Dose-response associations of device-measured sleep regularity and duration with incident dementia in 82391 UK adults by Wenxin Bian, Raaj K. Biswas, Matthew N. Ahmadi, Yu Sun Bin, Svetlana Postnova, Andrew J. K. Phillips, Nicholas A. Koemel, Jean-Philippe Chaput, Shantha M. W. Rajaratnam, Peter A. Cistulli, Emmanuel Stamatakis

“…Device-based sleep duration (h/day) and sleep regularity index (SRI), a metric ranging from 0-100 that quantifies a person’s sleep regularity (with a greater value indicating higher consistency), were calculated from wrist-worn accelerometry data recorded over the course of one week. Incident all-cause dementia cases were obtained from national hospital admission, primary care and mortality data followed up to 30 November 2022. …”
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HIV self-testing positivity rate and linkage to confirmatory testing and care: a telephone survey in Côte d’Ivoire, Mali, and Senegal by Kra, Arsène Kouassi, Fotso, Arlette Simo, Rouveau, Nicolas, Maheu-Giroux, Mathieu, Boily, Marie-Claude, Silhol, Romain, d’Elbée, Marc, Vautier, Anthony, Larmarange, Joseph

“…Of the 27 who reported a consistent reactive response in the first phase, 15 (56%, 95%CI: 36 to 74%) underwent confirmatory HIV testing, with 12 (80%) confirmed as HIV-positive, all of whom began antiretroviral treatment.The confirmation rate of HIVST results was fast, with 53% doing so within a week and 91% within three months of self-testing. …”
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Premalignant features of the prostate can be ameliorated by Uvaria chamae root extract: Modeling prostate cancer with cadmium and alternative treatment option in adult Wistar rats by Edem GD, Sakpa CL, Ezeuko VC

“…Group 1 received water and diet alone, group 2 received 3mg/kg of cadmium alone once weekly for 28days. Group 3-6 received 3mg/kg of cadmium for 28days followed by 150mg/kg of casodex, 2500mg/kg, 1500mg/kg and 1000mg/kg of Uvaria chamae root extract respectively for 28days. …”
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Severe pregnancy-associated atypical hemolytic uremia syndrome in the context of the COVID-19 pandemic: a novel survival case report by Yan Yang, Xiao-jin Li, Hua-Yan Yuan, Jing-Jing Xiong, Peng-Fei Li, Zhen Wang

“…Case presentation A 26-year-old patient with a history of four pregnancies and one delivery (P4G1) presented at 30 weeks and 2 days of gestation with vaginal fluid leakage and fetal growth restriction detected by ultrasound at a different hospital. …”
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Xiaohua Funing decoction ameliorates non-alcoholic fatty liver disease by modulating the gut microbiota and bile acids by Jindong Zhao, Jindong Zhao, Yan Li

“…There were eight rats in each group, and the treatment lasted for 12 weeks. Furthermore, metagenomic sequencing and BA metabolomic analyses were performed.ResultsCompared to the Con group, the Mod group presented significant differences in body and liver weights; serum total cholesterol (TC) and triglyceride (TG) levels; and liver TG, TC, and bile salt hydrolase levels (p < 0.05 or p < 0.01). …”
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Investigation of antioxidant capacity in farmed beluga (Huso huso) fingerling fed with Echinacea purpurea and garlic (Allium sativum) powder extracts by Soheil Bazari Moghadam, Forouzan Bagherzadeh Lakani, Jalil Jalilpoor, Mehdi Masoumzadeh

“…Materials and methods: A total of 210 fish with an average weight of 27.74 ± 0.26 g were randomly placed in twenty one 500-L fiberglass tanks, and fed with basal diet supplemented with powder extracts in seven treatments (with three replications) including control (without adding garlic and E. purpurea), treatment 1 = 250 mg/kg garlic, treatment 2 = 500 mg/kg garlic, treatment 3 = 1000 mg/kg garlic, treatment 4 = 250 mg/kg E. purpurea, treatment 5 = 500 mg/kg E. purpurea, treatment 6 = 1000 mg/kg E. purpurea for 8 weeks. At the end of experiment, the amount of catalase, GPX, SOD and MDA enzymes was measured in six fish per treatment. …”
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Association between exposure to tobacco information through mass media, smoking households and secondhand smoke exposure in adolescents: Survey data from South Korea by Wenbin Du, Gaoran Chen, Minmin Gu, Huixin Deng, Won G. Choi

