Impact of glucocorticoids on the therapeutic efficacy of denosumab against osteoporosis in patients with rheumatoid arthritis by Jiwon Yang, Youngjae Park, Jennifer Jooha Lee, Seung-Ki Kwok, Ji Hyeon Ju, Wan-Uk Kim, Sung-Hwan Park

“…Objectives: In this study, we aimed to evaluate the therapeutic efficacy of denosumab according to the GC dose considered to increase the risk of glucocorticoid-induced osteoporosis (GIOP) in patients with RA. …”
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Associations of linear growth and weight gain in the first 2 years with bone mass at 4 years of age in children in Dhaka, Bangladesh by Maimuna Gias, Huma Qamar, Farzana Fariha, Abdullah Al Mahmud, Prakesh Shah, Steven A Abrams, Daniel E Roth, Karen M O’Callaghan

“…Results: cLAZ in each age interval was positively associated with TBLH BMC, aBMD and bone area at 4 years; however, associations attenuated towards null upon adjustment for concurrent height-for-age z-scores (HAZ) at age 4 years and confounders. cWAZ from 0 to 6 and 6 to 12 months was not associated with bone mass, but every sd increase in cWAZ between 12 and 24 months was associated with greater BMC (7·6 g; 95 % CI: 3·2, 12·0) and aBMD (0·008 g/cm2; 95 % CI: 0·003, 0·014) after adjusting for concurrent WAZ, HAZ and confounders. …”
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Clinical management of community-acquired meningitis in adults in the UK and Ireland in 2017: a retrospective cohort study on behalf of the National Infection Trainees Collaborativ... by Amy Robinson, Kamaljit Khalsa, Arjun Chandna, John Bowen, Viva Levee, Jan Coebergh, Tom Solomon, Clive Graham, David Turner, Robert Tilley, Tim Jones, Susan Hopkins, Matthew Stevens, Daniel White, Celestine Eshiwe, Anna Goodman, Ramandeep Singh, Robert S Heyderman, Nicholas Davies, Joseph Thompson, Ed Moran, Martin Williams, Rhea O’Regan, Simon Tiberi, Jonathan Lambourne, Naomi Bulteel, Susan Larkin, Ruth McEwen, Hassan Paraiso, Aarti Shah, Martin Wiselka, Sylviane Defres, Ernest Mutengesa, Maria Krutikov, Ruth Owen, David Griffith, David Harvey, Trupti Patel, Brendan Davies, Emma Mclean, Joanna Allen, Ali Khan, Alastair Miller, Ashutosh Deshpande, Christopher Green, Lewis Jones, Mark Melzer, Fiona McGill, Amanda Fife, Nimal Wickramasinghe, Stephanie Harris, Ewan Hunter, Jayne Ellis, Benedict Rogers, Imogen Fordham, Elen Vink, Victoria Ward, Anna Smith, Andrew Rosser, Alison Muir, Ken Woodhouse, John Shone, Iain Crossingham, Ryan Jayesinghe, Eavan Muldoon, Avneet Shahi, Terry John Evans, Jeremy Wong, Eloisa MacLachlan, Amy Chue, Karishma Gokani, Katherine Ajdukiewicz, Lucinda Barrett, Frances Edwards, Adam Usher, Mairi McLeod, Su su Htwe, Grace Duane, Nicholas Wong, Jennifer Poyner, Jenni Crane, Ollie Lloyd, Emma Chisholm, Ildiko Kustos, Sam Sutton, M. Estee Torok, Isobel Ramsay, Monica Ivan, Joshua York, Jennifer Ansett, Maithili Varadarajan, Priya Sekhon, James Cruise, Shivani Kanabar, Mirella Ling, Charlotte Milne, Jayanta Sarma, Aline Wilson, Lynn Urquhart, Sahar Eldirdiri, Leila White, Jody Aberdein, Phillip Simpson, Hnin Hay Mar, Keying Tan, Eint Shwe Zin thein, Mahmoud Aziz, Anthony Cadwgan, Natasha Weston, Salman Zeb, Angela Houston, Louise Wootton, Iona Willingham, Aimee Johnson, Ashley Horsley, Eamonn Trainor, Olivier Gaillemin, Nicholas J Norton, Katie Cheung, Megan Duxbury, Emilie Bellhouse, Helena Brezovjakova, Kanitkar Tanmay, Alexsander Dawidziuk, Razan Saman, Hugh Adler, Elshadai Ejere, Yiwen Soo, Wendy Beadles, Heather Sturgeon, Brodie Cameron, David Chadwick Ben Tomlinson, Claire McGoldrick, Katie McDowell, Mpho Molosiwa, Katherine FlackAdrian Kennedy, Phoebe Cross, Fay Perry, Vithusha Inpadhas, Sarathy Selvam, Vhairi Bateman, Henry Wu, Monika Pasztor, Ajanthiha Karunakaran, Basma Soliman, Andrew Blanshard, Harish Reddy, Helen Chesterfield, Ben Schroeder, Tee Keat Teoh, Sathyavani Subbarao, Caryn RosmarinLucy Bell, Emma McGuire, Robert Serafino, Ishaan Bhide, Karanjeet Sagoo, Indran Balakrishnan, Kajal Patel, Barzo Faris, Graeme Calver, Ricky Singh, Hazel Sanghvi, Mohamed Eltayeb, Rathur Haris

