FOXA1 enhances antitumor immunity via repressing interferon-induced PD-L1 expression in nasopharyngeal carcinoma by Ying Liu, Bo Xiang, Wei Xiong, Pan Chen, Zhaoyang Zeng, Junshang Ge, Guiyuan Li, Mei Yi

“…Forkhead box A1 (FOXA1) is one of the earliest discovered pioneer factors, which can open up compact chromatin structures to facilitate the binding of other proteins to chromatin.Methods By using RNA sequencing, it was discovered that FOXA1 suppresses the activation of the interferon signaling pathway and the expression of the related interferon-responsive genes in NPC cells. …”
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A Comprehensive Resource for Exploring Antiphage Defense: DefenseFinder Webservice,Wiki and Databases by Tesson, Florian, Planel, Rémi, Egorov, Artyom A, Georjon, Héloïse, Vaysset, Hugo, Brancotte, Bryan, Néron, Bertrand, Mordret, Ernest, Atkinson, Gemma Catherine, Bernheim, Aude, Cury, Jean

“…Moreover, the rapid development of sequence-based predictions of structures offers novel possibilities of analysis and should be easily available. …”
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Determinants of Caregivers’ Ability to Accurately Detect Acute Malnutrition Using Color-Coded Mid-Upper Arm Circumference Tape and Pitting Edema by Benson C Singano, Collina A Tchongwe, Numeri C Geresomo, Tinna Ng’ong’ola-Manani, Aaron T Chikakuda, Alfred Ngwira, Stanley Mwase, Elsie Mawala, Benson Kazembe, Emma Budalla, Alexander A Kalimbira

“…Using a cascade model, community health workers (health surveillance assistants, n = 148) from 2 southern districts of Nsanje and Phalombe in Malawi, trained 12,057 caregivers of children aged 6 to 54 months in nutritional screening using color-coded MUAC tapes and pitting edema. Pretested structured questionnaires were used in face-to-face interviews with the caregivers to collect data on their age, marital status, education, district, occupation, and age of the child, which were predictor variables. …”
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A Cross-Sectional Study of Body Composition and Cardiorespiratory Fitness: Insights from Romanian Physical Education Male Students and Non-Professionals by Mădălina-Gabriela Coman, Alina Stan, Andreea Maria Adam, Carmen Gheorghe, Carmen Pârvu, Corneliu Mircea Codreanu, Liviu Moraru, Daniel-Andrei Iordan, Ilie Onu

“…The significantly higher body fat and lower cardiovascular capacity in MSNP students highlight the urgent need for targeted physical activity interventions and nutritional education to mitigate obesity risk. Integrating structured exercise programs and lifestyle modifications into university curricula could enhance long-term metabolic health outcomes in young adults…”
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International society of liquid biopsy (ISLB) perspective on minimal requirements for ctDNA testing in solid tumors by Nicola Fusco, Konstantinos Venetis, Francesco Pepe, Omshree Shetty, Silvia Calabuig Farinas, Simon Heeke, Julia V. Burnier, Simon J. Patton, Ellen Heitzer, Giovanni Nigita, Paul Hofman, Maria Jose Serrano, Massimo Cristofanilli, Eloisa Jantus-Lewintre, David R. Gandara, Christian Rolfo, Umberto Malapelle

“…Through initiatives led by the Quality Control and Accreditation Committee, educational programs, and multidisciplinary stakeholder workshops, ISLB provides a structured framework to promote standardization and foster innovation. …”
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Aberrant EZHIP expression drives tumorigenesis in osteosarcoma by Wajih Jawhar, Geoffroy Danieau, Alva Annett, Takeaki Ishii, Andrea Bajic, Ana Castillo-Orozco, Brian Krug, Yara Faucher-Jabado, Justin Seyedmoomenkashi, Mostafa Saquib, Masoumeh Aghababazadeh, Marjan Khatami, Nadim Tawil, Damien Faury, Sungmi Jung, Ahmed Aoude, Robert E. Turcotte, Benjamin Ellezam, Thomas Sontag, Sylvie Langlois, Daniel Sinnett, Swneke D. Bailey, Lingxin Zhang, Dorothée Dal Soglio, Claudia L. Kleinman, Nada Jabado, Livia Garzia