“…Results SHS exposure duration of Korean adolescents in households was 0.88 days per week. The households with smokers including the father (β=1.087; 95% CI: 1.0–1.126), mother (β=1.461; 95% CI: 1.379– 1.543), siblings (β=0.545; 95% CI: 0.493–0.597), grandparents (β=0.224; 95% CI: 0.174–0.272), and other relatives (β=0.170; 95% CI: 0.126–0.214), showed a positive association with SHS exposure in adolescents within the household. …”
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Burden of early neonatal mortality in Sub-Saharan Africa. A systematic review and meta-analysis. by Natnael Moges, Anteneh Mengist Dessie, Denekew Tenaw Anley, Melkamu Aderajew Zemene, Natnael Atnafu Gebeyehu, Getachew Asmare Adella, Gizachew Ambaw Kassie, Misganaw Asmamaw Mengstie, Mohammed Abdu Seid, Endeshaw Chekol Abebe, Molalegn Mesele Gesese, Yenealem Solomon Kebede, Sefineh Fenta Feleke, Tadesse Asmamaw Dejenie, Natnael Amare Tesfa, Wubet Alebachew Bayih, Ermias Sisay Chanie, Berihun Bantie

“…<h4>Background</h4>Globally, with a neonatal mortality rate of 27/1000 live births, Sub-Saharan Africa has the highest rate in the world and is responsible for 43% of all infant fatalities. In the first week of life, almost three-fourths of neonatal deaths occur and about one million babies died on their first day of life. …”
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Acceptability and efficacy of the culturally adapted problem management plus intervention for people with disability in Pakistan: a pilot cluster randomized controlled trial by Basharat Hussain, Basharat Hussain, Muhammad Tahir Khalily, Muhammad Tahir Khalily, Ahmed Waqas, Atif Rahman, Ioannis Angelakis, Anum Nisar, Sabir Zaman, Tanveer Akhtar

“…The intervention’s effectiveness and participant satisfaction were assessed using a variety of measures, including the GHQ-12, WHODAS 2.0, DASS-21, and the Client Satisfaction Questionnaire, at baseline, the 8th week, and during a 3-month follow-up. Qualitative feedback was gathered at the end of the study to assess the intervention’s acceptability among the participants.ResultsThe study achieved a 100% retention rate. …”
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The newborn behavioural observations (NBO) system embedded in routine postpartum care in at-risk families in Iceland: a randomised controlled trial by Lisbeth Valla, Kari Slinning, Tore Wentzel-Larsen, Gun-Mette Røsand, Stefanía Birna Arnardóttir

“…Maternal confidence was measured using a parent questionnaire (covering learning outcomes relating to the infant’s communicative signals and maternal confidence) administered after each home visit in weeks 2, 3 and 4 postpartum. At 4 months infant age, a free-play situation involving mother-infant interaction was video-recorded in the participants’ homes and coded using the Emotional Availability Scale (EAS). …”
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N-acetylcysteine increased the growth performance of Leuciscus waleckii by improving mitochondrial function, enhancing antioxidant and anti-inflammatory, and inhibiting apoptosis i... by Deng Lai Li, Rui Zhu, Si Tong Meng, Yin Tao Wang, Si Ying Liu, Zhi Yong Yang, Li Fang Wu

“…Diets containing different levels of NAC (0.00 g/kg, 1.50 g/kg, 3.00 g/kg, 4.50 g/kg, 6.00 g/kg) were formulated. An 8-week feeding trial was conducted with these diets. …”
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Hypoglychemic activity of Moringa oleifera extract in streptozotocin-induced diabetic rats by Rabiatul Adawiyah, Tri Setyawati, Rahma Badaruddin, Listawati

“…Method: Healthy male Wistar rats (weight 200-300 g, aged 9-11 weeks) were used in the experiment. The rats were divided into five groups: normal control (healthy), negative control (diabetic without treatment), positive control (diabetic treated with 9 mg/200 g metformin), treatment 1 (diabetic treated with 400 mg/kg BW M. oleifera extract), and treatment 2 (diabetic treated with 800 mg/kg BW M.oleifera extract). …”
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Iron deficiency, supplementation, and sports performance in female athletes: A systematic review by Michael Pengelly, Kate Pumpa, David Bruce Pyne, Naroa Etxebarria

