Metabolism of tryptophan in non-small lung cancer patients with different effect of PD-1 / PD-L1 inhibitors immunotherapy by E. Yu. Zlatnik, A. B. Sagakyants, I. A. Novikova, A. Yu. Maksimov, O. P. Shatova, S. A. Appolonova, N. E. Moskaleva, S. A. Rumyantsev, A. V. Shestopalov

“…Introduction. In the structure of cancer incidence, lung cancer ranks first among men. …”
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Genetic diversity and phylogenetic relationship through the use of microsatellites in Gossypium hirsutum L. by Syeda Yashfeen Fatima, Tahira Luqman, Shabbir Hussain, Sahar Nadeem, Muhammad Kashif Riaz Khan, Allah Ditta, Muhammad Asif

“…Clustering based on molecular data classified the germplasm into three groups and measuring genetic distance through Euclidean distance while structure analysis revealed three gene-exchanging populations, representing a limited genetic basis in breeding programs. …”
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EPR study of interlayer interaction in Gd₂O₃/Fe nanostructure by A. M. Kasumov, A. I. Dmitriev, Yu. M. Bataiev, M. M. Bataiev, V. M. Karavaeva, K. A. Korotkov, A. I. Ievtushenko

“… In this work, a nanoscale structure consisting of contacting layers of a metal of the iron subgroup and a rare earth metal oxide (REM) is considered. …”
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ARGO: ARctic greenhouse Gas Observation metadata version 1 by J. Vogt, M. M. T. A. Pallandt, L. S. Basso, A. Bolek, K. Ivanova, M. Schlutow, G. Celis, M. Kuhn, M. Mauritz, E. A. G. Schuur, K. Arndt, A.-M. Virkkala, I. Wargowsky, M. Göckede

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Melanocortin 1 Receptor Regulates Pathological and Physiological Cardiac Remodeling by Anni Suominen, Aino Suni, Saku Ruohonen, Zoltán Szabó, Lotta Pohjolainen, Minying Cai, Eriika Savontaus, Virpi Talman, Risto Kerkelä, Petteri Rinne

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SGLT2 inhibitor upregulates myocardial genes for oxidative phosphorylation and fatty acid metabolism in Gαq-mice by Jordan M. Chambers, Dominique Croteau, David R. Pimentel, Adam C. Gower, Marcello Panagia, Tomas Baka, Fuzhong Qin, Ivan Luptak, Wilson S. Colucci

“…Conclusions: The SGLT2 inhibitor ERTU corrected the expression of myocardial gene programs for oxidative phosphorylation and fatty acid metabolism, and was associated with increased production of ATP, decreased release of mitochondrial ROS, and amelioration of the consequences of mitochondrial dysfunction on myocardial structure and function.…”
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Synthesis and transformation in the series of 2-((5-(2,4- and 3,4-dimethoxyphenyl)-3H-1,2,4-triazole-3-yl)thio)acetic acids by D. V. Dovbnia, A. H. Kaplaushenko, Yu. S. Frolova

“…Physical and chemical properties were investigated for the synthesized compounds. The structure of the obtained substances was confirmed by elemental analysis, IR-spectroscopy, 1H NMR-spectrometry, and their individuality were established by thin-layer chromatography. …”
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Delivering a Group-Based Quality of Life Intervention to Young Adult Cancer Survivors via a Web Platform: Feasibility Trial by Rina S Fox, Tara K Torres, Terry A Badger, Emmanuel Katsanis, DerShung Yang, Stacy D Sanford, David E Victorson, Betina Yanez, Frank J Penedo, Michael H Antoni, Laura B Oswald

“…Qualitative feedback identified needed revisions to the aesthetics (eg, images), content (eg, session titles), function (eg, clarity of functionality), and structure (eg, expandable sections), which were implemented. …”
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Ser/Thr phosphorylation of Mycobacterium tuberculosis type II RelK toxin by PknK destabilizes TA interaction and interferes with toxin neutralization by Shafinaz Rahman Sarah, Abhishek Garg, Sadiyah Afroz, Shaleen Korch, Arjun Ray, Amita Gupta, Vandana Malhotra

“…Results from molecular dynamics simulations, in vitro binding, and co-expression studies with RelJK proteins indicate that the secondary structure changes associated with Thr77 phosphorylation in RelK toxin compromise its binding to the RelJ antitoxin. …”
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Effectiveness of dolutegravir-based vs boosted darunavir-based first-line 3-drug regimens in people with HIV with advanced disease: A trial emulation by Roberta Gagliardini, Andrea Giacomelli, Cristina Mussini, Stephen R. Cole, Jessie K. Edwards, Carmela Pinnetti, Alessandro Raimondi, Spinello Antinori, Silvia Nozza, Valentina Mazzotta, Giulia Carla Marchetti, Sergio Lo Caputo, Alessandro Tavelli, Antonella d'Arminio Monforte, Andrea Antinori, Alessandro Cozzi-Lepri

