Accessing a New Population of Supermassive Black Holes with Extensions to the Event Horizon Telescope by Xinyue Alice Zhang, Angelo Ricarte, Dominic W. Pesce, Michael D. Johnson, Neil Nagar, Ramesh Narayan, Venkatessh Ramakrishnan, Sheperd Doeleman, Daniel C. M. Palumbo

“…We find that the linearly polarized structure evolves substantially with the Eddington ratio, with greater evolution at larger inclinations, complicating potential spin inferences for inclined sources. …”
Get full text

UJI AKTIVITAS ANTIOKSIDAN PADA MODIFIKASI SENYAWA KHRISIN DENGAN GUGUS ALKOKSI MENGGUNAKAN METODE RECIFE MODEL 1 (RM1) by FK Nisa, Kasmui Kasmui, Harjito Harjito

“…Dipole moment, binding energy and electronic energy used for Quantitative Structure-Activity QSAR analysis. The result is very satisfying because it has the R value of 0.924 and R² 0,854. …”
Get full text

Vaccination as a solution of the issue of resistance S. pneumoniae by H. P. Ruban, S. V. Struch

“…Composition and resistance profile of the lower respiratory tract microflora isolated from sputum pneumococcal strains in children in 2016–2018, demonstrated up to 72.4% resistance to macrolides, 31.3% resistance to cefotaxime and 8.3% – to ceftriaxone. Spn serotypes structure in under 5 years of age children with meningitis was characterized by relatively high uniformity. …”
Get full text

Neural models in diagnostics of the financial result of housing and utility enterprises by I. P. Kurochkina, I. I. Kalinin, L. A. Mamatova, E. B. Shuvalova

“…Innovations  have increased the  usability  of  the  program.  New   interface  allowed  to  analyze data  monthly.  …”
Get full text

Single-cell transcriptome analysis revealed a suppressive tumor immune microenvironment in EGFR mutant lung adenocarcinoma by Lei Yang, Qing Zhou, Bo Zhang, Yi-Long Wu, Zhi-Hong Chen, Wen-zhao Zhong, Fen Wang, Yun-Ting He, Song Dong, Xue-Wu Wei, Wei-Dong Chen, Xiao-Rong Yang, Xue-Meng Shang

“…EGFR-mutant LUAD lacked CD8+ tissue-resident memory (TRM) cells, which could promote tertiary lymphoid structure generation by secreting CXCL13. In addition, other cell types, including tumor-associated macrophages and cancer-associated fibroblasts, which are capable of recruiting, retaining, and expanding CD8+ TRM cells in the TME, were also deficient in EGFR-mutant LUAD. …”
Get full text

Gut microbiota regulates exercise-induced hormetic modulation of cognitive functionResearch in context by Elisa Cintado, Pablo Muela, Lucía Martín-Rodríguez, Ignacio Alcaide, Patricia Tezanos, Klara Vlckova, Benjamín Valderrama, Thomaz F.S. Bastiaanssen, María Rodríguez-Muñoz, María L. de Ceballos, María R. Aburto, John F. Cryan, José Luis Trejo

Get full text

CHARACTERISTICS OF PSYCHOLOGICAL MATURITY AS A SOFT-SKILL OF A MODERN PERSONALIT by Mitchenko Kateryna

“…The aim of the article is to substantiate the essence and component structure of psychological maturity, and the set of soft skills as an integral part of an individual’s psychological maturity. …”
Get full text

Prevalence of chronic HCV infection in patients with type 2 diabetes mellitus in Russia by P. A. Beliy, K. R. Dudina, O. O. Znoyko, T. N. Markova, I. A. Morozova, N. P. Blokhina, E. A. Nurmukhametova, N. D. Yushchuk

“…The proportion of patients with type 2 diabetes with markers of viral hepatitis (VH) in the Russian Federation is not known, which does not allow us to estimate the burden for the state of this medical problem.OBJECTIVE: Assessment of the prevalence of concomitant pathology, HCV infection and type 2 diabetes, as well as the proportion of severe liver damage in its structure, according to the analysis of the primary medical records of four Moscow hospitals.MATERIALS AND METHODS: A retrospective analysis of the medical records of patients with HCV infection and diabetes mellitus, who admitted at different periods to four hospitals in Moscow, was carried out, as well as a total examination for the presence of anti-HCV in the blood of all patients with diabetes who were admitted within a certain period to the endocrinology department of a multidisciplinary hospital. …”
Get full text

