Repurposing FDA-approved drugs targeting FZD10 in nasopharyngeal carcinoma: insights from molecular dynamics simulations and experimental validation by Chawalit Ngernsombat, Utid Suriya, Pongphol Prattapong, Kanika Verma, Thanyada Rungrotmongkol, Thananya Soonkum, Sakonwan Kuhaudomlarp, Tavan Janvilisri

Get full text

Genome wide population genetics and molecular surveillance of insecticide resistance in Anopheles stephensi mosquitoes from Awash Sebat Kilo in Ethiopia by Holly Acford-Palmer, Fitsum G. Tadesse, Emilia Manko, Jody E. Phelan, Matthew Higgins, Ashley Osborne, Mojca Kristan, Thomas Walker, Teun Bousema, Louisa A. Messenger, Taane G. Clark, Susana Campino

“…Understanding population structure, gene flow between populations, and the distribution of insecticide resistance mutations is essential for guiding effective malaria control strategies. …”
Get full text

Solid-state calculations for iterative refinement in quantum crystallography using the multipole model by Michael Patzer, Christian W. Lehmann

“…Multipole parameters are generated from these structure factors using the XD program and are fixed during least-squares refinement. …”
Get full text

Protocol to develop a 3D mouse autologous lung tumor-immune spheroid co-culture model to advance radiotherapy-based treatments by Sergio León, Sofía Torres Quintas, Nerea Otegui, Miriam Redrado, José Javier Aristu, María José Oliveira, Alfonso Calvo, Flávia Castro, Diego Serrano

Get full text

Pedigree analysis of the Latvian Warmblood horse heavy type population by Viktorija Nikonova, Daina Jonkus, Liga Paura

“…The aim of the study was to analyse the genetic structure, inbreeding and effective population size of the Latvian warmblood heavy type (LSB) horse population. …”
Get full text

Organizational and Economic Mechanism of Managing Aviation Infrastructure for Ship Traffic along the Northern Sea Route by Tatyana A. Chernyak

“…The author has systematized the necessary management methods and supplemented the elements of the management subject structure, necessary and sufficient for the timely execution of the organizational decisions planned by the federal program.…”
Get full text

Identification of Novel Mutations in FAH Gene and Prenatal Diagnosis of Tyrosinemia in Indian Family by Jayesh J. Sheth, Chitra M. Ankleshwaria, Rajeshwari Pawar, Frenny J. Sheth

“…It leads to the identification of heterozygous status for both c.648C>G (p.Ile216Met) and c.1159G>A (p.Gly387Arg) mutations in exons 8 and 13, respectively, in the parents. The experimental program PolyPhen, SIFT, and MT predicts former missense point mutation as “benign” that creates a potential donor splice site and later one as “probably damaging” which disrupts secondary structure of protein.…”
Get full text

Design of New Ravigneaux Planetary Gearset Automatic Transmissions for Automobile by Zhang Jian, Xue Huanzhang

“…The essential constrain conditions are established by analyzing the structure of the Ravigneaux transmission. The assembly condition minimum error can be calculated by the essential constrain conditions and the condition that make a planetary gear meshes with two others properly. …”
Get full text

SOMATOTYPE AND PHYSICAL DEVELOPMENT OF 11-YEAR-OLD GIRLS DURING HANDBALL TRAINING by H. Draganova

“…Nowadays, knowledge of body structure is increasingly attracting the interest of the scientific community, as it is known to be relevant to performance in sports.The present study is aimed at tracking the dynamics of anthropometric indicators and somatotype in 11-year-old girls. …”
Get full text

Design and implement of IPTV content repository based on graph database by Xin CAI, Yilong RUAN, Yirong SHI

“…The traditional way of using relational database to format conversion and storage of knowledge has limitation in the model structure complexity and query visualization and efficiency. …”
Get full text

Chapter 10 — Selecting Quality Trees from the Nursery by Edward F. Gilman, Laura Paterson Sadowski

“…Sadowski, is part of the Urban Forest Hurricane Recovery Program series. It discusses site conditions and after-care as related to maximum tree size at planting, root ball characteristics, appropriate tree production method, and tree structure, and describes quality factors to evaluate. …”
Get full text

Chapter 10 — Selecting Quality Trees from the Nursery by Edward F. Gilman, Laura Paterson Sadowski

“…Sadowski, is part of the Urban Forest Hurricane Recovery Program series. It discusses site conditions and after-care as related to maximum tree size at planting, root ball characteristics, appropriate tree production method, and tree structure, and describes quality factors to evaluate. …”
Get full text

Pour ou contre la Rénovation ? Inégalités résidentielles, mobilisations et appropriations des immeubles khrouchtchéviens à Moscou by Guenola Inizan

“…Based on a field study carried out in a muscovite neighborhood, this paper shows the large variety of housing situations, due to the heritage of the soviet housing structure and the development of the housing market. …”
Get full text

The Modification of Assessment Task Dimensions in Support of Student Progression in Legal Skills Development by Clair Hughes

“…The author queries whether institutions and accrediting bodies gone too far in accepting online practical legal training courses as an alternative for the more traditional face-toface course structure? After considering the relationship between training and the standards of the profession the author focuses on the literature pertaining to online delivery generally and in the area of legal education. …”
Get full text

MAP2 phosphorylation: mechanisms, functional consequences, and emerging insights by Jiali Lyu, Jiali Lyu, Andrew G. DeMarco, Robert A. Sweet, Robert A. Sweet, Robert A. Sweet, Melanie J. Grubisha, Melanie J. Grubisha

Get full text

Penguatan budaya hukum masyarakat untuk menghasilkan kewarganegaraan transformatif by Iman Pasu Purba

Get full text

Genetics of primary congenital hypothyroidism: three decades of discoveries and persisting etiological challenges by Athanasia Stoupa, Aurore Carré, Michel Polak, Gabor Szinnai, Nadia Schoenmakers

“…Primary congenital hypothyroidism (CH) is the most common neonatal endocrine disorder, and may be etiologically subdivided into thyroid dysgenesis, referring to abnormal thyroid development, and dyshormonogenesis, where a defective thyroid hormone biosynthesis pathway results in inadequate hormone production despite a structurally intact gland. Delayed treatment of neonatal hypothyroidism may result in irreversible neurodevelopmental impairment; therefore, where available, CH screening programs facilitate prompt diagnosis. …”
Get full text

Biopolymer from <i>Annona muricata</i> Residues as a Potential Sustainable Raw Material for Industrial Applications by Igor F. S. Ramos, Samuel C. Dias, Talissa B. C. Lopes, Francisco T. dos S. Silva Júnior, Ricardo de Araújo, Stanley J. C. Gutierrez, Claudia Pessoa, Josy A. Osajima, Marcia S. Rizzo, Edson C. Silva-Filho, Manuela Amorim, Óscar Ramos, Alessandra B. Ribeiro, Marcilia P. Costa

Get full text

Public-type MFOs as an element of financial system by А. N. Pyshkin

“…The subject of the research is to define the structure of microfinance organizations (MFOs) with the Russian Region’s authorities within the founders (participants, shareholders). …”
Get full text

Professional development for faculty in Uzbekistan by Tina A. Coffelt, Jacek A. Koziel, Jacek A. Koziel

“…Agricultural and biosystems engineering and English faculty members at a US Midwest university forged an interdisciplinary partnership to virtually deliver a 5-month program to an initial cohort of 68 participants. Topics included research ethics, experimental and survey research design, and structure of scientific papers, among others. …”
Get full text