Spontaneous and activation-induced apoptosis of peripheral blood mononuclear cells in the pathogenesis of type 1 diabetes mellitus by A. V. Lugovaya, N. M. Kalinina, V. Ph. Mitreikin, Yu. V. Emanuel, Yu. P. Kovalchuk, A. V. Artyomova

“…The key point in the T1DM initiation is apoptosis resistance of activated autoreactive T lymphocytes, that migrate from bloodstream to the pancreas and take an active part in destruction of the pancreatic insular structures. Despite long studies of T1DM pathogenesis, the exact causes of resistance of effector T cell clones to apoptosis remain unclear. …”
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Anthracite nanoporous carbons obtained by nitric acid intercalation followed by alkaline activation by V. O. Kucherenko, Yu. V. Tamarkina, V. O. Sabierova, M. M. Nechitaylov

“… The aim of the work is to determine the effect of nitric acid intercalation of anthracite on the porous structure and adsorption properties of activated carbons (ACs) obtained by alkaline activation. …”
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Apoptotic extracellular vesicles derived from human dental pulp stem cells facilitate periodontal tissue regeneration by Junyi Xia, Zeyu Zhang, Jinlong Weng, Guanxiong Zhu, Zidan Xu, Liting Zeng, Janak Lal Pathak, Lina Yu

“…Abstract Objective Apoptotic extracellular vesicles (ApoEVs) derived from human dental pulp stem cells (hDPSCs) are subcellular structures released during programmed cell death. These vesicles carry rich biological information and regulatory potential, and have demonstrated significance in regulating cell behavior and tissue repair. …”
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Severe menopausal symptoms and associated factors among post-menopausal women in Ambo town, West Shewa, Ethiopia: a cross-sectional study by Galana Takele Namara, Binyam Seifu Woldeyes, Dereje Yadesa Irenso, Daniel Belema Fekene, Gizachew Abdissa Bulto, Musa Abduro Fata, Warkitu Sileshi Ensermu, Amare Tesfaye Yami

“…Data were collected using a structured, interviewer-administered questionnaire. …”
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Trapped by debt: an ethnographic study of medical indebtedness and hospital detention in the Fundong Health District, Cameroon by Ashangwa Constantine Tanywe, Ashangwa Constantine Tanywe, Ngambouk Vitalis Pemunta, Ngambouk Vitalis Pemunta, Vidarah Nimar, Cybel Nji Angwe, Mathias Alubafi Fubah, Mathias Alubafi Fubah, Maurine Ekun Nyok, Tom Obara Bosire, Nguyen Ngoc Bich Tram, Brendabell Ebanga Njee, Womma Habiba Hira

“…BackgroundThis study investigates the structural and socio-cultural drivers of medical indebtedness and hospital detention due to unpaid healthcare bills in the Fundong Health District, Cameroon. …”
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Magnetic Field of a Ring-like Molecular Cloud by Dana Alina, Adel Umirbayeva, Yasuo Doi, Soichiro Jo, Yue Hu, Alex Lazarian, Janik Karoly, Tie Liu, Koji S. Kawabata, Alua Mukhash, Danial Zhumagayir, Tomori Hori, Tetsuharu Maruta, Ryo Imazawa, Tatsuya Nakaoka, Mahito Sasada

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Discovery of Cyclopentane-Based Phospholipids as Miltefosine Analogs with Superior Potency and Enhanced Selectivity Against <i>Naegleria fowleri</i> by Ahmed H. E. Hassan, Hương Giang Lê, Tuấn Cường Võ, Minji Kim, Joo Hwan No, Mohamed H. Aboutaleb, Jaehoon Sim, Byoung-Kuk Na, Yong Sup Lee

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<i>Escherichia coli</i> in Brazilian Poultry Fecal Samples: Co-Carriage of Fosfomycin and ESBL Resistance by Felipe Juscele, Andre B. S. Saidenberg, Lars E. B. Christoffersen, Sofie M. Edslev, Søren Hallstrøm, Jessica R. Nacarato, Fernanda B. Barbosa, Marcos P. Cunha, Fernanda Esposito, Nilton H. Lincopan, Marc Stegger, Terezinha Knöbl

“…Comparative genomic analysis of 133,541 global <i>E. coli</i> genomes from EnteroBase showed that 35% harbored similar transposon structures, with 2% carrying <i>fosA3</i>. These <i>fosA3</i>-positive isolates were significantly associated with South America and exhibited high co-carriage of ESBL genes, particularly in environmental and poultry-associated isolates. …”
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THE ARTISTIC POTENTIAL OF CHORAL CONDUCTING IN CONTEMPORARY UKRAINE by Lyudmyla SHUMSKA, Yuliia PUCHKO-KOLESNYK, Lyudmyla KOSTENKO, Oleksandr VILA-BOTSMAN, Olha MARTYNOVSKA

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Cartilage loss is greater in knees with virtual joint replacement status than in matched controls without by Felix Eckstein, Wolfgang Wirth, Ali Guermazi, Frank Roemer, Michael Nevitt, Christoph Ladel, Leena Sharma, David J. Hunter, C. Kent Kwoh

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Parental Phasing Study Identified Lineage-Specific Variants Associated with Gene Expression and Epigenetic Modifications in European–Chinese Hybrid Pigs by Chenyu Li, Mei Ge, Keren Long, Ziyin Han, Jing Li, Mingzhou Li, Zhiyan Zhang

