Ultrasound Phenotype-Based Approach to Treatment Choice in Osteoarthritis by Rositsa Karalilova, Velichka Popova, Konstantin Batalov, Dimitar Kolev, Lyatif Kodzhaahmed, Dimitrina Petrova-Stoyankova, Nikola Tepeliev, Tsvetelina Kostova, Lili Mekenyan, Zguro Batalov

“…<b>Introduction/Objectives:</b> Osteoarthritis (OA) is a chronic systemic disease that affects the entire array of joint structures. It is one of the most common chronic, socially significant diseases, associated with a decline in the quality of life of patients and constantly increasing the cost of treatment. …”
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Dynamics and Trends in the Incidence of Rabies in the Russian Federation and some Adjacent Regions of Eurasia in 2013–2021 by O. N. Zaykova, M. A. Losich, E. V. Rusakova, O. A. Verkhovsky, A. A. Shabeykin, T. V. Grebennikova

“…As a result, the proportion of dogs and cats in the morbidity structure has significantly increased, which, given their proximity to humans, ensures the maintenance of a high level of epidemiological risk. …”
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Integrated multi-omics profiling reveals the role of the DNA methylation landscape in shaping biological heterogeneity and clinical behaviour of metastatic melanoma by Andrea Anichini, Francesca P. Caruso, Vincenzo Lagano, Teresa M. R. Noviello, Rossella Tufano, Gabriella Nicolini, Alessandra Molla, Ilaria Bersani, Francesco Sgambelluri, Alessia Covre, Maria F. Lofiego, Sandra Coral, Anna Maria Di Giacomo, Elena Simonetti, Barbara Valeri, Mara Cossa, Filippo Ugolini, Sara Simi, Daniela Massi, Massimo Milione, Andrea Maurichi, Roberto Patuzzo, Mario Santinami, Michele Maio, Michele Ceccarelli, Roberta Mortarini, On behalf of the EPigenetic Immune-oncology Consortium Airc (EPICA) investigators

“…Abstract Background We developed an integrated multi-omics analysis in metastatic melanoma (MM) cohorts to associate DNA methylation profiles with tumor progression, survival, response to adjuvant immunotherapy, structure of the tumor immune microenvironment and transcriptional programs of immunity and melanoma differentiation. …”
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Multiomics analysis reveals signatures of selection and loci associated with complex traits in pigs by Lei Liu, Guoqiang Yi, Yilong Yao, Yuwen Liu, Jiang Li, Yalan Yang, Mei Liu, Lingzhao Fang, Delin Mo, Longchao Zhang, Yonggang Liu, Yongchao Niu, Liyuan Wang, Xiaolu Qu, Zhangyuan Pan, Lei Wang, Muya Chen, Xinhao Fan, Yun Chen, Yongsheng Zhang, Xingzheng Li, Zhen Wang, Yijie Tang, Hetian Huang, Pengxiang Yuan, Yuying Liao, Xinjian Li, Zongjun Yin, Di Liu, Dongjie Zhang, Quanyong Zhou, Wangjun Wu, Jicai Jiang, Yahui Gao, George E. Liu, Lixian Wang, Yaosheng Chen, Kui Li, Martien A. M. Groenen, Zhonglin Tang

“…Using nine genomes—seven of which were newly generated, high‐quality de novo assembled genomes—and 1081 resequencing genomes, we built a pan‐genome and identified 134.24 Mb nonredundant nonreference sequences, 1099 novel protein‐coding genes, 187,927 structural variations (SVs) and 30,143,962 single‐nucleotide polymorphisms (SNPs). …”
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Extracellular acyl-CoA-binding protein as an independent biomarker of COVID-19 disease severity by Stephane Isnard, Stephane Isnard, Tsoarello Mabanga, Tsoarello Mabanga, Léna Royston, Léna Royston, Léna Royston, Carolina A. Berini, Carolina A. Berini, Simeng Bu, Simeng Bu, Orthy Aiyana, Orthy Aiyana, Hansen Feng, Hansen Feng, Bertrand Lebouché, Bertrand Lebouché, Bertrand Lebouché, Bertrand Lebouché, Cecilia T. Costiniuk, Cecilia T. Costiniuk, Joseph Cox, Joseph Cox, Guido Kroemer, Guido Kroemer, Guido Kroemer, Madeleine Durand, Jean-Pierre Routy, Jean-Pierre Routy, Jean-Pierre Routy, the Biobanque Québécoise de la COVID-19 (BQC-19)