DUAL EDUCATION AS A MEAN OF ENSURING PROPER QUALITY OF PROFESSIONAL TRAINING OF MATHEMATICS TEACHERS IN MODERN UKRAINE by Микола Працьовитий, Оксана Требенко, Олександр Школьний, Яніна Гончаренко

“…Solving the problem is envisaged through the implementation of a set of measures to modernize the structure, content, technologies and methods of training mathematics teachers, including the development and implementation of mutually beneficial partnership models between higher education institutions, employers and students, aimed at increasing the effectiveness of practical training of future teachers for the practical application of acquired knowledge and skills, their social and professional adaptation in the conditions of real professional activity. …”
Get full text

Symptom network analysis of pregnancy stress, depressive symptoms and quality of life: a cross-sectional study of pregnant women in Xinjiang, China, 2023–2024 by Sufeila Shalayiding, Weicui Meng, Xiaoting Wang, Bahedana Sailike, Ting Jiang

“…Methods From February 2023 to January 2024, a convenience sampling method was used to conduct a cross-sectional study of 1,349 pregnant women in a tertiary hospital in the Xinjiang Uygur Autonomous Region of China using the Patient Health Questionnaire Depressive Symptom Cluster and the Stress in Pregnancy and Health-Related Quality of Life Scale, to construct a network to perform network estimation, and to determine core nodes of the network structure based on the centrality indexes. Results Maternal pregnancy stress score (1.71 ± 0.55), depressive symptoms (15.36 ± 4.70), and quality of life had the highest social functioning score (74.45 ± 12.63) and the lowest physical functioning score (65.18 ± 26.75). …”
Get full text

Study on the Impact of Exclosures on the Physicochemical Properties of Rangeland Soil (Case Study: Northern Golestan Province, Sufikam Rangelands) by Rasool Khatibi, Mohsen Farahi

“…Among the remedial methods for degraded soils, increasing rangeland fertility and striving to improve soil structure stability, reducing livestock trampling through grazing restrictions, are highlighted. …”
Get full text

Orientaciones para crear patios activos en los centros escolares (Orientations to create active playgrounds in schools) by Mª Isabel Salas Sánchez, Josep Vidal-Conti

“…The interest of this study consists primarily in specifying the main aspects that should be considered when carrying out changes in the organization and/or structure of school playground areas. The objectives which this article pursues are mainly three.  1) to show evidence from different studies of the importance of recess time in schools.  2) to establish a "road map" to carry out transformations which would help to create active and dynamic spaces contributing, above all, to the improvement of students' health and therefore allowing the teaching staff to carry out the project or program of change (given the particularities and singularities of each one of the centers) and 3) to define some transversal proposals which can be introduced within this space and time. …”
Get full text

Productivity and ecological functions of naturally regrown pine forests of the Ukrainian Polissia by Petro Lakyda, Volodymyr Blyshchyk

“…Based on the indicators of basic wood density (341 kg·(m3)-1), the studied stands have a slightly lower density compared to other pine forests of the Ukrainian Polissia zone, which are characterized by high moisture content in wood at a young age, soil conditions (structure, mechanical composition, fertility), which has a significant impact on the formation of late wood, and, consequently, on its density. …”
Get full text

A Systematic Review of the Microfinance Literature: An ADO-TCM Framework Approach by Bahman Khodapanah, Mohammad Bashokouh Ajirlou, Fariba Mesri

“…This framework provides an in-depth analysis of the structure of relevant studies, encompassing predecessors, research decisions, research outcomes (ADO), utilized theories, study contexts, and research methods (TCM). …”
Get full text

Sm2O3-induced superconductivity enhancements in bulk Y-123 ceramics synthesized via a novel modified thermal decomposition method by Ryad Alhadei Mohamed Arebat, Mohd Mustafa Awang Kechik, Yap Siew Hong, Chen Soo Kien, Lim Kean Pah, Hussien Baqiah, Fatma Barood, Syahrul Humaidi, Hoo Keong Peh, Abdul Halim Shaari, Muhammad Kashfi Shabdin, Muralidhar Miryala

Get full text

Construction and Preliminary Validation of the Children's Academic Readiness Test to Enter Primary School in Afghanistan Country by Mohammad Naeem Rasooli, Ahmad Abedi, Mohammad Ashori

“…The results also showed that the assessment test has appropriate validity (structural validity and factor analysis) and reliability (Cronbach's alpha). …”
Get full text

