Neural network-based prediction of incident atrial fibrillation using the trans-thoracic echocardiography parameters: a prospective study by Stanislav N. Kotlyarov, Alexandr V. Lyubavin

“…Conclusion: The NN used in the study meets the goal of the binary differentiation, i. e. it allows to differentiate the heart structure and function typical for AF from those not typical for AF. …”
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Extracellular Vesicles Present in Bone Marrow Mesenchymal Stromal/Stem Cell Conditioned Media Restore Spermatogenesis in Azoospermic Mice by Rano Zhankina, Afshin Zare, Alireza Afshar, Arezoo Khoradmehr, Mohammad Reza Dorvash, Farhad Rahmanifar, Nader Tanideh, Omid Koohi Hosseinabadi, Ali Arabi Monfared, Shahrokh Zare, Nadiar Mussin, Asset Askerovich Kaliyev, Ulanbek Zhanbyrbekuly, Amin Tamadon

“…Additionally, protein structure extraction, protein-protein docking analysis, and data visualization were conducted.Results: Histomorphometry and flow cytometry showed that most seminiferous tubules in the therapy groups exhibit­ed normal morphology and restored spermatogenesis, unlike the azoospermia group. …”
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Deciphering maize resistance to late wilt disease caused by Magnaporthiopsis maydis: agronomic, anatomical, molecular, and genotypic insights by Walaa R. Abdelghany, Mohsen M. Elsharkawy, Ramy N. F. Abdelkawy, Reda I. Omara, Khaled Abdelaal, Abeer H. Abbas, Wael N. Hozzein, Tarek Essa, Dalal Hussain ALkhalifah, Ayman H. Abou Tabl

“…Anatomical examination showed superior root structure in resistant genotypes, particularly SC2031. …”
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Discovery and clinical translation of ceperognastat, an O‐GlcNAcase (OGA) inhibitor, for the treatment of Alzheimer's disease by William Kielbasa, Paul Goldsmith, Kevin B. Donnelly, Hugh N. Nuthall, Sergey Shcherbinin, Adam S. Fleisher, Jörg Hendle, Susan L. DuBois, Stephen L. Lowe, Feiyu Fred Zhang, Eric M. Woerly, Nicolas J.‐F. Dreyfus, David Evans, Jeremy Gilmore, Michele Mancini, Cristian C. Constantinescu, Roger N. Gunn, David S. Russell, Emily C. Collins, Miroslaw Brys, Michael L. Hutton, Dustin J. Mergott

“…METHODS A multidisciplinary approach was used to identify ceperognastat (LY3372689) as a potent OGA inhibitor, including an extensive discovery effort with synthetic chemistry, structure‐based drug design, and in vivo OGA enzyme occupancy studies. …”
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Presenting the entrepreneurship development model in the national oil refining industry with the approach of environmental damage prevention by Jalal Abdi, Reza Yousefi Saeedabadi, Maryam Taghvaee Yazdi

“…Daneshniya et al, (2021) showed that a total of 27 main concepts can be expressed as obstacles to the development of entrepreneurship in Iran; so that 10 concepts of political environment, cultural, legal, educational, technology, government structure, macroeconomic, financial environment, geographical environment and production structure are causal conditions categorized with two categories of institutional and economic factors. 7 concepts of efficiency, opportunism, creativity, risk-taking, need for success, desire for independence, and power-seeking of entrepreneurs were identified with the category of entrepreneurs' characteristics and the background conditions of lack of entrepreneurship development. …”
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Advancing ocean monitoring and knowledge for societal benefit: the urgency to expand Argo to OneArgo by 2030 by Virginie Thierry, Hervé Claustre, Orens Pasqueron de Fommervault, Nathalie Zilberman, Kenneth S. Johnson, Brian A. King, Susan E. Wijffels, Udaya T. V. S. Bhaskar, Magdalena Alonso Balmaseda, Mathieu Belbeoch, Marine Bollard, Jacqueline Boutin, Phillip Boyd, Romain Cancouët, Fei Chai, Stefano Ciavatta, Rich Crane, Sophie Cravatte, Sophie Cravatte, Giorgio Dall’Olmo, Damien Desbruyères, Paul J. Durack, Andrea J. Fassbender, Katja Fennel, Yosuke Fujii, Florent Gasparin, Alberto González-Santana, Claire Gourcuff, Alison Gray, Helene T. Hewitt, Steven R. Jayne, Gregory C. Johnson, Nicolas Kolodziejczyk, Arnaud Le Boyer, Pierre-Yves Le Traon, Pierre-Yves Le Traon, William Llovel, M. Susan Lozier, John M. Lyman, John M. Lyman, Elaine L. McDonagh, Elaine L. McDonagh, Adrian P. Martin, Benoit Meyssignac, Kristian S. Mogensen, Tamaryn Morris, Peter R. Oke, Walker O. Smith, Breck Owens, Noé Poffa, Joanna Post, Dean Roemmich, Ryan R. Rykaczewski, Shubha Sathyendranath, Megan Scanderbeg, Carolyn Scheurle, Oscar Schofield, Karina von Schuckmann, James Scourse, Janet Sprintall, Toshio Suga, Toshio Suga, Marina Tonani, Esmee van Wijk, Esmee van Wijk, Xiaogang Xing, Hao Zuo