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The application of blockchain with a comparative approach and its impact on risk, flexibility and internal control evaluation by mohammadsadegh aminipoor, HamidReza GholamniaRoshan, azadeh kiapour, Iman Dadashi

“…Blockchain is essentially a public ledger, where groups of transactions or events are recorded and stored in a chain-like data structure; this approach creates a fast yet secure way to transfer funds. …”
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How do individuals with mental health disorder and spinal cord injury gain access to participate in voluntary sport groups in Switzerland? by Florence Epiney, Siegfried Nagel, Christopher Klenk

“…The coaches’ point of view was included to have a complementary perspective compared to the athletes to produce comprehensive insights. A semi-structured interview guideline was developed, discussed with experts and tested in a pilot interview (Braun & Clarke, 2022; Smith & Sparkes, 2020). …”
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Perbandingan Penggunaan Katalis Alam (Zeolit dan Bentonit) dalam Sintesis Biodiesel dari Minyak Goreng Komersil by Nila Tanyela Berghuis, Mutaqqin Mutaqqin, Farid Imam Hidayat, Sugianto Sugianto, Harbi Pratama, Anggun Kirana, David Aji Rifaldi, Abelia Jesica, Paradigma Maulana, Afif Thufail

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Mannich Base Derived from Lawsone Inhibits PKM2 and Induces Neoplastic Cell Death by Lucas Rubini-Dias, Tácio V. A. Fernandes, Michele P. de Souza, Déborah Hottz, Afonso T. Arruda, Amanda de A. Borges, Gabriel Ouverney, Fernando de C. da Silva, Luana da S. M. Forezi, Gabriel Limaverde-Sousa, Bruno K. Robbs

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A computational DNA methylation method to remove contaminated DNA from spent embryo culture medium for noninvasive preimplantation genetic testingResearch in context by Yidong Chen, Jin Huang, Fuchou Tang, Lu Wen, Jie Qiao

“…At the heart of ART success is preimplantation genetic testing (PGT), which enables the detection of chromosomal anomalies, single-gene disorders, and structural rearrangements, enhancing embryo selection and mitigating genetic risk. …”
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MSA-3D: Dissecting Galaxies at z ∼ 1 with High Spatial and Spectral Resolution by Ivana Barišić, Tucker Jones, Kris Mortensen, Themiya Nanayakkara, Yuguang Chen, Ryan Sanders, James S. Bullock, Kevin Bundy, Claude-André Faucher-Giguère, Karl Glazebrook, Alaina Henry, Mengting Ju, Matthew Malkan, Takahiro Morishita, Danail Obreschkow, Namrata Roy, Juan M. Espejo Salcedo, Alice E. Shapley, Tommaso Treu, Xin Wang, Kyle B. Westfall

“…Here we describe the multiplexed slit-stepping method, which is >15 times more efficient than the NIRSpec IFS mode for our program. As an example of the data quality, we present a case study of an individual galaxy at z = 1.104 (stellar mass M _* = 10 ^10.3 M _⊙ , star formation rate, SFR = 3 M _⊙ yr ^−1 ) with prominent face-on spiral structure. …”
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Dynamics of turnover of sugar-lowering drugs in the retail segment of the pharmaceutical market from 2020 to 2024 by D. V. Kurkin, E. V. Makarova, V. I. Zvereva, A. R. Makarova, D. A. Bakulin, O. V. Marincheva, Yu. V. Gorbunova, Yu. A. Kolosov, I. S. Krysanov, K. N. Koryanova, D. A. Galkina, N. A. Osadchenko, R. V. Drai, I. E. Makarenko, A. S. Shuvaeva

“…Despite maintaining the leading position of metformin, the consumption structure is shifting towards more expensive schemes. …”
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Propuesta metodológica para la enseñanza de la biomedicina orientada a las herramientas de detección y diagnóstico molecular para estudiantes de Medicina by Gabriela Naranjo, Carolina Tituaña-Puente, Camila Maldonado, Daniela Alejandra Velasco-Uquillas, Grecia Victoria Vivas-Colmenares, José Rubén Ramírez-Iglesias