Lethal clinical outcome and chemotherapy and immunotherapy resistance in patients with urothelial carcinoma with MDM2 amplification or overexpression by Weijuan Zhang, Jiejie Xu, Hailong Liu, Yu Zhu, Zewei Wang, Han Zeng, Zhaopei Liu, Yuan Chang, Le Xu, Kaifeng Jin, Jingtong Xu, Xiaohe Su, Yawei Ding, Lingkai Zhang, Jiaxing Sun, Yuzhen Wu

“…In addition, UC with MDM2 amplification or overexpression was associated with an immuno-evasive contexture characterized by lower proportion of tertiary lymphoid structure infiltration, lower abundance of CD8+ T cells, IFN-γ+ cells, GZMB+ cells, and decreased expression of immune checkpoint molecules including programmed death-ligand 1 (PD-L1), programmed death-1 (PD-1) and cytotoxic T-lymphocyte-associated protein 4 (CTLA-4).Conclusions MDM2 amplification or overexpression defines a lethal subset of patients with UC with inferior prognosis and resistance to both platinum-based chemotherapy and immunotherapy irrespective of TP53/p53 status. …”
Get full text

Pulmonary and functional hallmarks after SARS-CoV-2 infection across three WHO severity level-groups: an observational study by Patrícia Blau Margosian Conti, Maria Ângela Gonçalves Oliveira Ribeiro, Carla Cristina Souza Gomez, Aline Priscila Souza, Daniela Souza Paiva Borgli, Eulália Sakano, Mauro Alexandre Pascoa, Silvana Dalge Severino, Tayná Castilho, Fernando Augusto Lima Marson, Fernando Augusto Lima Marson, Fernando Augusto Lima Marson, José Dirceu Ribeiro, UNICOVID Study Group, Adyléia Aparecida Dalbo Contrera Toro, Aline Cristina Gonçalves, Andrea de Melo Alexandre Fraga, André Moreno Morcillo, Andressa Oliveira Peixoto, Andrei Carvalho Sposito, Bianca Aparecida Siqueira, Emília Silva Gonçalves, Emília Raposo Nascimento, Gil Guerra Junior, Jenniffer Tayna Orzechowski Furtado, Lucas Rodrigues de Moraes, Maria de Fatima Corrêa Pimenta Servidoni, Mariana Zorron, Marcos Tadeu Nolasco da Silva, Maíra Seabra Assumpção, Milena Baptistela Grotta, Renan Marrichi Mauch, Simone Appenzeller, Thiago Luís Infanger Serrano

Get full text

Effects of a multicomponent exercise regimen on subchondral bone and cartilage in postmenopausal women with knee osteoarthritis: protocol for a randomized controlled trial by Ville-Markus Konola, Jari Parkkari, Juhani Multanen, Riku Nikander, Timo Rantalainen, Johanna Vesanto, Satu Pekkala, Merja Kalaja, Johanna K. Ihalainen, Benjamin Waller, Matti Munukka, Harri Sievänen, Mika Nevalainen, Hannu Kautiainen, Victor Casula, Juha Paloneva, Tommi Vasankari, Arttu Peuna, Simo Saarakkala, Miika T. Nieminen, Ari Heinonen

“…The primary outcome measures of this trial are the 8-month changes in the biochemical composition of the knee articular cartilage measured by the T1r and T2 relaxation times from quantitative magnetic resonance imaging and subchondral bone sclerosis, density and structure as measured via cone beam computed tomography. …”
Get full text

Gomphrenin-Based Decarboxylated and Acylated Pigments from Basella alba L. Fruit Extracts Impair Survival of Colorectal Cancer Cells but Not Normal Cells – In Vitro Study by Katarzyna Sutor-Świeży, Łukasz Kozioł, Mateusz Knap, Ewa Dziedzic, Monika Bieniasz, Przemysław Mielczarek, Monika Baj-Krzyworzeka, Rafał Szatanek, Sylwia Bobis-Wozowicz, Łukasz Popenda, Sławomir Wybraniec, Malgorzata Tyszka-Czochara

“…Hence, decarboxylated derivatives with potential health-promoting properties were generated by controlled thermal modifications of gomphrenin structure. Bioactivity experiments were performed on gomphrenin acylated (malabarin and globosin) and decarboxylated derivatives (17-decarboxy-gomphrenin, 2-decarboxy-gomphrenin, and 2,17-bidecarboxy-gomphrenin) derived from the fruit extracts using preparative HPLC. …”
Get full text