Adjuvanted RNA Origami—A Tunable Peptide Assembly Platform for Constructing Cancer Nanovaccines by Theresa Yip, Xinyi Tu, Xiaodong Qi, Hao Yan, Yung Chang

“…Conclusions: Our findings have significant implications for peptide vaccine design regarding peptide dosages and structural stability of RNA-OG complexed with peptides, which could guide the development of more effective peptide vaccines for cancer immunotherapy.…”
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Critical care, critical gaps: assessment of burnout and behavioral profiles of ICU healthcare workers in China—a multicenter cross-sectional study by Chao Qing Zhang, Xing Li, Lei He, BinBin Xu, Yan Wu, Junjie He, Wei Wang, Zhong Qian Lu

“…Gender, marital status, and ICU type were non-significant.ConclusionBurnout in ICU HCWs persists as a structural-behavioral challenge post-pandemic. Interventions should prioritize institutional support, equitable mental health access, and inclusion of vulnerable groups. …”
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FORMATION OF NATIVE AMERICAN WRITTEN LITERARY TRADITION by Oksana G. Shostak

“…In the article we used such methods as: historical-literary and historical-cultural methods as well as elements of structural analysis. The research deals with the ways of actualizing one of the most powerful concepts of the modern world – that of ethnicity, which stands out as a constituent of the basic Native American identity concept originated in the late 20th – early 21st centuries. …”
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A novel hybrid fuzzy analytical hierarchy process–game theory model for prioritizing factors affecting the deterioration of water pipelines by Eslam Mohammed Abdelkader, Tarek Zayed, Nehal Elshaboury

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A Model for Diagnosing the Cognitive Activity of Students of Secondary Vocational Education System in Teaching Computer Science by K. Timofeeva

“…Cognitive activity in the context of the study is defined as a cognitive, psychological and social response to the cognitive process, which determines the personal and motivational interest in the conscious   acquisition of knowledge and skills of the subject area and is a structural component of the effectiveness of the educational process in computer science. …”
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Temporal trends in HIV prevention service access and use among female sex workers (FSW) in Mozambique: a comparative analysis 2011–2019 by Samuel Nuvunga, Áuria Ribeiro Banze, Rachid Muleia, Denise Chitsondzo Langa, Jahit Sacarlal, Cynthia Semá Baltazar

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Comprehensive RNA-Seq Analysis of Human Osteoclast Function in Response to <i>Bothrops moojeni</i> Venom Fractions: Pathways of Bone Resorption and Cytoskeletal Disruption by Fernanda D’Amélio, Hugo Vigerelli, Rodrigo Pinheiro Araldi, Isabel de Fátima Correia Batista, Daniel Carvalho Pimenta, Irina Kerkis

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Ability to form duplexes as a factor of intracellular microRNA distribution by S. A. Kuzmichev, A. V. Komelkov, E. M. Tchevkina

“…The regulation of the content of mature microRNAs (miRNAs) in different cell compartments – the nucleus (N) and the cytoplasm (C) – makes it possible to control their availability for participation in RNA-mediated interference processes. Structurally different miRNAs, processed from different precursors (pre-miRNA), can form duplexes between molecules containing complementary sequences. …”
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Birth prevalence and associated factors of congenital anomalies among neonates born at a public hospital in Awi Zone, Northwestern Ethiopia: institutional based cross-sectional stu... by Tsegaye Mehare, Yewbmirt Sharew

“…Abstract Background Congenital Anomalies, also known as birth defects, are structural, functional, or metabolic abnormalities present at birth or later in life that can result in physical or developmental impairments. …”
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System aspects of management technology for scientific and educational services by A. A. Zatsarinnyy, A. P. Shabanov

“…The state policy in the sphere of national security and socio-economic development of the Russian Federation, carried out in the face of new threats requires correcting structural imbalances in the economy. National interests should be implemented by means of strategic priorities in the various sectors of the economy, in the financial sphere - the timely implementation of government programs. …”
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MAPPING OF EVACUATION PATHS AND SOCIALIZATION OF DISASTER MITIGATION IN TOURISM AREAS: EDU WISATA LONTAR SEWU, GRESIK REGENCY by Ratnaningtyas Wahyu Kusuma Wardani, Tofan Agung Eka Prasetya, Neffrety Nilamsari

“…In addition, related to the results of non-structural disaster mitigation, showed that participants looked enthusiastic when socialization related to disaster mitigation was carried out and they were able to take part in disaster simulation activities properly and correctly and carry out self-rescue efforts by following the evacuation route that had been installed and heading to the gathering point according to the time. determined is 1 minute 25 seconds. …”
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SEGS-1 episomes generated during cassava mosaic disease enhance disease severity by Evangelista Chiunga, Evangelista Chiunga, Evangelista Chiunga, Catherine D. Aimone, Cyprian Rajabu, Mary M. Dallas, Joseph Ndunguru, José T. Ascencio-Ibáñez, Elijah M. Ateka, Linda Hanley-Bowdoin