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EFT of interacting spin-2 fields by Lasma Alberte, Claudia de Rham, Arshia Momeni, Justinas Rumbutis, Andrew J. Tolley

“…Performing a decoupling and ADM analysis, we point out the existence of a ghost present at a low scale for the first class of interactions. …”
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Type 1 Diabetes (T1D) and Latent Autoimmune Diabetes in Adults (LADA): The Difference Between a Honeymoon and a Holiday by Livia M. R. Marcon, Carmine G. Fanelli, Riccardo Calafiore

“…A subtype of autoimmune diabetes mellitus (ADM) that typically occurs in adulthood is often referred to as latent autoimmune diabetes of adults (LADA). …”
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An Eco-Driving Advisory System for Continuous Signalized Intersections by Vehicular Ad Hoc Network by Wei-Hsun Lee, Jiang-Yi Li

“…With the vehicular ad hoc network (VANET) technology which support vehicle-to-vehicle (V2V) and vehicle to road side unit (V2R/R2V) communications, vehicles can preview the intersection signal plan such as signal countdown message. …”
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Hybrid technique for multi-dimensional fractional diffusion problems involving Caputo–Fabrizio derivative by Surendar Kumar Yadav, Mridula Purohit, Murli Manohar Gour, Lokesh Kumar Yadav, Manvendra Narayan Mishra

“…The proposed approach combines the Shehu transformation (ST) with the Adomian decomposition method (ADM), employing Adomain polynomials to handle nonlinear terms. …”
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Thiazolo-pyridopyrimidines: An in silico evaluation as a lead for CDK4/6 inhibition, synthesis and cytotoxicity screening against breast cancer cell lines by Chaithra R Shetty, C. S. Shastry, Parasuraman P, Srinivas Hebbar

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Druggability and molecular docking of essential secondary metabolites from Azadirachta indica leaf against angiotensin converting enzyme-2: Covid-19 in focus by Paul Chijioke Ozioko, Ukamaka Owohetete, Daniel Danladi Gaiya

“…The in-silico druggability and molecular docking experiments were performed using SwissADME and ADMETlab tools, and Autodock vina and UCSF Chimera respectively. …”
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Synthesis and in silico ADMET evaluation of new thiazole and thiazolidine-4-one derivatives as non-ulcerogenic analgesic and anti-inflammatory agents by Nassiri Koopaei Mansur, Monavari Mahshid, Vousooghi Nasim, Moshirabadi Sadaf, Assarzadeh Mohammad Javad, Amini Mohsen, Almasirad Ali

“…The target compounds showed an acceptable in silico ADME profile.…”
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Exploring purine analogues as inhibitors against Katanin, a microtubule severing enzyme using molecular modeling approach by Vibhuti Saxena, Pruthanka Patil, Purva Khodke, Bajarang Vasant Kumbhar

“…A total of 276,280 purine-type compounds from the PubChem database were subjected to structure-based high-throughput virtual screening, followed by ADME prediction, PASS analysis, and molecular docking studies. …”
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Microbial-based natural products as potential inhibitors targeting DNA gyrase B of Mycobacterium tuberculosis: an in silico study by Tilal Elsaman, Magdi Awadalla Mohamed, Malik Suliman Mohamed, Eyman Mohamed Eltayib, Abualgasim Elgaili Abdalla

