Assessment of Effect of Magnesium Intake on Blood Pressure Control in Hypertensives: A Case-control Study with a Nested Intervention of Flax Seeds Administration to Increase Magnes... by Vidhi Patel, Ashutosh Chauhan, Shubhangi Deshpande, Lalithambigai Arumugasamy, Nishi Patel

“…A subset of 23 patients was given an intervention of three tablespoons of roasted whole flaxseeds daily for 4 weeks, and the significance of the change in mean BP, before and after the intervention, was assessed using a paired <i>t</i>-test. …”
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Maternal and neonatal outcomes of Group B Streptococcus colonization: a retrospective study by Guixiu Jin, Lanhua Liu, Xiaolong Wang, Junling Fei, Zhenling Zhu, Ziyan Jiang, Min Liu

“…Pregnant women between 35 and 37 weeks of gestation had GBS screening using real-time polymerase chain reaction (RT-PCR). …”
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Evaluation of placental growth factor, Vitamin D, and systemic inflammatory index as predictive biomarkers for preeclampsia severity: a retrospective cohort study by Xiaoyan Han, Hua Yang

“…Data on demographic, clinical, and laboratory characteristics, including PlGF, Vitamin D, neutrophil, lymphocyte, and monocyte counts, were collected between 16 and 20 weeks of gestation. Logistic regression analysis was performed to identify independent risk factors, and receiver operating characteristic (ROC) curve analysis was used to assess the predictive power of PlGF, Vitamin D, lymphocyte count, and Pan-immune-inflammation value (PIV). …”
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Early changes of peripheral circulating immune subsets induced by PD-1 inhibitors in patients with advanced malignant melanoma and non-small cell lung cancer by Simona Borilova, Peter Grell, Iveta Selingerova, Lenka Gescheidtova, Marie Mlnarikova, Ondrej Bilek, Radek Lakomy, Alexandr Poprach, Jan Podhorec, Igor Kiss, Rostislav Vyzula, Barbora Vavrusakova, Jiri Nevrlka, Lenka Zdrazilova-Dubska

“…Also, a high Treg count after 2 weeks of ICI treatment was associated with significantly prolonged PFS (p = 0.016, HR 2.33). …”
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A murine model of acute and prolonged abdominal sepsis, supported by intensive care, reveals time-dependent metabolic alterations in the heart by Bart Jacobs, Inge Derese, Sarah Derde, Sarah Vander Perre, Lies Pauwels, Greet Van den Berghe, Jan Gunst, Lies Langouche

“…We hypothesized that metabolic and inflammatory cardiac changes, previously observed in acute sepsis as potential drivers of SICM, partially persist in prolonged sepsis. Methods In 24-week-old C57BL/6J mice, sepsis was induced by cecal ligation and puncture, followed by intravenous fluid resuscitation, subcutaneous analgesics and antibiotics, and, in the prolonged phase, by parenteral nutrition. …”
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Reliability of the Tuck Jump Assessment Using Standardized Rater Training by Kevin Racine, Meghan Warren, Craig Smith, Monica R. Lininger

“…Raters used the online standardized training, scored 41 videos of participants' TJAs, then scored them again two weeks later. Reliability estimates were determined using intraclass correlation coefficients (ICCs) for total scores of 10 technique flaws and Krippendorff α (K α) for the individual technique flaws (ordinal)…”
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Breaking the cycle: a pilot study on autonomous Digital CBTe for recurrent binge eating by Rebecca Murphy, Charandeep Khera, Emma L. Osborne

“…The intervention, called Digital CBTe, comprised 12 sessions over 8–12 weeks delivered autonomously (i.e., without external support). …”
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Pharmacy students’ opinion on mandatory summer internships carried out in community and hospital pharmacies by Lucyna Bułaś, Anna Gołda, Ewa Długosz, Artur Owczarek, Anna Zagaja, Mariola Drozd

“…The first two internships are held after the third and fourth year of study during the summer break and last for four weeks. The study aims to analyze the didactic process of the pharmacy students taking place during the summer internship in community and hospital pharmacies in Poland. …”
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Disentangling the effects of intermittent faecal shedding and imperfect test sensitivity on the microscopy-based detection of gut parasites in stool samples. by Lana C E Ferreira-Sá, Eleuza R Machado, Rodrigo Gurgel-Gonçalves, Fernando Abad-Franch

