Xixin Decoction’s novel mechanism for alleviating Alzheimer’s disease cognitive dysfunction by modulating amyloid-β transport across the blood–brain barrier to reduce neuroinflamma... by Chaokai Yang, Enlong Zhao, Hu Zhang, Liqi Duan, Xinyue Han, Hongli Ding, Yan Cheng, Dengkun Wang, Dengkun Wang, Dengkun Wang, Xiaojing Lei, Xiaojing Lei, Xiaojing Lei, Yongchang Diwu, Yongchang Diwu, Yongchang Diwu

“…In vivo, SAMP8 mice were administered various doses of XXD via gavage for 8 weeks, including high-dose XXD group (H-XXD) at 5.07 g kg-1·d-1, medium-dose XXD group (M-XXD) at 2.535 g kg-1·d-1, and low-dose XXD group (L-XXD) at 1.2675 g kg-1·d-1. …”
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Effect of Enriched Feed by n-3 fatty acids and 2% of n-6 fatty acid on Danio rerio Reproduction by N.B.P Utomo, L. Nurmalia, I. Mokoginta

“…Results shows that at the fifth weeks of this experiment, gonad of fish fed on 1.0 % of n-3 fatty acid and 2.0 % n-6 fatty acid already produce eggs with the some size, while others. …”
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Integrating Videoconferencing Therapist Guidance Into Stepped Care Internet-Delivered Cognitive Behavioral Therapy for Child and Adolescent Anxiety: Noninferiority Randomized Contr... by Sonja March, Susan H Spence, Larry Myers, Martelle Ford, Genevieve Smith, Caroline L Donovan

“…This noninferiority randomized trial compared ICBT-SC[VC] to an ICBT-TG[VC] program, with assessments conducted at baseline, 12 weeks, and 9 months after treatment commencement. …”
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Effect of maturity status on lower-limb strength testing reliability in academy football players from an elite professional club by Maxime Violin, Abd-elbasset Abaïdia, Guillaume Rave, Sébastien Ratel

“…After at least two familiarization sessions, they performed five maximum strength tests involving adductor, abductor, posterior or anterior chain muscles, each twice, one week apart. Intraclass correlation coefficient (ICC) and coefficient of variation (CV) were calculated for each test. …”
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Safety and tolerability of the M2 muscarinic acetylcholine receptor modulator BAY 2413555 in heart failure with reduced ejection fraction in the REMOTE-HF study by Marat Fudim, Muhammad Shahzeb Khan, Dominik Linz, JoAnn Lindenfeld, Calum MacRae, Nina Kimmeskamp-Kirschbaum, Michaela Meyer, Thomas Mondritzki, Hanna Tinel, Wilfried Dinh, Robert J. Mentz

“…Secondary endpoints included number of participants with high degree AV block or symptomatic pauses/ bradycardia and changes from baseline in resting heart rate after 2 and 4 weeks of dosing with BAY 2413555. Changes from baseline in heart rate recovery (HRR) at 1 and 2 min after exercise testing and chronotropic reserve (CR) were also assessed. …”
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Effects of open-skill exercise on executive functions in children and adolescents: a systematic review and meta-analysis by Shunding Hu, Peng Shi, Ziyun Zhang, Xiaosu Feng, Kai Zhang, Kai Zhang, Kai Zhang, Teng Jin

“…In addition, moderate-intensity and higher-frequency exercises overall have a more positive effect on promoting executive functions (p < 0.05); interventions of 6 to 10 weeks are more effective for working memory (p < 0.05), while 30-min sessions are the most effective for working memory (p < 0.05), and sessions lasting 75 to 120 min are the most effective for cognitive flexibility (p < 0.05). …”
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Perbedaan Rasio Kolesterol Total/ HDL Kelompok Kontrol dan Kelompok Diet Tinggi Minyak Sawit pada Tikus Wistar by Yelsa Yulanda Putri, Ellyza Nasrul, Susila Sastri

“…High-palm oil diet (50% palm oil, 3ml/day) was given to the group P for four weeks. Analysis of data using independent t test. …”
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Growth performance and gut health of Murrah buffalo calves fed with developed novel synbi- otic formulation by Antony J. Thanippilly, Sachin Kumar, Vinay V. Varada, Nitin Tyagi, Ashish K. Samanta

