Targeting MARCO in combination with anti-CTLA-4 leads to enhanced melanoma regression and immune cell infiltration via macrophage reprogramming by Hidenori Takahashi, Rana Falahat, Patricio Perez-Villarroel, James J Mulé

“…Macrophage Receptor with Collagenous Structure (MARCO) is one of a family of class-A scavenger receptors expressed by Mφ in the TME and is one of the most upregulated transcripts in dendritic cells (DC) following their ex vivo uptake of dead tumor cells. …”
Get full text

Flipping the curriculum for resident didactics: In-Training and certifying examination scores in an internal medicine residency. by Luke McCoy, Ronald Markert, Elysha Thoms, Olivia Noall, Kathryn Burtson

“…The curriculum followed a 13-block annual structure aligned with ABIM content areas. We compared IM-ITE and IM-CE scores of residents who completed the full flipped curriculum to those trained under the prior LB model.…”
Get full text

The role of Universal Grammar and crosslinguistic influence in the interpretation of recursive set-subset adjectives in adult Romanian L1-English L2 bilinguals by Adina Camelia Bleotu, Adina Camelia Bleotu, Deborah Foucault, Tom Roeper, Usha Lakshmanan

Get full text

Clinical and Epidemiological Characteristics of Hepatocellular Carcinoma in the Republic of Saha (Yakutia) by S. S. Sleptsova, S. I. Malov, E. D. Savilov, S. I. Semenov, V. K. Semenova, L. A. Stepanenko, O. B. Ogarkov, I. V. Malov

“…The Republic of Sakha (Yakutia) is a hyperendemic region of the Russian Federation in terms of the incidence of hepatocellular carcinoma with a predominance of the male population in its structure. The rate of decrease in the incidence of liver cancer in the country will depend on the effectiveness of the regional program for the elimination of viral hepatitis and the decrease in the incidence of cirrhosis of the liver of non-infectious etiology.…”
Get full text

CanvasHero: The role of artificial intelligence in cultivating resilience among children and youth using the 6-part story method in mass war trauma by Yuval Haber, Inbar Levkovich, Iftach Tzafrir, Karny Gigi, Dror Yinon, Dorit Hadar Shoval, Zohar Elyoseph

Get full text

THE SUMMER TEMPERATURES FORECAST BY THE METHOD OF SINGULAR-SPECTRAL ANALYSIS IN THE SOUTH OF RUSSIA IN 2019-2023 by A. A. Tashilova, B. A. Ashabokov, L. A. Kesheva, N. V. Teunova

“…Using of the first twenty main components (MC20) made it possible to study and restore the internal structure of the entire time series as accurately as possible for a subsequent forecast for 5 years. …”
Get full text

Identifying predictors and assessing causal effect on hypertension risk among adults using Double Machine Learning models: Insights from Bangladesh Demographic and Health Survey. by Probir Kumar Ghosh, Md Aminul Islam, Md Ahshanul Haque, Md Tariqujjaman, Novel Chandra Das, Mohammad Ali, Md Rasel Uddin, Md Golam Dostogir Harun

“…We used logistic regression, Random forest model, Double Machine Learning (DML), and Shapley Additive exPlanations (SHAP) based on a pre-defined causal structure.<h4>Results</h4>The dataset included 11,815 individuals, and the prevalence of hypertension was 38.40%. …”
Get full text

Functional annotation of the Hippo pathway somatic mutations in human cancers by Han Han, Zhen Huang, Congsheng Xu, Gayoung Seo, Jeongmin An, Bing Yang, Yuhan Liu, Tian Lan, Jiachen Yan, Shanshan Ren, Yue Xu, Di Xiao, Jonathan K. Yan, Claire Ahn, Dmitry A. Fishman, Zhipeng Meng, Kun-Liang Guan, Ruxi Qi, Ray Luo, Wenqi Wang

Get full text

Methods to improve teaching effciency for students from the People’s Republic of China at technical universities by K. P. Baslyk, V. P. Pechnikov, N. A. Tukhtarova

“…The research materials include printed works for which the appropriate methods of analysis of scientific texts are used: ● excerpts from the development programs of space industry and joint educational programs of Russia and China – aspect and diachronic method of analysis of priority areas of development of the higher school of China and promising areas of cooperation; ● the curricula of professional education in various areas and specialties of Bauman Moscow State Technical University – aspect analysis of the general provisions of engineering training programs; ● manuals on the “Basics of Rocket and Space Technology” (BRST) of Russia (USSR) and China – critical, comparative and conceptual analysis of the content features, methods and style of presentation of the material; ● BRST – aspect and phenomenological analysis of the structure and content of a special technical discipline; ● scientific works on pedagogy and psychology – aspect and system analysis of features of the education system, educational behavior and bilingual opportunities of students from China.The paper applied the problem analysis method to tackle the task in the context of publications’ shortage on teaching special technical disciplines to foreigners. …”
Get full text