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Pulmonary and functional hallmarks after SARS-CoV-2 infection across three WHO severity level-groups: an observational study by Patrícia Blau Margosian Conti, Maria Ângela Gonçalves Oliveira Ribeiro, Carla Cristina Souza Gomez, Aline Priscila Souza, Daniela Souza Paiva Borgli, Eulália Sakano, Mauro Alexandre Pascoa, Silvana Dalge Severino, Tayná Castilho, Fernando Augusto Lima Marson, Fernando Augusto Lima Marson, Fernando Augusto Lima Marson, José Dirceu Ribeiro, UNICOVID Study Group, Adyléia Aparecida Dalbo Contrera Toro, Aline Cristina Gonçalves, Andrea de Melo Alexandre Fraga, André Moreno Morcillo, Andressa Oliveira Peixoto, Andrei Carvalho Sposito, Bianca Aparecida Siqueira, Emília Silva Gonçalves, Emília Raposo Nascimento, Gil Guerra Junior, Jenniffer Tayna Orzechowski Furtado, Lucas Rodrigues de Moraes, Maria de Fatima Corrêa Pimenta Servidoni, Mariana Zorron, Marcos Tadeu Nolasco da Silva, Maíra Seabra Assumpção, Milena Baptistela Grotta, Renan Marrichi Mauch, Simone Appenzeller, Thiago Luís Infanger Serrano

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Effectiveness of dolutegravir-based vs boosted darunavir-based first-line 3-drug regimens in people with HIV with advanced disease: A trial emulation by Roberta Gagliardini, Andrea Giacomelli, Cristina Mussini, Stephen R. Cole, Jessie K. Edwards, Carmela Pinnetti, Alessandro Raimondi, Spinello Antinori, Silvia Nozza, Valentina Mazzotta, Giulia Carla Marchetti, Sergio Lo Caputo, Alessandro Tavelli, Antonella d'Arminio Monforte, Andrea Antinori, Alessandro Cozzi-Lepri

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A computational DNA methylation method to remove contaminated DNA from spent embryo culture medium for noninvasive preimplantation genetic testingResearch in context by Yidong Chen, Jin Huang, Fuchou Tang, Lu Wen, Jie Qiao

“…At the heart of ART success is preimplantation genetic testing (PGT), which enables the detection of chromosomal anomalies, single-gene disorders, and structural rearrangements, enhancing embryo selection and mitigating genetic risk. …”
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Assessing the foreign economic security of Ukraine by Yuliia Yehorova, Svitlana Chorna, Yuriy Petrushenko, Fedir Zhuravka, Khrystyna Potapenko, Iryna D’yakonova, Oksana Zamora

