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Suggested Topics within your search.
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Cardioprotective effects of liposomal resveratrol in diabetic rats: unveiling antioxidant and anti-inflammatory benefits
Published 2024-12-01“…Notably, LR modulated apoptotic regulators, including caspase, Bcl2, and Bax, suggesting a role in regulating programmed cell death. These biochemical alterations were consistent with improved structural integrity of cardiac tissue as revealed by histological examination. …”
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In silico and in vivo Study of the Anti-Inflammatory Activity of Azomethine Derivatives of 2-amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide and 2-substituted 5,6,7,8-tetra...
Published 2025-02-01“…In silico prediction of anti-inflammatory activity was performed using the AutoDock 4.0 program. The virtual structures of the test compounds were constructed in HyperChem 8.0.4. …”
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12224
Efficacy of neoadjuvant chemotherapy with docetaxel and cisplatin in patients with squamous cell carcinoma of the oral cavity at high risk of progression
Published 2025-07-01“…At the 1st stage of our study, we retrospectively analyzed the data of 98 patients and determine that the NACT for patients with oral cavity squamous cell carcinoma, with 3 or more factors of an unfavorable prognosis (peripheral blood parameters indicating the presence of systemic inflammation, reduced level of infiltration of tumor structures by CD8‑tumor infiltrating lymphocytes and low expression of programmed death-ligand 1 (PD-L1) on tumor and immune cells) significantly reduces the risk of death and disease progression: hazard ratio 0.33; 95 % confidence interval 0.13–0.86; p = 0.0231. …”
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Transitioning to adult care in youth-onset diabetes: a scoping review of socio-ecological factors in youth-onset type 2 diabetes compared to type 1 diabetes
Published 2025-05-01“…Identified challenges associated with the transitioning period in Y-T2D were societal (structural bias, poverty, inadequate social support), health cultural (limited access to adult health-care providers), psychological (feelings of anxiety and fear of transition), and behavioral (difficulty with medication adherence). …”
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Obstacles to effective communication between physical/occupational therapists and patients in the Saudi Arabian context: a cross-sectional study
Published 2024-12-01“…Future research should focus on longitudinal studies and specific communication training programs.…”
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Quality of care delivery in patients with acute heart failure: insights from the international REPORT-HF registryResearch in context
Published 2025-02-01“…Improving QoC by addressing structural barriers and quality improvement programs may improve the outcomes of patients with HF. …”
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Seasonal and Environmental Influences on the Gut Microbiota of South China Tigers (<i>Panthera tigris amoyensis</i>)
Published 2025-05-01“…Principal coordinate analysis (PCoA) based on Bray–Curtis distances revealed significant differences in the community structures of both bacterial (Adonis, R<sup>2</sup> = 0.2364, <i>p</i> = 0.001) and fungal (Adonis, R<sup>2</sup> = 0.1542, <i>p</i> = 0.001) communities across different seasons and environments. …”
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Human lung cancer neutrophils generate NETs with preserved anti-tumor cytotoxicity but impaired anti-migratory activity
Published 2025-08-01“…Neutrophil extracellular traps (NETs) are DNA-protein structures released during a form of programmed neutrophil death known as NETosis. …”
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Chloroquine induces eryptosis in P. falciparum-infected red blood cells and the release of extracellular vesicles with a unique protein profile
Published 2025-05-01“…Notably, the outward budding and blebbing of the iRBC plasma membrane led to the formation of EVs, which are complex structures with unique functional properties. Proteomic characterization of EVs from CQ-treated iRBCs revealed a high enrichment of proteasome and ribosome protein clusters. …”
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Assessing the foreign economic security of Ukraine
Published 2024-11-01“…At the same time, the growth of foreign economic security is recorded in the period of stabilization during the implementation of structural reforms: 2005–2008 – the period after the Orange Revolution, 2014–2016 – the period of growth after the Revolution of Dignity, 2021 – post-pandemic recovery. …”
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Genetic risk factors underlying white matter hyperintensities and cortical atrophy
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In Vivo Cell Migration and Growth Within Electrospun Porous Nanofibrous Scaffolds with Different Pore Sizes in a Mouse Pouch Model
Published 2025-05-01“…Cellular infiltration into traditional electrospun nanofibers (NFs) is limited due to their dense structures. We were able to obtain polycaprolactone (PCL) NFs with variable and defined pore sizes and thicknesses by using a customized programmed NF collector that controls the moving speed during electrospinning. …”
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Implementation and Costs of an Agroforestry System in a Degraded Area of the Brazilian Semi-Arid Region
Published 2025-04-01“…Specifically, we analyzed the system’s establishment process, estimated its costs, assessed structural development over time, and compared species performance and carbon accumulation across different biodiversity arrangements. …”
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Stress among police officials in Kerala, India: an analysis of organizational and operational factors
Published 2025-05-01“…The present study examines the specific stressors associated with the operational demands and organizational structures experienced by police officers in the state of Kerala, India. …”
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Predicting HIV self-testing intentions among Chinese college students: a dual-model analysis integrating health belief constructs and machine learning prioritization
Published 2025-07-01“…Random forest modeling prioritized these psychological constructs (mean decrease Gini >2.5), identifying male students and arts majors as critical subpopulations requiring targeted intervention.DiscussionOur dual-method analysis establishes that campus HIV control necessitates: 1) Gender-specific prevention programs addressing male students’ elevated risk exposure; 2) HBM-informed education strengthening self-efficacy and environmental cues; 3) Structural interventions reducing testing barriers through discreet service delivery. …”
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