Diversity and distribution of helminth communities of the rodent Akodon montensis Thomas, 1913 (Rodentia: Cricetidae: Sigmodontinae) in preserved and altered environments in the At... by Camila dos Santos Lucio, Thiago dos Santos Cardoso, Rosana Gentile, Viviane Brito Dias, Milton Cezar Ribeiro, Bernardo Rodrigues Teixeira, Paulo Sérgio D'Andrea

Get full text

¹¹⁹Sn Element-Specific Phonon Density of States of BaSnO₃ by Alexey Rulev, Hongxin Wang, Selma Erat, Murat Aycibin, Daniel Rentsch, Vladimir Pomjakushin, Stephen P. Cramer, Qianli Chen, Nobumoto Nagasawa, Yoshitaka Yoda, Artur Braun

Get full text

The rare hemoglobin variants Hb O-Arab and Hb D-Punjab identified in population-based genetic screening throughout Guangxi, China by Chunrong Gui, Chunrong Gui, Zifeng Cheng, Yongsheng Chen, Yunting Ma, Hongfei Chen, Wei Wei, Wei Wei, Xianda Wei, Xianda Wei, Juliang Liu, Juliang Liu, Xu Zhou, Qianqian Du, Yinghui Lai, Baoheng Gui, Baoheng Gui, Baoheng Gui

“…The in silico structural predictions based on Alphafold2 were performed for the rare variants identified. …”
Get full text

Calpastatin and myostatin genes polymorphism and their association with slaughter traits in the Gashun Soviet Merino breed grown in southern Russia by Nadezhda V. Shirokova, Vladimir K. Fiodorov, Izabella G. Kazarova, Ivan F. Gorlov, Marina I. Slozhenkina, Elena Y. Anisimova, Ekaterina V. Karpenko

“…Data on the CAST and MSTN gene polymorphism and the genetic structure of the studied sheep population were obtained for the first time, their association with slaughter traits was revealed, and desirable genotypes CAST_MN and MSTN_AG were determined. …”
Get full text

Changes in subarctic Pacific phytoplankton communities over the last two decades by Marta Konik, Marta Konik, Marta Konik, Brian P. V. Hunt, M. Angelica Peña, Toru Hirawake, Christian Marchese, Christian Marchese, Christian Marchese, Perumthuruthil Suseelan Vishnu, Perumthuruthil Suseelan Vishnu, Astrid Bracher, Astrid Bracher, Hongyan Xi, Maycira Costa

Get full text

Study of Some Thorium Isotopes near to the Closed Shell (82 and 126) by Nibras Hayder Hammood Eatiah, Mohsin Kadhim Muttaleb Al-Jnaby, Ghaidaa A. Hafedh Jaber Hussien

“…Using the interacting bosons model-one (IBM-1), the nuclear structure of the thorium isotopes ²²⁴Th, ²²⁶Th, and ²²⁸Th were examined in this study, which are near from closed shell 82 and 126. …”
Get full text

Methods for Predicting the Costs of Maintaining Nuclear Heritage Facilities in а Safe State by D. F. Iliasov, A. Y. Ivanov, E. O. Kuznetsova

“…In the research there was developed the methodology of isolation from the overall structure costs, associated with maintaining shutdown facilities and storage facilities for radioactive waste of nuclear industry enterprises. …”
Get full text

Anticoronavirus activity of C60 fullerene: in silico and in vitro screening by Василь Гурмач, Вячеслав Караушу, Зінаїда Клестова, Володимир Берест, Юрій Прилуцький

“…Methods: The Protein Data Bank was used to study the structural organization of the human ACE2 membrane protein. …”
Get full text

Una aproximación al ámbito laboral de las mujeres trans desde una perspectiva de la intervención social by Alejandro Hernández-Melián

“…For this purpose, a qualitative method is used through semi-structured interviews, with a total sample of six participants from different Autonomous Communities of Spain and from programs managed both from the public and the Third Social Sector. …”
Get full text

SURGERY OF BRAIN STEM CAVERNOUSES MALFORMATION by V. V. Stupak, Sh. Aul, A. G. Bobylev, M. V. Kutsenko, D. A. Dentsel, T. M. Shogunbekov, V. M. Bon, A. M. Gazeev, A. E. Simonovich, S. V. Tsvetovskiy

“…Cavernous malformations (CM), also known as cavernous angiomas or cavernomas, are benign vascular hamartomas having a sinusoidal type of wall structure.CM occurs in the brain stem with a frequency of 9–35 % of cases. …”
Get full text

Morphology of <i>Pulleniatina</i> (planktonic foraminifera) from optical microscopy, micro-CT, and SEM investigations by A. Fabbrini, A. Fabbrini, P. N. Pearson, A. Brombacher, A. Brombacher, F. Iacoviello, T. H. G. Ezard, B. S. Wade

“…We use these observations to document the comparative ontogeny and test structure of the six <i>Pulleniatina</i> morphospecies in the context of an evolutionary model involving two diverging species lineages.…”
Get full text