“…<h4>Methods/findings</h4>We collected 1-3 stool samples, in consecutive weeks, from 276 children. Samples (413 overall) were independently examined, via standard sedimentation/optical microscopy, by a senior parasitologist and a junior, trained student (826 tests overall). …”
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Longitudinal impact of preregistration interprofessional education on the attitudes and skills of health professionals during their early careers: a non-randomised trial with 4-yea... by Ben Darlow, Jennifer Roberts, Patrick McHugh, Melanie Brown, Eileen McKinlay, Peter Gallagher, Lesley Gray, Gordon Purdie, Christine Wilson, Sue Pullon, Louise Beckingsale, Kaye Cheetham, Ruth Crawford, Sue Floyd, Janice Handley, Jackie Herkt, Lisa Kuperus, Alison Meldrum, Margot Skinner, Rose Schwass, Julie Weaver, James Windle, Lyndie Foster-Page

“…Objective To assess whether a preregistration interprofessional education (IPE) programme changed attitudes towards teamwork and team skills during health professionals’ final year of training and first 3 years of professional practice.Design Prospective, longitudinal, non-randomised trial.Setting Final year health professional training at three academic institutions in New Zealand.Participants Students from eight disciplines eligible to attend the IPE programme were recruited (617/730) prior to their final year of training. 130 participants attended the IPE programme; 115 intervention and 372 control participants were included in outcome analysis.Intervention The 5-week Tairāwhiti IPE (TIPE) immersion programme during which students experience clinical placements in interdisciplinary teams, complete collaborative tasks and live together in shared accommodation.Main outcome measures Data were collected via five surveys at 12-month intervals, containing Attitudes Towards Healthcare Teams Scale (ATHCTS), Team Skills Scale (TSS) and free-text items. …”
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Feasibility of a pragmatic randomized adaptive clinical trial to evaluate a brief negotiational interview for harmful and hazardous alcohol use in Moshi, Tanzania. by Catherine A Staton, Kaitlyn Friedman, Ashley J Phillips, Mary Catherine Minnig, Francis M Sakita, Kennedy M Ngowi, Brian Suffoletto, Jon Mark Hirshon, Monica Swahn, Blandina T Mmbaga, Joao Ricardo Nickenig Vissoci

“…<h4>Results</h4>Overall, 181 patients were screened and 75 enrolled with 80% 6-week, 82.7% 3-month and 84% 6-month follow-up rates showing appropriate Reach and retention. …”
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Effects of a periodic intermittent theta burst stimulation in Alzheimer’s disease by Yue Wu, Lu Wang, Kai Wang, Shanshan Zhou, Pan Wu, Yibing Yan, Ling Wei, Bensheng Qiu, Yanghua Tian, Zhi Geng, Xingqi Wu, Panpan Hu, Guixian Xiao, Gongjun Ji, Hesheng Liu

“…However, the long-term effects of iTBS on cognitive decline and brain structure in patients with AD are unknown.Aims We aimed to explore whether repeating accelerated iTBS every three months could slow down the cognitive decline in patients with AD.Methods In this randomised, assessor-blinded, controlled trial, iTBS was administered to the left dorsolateral prefrontal cortex (DLPFC) of 42 patients with AD for 14 days every 13 weeks. Measurements included the Montreal Cognitive Assessment (MoCA), a comprehensive neuropsychological battery, and the grey matter volume (GMV) of the hippocampus. …”
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A new prognostic model for predicting overall survival and progression-free survival in unresectable hepatocellular carcinoma treated with the FOLFOX-HAIC regimen based on patient... by Qiuyao Zeng, Zehong Zhou, Ji Zhang, Rongzeng Cai, Hongwei Yang, Pengfei Chen, Linfang Li

“…Methods This model was based on a retrospective study of u-HCC patients treated with the FOLFOX-HAIC (oxaliplatin 130 mg/m2, leucovorin 400 mg/m2, fluorouracil bolus 400 mg/m2 on day 1, and fluorouracil infusion 2,400 mg/m2 for 23–46 h, once every 3–4 weeks). We divided the patients into a training cohort and a validation cohort, used LASSO regression construct prognostic models, predict patient’s OS and PFS based on nomograms of models. …”
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The Knee-SCHOOL: a brief patient-centered multidisciplinary educational program for knee osteoarthritis by Denise Vianna Machado Ayres, Sabrina Saemy Tome Uchiyama, Andréa Oliveira Prates, Rosana Aparecida Freitas Lopes, Antenor Bispo Santos Silva, Denise Rodrigues Tsukimoto, Rosimeire Alves Amorim, Taynah Souza Ribeiro, Artur Cesar Aquino Santos, André Tadeu Sugawara, André Tadeu Sugawara, Marcos Montagnini, Linamara Rizzo Battistella, Linamara Rizzo Battistella, Marta Imamura, Marta Imamura