“…All the calves had ad libitum access to a basal diet, having calf starter (from the second week onwards), green forage (maize and sorghum), and fresh, clean water throughout the experimental period. …”
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Effect of Suspension Massage Exercise Technique on Core Muscle Mass and Postural Control Ability of Patients with Stroke by SUN Jie, CHEN Guijuan, XU Han, ZHANG Tianyu, DING Yi, WANG Shurui, LI Li

“…The control group received conventional rehabilitation treatment, while the experiment group received suspension massage exercise techniques in addition to the treatment received in the control group. Before and four weeks after treatment, patients were evaluated with the Postural assessment scale for stroke patients (PASS), the Berg balance scale (BBS), the Fugl-Meyer assessment lower extremity (FMA-LE), and the modified Barthel index (MBI). …”
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D-mannose alleviates chronic periodontitis in rats by regulating the functions of neutrophils by Xue Li, Xueting Chen, Qingyu Zhu, Pengye Zhang, Shunxue Nan, Lei Lv, Shengcai Qi

“…Methods To explore the protective effects of D-mannose on chronic periodontitis, the eight-week-old Sprague Dawley rat model of lipopolysaccharide (LPS)-induced periodontitis was established, followed by D-mannose treatment by oral gavage. …”
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Effects of exercise interventions on fatigue of hematopoietic stem cell transplantation patients: A Meta-analysis (运动干预对造血干细胞移植患者疲乏影响的Meta分析)... by ZHOU Min (周敏), ZHANG Qing (张清), HU Shaoyan (胡绍燕), ZHOU Xuemei (周雪梅)

“…Results A total of six studies were included, and the results of meta-analysis showed a statistically significant difference in fatigue scores between the experimental and control groups ［SMD= -0. 24, 95% CI (-0. 44, -0. 03), P<0. 001］; subgroup analysis showed that exercise intervention improved fatigue in HSCT patients ［SMD= -0. 58, 95% CI (-0. 80, -0. 35), P<0. 001］; exercise interventions throughout the transplant period ［SMD= -0. 58, 95% CI (-0. 80, -0. 35), P<0. 001］, and duration longer than 12 weeks ［SMD= -0. 53, 95% CI (-0. 78, -0. 29), P<0. 001］ can reduce fatigue. …”
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The Effect of Prejudice and Discrimination Education Given to University Students on Gender Perception and Attitude by Neslihan Nur Pehlivan

“…Afterwards, a fourteen-week course period on "Prejudice and Discrimination" was carried out. …”
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Evaluating the Effectiveness of InsightApp for Anxiety, Valued Action, and Psychological Resilience: Longitudinal Randomized Controlled Trial by Victoria Amo, Falk Lieder

“…MethodsWe conducted a randomized controlled trial with 228 participants (completion rate: n=197, 86.4%; mean age 38, SD 11.50 years; age range 20-80 years; female: n=101, 52.6%; and White: n=175, 91.1%), who were randomly assigned to either the treatment or the active placebo control group. During the 1-week intervention phase, the treatment group engaged with InsightApp, while participants in the control group interacted with a placebo version of the app that delivered executive function training. …”
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Fostering positive affective exercise experiences and affect-related competencies for a physically active lifestyle: The FEEL Project – Results of the Pilot-Study by Martin Robert Bührer, Stephanie Rosenstiel, Gorden Sudeck, Julia Schmid

“…The FEEL program addresses this gap. The 8-week intervention aims to promote positive affective exercise experiences (Ekkekakis et al., 2021), affect regulation competence, well-being and, consequently, exercise and sport. …”
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Initial clinical experience with [177Lu]Lu-PNT2002 radioligand therapy in metastatic castration-resistant prostate cancer: dosimetry, safety, and efficacy from the lead-in cohort o... by Aaron R. Hansen, Stephan Probst, Jean-Mathieu Beauregard, Benjamin L. Viglianti, Jeff M. Michalski, Scott T. Tagawa, Oliver Sartor, Ronald F. Tutrone, Orhan K. Oz, Kevin D. Courtney, Ebrahim S. Delpassand, Luke T. Nordquist, Medhat M. Osman, Kim N. Chi, Richard Sparks, Noble George, Sara M. Hawley, Wenting Wu, Jessica D. Jensen, Neil E. Fleshner