“…Methods: The proposed structure is based on the requirements of basic science subjects that students must complete to understand molecular diagnostics. …”
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Synergistic Effects of BaTiO₃ and MFe₂O₄ (M = Mn, Ni, Cu, Zn, and Co) Nanoparticles as Artificial Pinning Centers on the Performance of YBa<sub>2</... by Amjad S. Dair, Yassine Slimani, Essia Hannachi, Faten Ben Azzouz, Munirah A. Almessiere

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Relationship between prenatal anxiety, depression, pregnancy stress and their social determinants by Weicui Meng, Sufeila Shalayiding, Xiaoting Wang, Bahedana Sailike, Ting Jiang

“…Given that psychological problems during pregnancy may lead to short-term and long-term adverse outcomes for both mothers and infants, clarifying their network structure and core social determinants holds important public health significance for formulating regional intervention strategies. …”
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Evaluating snow depth retrievals from Sentinel-1 volume scattering over NASA SnowEx sites by Z. Hoppinen, Z. Hoppinen, R. T. Palomaki, G. Brencher, D. Dunmire, D. Dunmire, E. Gagliano, A. Marziliano, J. Tarricone, J. Tarricone, H.-P. Marshall

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A multi-omics reciprocal analysis for characterization of bacterial metabolism by Gabriel Santos Arini, Gabriel Santos Arini, Gabriel Santos Arini, Tiago Cabral Borelli, Tiago Cabral Borelli, Tiago Cabral Borelli, Elthon Góis Ferreira, Rafael de Felício, Paula Rezende-Teixeira, Matheus Pedrino, Matheus Pedrino, Franciene Rabiço, Franciene Rabiço, Guilherme Marcelino Viana de Siqueira, Guilherme Marcelino Viana de Siqueira, Luiz Gabriel Mencucini, Luiz Gabriel Mencucini, Henrique Tsuji, Henrique Tsuji, Lucas Sousa Neves Andrade, Leandro Maza Garrido, Gabriel Padilla, Alberto Gil-de-la-Fuente, Alberto Gil-de-la-Fuente, Mingxun Wang, Norberto Peporine Lopes, Daniela Barretto Barbosa Trivella, Letícia Veras Costa-Lotufo, María-Eugenia Guazzaroni, Ricardo Roberto da Silva, Ricardo Roberto da Silva, Ricardo Roberto da Silva

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Psychometric evaluation of EQ-5D-5L in OHCA survivors from the TTM2 trial: a post hoc analysis by Mattias Bohm, Kristofer Årestedt, Susann Ullén, Niklas Nielsen, Josef Dankiewicz, Hans Friberg, Erik Blennow Nordström, Alain Cariou, Janus Christian Jakobsen, Anders Morten Grejs, Matthias Haenggi, Naomi E. Hammond, Katarina Heimburg, Thomas R. Keeble, Christoph Leithner, Christian Rylander, Johan Undén, Matt P. Wise, Tobias Cronberg, Gisela Lilja

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Phase formation, microstructural and superconducting properties of YBCO added Ca-compounds extraction eggshells by Siew Hong Yap, Mohd Mustafa Awang Kechik, Syahrul Humaidi, Khairul Khaizi Mohd Shariff, Hussien Baqiah, Soo Kien Chen, Kean Pah Lim, Mohd Hafiz Mohd Zaid, Yazid Yaakob, Mohd Khalis Abdul Karim, Zainal Abidin Talib, Zhi Wei Loh, Aliah Nursyahirah Kamarudin, Abdul Halim Shaari, Muralidhar Miryala

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Comparative transcriptome analysis reveals molecular mechanisms of resistance in Chinese cabbage to Plasmodiophora brassicae pathotype 11 by Yue Qiu, Yue Qiu, Yue Qiu, Jinhao Zhang, Jinhao Zhang, Chunju Deng, Chunju Deng, Jiasheng Yuan, Jiasheng Yuan, Bowen Wang, Bowen Wang, Han Meng, Han Meng, Mohamed Mohany, Liting Zeng, Liting Zeng, Lanfang Wei, Lanfang Wei, Waqar Ahmed, Guanghai Ji, Guanghai Ji

“…Microscopic analysis at 21 dai revealed that the resistant cultivar (JP) root structure remained largely unaffected, while the roots of the susceptible cultivar (83-1) exhibited significant tissue distortion and gall formation, underscoring the effectiveness of the resistance mechanisms. …”
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