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The utility of combining deep learning with metabarcoding to model biodiversity dynamics at a national scale by Adrian Baggström, Robert Goodsell, Laura van Dijk, Ela Iwaszkiewicz-Eggebrecht, Andreia Miraldo, Ayco J.M. Tack, Tobias Andermann

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Virtual Intervention for Vertebral frActures (VIVA): protocol for a feasibility study of a multicentre randomized controlled trial by Ada Sevinc, Alexandra Papaioannou, Suzanne N. Morin, Jennifer A. Watt, Raheem B. Kherani, Sheila Brien, Larry Funnell, Lehana Thabane, Lauren A. Beaupre, Jenna C. Gibbs, Heather Keller, Caitlin McArthur, Matteo Ponzano, Sonia Singh, Sharon Straus, Jenny Thain, Zachary J. Weston, Timothy H. Wideman, Christopher D. Witiw, Lora Giangregorio

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Fu’s subcutaneous needling facilitates muscle repair by regulating mitochondrial homeostasis in rat with chronic peripheral nervous pain by Po-En Chiu, Po-En Chiu, Zhonghua Fu, Zhonghua Fu, Hung-Chuan Pan, Hung-Chuan Pan, Hung-Chuan Pan, Hung-Chuan Pan, Yi-Ching Tsai, Chia-Yun Tsai, Wei-Jen Hsu, Li-Wei Chou, Li-Wei Chou, Li-Wei Chou, De-Wei Lai, De-Wei Lai

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Health provider perspectives on differentiated service delivery for HIV in Oyo state, Nigeria: exploring the experiences of service providers from a demand perspective by Adelaja Modupe Gift, Folahanmi Tomiwa Akinsolu, Olunike Rebecca Abodunrin, Akim Tafadzwa Lukwa, Mobolaji Timothy Olagunju, Adekemi Akinpelu, Ogunwale Mercy Mary, Ola Oluwabukola Mary, Dolapo Omotayo Raji, Lilian Ogochukwu Ezechi, Aisha Oluwaseun Gambari, Oliver Chukwujekwu Ezechi

“…However, their success depends on addressing structural and operational challenges, tailoring approaches to local contexts, and strengthening health workforce capacity. …”
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Post-conflict nutritional status of school-age children in North Wollo zone, Northeast Ethiopia: a multi-center cross-sectional study by Zelalem Dejazmach, Birtukan Gizachew Ayal, Woldeteklehaymanot Kassahun, Getinet Kumie, Muluemebet Kassa, Berihun Mulu Yayeh, Seada Seid Ahmed, Abebe Worku Gela, Habtu Debash, Selamawit Ayalew, Asmamaw Ameshe, Abebaw Alamrew, Mulu Shiferaw Asfaw, Sefineh Fenta feleke, Melese Abate Reta

“…Socio-demographic data was collected through a structured questionnaire, and anthropometric measurements were transformed into indices using the World Health Organization’s Anthro-software. …”
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The contribution of personalized video feedback to robotic partial nephrectomy training in realistic 3D tumor kidney models: design, production and implementation by Ahmet Furkan Sarıkaya, Kayhan Tarım, Ersin Köseoğlu, Arif Özkan, İbrahim Can Aykanat, Baris Esen, Umut Can Karaarslan, Mustafa Müdüroğlu, Şevval Kanlı, Murat Can Kiremit, Yakup Kordan, Mevlana Derya Balbay, Tarık Esen, Serdar Aydın, Serdar Aydın, Abdullah Erdem Canda, Abdullah Erdem Canda

“…This suggests that structured preparatory training with objective performance targets can enhance learning outcomes in surgical simulation. …”
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Early findings from the integration of hypertension care into differentiated service delivery models for HIV in Uganda: a mixed‐method study by John Baptist Kiggundu, Fred C. Semitala, Chelsea Faith Lipoto, Lilian Giibwa, Robert Twine, Savio Mwaka, Florence Ayebare, Christine Kiwala, Evelyn N. Magambo, Gerald Mutungi, Isaac Ssinabulya, Donna Spiegelman, James Kayima, Martin Muddu, Jeremy I. Schwartz, Anne R. Katahoire, Chris T. Longenecker

