The kinetics of maternal and self-developed Streptococcus suis-specific antibodies by Sandra Vreman, Rutger Jansen, Mikael Bastian, Patricia Beckers, Miriam van Riet, Helmi Fijten, Jan Fledderus, Astrid de Greeff, Hélène Winkelman, Norbert Stockhofe-Zurwieden, Lluís Fabà, Henk J. Wisselink, Manouk Vrieling

“…Subsequently, study II used one of these farms to evaluate S. suis-specific and total antibody kinetics in piglets (10 litters with 6 selected piglets per litter, total n = 60) from birth until 10 weeks of age. Additionally, tonsil swabs from sows and piglets were taken to evaluate the S. suis tonsillar carrier status (serotypes 2 and 9) before and after weaning. …”
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Phase Ib/II study on the safety, tolerability, and preliminary efficacy of pegylated irinotecan (JK1201I) as second‐line monotherapy for patients with small‐cell lung cancer by Jieran Long, Xuefei Li, Lin Wu, Guohua Yu, Aimin Zang, Yanqiu Zhao, Jinsheng Shi, Ligong Nie, Xuan Zhao, Jian Fang

“…Methods According to the “3 + 3” dose‐escalation principle, patients received intravenous JK1201I at 180 or 220 mg/m2 once every 3 weeks for four cycles. Progression‐free survival (PFS), overall survival (OS), median progression‐free survival (mPFS), and median overall survival (mOS) were evaluated. …”
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Development of single-pin, un-barbed, pole-tagging of free-swimming dolphins and sharks with satellite-linked transmitters by Michael J. Moore, Thomas M. Lanagan, Randall S. Wells, Jason Kapit, Aaron A. Barleycorn, Jason B. Allen, Robin W. Baird, Camrin D. Braun, Gregory B. Skomal, Simon R. Thorrold

“…It was developed using fins from cadavers, then trialed on briefly restrained coastal dolphins that could be followed in successive days and weeks, and then on free-swimming animals in the field. …”
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The impact of arbuscular mycorrhizal colonization on flooding response of Medicago truncatula by Vajiheh Safavi-Rizi, Vajiheh Safavi-Rizi, Helen Friedlein, Sayedhamid Safavi-Rizi, Franziska Krajinski-Barth

“…In this study, we investigated the effects of mycorrhizal colonization and flooding stress on the growth, physiological and molecular responses of M. truncatula wild-type (WT) and ha1-2 mutant lines. ha1-2 mutant plants are unable to form a functional symbiosis with AM fungi as they are impaired in the proton pump required for phosphate transport from AM fungus to the plant. Over a six-week period, WT and ha1-2 plants were cultivated in the presence of Rhizophagus irregularis and subsequently subjected to a 10-day waterlogging treatment. …”
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Response of Differently Structured Dental Polymer-Based Composites to Increasingly Aggressive Aging Conditions by Nicoleta Ilie

“…Specimens (308) were either cut from CAD/CAM blocks (VE/BC) or condensed and cured in white polyoxymethylene molds (AF5) and subjected to four different aging conditions (<i>n</i> = 22): (a) 24 h storage in distilled water at 37 °C; (b) 24 h storage in distilled water at 37 °C followed by thermal cycling for 10,000 cycles 5/55 °C (TC); (c) TC followed by storage in a 75% ethanol–water solution; and (d) TC followed by a 3-week demineralization/remineralization cycling. CAD/CAM samples were also measured dry before the aging process. …”
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Obesity-induced mesenteric PVAT remodelling is sexually dimorphic, but not driven by ovarian hormones by Lisa Ivatt, Mhairi Paul, Allende Miguelez-Crespo, Patrick W. F. Hadoke, Matthew A. Bailey, Ruth A. Morgan, Mark Nixon

“…Methods Adult male and female C57Bl/6J mice were fed an obesogenic high-fat diet (HFD) or regular chow for 16 weeks. Mesenteric PVAT (mPVAT) was isolated for RNA-sequencing and histological analysis, and mesenteric arteries were isolated for assessment of vascular function by wire myography. …”
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Longitudinal Changes of Sensorimotor Resting-State Functional Connectivity Differentiate between Patients with Thalamic Infarction and Pontine Infarction by Peipei Wang, Zhenxiang Zang, Miao Zhang, Yanxiang Cao, Zhilian Zhao, Yi Shan, Qingfeng Ma, Jie Lu