“…At the same time, the growth of foreign economic security is recorded in the period of stabilization during the implementation of structural reforms: 2005–2008 – the period after the Orange Revolution, 2014–2016 – the period of growth after the Revolution of Dignity, 2021 – post-pandemic recovery. …”
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Biomarker profile and disease burden associated with intermittent and long-term oral corticosteroid use in patients with severe asthma prior to biologic initiation in real-life (ST... by Florence Schleich, MD, PhD, Désirée Larenas-Linnemann, MD, FAAAAI, Dist.Intl.FACAAI, Alan Altraja, MD, PhD, Luis Pérez de Llano, MD, PhD, Konstantinos Kostikas, MD, PhD, FERS, Mohsen Sadatsafavi, MD, PhD, Arnaud Bourdin, MD, PhD, Roy Alton Pleasants, PharmD, Mark Hew, MBBS, PhD, FRACP, Wenjia Chen, PhD, Libardo Jiménez-Maldonado, MD, Simon Couillard, MD, MSc, Charlotte Suppli Ulrik, MD, DMSc, Adeeb A. Bulkhi, MD, MS, Ming-Ju Tsai, MD, PhD, George C. Christoff, MD, MPH, PhD, Nikolaos G. Papadopoulos, MD, PhD, FRCP, Paul E. Pfeffer, MRCP(UK), PhD, Dermot Ryan, MD, FRCGP, Celine Bergeron, MD, FRCPC, MSc, Mona S. Al-Ahmad, MD, FRCPC, Delbert R. Dorscheid, MD, PhD, Eileen Wang, MD, MPH, John D. Blakey, PhD, Belinda Cochrane, MBBS (Hons), MD, Matthew J. Peters, MD, PhD, Todor A. Popov, MD, PhD, Carlos A. Torres-Duque, MD, Susanne Hansen, PhD, Francesca Puggioni, MD, Kirsty Fletton, MBChB, Laila Salameh, PhD, Peter G. Middleton, MBBS, BSc(Med), PhD, FRACP, FERS, Paulo Márcio Pitrez, MD, PhD, Chin Kook Rhee, MD, PhD, Eve Denton, MBBS(Hons), MPH, PhD, FRACP, Kenneth R. Chapman, MSc, MD, FRCPC, FACP, FERS, Lauri Lehtimäki, MD, PhD, Ruth B. Murray, PhD, Chau-Chyun Sheu, MD, PhD, David J. Jackson, FRCP, PhD, Riyad Al-Lehebi, MD, FRCPC, Mariko Siyue Koh, MBBS, MRCP (UK), FCCP, Bassam Mahboub, MD, Ledit R.F. Ardusso, MD, Athena Gogali, MD, PhD, Giorgio Walter Canonica, MD, Piotr Kuna, MD, PhD, Martin Sivori, MD, PhD, Renaud Louis, MD, PhD, Shelley Abercromby, BSc(Hons), Giuseppe Guida, MD, PhD, Bernt Bøgvald Aarli, MD, PhD, Aaron Beastall, MSc, Victoria Carter, BSc, Ghislaine Scelo, PhD, John Townend, PhD, Borja G. Cosio, MD, PhD, Pujan H. Patel, MD, Celine Yun Yi Goh, MBBS, Zsuzsanna Csoma, MD, PhD, John W. Upham, MBBS, PhD, FRACP, João A. Fonseca, MD, PhD, Peter G. Gibson, MBBS, FRACP, Christine Jenkins, AM, MD, FRACP, Guy G. Brusselle, MD, PhD, Anne Chèvremont, Andréanne Côté, MD, MSc, FRCPC, Carlos Andrés Celis-Preciado, MD, MSc, Ivan Solarte, MD, MHPE, Celeste M. Porsbjerg, MD, PhD, Asger Sverrild, MD, PhD, Paula Kauppi, MD, PhD, Stelios Loukides, MD, FERS, Michael P. Makris, MD, PhD, Andriana I. Papaioannou, MD, PhD, Enrico Heffler, MD, PhD, Jeffrey Shi Kai Chan, MBChB, MPH, FESC, Hyonsoo Joo, MD, PhD, Liam G. Heaney, MD, Wei-Han Cheng, PhD, Njira Lugogo, MD, Michael E. Wechsler, MD, MMSc, Cláudia Chaves Loureiro, MD, PhD, Bellanid Rodríguez-Cáceres, BSc, Tatsuya Nagano, MD, PhD, Zhixiao Wang, PhD, Hao-Chien Wang, MD, PhD, Jorge Máspero, MD, Fernando Saldarini, MD, Ana María Stok, MD, Anahi Yañez, MD, Philip G. Bardin, PhD, Sinthia Z. Bosnic-Anticevich, PhD, Vidya Navaratnam, BMBS, MSc, PhD, Mohit Bhutani, MD, FRCPC, FCCP, M. Diane Lougheed, MSc, MD, FRCP(C), Lyle Melenka, MD, FRCP, B.MSc, Petros Bakakos, MD, Konstantinos P. Exarchos, MD, PhD, Aggelos A. Ladias, MD, Dóra Lúdvíksdóttir, MD, PhD, Takashi Iwanaga, MD, PhD, Elvia Angelica Contreras Contreras, MD, Sverre Lehmann, MD, PhD, José Alberto Ferreira, MD, Rebecca Gall, MD, Pin-Kuei Fu, MD, PhD, Diahn-Warng Perng, MD, PhD, Flavia Hoyte, MD, Rohit Katial, MD, Unnur S. Björnsdóttir, MD, Camille Taillé, MD, PhD, Christian Taube, MD, Breda Cushen, MD, PhD, Lakmini Bulathsinhala, MPH, Leif Bjermer, MD, PhD, David B. Price, FRCGP

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Implementation and Costs of an Agroforestry System in a Degraded Area of the Brazilian Semi-Arid Region by Israel Pereira de Quadro, Antônio Gilvan da Cruz de Souza, Danilo Batista Nogueira, Isac Gabriel Abrahão Bomfim, Aelton Biasi Giroldo

“…Specifically, we analyzed the system’s establishment process, estimated its costs, assessed structural development over time, and compared species performance and carbon accumulation across different biodiversity arrangements. …”
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Predicting HIV self-testing intentions among Chinese college students: a dual-model analysis integrating health belief constructs and machine learning prioritization by Yan Jiang, Jing Li, Jing Li, Jingfen Lu, Liping He, Lin Hu, Jiazhen He, Xianli Huang, Yuchao Li

“…Random forest modeling prioritized these psychological constructs (mean decrease Gini &gt;2.5), identifying male students and arts majors as critical subpopulations requiring targeted intervention.DiscussionOur dual-method analysis establishes that campus HIV control necessitates: 1) Gender-specific prevention programs addressing male students’ elevated risk exposure; 2) HBM-informed education strengthening self-efficacy and environmental cues; 3) Structural interventions reducing testing barriers through discreet service delivery. …”
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Interprofessional Differences in Multidimensional Self-Efficacy Associated With Professional Performance in Nephrology During Case-Based Learning by Chia-Ter Chao, Mei-Yi Wu, Kuan-Yu Hung, Mai-Szu Wu, Jyh-Chong Liang

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