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The novel BET‐CBP/p300 dual inhibitor NEO2734 is active in SPOP mutant and wild‐type prostate cancer by Yuqian Yan, Jian Ma, Dejie Wang, Dong Lin, Xiaodong Pang, Shangqian Wang, Yu Zhao, Lei Shi, Hui Xue, Yunqian Pan, Jun Zhang, Claes Wahlestedt, Francis J Giles, Yu Chen, Martin E Gleave, Collin C Collins, Dingwei Ye, Yuzhuo Wang, Haojie Huang

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The issue of credibility between customers’ perceptions and the attitude toward Facebook advertising by Jassim Al-Gasawneh, Abdullah AlSokkar, Mahmoud Alghizzawi, Tahreer Abu Hmeidan, Deemah Alarabiat, Ahmed Alamro

“…This sample was chosen due to students’ high engagement with social media and their relevance as future marketing professionals, yielding 277 valid responses to be analyzed, and the hypotheses were tested using smart PLS through Structural Equation Modelling. The analysis revealed that Perceived Interactivity, Advertising Avoidance, and Privacy positively impacted attitudes towards Facebook advertisements, with coefficients and significance levels as follows: β = 0.122, t = 5.545, p < 0.003, β = 0.324, t = 2.643, p < 0.002, and β = 0.046, t = 3.833, p < 0.003, respectively. …”
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High-quality bonds: serine acetyltransferase 2 gene revealed by GWAS is associated with grain protein content in spring durum wheat by Aleksey Ermolaev, Ludmila Bespalova, Varvara Korobkova, Aleksey Yanovsky, Lubov Nazarova, Aleksandra Kroupina, Anastasia Chernook, Aleksandra Mudrova, Viktoria Voronezhskaya, Viktoria Voronezhskaya, Pavel Kroupin, Gennady Karlov, Mikhail Divashuk, Mikhail Divashuk

“…A missense mutation (Gly325Ser) in the ninth exon of sat2 was associated with a 1.33% GPC increase in spring durum wheat recombinant inbred lines. Structural analysis indicated that the Gly325Ser mutation alters the SAT2 protein’s C-terminal α-helix, potentially influencing enzyme activity. …”
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Synthesis, biological investigation, and in silico studies of 2-aminothiazole sulfonamide derivatives as potential antioxidants by Apilak Worachartcheewan, Ratchanok Pingaew, Veda Prachayasittikul, Setthawut Apiraksattayakul, Supaluk Prachayasittikul, Somsak Ruchirawat, Virapong Prachayasittikul

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In silico screening of naturally derived dietary compounds as potential butyrylcholinesterase inhibitors for Alzheimer’s disease treatment by Md. Tarikul Islam, Md. Aktaruzzaman, Chandan Barai, Farhan Ishrak Rafi, Al Riyad Hasan, Tasfiah Tasnim, Parvej Sarder, Ghadeer M. Albadrani, Muath Q. Al-Ghadi, Amany A. Sayed, Mohamed M. Abdel-Daim, Humayra Afroz Dona, Kishore Kumar Sarkar, Md. Obayed Raihan

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Cuidar de pessoas transexuais na ótica dos residentes de enfermagem [Care for transgender people from the nursing resident’s perspective] [Cuidar de personas transexuales en la ópt... by Julia Sousa Martins de Almeida, Elizabeth Rose Costa Martins, Cristiane Maria Amorim Costa, Paula Costa de Moraes, Gabriela Dandara Fernandes Ferreira, Thelma Spindola

“…Method: an exploratory, qualitative, descriptive study was conducted in 2017, in the urology unit of a university hospital Rio de Janeiro city, by semi-structured interview of 13 first- and second-year nursing residents of the clinical surgery program. …”
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FACTORS ASSOCIATED WITH ANXIETY AND DEPRESSION SPECTRUM DISORDERS IN BEHCHET’S DISEASE by P. S. Ovcharov, T. A. Lisitsyna, D. Yu. Veltishchev, O. F. Seravina, O. B. Kovalevskaya, S. I. Glukhova, Z. S. Alekberova, E. L. Nasonov

“…ADSDs were diagnosed by a psychiatrist according to the ICD-10 during semi-structured interviews using the Hospital Anxiety and Depression Scale (HADS), the Hamilton Anxiety Rating Scale (HAM-A), and the Montgomery-Asberg Depression Rating Scale (MADRS). …”
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