“…Effective and sustainable monitoring of the physical, biogeochemical state and ecosystem structure of the ocean, to enable climate adaptation, carbon management and sustainable marine resource management is urgently needed. …”
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Building a collaborative ecosystem across the IDeA-CTR networks in response to a public health emergency by A. Jerrod Anzalone, Sharon Patrick, Amber Abel, Brad Price, Elizabeth Reisher, Kent Ripplinger, Mary Emmett, Ronald Horswell, San Chu, William B. Hillegass, Francisco S. Sy, Brian Melancon, H. Timothy Bunnell, Lucio Miele, Mary Helen Mays, Joseph Keawe‘aimoku Kaholokula, Elizabeth S. Chen, Karen M. Crowley, Indra Neil Sarkar, Susan L. Santangelo, Clifford J. Rosen, Jeremy Harper, David Bard, William Beasley, Sally L. Hodder

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Pre-clinical allergenicity assessment of IgE epitope-targeted Der p 2 mutants demonstrate potential as hypoallergenic AIT candidates by Glorismer Pena-Amelunxen, Mohadeseh Asghari, Kriti Khatri, Jill Glesner, Serge A. Versteeg, Serge A. Versteeg, Ronald van Ree, Ronald van Ree, Martin D. Chapman, Scott A. Smith, Maksymilian Chruszcz, Anna Pomés, Lorenz Aglas, Lorenz Aglas, Lorenz Aglas

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Dynamics and Trends in the Incidence of Rabies in the Russian Federation and some Adjacent Regions of Eurasia in 2013–2021 by O. N. Zaykova, M. A. Losich, E. V. Rusakova, O. A. Verkhovsky, A. A. Shabeykin, T. V. Grebennikova

“…As a result, the proportion of dogs and cats in the morbidity structure has significantly increased, which, given their proximity to humans, ensures the maintenance of a high level of epidemiological risk. …”
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Comparative transcriptome analysis reveals molecular mechanisms of resistance in Chinese cabbage to Plasmodiophora brassicae pathotype 11 by Yue Qiu, Yue Qiu, Yue Qiu, Jinhao Zhang, Jinhao Zhang, Chunju Deng, Chunju Deng, Jiasheng Yuan, Jiasheng Yuan, Bowen Wang, Bowen Wang, Han Meng, Han Meng, Mohamed Mohany, Liting Zeng, Liting Zeng, Lanfang Wei, Lanfang Wei, Waqar Ahmed, Guanghai Ji, Guanghai Ji

“…Microscopic analysis at 21 dai revealed that the resistant cultivar (JP) root structure remained largely unaffected, while the roots of the susceptible cultivar (83-1) exhibited significant tissue distortion and gall formation, underscoring the effectiveness of the resistance mechanisms. …”
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Association Analysis of <i>SLC11A1</i> Polymorphisms with Somatic Cell Score in Chinese Holstein Cows by Kai Liu, Yufang Liu, Tuo Li, Qiuling Li, Jinyu Wang, Yongfu An, Yuze Yang, Kaiyang Li, Mingxing Chu

“…The bioinformatic analysis showed that these mutations affected the secondary and tertiary structure of <i>SLC11A1</i> mRNA, suggesting that they may affect gene expression or protein translation and function. …”
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Deep learning and genomic best linear unbiased prediction integration: An approach to identify potential nonlinear genetic relationships between traits by F. Shokor, P. Croiseau, H. Gangloff, R. Saintilan, T. Tribout, T. Mary-Huard, B.C.D. Cuyabano

“…Deep learning (DL) offers a promising alternative for capturing nonlinear genetic relationships due to its ability to identify complex patterns without prior assumptions about the data structure. We proposed a novel hybrid model that that combines both DL and GBLUP (DLGBLUP), which uses the output of the traditional GBLUP, and enhances its predicted genetic values (PGV) by accounting for nonlinear genetic relationships between traits using DL. …”
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The effects of Transcendental Meditation on emotional intelligence, stress, fatigue, and sleep quality among Ayurvedic medical students in India by Carol Paredes, Sandy Nidich, Gunvant Yeola, Asmita Wele, Santosh Kamble, Kamalakar Tehre, Robert Keith Wallace, Maxwell Rainforth

