Research on the optimization model of anti-breast cancer candidate drugs based on machine learning by Zhou Dong, Hong Chen, Yuchen Yang, Hairong Hao

“…Additionally, a multi-model fusion strategy and Particle Swarm Optimization (PSO) algorithm were employed to optimize both biological activity and ADMET properties, thereby improving the prediction of Caco-2, CYP3A4, hERG, HOB, and MN properties. …”
Get full text

PSA-Optimized Compressor Speed Control Strategy of Electric Vehicle Thermal Management Systems by Kun Xia, Lianglu Yu, Jingxia Wang, Wei Yu

“…Precise control of compressor speed, informed by real-time sensor data, is essential for improving TMS efficiency and extending EV range. This study proposes a control strategy based on the PID Search Algorithm (PSA), ensuring optimal thermal management for an integrated battery and cabin TMS. …”
Get full text

Class-aware multi-source domain adaptation algorithm for medical image analysis using reweighted matrix matching strategy. by Huiying Zhang, Yongmeng Li, Lei He, Wenbo Zhang, Yuchen Shen, Lumin Xing

“…These approaches collectively improve classification accuracy and domain adaptability. …”
Get full text

Optimization of Rotary Blade Wear and Tillage Resistance Based on DEM-MBD Coupling Model by Zhiqiang Mao, Yang Zhang, Keping Zhang, Jiuxin Wang, Junqian Yang, Xiaobao Zheng, Shuaikang Chen, Zhongqing Yang, Biao Luo

“…The optimized rotary blade achieves the effects of reduced resistance and wear, improves the lifespan of the blade, reducing material loss, and meeting the requirements of sustainable agricultural production.…”
Get full text

ADMET evaluation in drug discovery: 21. Application and industrial validation of machine learning algorithms for Caco-2 permeability prediction by Dong Wang, Jieyu Jin, Guqin Shi, Jingxiao Bao, Zheng Wang, Shimeng Li, Peichen Pan, Dan Li, Yu Kang, Tingjun Hou

“…We believe that the model developed in this study could represent a reliable tool for assessing Caco-2 permeability during early-stage drug discovery and the chemical transformation rules derived here could provide insights for optimizing Caco-2 permeability. Scientific contribution A comprehensive validation of various machine learning algorithms combined with diverse molecular representations on a large dataset for predicting Caco-2 permeability was reported. …”
Get full text

A novel trajectory learning method for robotic arms based on Gaussian Mixture Model and k-value selection algorithm. by Jingnan Yan, Yue Wu, Kexin Ji, Cheng Cheng, Yili Zheng

“…Experimental results demonstrate that, compared to the traditional Gaussian Mixture Model approach, the proposed method improves trajectory accuracy by more than 15%, as shown by reductions in both the Mean Absolute Error and the Root Mean Square Error. …”
Get full text

Robust Optimization for Microgrid Management With Compensator, EV, Storage, Demand Response, and Renewable Integration by Hamid Hematian, Mohamad Tolou Askari, Meysam Amir Ahmadi, Mahmood Sameemoqadam, Majid Babaei Nik

“…To efficiently solve this optimization problem, the C&CG algorithm is utilized. …”
Get full text

Leveraging a disulfidptosis-based signature to characterize heterogeneity and optimize treatment in multiple myeloma by Bingxin Zhang, Dong Zheng, Shuxia Zhu, Xinyi Zhang, Quanqiang Wang, Zhili Lin, Ziwei Zheng, Shujuan Zhou, Zixing Chen, Sisi Zheng, Enqing Lan, Luning Cui, Hansen Ying, Yu Zhang, Xuanru Lin, Qiang Zhuang, Honglan Qian, Xudong Hu, Yan Zhuang, Qianying Zhang, Zhouxiang Jin, Songfu Jiang, Yongyong Ma, Yongyong Ma, Yongyong Ma

Get full text

Optimizing electric vehicle energy consumption prediction through machine learning and ensemble approaches by Izhar Hussain, Kok Boon Ching, Chessda Uttraphan, Kim Gaik Tay, Adeeb Noor, Sufyan Ali Memon