“…The mean pain intensity, measured with visual analogue scale, score reduced from 5.52 (± 2.11) at baseline to 4.04 (± 2.38) after the program (week 2). The effect size was 0.7 (95% CI 0.32 to 1.07). …”
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A brief instrument measuring the water, sanitation and hygiene domain of menstrual health among women who inject drugs. by Alhelí Calderón-Villarreal, Lourdes Johanna Avelar Portillo, Daniela Abramovitz, Shira Goldenberg, Shawn Flanigan, Penelope J E Quintana, Alicia Harvey-Vera, Carlos F Vera, Gudelia Rangel, Steffanie A Strathdee, Georgia L Kayser

“…<h4>Methods</h4>We constructed a MH-scale based on access to twelve WASH-related items: (1) menstrual products, (2) body hygiene (bathing per week), (3) water sources for bathing, (4) improved, (5) non-shared, (6) available, (7) private, (8) nearby, (9) and safe sanitation facilities, (10) availability of soap, (11) water source for handwashing, and (12) handwashing facilities with soap/water. …”
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Risk factors associated with the failure of local methotrexate combined with minimally invasive surgery for late cesarean scar pregnancy by Xiao-Tong Cheng, Yan-Song Liu, Dan-Yang Song, Xiao-Cui Nie, Yu-Shi Xiang, Ju-Min Niu

“…Methods This retrospective case-control study was conducted between January 2016 and December 2023, involving patients with late CSP (≥ 8 weeks) who received local MTX injection combined with either hysteroscopic or laparoscopic surgery. …”
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Oral Opportunistic Infection Induced by Stress and Silent Type 2 Diabetes Mellitus in Young Adult Patient: A Case Report by Karina D, Heldayani I, Hidayat W

“…Non-pharmacologic therapy dental included oral hygiene instruction and education on oral therapy and referral to the internal medicine clinic for DM management. After two weeks of collaborative treatment between oral medicine and internal medicine, there was significant improvement.Conclusion: Silent type 2 DM and stress can cause a decrease in the immune system, triggering opportunistic infections, namely RIH and candidiasis.Keywords: diabetes mellitus, immunosuppression, oral opportunistic infections, stress…”
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Nobiletin Attenuates Pathological Cardiac Remodeling after Myocardial Infarction via Activating PPARγ and PGC1α by Yufei Zhou, Ting Yin, Mengsha Shi, Mengli Chen, Xiaodong Wu, Kai Wang, Iokfai Cheang, Yanxiu Li, Hongcai Shang, Haifeng Zhang, Xinli Li

“…C57BL/6 mice were treated with coronary artery ligation to generate an MI model, followed by treatment for 3 weeks with NOB (50 mg/kg/d) or vehicle (50 mg/kg/d), with or without the peroxisome proliferator-activated receptor gamma (PPARγ) inhibitor T0070907 (1 mg/kg/d). …”
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Efficacy Study of Carrageenan as an Alternative Infused Material (Filler) in Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) Porous 3D Scaffold by Nor Syamimi Che Johari, Syazwan Aizad, Saiful Irwan Zubairi

“…The carrageenan infused scaffold of 4% (w/v) was demonstrated to be the best 3D structure for a long-term cell culture (>2 weeks). In conclusion, the usage of carrageenan as a composite material exhibits its great potential to be used in tissue engineering application and 3D cell culture model.…”
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Wavefront-guided pupilloplasty in patients following penetrating keratoplasty: Optimizing results by Vijay K Sharma, GN Divyashree, Preeti, Vikas Ambiya, Ashok Kumar, Srishti Khullar, Vipin Rana

“…Patients showing significant improvement between preoperative and predicted postoperative wavefront values underwent single-pass four-throw pupilloplasty, and all wavefront parameters were again evaluated after 1 week. Preoperative and postoperative best corrected visual acuity (BCVA), pupil size, and wavefront parameters were analyzed. …”
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