“…Fourteen patients with unilateral infarction of the thalamus and 14 patients with unilateral infarction of the pons underwent longitudinal fMRI measurements and motor functional assessment five times during a 6-month period (<7 days, at 2 weeks, 1 month, 3 months, and 6 months after stroke onset). …”
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Long-Term Safety and Effectiveness of Dimethyl Fumarate in Patients with Multiple Sclerosis Treated in Routine Medical Practice: Final Analysis of the ESTEEM Study by Krupa Shah Pandey, Kathryn Giles, Konstantin Balashov, Richard Macdonell, Jörg Windsheimer, Mikel Martinez, Ivan Božin, Stephanie Raynaud, Matthew Scaramozza, Oksana Mokliatchouk, Zhaonan Sun, Nicholas Belviso, Yayoi Sato, Xiaochen Lin, Annette Okai

“…The estimated proportion of patients free from confirmed disability progression sustained over 48 weeks was 87.0% at month 60. Mean scores for physical and psychological impact, fatigue, health, and productivity remained stable over 5 years. …”
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Huerto urbano Adelfas (Madrid, 24 de enero de 2021) by Claudia Antón Biezma

“…It is a big space, it gets sun light, neighbours water it twice per week and it is open to everyone. The main advantage of this type of garden is for city kids to be able to be in contact with something rural, where they can plant and grow vegetables. …”
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Reliability of the Expanded Cutting Alignment Scoring Tool (E-CAST) to Assess Trunk and Limb Alignment During a 45-Degree Side-Step Cut by Lauren S. Butler, Alexa R. Martinez, Dai Sugimoto, Charles W. Wyatt, Eryn K. Milian, Sophia Ulman, Ashley Erdman, Alex Loewen, Kristin Hayden, Amie DeVerna, Kirsten Tulchin-Francis, PRiSM Injury Prevention Research Interest Group

“…Two physical therapists independently scored each video using the E-CAST on two separate occasions, with randomization and a two-week wash-out between rounds. Observed movement variables were awarded a score of “1”, with higher scores representing poorer technique. …”
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Single-Cell RNA Sequencing Analysis of Steroidogenesis and Spermatogenesis Impairment in the Testis of db/db Mice by Yun Hu, Ting-Ting Cai, Reng-Na Yan, Bing-Li Liu, Bo Ding, Jian-Hua Ma

“…The histopathological characteristics of testis in db/db mice and C57BL/6J control were also performed. Results. The 20-week-old db/db mice had significantly higher blood glucose and body weight (both p<0.001). …”
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Day-to-day dynamics of fetal heart rate variability to detect chorioamnionitis in preterm premature rupture of membranes. by Aline Taoum, Guy Carrault, Caroline Tesson, Maxime Esvan, Bruno Laviolle, Linda Lassel

“…<h4>Materials & methods</h4>120 pregnant women with PPROM between 26 and 34 weeks' gestation were enrolled in this multicenter prospective unblinded study. …”
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Cardiomyopathy and kidney function in agalsidase beta‐treated female Fabry patients: a pre‐treatment vs. post‐treatment analysis by Christoph Wanner, Ulla Feldt‐Rasmussen, Ana Jovanovic, Aleš Linhart, Meng Yang, Elvira Ponce, Eva Brand, Dominique P. Germain, Derralynn A. Hughes, John L. Jefferies, Ana Maria Martins, Albina Nowak, Bojan Vujkovac, Frank Weidemann, Michael L. West, Alberto Ortiz

“…Methods and results Self‐controlled pretreatment and post‐treatment comparison (piecewise mixed linear modelling) included Fabry female patients ≥18 years at treatment initiation who received agalsidase beta (0.9–1.1 mg/kg every other week) for ≥2 years, with ≥2 pretreatment and ≥2 post‐treatment outcome measurements during 10‐year follow‐up. …”
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L’abdication du Congrès après le 11 septembre : crise constitutionnelle ou politique ? by Maya KANDEL