“…Following this, computational filters, including ADME-T profiling and pharmacophore modeling, were applied to further refine the selection. …”
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Imperialismo e guerra civil no mundo árabe: a tragédia síria: aporias e consequências da falta de intervir by Peter Demant

“…Paradoxalmente o uso de ADMs do regime de Assad contra civis sírios sepultou a possibilidade de uma intervenção internacional e acabou enfraquecendo as forças democráticas e/ou liberais a favor dos interesses do eixo xiita e de jihadistas sunitas. …”
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Flavouring group evaluation 418 (FGE. 418): 3‐[3‐(2‐isopropyl‐5‐methyl‐cyclohexyl)‐ureido]‐butyric acid ethyl ester by EFSA Panel on Food Additives and Flavourings (FAF), Laurence Castle, Monica Andreassen, Gabriele Aquilina, Maria Bastos, Polly Boon, Biagio Fallico, Reginald FitzGerald, Maria Jose Frutos Fernandez, Bettina Grasl‐Kraupp, Ursula Gundert‐Remy, Rainer Gürtler, Eric Houdeau, Marcin Kurek, Henriqueta Louro, Patricia Morales, Sabina Passamonti, Romualdo Benigni, Kevin Chipman, Eugenia Cordelli, Gisela Degen, Karl‐Heinz Engel, Paul Fowler, Maria Carfí, Gabriele Gagliardi, Agnieszka Mech, Salvatore Multari, Carla Martino

“…The chronic dietary exposure to [FL‐no: 16.136] estimated using the added portions exposure technique (APET) is calculated to be 860 μg/person per day for a 60‐kg adult and 540 μg/person per day for a 15‐kg 3‐year‐old child. …”
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Essential oils from Amorpha fruticosa against hepatocellular carcinoma based on network pharmacology by Yixian Liu, Xiaojun Zhang, Jiacong Hao, Ying Zhao, Min Zou, Huiping Chen, Jintao Zhang

“…The detected components of AFLEO and AFFEO were performed ADME screening to examine their drug-likeness. Then a PPI network, compound-target network, compound-target-pathway network, gene ontology, and KEGG enrichment for HCC were applied to identify the targets and pathways for AFLEO and AFFEO against HCC. …”
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A real–time distributed optimization control for power sharing and voltage restoration in inverter–based microgrids by Asad Khan, Muhammad Mansoor Khan, Jiang Chuanwen, Danish Khan

“…Compared to existing segregation methods like Alternating Direction Method of Multipliers (ADMM) and Augmented Lagrangian Alternating Direction Inexact Newton (ALADIN) schemes, which segregate the network into complex sub–networks involving several GFM sources, the proposed approach is more suitable for small–scale inverter–based MGs. …”
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Muscle-Bone Interactions in Chinese Men and Women Aged 18–35 Years by Meihua Su, Zhaojing Chen, Breanne Baker, Samuel Buchanan, Debra Bemben, Michael Bemben

“…Significant sex differences p<0.05 were found for most body composition variables, hip aBMD, tibia variables, and muscle strength and power. …”
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Effects of desulfurized gypsum on shrinkage behavior of alkali-activated slag (AAS) and hybrid alkali-activated cement (HAC) by Lili Xue, Zhenkun Ni, Zhengning Zhou, Zuhua Zhang, Houren Xiong, Hao Wang, Xifeng Zhuge, Hongfei Liu

“…This study reports the use of desulfurized gypsum (DSG) to mitigate the shrinkage problem of two typical alkali-activated materials (AAMs), i.e. alkali-activated slag (AAS) and hybrid alkali-activated cement (HAC). …”
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Bacteriological valuations of some powdered infant milk and antibiotic resistance estimation by Sameira S. Swilaiman, Lawin A. Omer, Suhaila N. Darogha

“…In addition, Staphylococcus sp. resistance against AMC and E was between (72-69%) and the lowest resistance was against AMK and TE (25-28%). …”
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Synthesis and characterization of Co-W alloy coatings for enhanced hydrogen evolution: effects of bath composition and deposition parameters by A. Chitharanjan Hegde, Meghana K. Navada, Ganesha Aroor, Akshatha R. Shetty

“…The study identified that the Co-W coating prepared using a 0.35 M solution at a current density of 1 Adm2 demonstrated the highest electrocatalytic efficiency. …”
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