Effectiveness of dolutegravir-based vs boosted darunavir-based first-line 3-drug regimens in people with HIV with advanced disease: A trial emulation by Roberta Gagliardini, Andrea Giacomelli, Cristina Mussini, Stephen R. Cole, Jessie K. Edwards, Carmela Pinnetti, Alessandro Raimondi, Spinello Antinori, Silvia Nozza, Valentina Mazzotta, Giulia Carla Marchetti, Sergio Lo Caputo, Alessandro Tavelli, Antonella d'Arminio Monforte, Andrea Antinori, Alessandro Cozzi-Lepri

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Mechanisms of immune regulation and transplantation immunity in corneal transplants by V. V. Neroev, N. V. Balatskaya, E. V. Chentsova, Kh. M. Shamkhalova

“…Unlike other kinds of transplants, corneal grafting is often performed without tissue typing and systemic immunosuppression.High frequency of transparent corneal engraftment (up to 90% of cases) in the absence of risk factors is due to special immunoprivileged area in the anterior eye segment (functionally, a structural aggregation of the cornea and anterior chamber, AC) accomplished by local and systemic immunoregulatory mechanisms, i.e., phenomenon of immune deviation associated with anterior chamber of the eye (ACAID), components of the internal liquid medium, a watery moisture with immunosuppressive properties, e.g., IL-1ra, TSP-1,TGF-β2, regulatory complement proteins, α-MSH (alpha-melanocyte stimulating hormone), VIP (vasoactive intestinal peptide), indolamine 2,3-dioxygenase (IDO), calcitonin-gene-bound peptide (CGRP), somatostatin, etc.In addition to ACAID and liquid AC components, a contribution to the maintenance of immune privilege which is extremely important for a successful outcome of keratoplasty, is provided by other mechanisms, in particular, immunologically active membrane-associated molecules of corneal endothelium, i.e., PDL-1 (Programmed death ligand 1), and sVEGFR-1, sVEGFR-2, sVEGFR-3 involved in maintaining avascularity of the corneal tissue. …”
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Exploring Human-centered AI Literacy Education: Interpretation and Insights from UNESCO's AI Competency Framework for Teachers and Students by Dan WU, Xinjue SUN

“…It analyzes the content of both the AI CFS and the AI CFT, focusing on key principles and framework structure to systematically interpret the framework's content. …”
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The effect of rTMS intervention with different targets on neural remodeling in stroke patients: a randomized controlled trial by Li Zhao, Li Chen, Qiu Wang, Xinyi Li, Sha Li, Chunxiao Wan

“…In order to develop a clinical precision rehabilitation program, this study aims to explore the effects of rTMS at different targets on neural remodeling in patients with subcortical stroke by combining motor function assessment, multimodal MRI and electrophysiological methods.Methods69 stroke patients were randomly assigned to the sham group, M1 group, and SMA group. …”
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Development of a Method for Obtaining Nanoscale Magnesium Carbonate Stabilized with Chitosan as the Basis of Scaffold Matrices for Regenerative Medicine by A. V. Blinov, Z. A. Rekhman, A. A. Gvozdenko, M. A. Yasnaya, M. A. Kolodkin, M. A. Taravanov

“…The creation of three-dimensional matrices based on scaffolds for the formation of systems that are as close as possible to bone tissue in structure has been studied. It is known that the active substances of the scaffold matrix can be hydroxyapatite, tricalcium phosphate, as well as silicates, carbonates of magnesium, calcium, copper, zinc, and manganese. …”
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Emergence and evolution of rare ST592 blaNDM-1-positive carbapenem-resistant hypervirulent Klebsiella pneumoniae in China by Huan Zhang, Su Dong, Caiping Mao, Yuejuan Fang, Junjie Ying

“…Conjugation-related elements were predicted using oriTfinder. The plasmid structure was visualized using Circos, and a possible evolutionary model was constructed using BioRender.ResultsIsolates KPZM6 and KPZM16 were identified as ST592 and KL57, respectively, and were collected from the same department. …”
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Prognostic role of demographic indicators and Charlson comorbidity index in oxygen-dependent patients with coronavirus disease (COVID-19) by V. V. Cherkaskyi, O. V. Riabokon, Yu. Yu. Riabokon

“…We used the WHO age classification when analyzing the age structure of patients. The Charlson comorbidity index was calculated for each patient. …”
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Maternal and gestational factors associated with congenital anomalies among live births: a nationwide population-based study in Brazil from 2012 to 2020 by Qeren Hapuk Rodrigues Ferreira Fernandes, Enny S. Paixão, Maria da Conceição Nascimento Costa, Maria Glória Teixeira, Mauricio Lima Barreto, Angelina Xavier Acosta

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PYMES: Ciclo de Vida y Etapas de su Desarrollo by Juan Carlos Leiva Bonilla