“…Studies were included that evaluated the effects of iron deficiency or FeSup on sports performance in high-level (maximal oxygen uptake (VO2max) > 45 mL/kg/min, or trained > 5 h/week) iron deficient (ID) (serum ferritin (sFer) < 40 µg/L) female athletes. …”
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Effects of the MyBFF@school obesity intervention program with nutrition education intervention on nutrition knowledge and attitude of secondary schoolchildren: a cluster randomized... by Rusidah Selamat, Junidah Raib, Nur Azlina Abdul Aziz, Norlida Zulkafly, Ainan Nasrina Ismail, W Nurul Ashikin W Mohamad, Ainol Aizuddin Zulkiply, Muhammad Yazid Jalaludin, Fuziah Md. Zain, Zahari Ishak, Abqariyah Yahya, Abdul Halim Mokhtar

“…The intervention group was given NEI consisting of a nutrition education module carried out by trained personnel for 24 weeks on top of the existing curriculum while the control group only followed the existing school curriculum by the Ministry of Education. …”
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The Role of Bakau Snail, Telescopium telescopium L., as Biofilter in Waste Water Management of Intensive Shrimp Culture by , Hamsiah, Daniel Djokosetiyanto, E. M. Adiwilaga, Kukuh Nirmala

“…Waste water quality measurement was carried out during a week, while the growth and survival rate were measured during two months.  …”
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A phase Ia study of a novel anti-HER2 antibody–drug conjugate GQ1001 in patients with previously treated HER2 positive advanced solid tumors by Chenfei Zhou, Bin Wang, Christina Teng, Hui Yang, Sarina A. Piha-Paul, Gary Richardson, Ashanya Malalasekera, Yajun Sun, Wei Wang, Jieqiong Liu, Yan Shi, Xianbao Zhan, Charlotte Lemech

“…Eligible patients were enrolled, and GQ1001 monotherapy was administered intravenously every 3 weeks. The starting dose was 1.2 mg/kg, followed by 2.4, 3.6, 4.8, 6.0, 7.2 and 8.4 mg/kg. …”
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Efficacy of Esophageal Protector in Treating Gastroesophageal Reflux Disease with Extraesophageal Symptoms: a Multicenter, Open-Label, Observational Study by Yu. A. Kucheryavy, D. N. Andreyev, E. Yu. Eryomina, A. A. Gilmanov, O. V. Nazarova, Ye. A. Sidneva, Yu. G. Topalova

“…Visit 1 could be conducted on the same day as the screening visit, whereas visit 2 was conducted 4–5 weeks after visit 1 at the end of the course of treatment.Results. …”
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Risk Factors and Pharmacological Interventions Impacting Cerebrovascular Ischemic Events in Giant Cell Arteritis: A Narrative Review by Muhammad Osama Siddiqui, Mohammad Ali Syed, Ayaan Ahmed Qureshi, Mustafa Hussain Imam, Jatin Motwani, Verkha Kumari, Arooba Siddiqui, Noor Ul Ain, Mohammed Hammad Jaber

“…Some studies found that within 2 weeks of GCA diagnosis, 74% and 34% of patients experience transient or severe ischemic events, respectively. …”
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Beta 3 adrenoreceptors protect from hypertrophic remodelling through AMP‐activated protein kinase and autophagy by Emilie Dubois‐Deruy, Roselle Gelinas, Christophe Beauloye, Hrag Esfahani, Lauriane Y.M. Michel, Chantal Dessy, Luc Bertrand, Jean‐Luc Balligand

“…We confirmed results in mice with cardiomyocyte‐specific moderate expression of human β3‐AR (β3‐TG) and wild‐type (WT) littermates submitted to thoracic transverse aortic constriction (TAC) for 9 weeks. We observed a colocalization of β3‐AR with the AMP‐activated protein kinase (AMPK) both in neonatal rat and in adult mouse cardiomyocytes. …”
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OUTCOME OF DEVELOPMENTAL THERAPY IN CHILDREN WITH CEREBRAL PALSY CHILDREN: A PROSPECTIVE COHORT by Erum Afzal, Tanveer Ahmad, Muhammad Khalid Iqbal, Kausar Aftab, Rubeena Muein

“…All the Patients were advised regular weekly sessions at hospital by multidisciplinary team and at least 2 hours per day for continuation of these therapies at home. …”
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