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A case study of the development of a valid and pragmatic implementation science measure: the Barriers and Facilitators in Implementation of Task-Sharing Mental Health interventions... by Lawrence H. Yang, Judy K. Bass, PhuongThao D Le, Ritika Singh, Dristy Gurung, Paola R. Velasco, Margaux M. Grivel, Ezra Susser, Charles M. Cleland, Rubén Alvarado, Brandon A. Kohrt, Arvin Bhana

“…Results Continuous stakeholder involvement and concurrent pilot testing resulted in several adaptations of the BeFITS-MH measure’s structure, scaling, and format to enhance contextual relevance and utility. …”
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Water, Health, and Social Technologies: One Million Cisterns Programme Case Study by José Firmino de Sousa Filho, Walisson Angélico de Araújo, Mariana Sebastião, Adalton Fonseca, Raíza Tourinho, Denise Pimenta, Gervásio Santos, Lucas Emanuel, Roberto F. S. Andrade, Gustavo Casais, Gisele Paixão, Andrea Ferreira, Rachel Coelho, Maria Yuri Ichihara, Júlia Pescarini, Joanna M. N. Guimarães, Paulo Victor da Costa, Ismael Silveira, Rafael Silva, Rita Ribeiro, Maurício L. Barreto, On behalf of the SEDHI team

“…The DPSEEA framework evaluates the structural connections between climate change and human health. …”
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Ultrasound patterns of metastases from papillary thyroid cancer in soft tissues of the neck by V. S. Parshin, A. A. Veselova, P. D. Bespalov, V. V. Polkin, P. I. Garbuzov

“…The first pattern, including the depth-to-width ratio in the transverse scanning plane and the echo structure, has a sensitivity (Se) of 97 %, diagnostic accuracy (Ac) of 96.5 %, area under the curve (AUC) of 96 %, the probability ranges from 95 to 99 %. …”
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Emergence and evolution of rare ST592 blaNDM-1-positive carbapenem-resistant hypervirulent Klebsiella pneumoniae in China by Huan Zhang, Su Dong, Caiping Mao, Yuejuan Fang, Junjie Ying

“…Conjugation-related elements were predicted using oriTfinder. The plasmid structure was visualized using Circos, and a possible evolutionary model was constructed using BioRender.ResultsIsolates KPZM6 and KPZM16 were identified as ST592 and KL57, respectively, and were collected from the same department. …”
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Medical Marijuana Documentation Practices in Patient Electronic Health Records: Retrospective Observational Study Using Smart Data Elements and a Review of Medical Records by Donielle Beiler, Aanya Chopra, Christina M Gregor, Lorraine D Tusing, Apoorva M Pradhan, Katrina M Romagnoli, Chadd K Kraus, Brian J Piper, Eric A Wright, Vanessa Troiani

“…This absence of a formal data sharing structure necessitates tools aiding in consistent documentation practices to enable comprehensive patient care. …”
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595 Is PHASTR faster? A target trial emulation case study in the N3C by Steve Johnson, Carolyn Bramante, Til Stürmer, John Buse, Talia Wiggen, Jared Huling, Andrew Toler

“…The PHASTR contract structure helped produce high-quality results quickly by not only providing funding but also requiring a compressed timeline for a small team to focus on the study. …”
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Development and characterization of novel particleboard panels manufactured from organic waste with fiberglass reinforcement by Apri Heri Iswanto, Rio Febriansyah, Yusril Akmal Tanjung, Aryando Nainggolan, Nabila Nabila, Luthfi Hakim, Tito Sucipto, Jajang Sutiawan, Manggar Arum Aristri, Tomasz Rogoziński, Lee Seng Hua, Niken Subekti, Petar Antov

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Condições sociais de emergência de um subcampo esportivo: o caso do parkour (Social conditions of emergency of a sportive subfield: the case of parkour) (Condiciones sociales de... by Alessandra Vieira Fernandes, Vinicius Machado de Oliveira, Giuliano Gomes de Assis Pimentel, Juliano de Souza

“…In general, the development process of parkour evidences the influence of the mediatization of cultural goods and the incorporation of elements of the sports logic that have produced transformations in the structure of the modality and in the habitus of the agents. …”
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Diseño, validación y fiabilidad de un instrumento para analizar acciones técnico-tácticas en waterpolo (Design, validation, and reliability of an instrument to analyze technical-t... by Yurema Sabio Lago, Myriam Guerra Balic, Josep Solà Santesmases, Josep Cabedo Sanromà

“…In recent years the use of videos with analysis software has risen and the creation of these programs is believed to be necessary to analyze the internal structure of water polo. …”
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Text Message Intervention to Facilitate Secure Storage and Disposal of Prescription Opioids to Prevent Diversion and Misuse: Protocol for a Randomized Controlled Trial by Kathleen L Egan, Melissa J Cox, Donald W Helme, J Todd Jackson, Alice R Richman

“…This protocol represents the entire structure of the randomized controlled trial. …”
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