“…*Human Resources Roll. *Structure.Systems (operational and managerial). *Financial and Sales indicators. …”
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Special Features of a 24-hour Arterial Blood Pressure Profile in Healthy Children During the Period of Adaptation to Studying at Different School Types by I. N. Zakharova, T. M. Tvorogova, I. I. Pshenichnikova, M. A. Shkolnikova

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Continuum of care for maternal and newborn health services in Nepal: An analysis from demographic and health survey 2022. by Achyut Raj Pandey, Bikram Adhikari, Raj Kumar Sangroula, Parash Mani Sapkota, Shophika Regmi, Shreeman Sharma, Bishnu Dulal, Bipul Lamichhane, Saugat Pratap Kc, Pratistha Dhakal, Sushil Chandra Baral

“…Nepal's transition to a federal structure with 7 provinces and 753 local governments with decision making authority presents an opportunity to test and scale up innovative strategies for improving continuum of care coverage.…”
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Experience in Using Assessment Tools and e-Learning Quality Management Practices (Case Study of Tomsk State University) by E. S. Goryunova, A. S. Ivanova, A. A. Stepanenko, A. V. Feshchenko

“…The developed tools make it possible to manage the quality of e-learning based on data, and reach the management of the quality of education as a whole through the “balancing” of the structure and content of all components of the educational program.Conclusion. …”
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Mathematical model of a lightweight three-axle off-road vehicle construction for Arctic zone of Russia by I. E. Agureev, V. N. Bondarenko

“…From a mathematical point of view, these equations are classified as second-order ordinary differential equations with a variable structure of the right-hand sides, which reflects the non-linear nature of the behavior of the suspension in terms of its geometric constraints.Methods. …”
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Quantitative Methods of Selecting a Tool for Project Management in the Financial Sector by D. A. Vlasov, P. A. Karasev, A. V. Sinchukov

“…The described structure of the applied problem of multi-criteria selection can be used to update the content of such professionally significant academic disciplines for higher economic school as “Decision Theory” and “Instrumental methods in Economics”.…”
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Dehydrotanshinone II A alleviates osteoarthritis via activating PPARγ to inhibit ferroptosis in chondrocytes by Wenli Guan, Fahu Yuan, Xin Wang

“…Ferroptosis, an iron-dependent form of programmed cell death, has been implicated as a crucial contributor to OA progression. …”
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EDUCATIONAL TOURISM AS A BASIS FOR THE GROWTH OF ECONOMIC ACTIVITY OF THE LABOR MARKET by Olesia Iastremska

“…Theoretical and practical analysis of the work of specialists in the field of educational tourism and the functioning of the labor market has proved the need to use such research methods: monographic, analysis and synthesis, structural-logical method, systematic approach, theoretical generalization. …”
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Economic damage of risk factors associated with morbidity and mortality from major chronic non-communicable diseases in Russia in 2016 by A. V. Kontsevaya, D. K. Mukaneeva, A. O. Myrzamatova, Yu. A. Balanova, M. B. Khudyakov, O. M. Drapkina

“…Indirect losses due to premature mortality prevail over direct costs of medical care and disability benefits in the economic damage structure of each RF. The largest damage of four major CNCDs was associated with HTN — 869,9 billion rubles, which is equivalent to 1,01% of gross domestic product (GDP). …”
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General Cultural Competence of a Future Teacher in a Changing World by O. R. Neradovskaya, V. A. Starodubtsev

“…The results prove that the phenomenon of culture arises in the process of human coevolution. In this study, the structure and content of culture is seen as a sphere with three poles (religion, art, science). …”
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INDIVIDUAL STYLE OF PROFESSIONAL ACTIVITY OF FUTURE PSYCHOLOGISTS: ESSENCE AND WAYS OF FORMATION IN THE EDUCATIONAL PROCESS OF A HIGHER EDUCATION INSTITUTION by Volkova Nataliia, Bykova Viktoriia

“…The content of the individual style of future psychologists’ professional activity includes motivational-value (a system of motives, and value attitudes); cognitive (a set of knowledge about the essence and structure of the individual style of professional activity of future psychologists, ways of its formation); personal-active (methods, techniques, procedures, productive technologies, and tools of implementing psychological knowledge in work by specialities); reflective-evaluative components (an ability to professional and personal reflective). …”
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Knowledge, Attitude, and Practice of Medical Staff Towards Metabolic Syndrome in Schizophrenia in Chinese Hospitals: A Cross-Sectional Study by Wang Y, Yu X, Chen H, Tang C, Zhang N

“…Approximately 64.9% of participants had experience treating patients with schizophrenia and metabolic syndrome, and this experience was significantly associated with higher practice scores. Structural equation model analysis revealed that knowledge influenced attitude (β = 0.10), attitude influenced practice (β = 0.82), and knowledge directly influenced practice (β = 0.50).Conclusion: Medical staff possess adequate knowledge, positive attitude, and proactive practice concerning metabolic syndrome in schizophrenia. …”
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