“…Participants received up to 4 cycles of [177Lu]Lu-PNT2002 at 6.8 GBq (± 10%) intravenously per cycle every 8 weeks. Dosimetry (planar + SPECT/CT [n=7]; planar only [n=20]), safety, prostate-specific antigen (PSA) response, objective response rate (ORR), and radiographic progression-free survival (rPFS) per blinded independent central review were assessed.ResultsOf 34 individuals screened, 32 underwent PSMA-PET/CT; 27 met all eligibility criteria. …”
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Chain-mediated effect of physical activity between Chinese language-based L2 motivational self-system and intended effort by Zixia Bu, Yu Liu, Yi Ba, Shan Jiang, Huijuan Liu, Jiyuan Li, Fuqiang Dong, Haohan Yu, Xindi Zhao

“…According to the SEM test, in addition to the direct effect of L2MSS on intended effort, the following paths existed: (1) ILS→PA→IE (effect=-0.265, ratio = 31.28%, 95%CI=[0.124, 0.527]), (2) OLS→PA→IE (effect = 0.179, ratio = 17.94%, 95%CI=[0.074, 0.256]), (3) ILS→PA→LE→IE (effect = 0.116, ratio = 10.69%, 95%CI=[0.042, 0.248]), (4) OLS→PA→LE→IE (effect = 0.108, ratio = 4.15%, 95%CI=[0.039, 0.126]). total indirect effect为0.304 (ratio = 59.61%, 95%CI=[0.069, 0.289]). (1) PA had an ameliorative effect on L2MSS, learning experience, and intended effort, and increasing PA level increased the significance of this effect. (2) PA level positively predicts L2MSS, learning experience, and intended effort. (3) PA is an important mediator in the process of L2MSS that influences the learning experience and intended effort, so MPA at least 3 days a week can increase the efficiency of second language learning. …”
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Optimization and Evaluation of Conditions for Orthotopic Nude Mouse Models of Human Liver Tumor Cells by MENG Yu, LIANG Dongli, ZHENG Linlin, ZHOU Yuanyuan, WANG Zhaoxia

“…Different concentrations (8×106, 2.4×107, 7.2×107 cells/mL) and resuspension media (PBS, Matrigel) of human liver tumor cell suspensions HepG2-LUC and Hep3B-LUC were orthotopically inoculated into the liver lobes of 5-week-old female BALB/c nude mice (12 groups, 7 mice each) to construct human liver tumor nude mouse orthotopic cancer models. …”
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Locking compression plate as a sequential external fixator following the distraction phase for the treatment of tibial bone defects caused by fracture-related infection: experience... by Xiriaili Kadier, Kai Liu, Aierbanjiang Shali, Yimurang Hamiti, Sulong Wang, Xin Yang, Alimu Keremu, Aihemaitijiang Yusufu

“…Following the completion of distraction, the Ilizarov apparatus or monorail fixator was retained for an additional 2.20 ± 0.53 weeks before being exchanged for the external locking compression plate (ELCP). …”
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Evaluation of dietary coffee Coffee canephora husk supplementation on the growth, blood chemicals, and antioxidative activity of red Nile tilapia Oreochromis sp. by Azmi Afriansyah, Mia Setiawati, Muhammad Agus Suprayudi, Ichsan Achmad Fauzi

“…Fish were reared for 8 weeks and fed three times a day. Parameters observed contained growth performance and antioxidative activity. …”
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Effect of auricular holographic copper-plate scrapping combined with auricular acupoint pressing therapy in the treatment of nonspecific low back pain of cold-dampness obstruction... by REN Fang (任芳), ZHOU Haiying (周海英), BAI Yang (白洋), LI Lijuan (李利娟)

“…All patients received routine treatment and nursing, and those in the observation received auricular holographic copper-plate scrapping combined with auricular acupoint pressing therapy for three weeks. The Numerical Rating Scale (NRS) of pain and Tradition Chinese Medicine syndrome score were compared between two groups. …”
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