“…The K-Nearest Neighbors (KNN) algorithm is employed as the base model, with hyperparameter optimization performed using GridSearchCV, RandomizedSearchCV, Optuna, and Particle Swarm Optimization (PSO). …”
Get full text

Data enhanced iterative few-sample learning algorithm-based inverse design of 2D programmable chiral metamaterials by Zhao Zeyu, You Jie, Zhang Jun, Du Shiyin, Tao Zilong, Tang Yuhua, Jiang Tian

“…In this way, the DEIFS algorithm replaces the time-consuming iterative optimization process with a faster and simpler approach that achieves accurate inverse design with dataset whose amount is at least one to two orders of magnitude less than most previous deep learning methods, reducing the dependence on simulated spectra. …”
Get full text

An Intelligent Optimization System Using Neural Networks and Soft Computing for the FMM Etching Process by Wen-Chin Chen, An-Xuan Ngo, Jun-Fu Zhong

“…Experimental results demonstrate a marked improvement in product yield and process stability while reducing manufacturing costs. …”
Get full text

Optimizing prediction of metastasis among colorectal cancer patients using machine learning technology by Raoof Nopour

Get full text

Data-Driven Robust Optimization for Solving the Heterogeneous Vehicle Routing Problem with Customer Demand Uncertainty by Jingling Zhang, Mengfan Yu, Qinbing Feng, Longlong Leng, Yanwei Zhao

“…Through test experiments, it is proved that the robust optimization model can effectively reduce the number of customers affected by the uncertainty, greatly improve customer satisfaction, and effectively reduce total cost and demonstrate that the improved algorithm also exhibits good performance.…”
Get full text

A Clustering-Guided Integer Brain Storm Optimizer for Feature Selection in High-Dimensional Data by Jia Yun-Tao, Zhang Wan-Qiu, He Chun-Lin

“…Since the number of feature clusters is far smaller than the size of original features, IBSO-C can find an optimal feature subset fast. Compared with several existing algorithms on some real-world datasets, experimental results show that IBSO-C can find feature subset with high classification accuracy at less computation cost.…”
Get full text

Multi-Objective Optimization of Machinability and Energy Consumption of Cast Iron Depending on Cooling Rate by Burak Öztürk, Fuat Kara

“…Energy efficiency has become a critical focus in sustainable production techniques and cost-effective machining processes. This variation directly influences machinability, with higher hardness generally improving surface quality. …”
Get full text

A Comparative Analysis of Hyper-Parameter Optimization Methods for Predicting Heart Failure Outcomes by Qisthi Alhazmi Hidayaturrohman, Eisuke Hanada

“…The XGBoost models exhibited moderate improvement (+0.01683) post-validation. Bayesian Search had the best computational efficiency, consistently requiring less processing time than the Grid and Random Search methods. …”
Get full text

Cognitive FDA-MIMO Radar Network’s Transmit Element Selection Algorithm for Target Tracking in a Complex Interference Scenario by Yingfei Yan, Haihong Tao, Jingjing Guo, Biao Yang

Get full text

Modeling and optimization of culture media for recombinant Helicobacter pylori vaccine antigen HpaA by Runqing Tan, Song Zhou, Min Sun, Yu Liu, Xiumei Ni, Jin He, Gang Guo, Kaiyun Liu

“…The H. pylori adhesin protein HpaA has demonstrated strong immunogenicity across various adjuvants and dosage forms, positioning it as a key candidate antigen for recombinant subunit vaccines against H. pylori. Optimizing fermentation culture conditions is an effective strategy to enhance product yield and lower production costs. …”
Get full text

An intelligent stochastic optimization approach for air cargo order allocation under carbon emission constraints. by Zhenzhong Zhang, Ling Zhang, Deqiang Fu, Weichun Li

“…The method finds the optimal solution through an improved adaptive large-scale neighborhood search algorithm and uses a scenario generation technique to generate the scenarios required for evaluating candidate solutions to the high-dimensional stochastic optimization problem. …”
Get full text

User Experience Optimization Researcb on Personalized Pusb Approacb of IPTV Service Based on Label of Contents by Yingbo Zhu, Jianwei Diao, Bo Kang, Shengqiang Liu

“…It is needed to introduce active personalized push approach of content in order to improve user experience, due to higher cost of remote controller than PC and mobile phone. …”
Get full text