“…With other methods, vice-president Dick Cheney, the chief artisan of this expansion of the president’s powers, was particularly skillful in taming Congress by his stranglehold on Republican lawmakers – and most notably his attendance at the Republican Caucus’ weekly strategy sessions on Capitol Hill.All this has led many commentators to speak of a constitutional crisis and of an executive branch less accountable than at any time in modern American history.The depth of Congress’ deference certainly reflected the enormity of the attacks, the belief that lawmakers should defer to strong presidential leadership in times of national crisis, and a conscious and thorough effort on the part of some of President Bush’s closest advisers. …”
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Does Sex Matter in Obesity-Induced Periodontal Inflammation in the SS^LepR Mutant Rats? by Abdulmohsin Alhashim, Kim Capehart, Jocelyn Tang, Karim M. Saad, Rafik Abdelsayed, Marion A. Cooley, Jan M. Williams, Ahmed A. Elmarakby

“…<b>Methodology:</b> Utilizing leptin receptor mutant (SS^LepR mutant) rats as a genetic model of obesity, 11–12-week-old male and female lean Dahl salt-sensitive (SS) rats and obese SS^LepR mutant rats were used to investigate sex differences in obesity-induced periodontal inflammation. …”
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Estimating avoidable burden of stillbirth attributable to greenness improvement in Iran by Yang Yuan, Fatemeh Mayvaneh, Yaqi Wang, Jixing Yang, Yunquan Zhang, Fang Shi

“…Stillbirth was defined as the birth of babies with no signs of life at ≥22 weeks of gestation. Multivariable-adjusted logistic regression models were employed to investigate greenness-stillbirth associations. …”
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Derivation of a simple risk calculator for predicting clinical worsening in patients with pulmonary hypertension due to interstitial lung disease by K. El-Kersh, R. Bag, N. Bhatt, C. King, A. Waxman, F. Rischard, H. Kim, D. Cella, E. Shen, SD Nathan

“…Methods: The INCREASE study was a 16-week study that evaluated inhaled treprostinil in patients with ILD-PH. …”
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Dynamic Impact of the Sleep Disorder, Depression and Anxiety on the Cognitive Function in the First-Episode Depressive Patients by Zhang W, Zhou N, Li J

“…Three visits were set at baseline at the 4th and the 8th weeks. Latent Growth Curve Models (LGCM) were used to analyze the changing tendency and correlation between sleep disorder, depression, anxiety status, and cognitive function in patients with MDD.Results: Baseline sleep status in patients with MDD could predict cognitive function (p=0.043) and changes in cognitive function (p=0.016), and changes in depressive symptoms could negatively predict cognitive function (p=0.021). …”
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Dietary Alpha-Lipoic Acid Alleviated Hepatic Glycogen Deposition and Improved Inflammation Response of Largemouth Bass (<i>Micropterus salmoides</i>) Fed on High Dietary Carbohydra... by Zishuo Fang, Xianwei Pan, Ye Gong, Nihe Zhang, Shiwen Chen, Ning Liu, Naisong Chen, Songlin Li

“…Three iso-nitrogenous and iso-lipidic diets supplementing with 0 g/kg, 0.5 g/kg and 1 g/kg LA (LA0, LA500, LA1000) were designed to feed juvenile largemouth bass on a satiation diet twice daily for eight weeks with each diet feeding to triplicate groups. …”
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Mechanistic investigation and the optimal dose based on baicalin in the treatment of ulcerative colitis–A preclinical systematic review and meta-analysis by Jinchen Chong, Zepeng Chen, Jiaze Ma, Linhai He, Yijia Zhu, Zhihua Lu, Zhengxi Qiu, Chen Chen, Yugen Chen, Feng Jiang

“…Optimal therapeutic outcomes were predicted at dosages of 60–150 mg/kg over 10–14 weeks. Conclusion Baicalin demonstrates a multifaceted therapeutic potential in UC, attributed to its anti-inflammatory, antioxidant, anti-apoptotic, and intestinal barrier repair properties. …”
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