Ellen Løkkegaard, Bente Stallknecht, Tine D Clausen

“…The main objective of the study was to investigate the effects of prenatal exercise interventions on maternal body composition at 28 weeks gestation and 7-14 days after delivery. We also explored associations between physical activity (PA) per se and body composition. …”
Get full text

Evaluation of gestational nonpersistent pesticide exposure with newborn size and gestational length in rural Ghana using a novel time-varying extension of multiple informant models by Wylie BJ, Kaali S, Duttweiler L, Ae-Ngibise KA, Mujtaba M, Tawiah C, Gibson E, Calafat AM, Ospina M, Jack DJ, Agyei O, Lee AG, Roberts DJ, Boamah-Kaali EA, Factor-Litvak P, Modest AM, Hauser R, Coull BA, Asante KP

“…In time-varying models, significant associations were identified for pyrethroid exposure measured between weeks 16–27, and for 2,4-D exposure measured during weeks 25–33. …”
Get full text

Changes in household purchasing of soft drinks following the UK soft drinks industry levy by household income and composition: controlled interrupted time series analysis, March 20... by Jean Adams, Martin White, Stephen J Sharp, Harry Rutter, David Pell, Steven Cummins, Richard D Smith, Nina Trivedy Rogers

“…We examined changes in volume of and amount of sugar in purchases of soft drinks according to household income and composition, 19 months following the implementation of the UK soft drinks industry levy.Methods Data were from the Kantar Fast Moving Consumer Goods panel, a market research panel which collects data on weekly household purchases (mean weekly number of households=21 908), March 2014–November 2019. …”
Get full text

Temporary Mental Nerve Paresthesia Originating from Periapical Infection by Ozgur Genc Sen, Volkan Kaplan

“…Resolution of the paresthesia began two weeks after conventional root canal treatment associated with antibiotic therapy and was completed in eight weeks. …”
Get full text

The effect of sulthiame on potential biomarkers in moderate to severe obstructive sleep apnoea by Erik Hoff, Saliha Musovic, Ali M. Komai, Ding Zou, Christian Strassberger, Kaj Stenlöf, Ludger Grote, Jan Hedner

“…Patients with moderate to severe OSA, body mass index 20–35 kg·m−2, aged 18–75 years and not accepting positive airway pressure treatment were randomised to 4 weeks with placebo, STM 200 mg or STM 400 mg. CA activity (n=43) and HIF-1α concentration (n=53) were determined at baseline, after 4 weeks of treatment and 2 weeks after treatment completion. …”
Get full text

Dietary Supplemental Glutamine Enhances the Percentage of Circulating Endothelial Progenitor Cells in Mice with High-Fat Diet-Induced Obesity Subjected to Hind Limb Ischemia by Chi-Hsuan Ko, Sung-Ling Yeh, Chiu-Li Yeh

“…Mice in the HC and HI groups were fed a high-fat diet which 60% energy provided by fat for 8 weeks. Mice in the HG group were fed the same diet for 4 weeks and then transferred to a high-fat diet with 25% of total protein nitrogen provided as GLN to replace part of the casein for the subsequent 4 weeks. …”
Get full text

Clinical Progression and Load Management For Proximal Hamstring Tendinopathy In A Long-Distance Runner: A Case Report by Cristina Campos-Villegas, Lucía Ortega-Pérez de Villar, Javier Gámez-Payá, Jorge Alarcón-Jiménez, Nieves de Bernardo

“…Function increased at 6 weeks and at 12 weeks (VISA-H from 23, to 53, to 80). …”
Get full text

Improvement of Fatigue in Patients with Ankylosing Spondylitis Receiving Tofacitinib: Analyses of a Phase 3 Randomized Controlled Trial by Laure Gossec, Jessica A. Walsh, Raj Sengupta, Andrew G. Bushmakin, Joseph C. Cappelleri, Arne Yndestad, Oluwaseyi Dina, David Cella

“…The rapidity of improvement was assessed by time-to-event analyses (nonparametric Kaplan–Meier models); initial improvement events (i.e., time to first week of FACIT-F improvement) and stable improvement events (i.e., time to first week of FACIT-F improvement, sustained to 16 weeks) were examined. …”
Get full text