“…In this study, we established three crossbred pig families derived from distant genetic lineages and systematically identified variants from different lineages, including single nucleotide polymorphisms (SNPs) and structural variations (SVs). At the phase level, we quantitatively analyzed gene expression, four histone modifications (H3K4me3, H3K27ac, H3K4me1, and H3K27me3), and the binding strength of transcription factor (CTCF) in backfat (BF) and longissimus dorsi (LD) muscle. …”
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Medium-Chain Acyl-CoA Deficiency: Outlines from Newborn Screening, In Silico Predictions, and Molecular Studies by Serena Catarzi, Anna Caciotti, Janita Thusberg, Rodolfo Tonin, Sabrina Malvagia, Giancarlo la Marca, Elisabetta Pasquini, Catia Cavicchi, Lorenzo Ferri, Maria A. Donati, Federico Baronio, Renzo Guerrini, Sean D. Mooney, Amelia Morrone

“…Bioinformatics predictions based on both phylogenetic conservation and functional/structural software were used to characterize the new identified variants. …”
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Antimicrobial resistance in a protracted war setting: a review of the literature from Palestine by Ramya Kumar, Osama Tanous, David Mills, Bram Wispelwey, Yara Asi, Weeam Hammoudeh, Omar Dewachi

“…Notably, most studies attributed AMR to local practices, often overlooking broader structural and socio-political drivers. This review underscores the need to contextualize AMR within the environment, particularly under conditions of sustained warfare.IMPORTANCEThis study goes beyond merely reviewing and summarizing data on AMR in the occupied Palestinian territories (oPt), a region enduring chronic war-like conditions. …”
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Why do older adults hesitate to get the flu vaccine? A cross-sectional study on vaccine hesitancy in the post-COVID-19 era by Xinyue Wang, Sanmei Wen, Jiaqian Wu, Ziyi Cui, Hong Shen, Shiyao Hu, Shujun Zeng, Yan Tang

“…Multinomial logistic regression models were used to identify predictors of vaccine hesitancy, adjusting for sociodemographic variables, self-reported health status and self-report vaccination experiences. Structural equation modeling (SEM) was employed to examine the underlying factors contributing to vaccine hesitancy and quantify their interrelationships.ResultsA high proportion (85.2%) of participants exhibited influenza vaccine hesitancy, with 16.2% being complete refusers. …”
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Distribution of variants of the <i>TNFA</i> gene regulatory sites among Russian women of Caucasian origin with leiomyoma by V. I. Konenkov, A. V. Shevchenko, V. F. Prokofiev, E. G. Koroleva

“…The aim of our research was to analyze the distribution of TNF-238, TNF- 308 and TNF-863 structural variants at the regulatory region of the TNFA gene in a representative group of Caucasian patients with UF compared with a matched group of healthy women followed by assessment of personalized prognostic significance of suggested differences. 180 patients diagnosed with uterine fibroids and 98 practically healthy women were examined. …”
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The impact of lifestyle sports on the sleep quality of depressed high school students in Jiangsu Province, China: based on cross-sectional study by Xianghe Chen, Yuxin Yang, Jianbo Hu, Shengjie Jin, Pengcheng Lu, Xinyu Zeng, Xiaoyan Yi, Rongbin Yin, Chenghao Zhong

“…The mediation model of depression between lifestyle sports and sleep quality was constructed via the Model4 model and other models in the SPSS macro program Process4.0. From the 32,974 valid questionnaires, 14,943 depressed high school students (SDS ≥ 53) were screened out, and structural equation modeling of the relationships between the six dimensions of lifestyle sports and the sleep quality of depressed high school students has been established via AMOS 28.0. …”
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A rural practice affinity model: recognizing the role of emergency medicine competency by Eliseo Orrantia, Theresa Kline, Lindsay Nutbrown, Erin Cameron, Margaret Cousins

“…A partial correlation matrix between the variables of interest (general self-efficacy, emergency medicine competency, rural practice self-efficacy, and rural practice intentions) - controlling for the effects of relationships, financial aspects, personal aspects, and social desirability - was created and subjected to a structural equation model. Results: Our initial rural practice affinity model resulted in a poor fit of the model to the data. …”
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Strengthening health system's capacity for pre-exposure prophylaxis for adolescent girls and young women and adolescent boys and young men in South Africa (SHeS'Cap-PrEP): Protocol... by Edward Nicol, Trisha Ramraj, Mbuzeleni Hlongwa, Wisdom Basera, Ngcwalisa Jama, Carl Lombard, Tracy McClinton-Appollis, Darshini Govindasamy, Desiree Pass, Noluntu Funani, Sarah Aheron, Ariana Paredes-Vincent, Jennifer Drummond, Mireille Cheyip, Sibongile Dladla, Jason Bedford, Cathy Mathews

“…In South Africa, various approaches of delivering PrEP have been adopted at different service delivery points (facility-based only, school-based only, community-based only and hybrid school-facility and community-facility models) to overcome challenges associated with individual, structural, and health systems related barriers that may hinder access to and uptake of PrEP among these populations. …”
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Cultural and behavioral drivers of zoonotic disease transmission and persistence among diverse pastoralist communities in East Africa by Dismas C.O. Oketch, Ruth Njoroge, Tonny O. Ngage, Asha Abdikadir Omar, Abdulai Magarre, Raphael Pasha, John Gachohi, Samuel Waiguru Muriuki, Samoel Ashimosi Khamadi, Ali Duba Boru, Boku Bodha, Lydia Kilowua, Nazaria Wanja Nyaga, Humphrey Kariuki Njaanake, Eunice Kamaara, Walter Jaoko, M. Kariuki Njenga, Eric Osoro, Dalmas Omia

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Perceptions regarding rabies prevention and control in two different community settings in Vietnam using a Q-sorting approach by Doan Hoang Phu, Trang Phuong Thao, Mai Duong Tieu, Dung Nguyen Thi Thuy, Trang Nguyen Thi Phuong, Pawin Padungtod, Dinh Bao Truong

“…Although awareness of rabies is high, structural limitations – particularly inadequate access to veterinary services – hinder effective control. …”
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