“…An autoregressive [AR(1)] covariance structure was specified to account for repeated measures. …”
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CHARACTERISTICS OF PSYCHOLOGICAL MATURITY AS A SOFT-SKILL OF A MODERN PERSONALIT by Mitchenko Kateryna

“…The aim of the article is to substantiate the essence and component structure of psychological maturity, and the set of soft skills as an integral part of an individual’s psychological maturity. …”
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Symptom network analysis of pregnancy stress, depressive symptoms and quality of life: a cross-sectional study of pregnant women in Xinjiang, China, 2023–2024 by Sufeila Shalayiding, Weicui Meng, Xiaoting Wang, Bahedana Sailike, Ting Jiang

“…Methods From February 2023 to January 2024, a convenience sampling method was used to conduct a cross-sectional study of 1,349 pregnant women in a tertiary hospital in the Xinjiang Uygur Autonomous Region of China using the Patient Health Questionnaire Depressive Symptom Cluster and the Stress in Pregnancy and Health-Related Quality of Life Scale, to construct a network to perform network estimation, and to determine core nodes of the network structure based on the centrality indexes. Results Maternal pregnancy stress score (1.71 ± 0.55), depressive symptoms (15.36 ± 4.70), and quality of life had the highest social functioning score (74.45 ± 12.63) and the lowest physical functioning score (65.18 ± 26.75). …”
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NPT100-18A rescues mitochondrial oxidative stress and neuronal degeneration in human iPSC-based Parkinson’s model by Julian E. Alecu, Veronika Sigutova, Razvan-Marius Brazdis, Sandra Lörentz, Marios Evangelos Bogiongko, Anara Nursaitova, Martin Regensburger, Laurent Roybon, Kerstin M. Galler, Wolfgang Wrasidlo, Beate Winner, Iryna Prots

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Territorially Stratified Modeling for Sustainable Management of Free-Roaming Cat Populations in Spain: A National Approach to Urban and Rural Environmental Planning by Octavio P. Luzardo, Ruth Manzanares-Fernández, José Ramón Becerra-Carollo, María del Mar Travieso-Aja

“…These data were stratified by municipal population size and applied to national census figures to generate a model-ready demographic structure. We then implemented a stochastic simulation using Vortex software to project long-term population dynamics over a 25-year horizon. …”
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Modeling the Meaning of Individual Words Using Cultural Cartography and Keystroke Dynamics by Tatiana A. Litvinova, Olga V. Dekhnich

“…The material of the study is a newly developed dataset containing associative reactions to the keywords of Russian culture, anonymized data about the informants, as well as the reaction time while producing associations measured using a program that records keystrokes. The proposed research methodology includes both the existing approaches (automatic extraction of relations from texts based on data from language models and methods of vector semantics, i.e., “cultural cartography using word embeddings”) and a new list of features developed by the authors to describe individual differences in the meaning of a word based on the data from neurobiology about the meaning structure of word. …”
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Comparative Analysis of Biochemical Parameters, Thermal Behavior, Rheological Features, and Gelling Characteristics of Thai Ligor Hybrid Chicken and Broiler Meats by Ngassa Julius Mussa, Chantira Wongnen, Warangkana Kitpipit, Worawan Panpipat, Mingyu Yin, Siriporn Riebroy Kim, Manat Chaijan

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A Proposed Diagnostic and Treatment Algorithm for the Management of Lumbar Discogenic Pain by Lorio MP, Beall DP, Myers TJ, Naidu RK, McRoberts WP, Davis TT, Gage EG, Calodney AK, Verrills P, De Palma MJ, Amirdelfan K, Block JE

“…., Walnut Creek, CA, USA; 12Private Practice, San Francisco, CA, USACorrespondence: Jon E Block, Private Practice, 2210 Jackson Street, Ste. 401, San Francisco, CA, 94115, USA, Tel +1 415-775-7947, Email jb@drjonblock.comBackground: There is renewed interest in the intervertebral disc as a target for treatments aimed at ameliorating lumbar discogenic pain by restoring and preserving the natural structure and function of this component of the vertebral motion segment.Methods: Using a modified Delphi methodology involving a panel of 11 experts, we developed a simple, understandable clinical algorithm to serve as a foundation for objective decision making regarding the diagnosis and treatment of lumbar discogenic pain throughout the entire continuum of care. …”
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