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4181
TNBC response to paclitaxel phenocopies interferon response which reveals cell cycle-associated resistance mechanisms
Published 2025-02-01“…Single-cell RNA sequencing (scRNA-seq) of TNBC cells after paclitaxel treatment revealed upregulation of innate immune programs canonically associated with interferon response and downregulation of cell cycle progression programs. …”
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The dual role of PGAM5 in inflammation
Published 2025-02-01“…Phosphoglycerate mutase family member 5 (PGAM5) is a novel modulator of mitochondrial homeostasis in response to mechanical stimulation. Here we review the structure and sublocalization of PGAM5, introduce its importance in programmed cell death and summarize its crucial roles in the development and progression of inflammatory diseases such as pneumonia, hepatitis, neuroinflammation and aging. …”
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4184
Cardiac Magnetic Resonance in the Assessment of Atrial Cardiomyopathy and Pulmonary Vein Isolation Planning for Atrial Fibrillation
Published 2025-05-01“…Advanced imaging techniques, particularly cardiac magnetic resonance (CMR) imaging, have emerged as pivotal in the detailed assessment of atrial structure and function. CMR facilitates the precise measurement of left atrial volume and morphology, which are critical predictors of AF recurrence post-intervention. …”
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4185
Introduction to chicken genetic resources of India: a comprehensive review
Published 2025-06-01“…Findings indicate that despite their genetic richness, several indigenous breeds face the risk of genetic dilution and population decline. To address this, structured breeding programs, in situ and ex situ conservation strategies, and genomic selection techniques must be reinforced. …”
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4186
INDONESIAN UNIVERSITY STUDENTS' PERCEPTIONS OF CHATGPT FOR ENGLISH ESSAY WRITING [PERSEPSI MAHASISWA INDONESIA TERHADAP CHATGPT DALAM PENULISAN ESAI BAHASA INGGRIS]
Published 2025-01-01“…ChatGPT was deemed helpful for various reasons, with its ability to provide relevant materials, check vocabulary and sentence structures, generate ideas, and translate Indonesian sentences into English being the top five reasons. …”
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4188
FOXA1 enhances antitumor immunity via repressing interferon-induced PD-L1 expression in nasopharyngeal carcinoma
Published 2024-11-01“…Forkhead box A1 (FOXA1) is one of the earliest discovered pioneer factors, which can open up compact chromatin structures to facilitate the binding of other proteins to chromatin.Methods By using RNA sequencing, it was discovered that FOXA1 suppresses the activation of the interferon signaling pathway and the expression of the related interferon-responsive genes in NPC cells. …”
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4189
Quantum Vulnerability Analysis to Guide Robust Quantum Computing System Design
Published 2024-01-01“…For example, the estimated probability of success (ESP) is the state-of-the-art metric used to gauge quantum program performance. The ESP suffers poor prediction since it fails to account for the unique combination of circuit structure, quantum state, and quantum computer properties specific to each program execution. …”
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4190
Aberrant EZHIP expression drives tumorigenesis in osteosarcoma
Published 2025-07-01Get full text
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4191
Construction and validation of an instrument to assess knowledge about hepatitis B among nurses
Published 2025-06-01“…Conclusion: The instrument shows evidence of satisfactory content, appearance and internal structure validity to assess nurses’ knowledge about hepatitis B, thus it can be used to support the planning and evaluation of continuing education programs for nurses and undergraduate students.…”
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Health provider perspectives on differentiated service delivery for HIV in Oyo state, Nigeria: exploring the experiences of service providers from a demand perspective
Published 2025-08-01“…However, their success depends on addressing structural and operational challenges, tailoring approaches to local contexts, and strengthening health workforce capacity. …”
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4195
The novel BET‐CBP/p300 dual inhibitor NEO2734 is active in SPOP mutant and wild‐type prostate cancer
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4196
A Novel Approach for Comparing Selected Metabolites in Citrus Leaves and Fruits Across Datasets
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4197
The issue of credibility between customers’ perceptions and the attitude toward Facebook advertising
Published 2025-08-01“…This sample was chosen due to students’ high engagement with social media and their relevance as future marketing professionals, yielding 277 valid responses to be analyzed, and the hypotheses were tested using smart PLS through Structural Equation Modelling. The analysis revealed that Perceived Interactivity, Advertising Avoidance, and Privacy positively impacted attitudes towards Facebook advertisements, with coefficients and significance levels as follows: β = 0.122, t = 5.545, p < 0.003, β = 0.324, t = 2.643, p < 0.002, and β = 0.046, t = 3.833, p < 0.003, respectively. …”
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High-quality bonds: serine acetyltransferase 2 gene revealed by GWAS is associated with grain protein content in spring durum wheat
Published 2025-08-01“…A missense mutation (Gly325Ser) in the ninth exon of sat2 was associated with a 1.33% GPC increase in spring durum wheat recombinant inbred lines. Structural analysis indicated that the Gly325Ser mutation alters the SAT2 protein’s C-terminal α-helix, potentially influencing enzyme activity. …”
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Development of entrustable professional activities framework for clinical microbiology residency: a national multi-step consensus using modified Delphi study
Published 2025-05-01“…As the first step, a thorough literature review was undertaken to identify potential EPAs pertinent to clinical microbiology residency programs. Then, evaluation of EPAs for quality and structure using EQual rubric involved five experts in medical education and clinical microbiology, resulting in the confirmation of relevant EPAs. …”
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A pilot study on the effect of severe sleep fragmentation on aorta remodelling, neuroinflammation in a rat model
Published 2025-07-01“…Our preliminary findings support that SF alters aortic function, structure and biomechanical properties and release extracellular vesicles; and therefore these should be considered in preventive cardiovascular health programs.…”
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