Dehydrotanshinone II A alleviates osteoarthritis via activating PPARγ to inhibit ferroptosis in chondrocytes by Wenli Guan, Fahu Yuan, Xin Wang

“…The study confirmed that DHT IIA could improve the articular cartilage structure of OA rats by elevating PPARγ and inhibiting ferroptosis. …”
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Current directions of cooperation between Ukraine and EU countries in the field of healthcare by Leonid Taraniuk, Renata Korsakiene, Karina Taraniuk, Kateryna Rubanenko

“…The results of this study can be useful for effective management decisions at the state and interstate levels, which are aimed at funding and grant support programs for the health sector of Ukraine.…”
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THE IMPACT OF THE USE OF BIOFUELS ON CO2 EMISSIONS AT THE LEVEL OF EUROPEAN COUNTRIES FROM THE PERSPECTIVE OF ABSOLUTE DECOUPLING by Valentina SIMION, Liviu MARCUTA, Maricel CAZACU, Nicolae MINEA, Camelia HODOAȘAN

“…Their impact is often masked by factors such as electrification policies, the adoption of renewables and the overall structure of the energy mix. To better understand the contribution of biofuels, a segmentation by economic sectors such as transport and industry is needed, which future research aims to address. …”
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Economic damage of risk factors associated with morbidity and mortality from major chronic non-communicable diseases in Russia in 2016 by A. V. Kontsevaya, D. K. Mukaneeva, A. O. Myrzamatova, Yu. A. Balanova, M. B. Khudyakov, O. M. Drapkina

“…Indirect losses due to premature mortality prevail over direct costs of medical care and disability benefits in the economic damage structure of each RF. The largest damage of four major CNCDs was associated with HTN — 869,9 billion rubles, which is equivalent to 1,01% of gross domestic product (GDP). …”
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General Cultural Competence of a Future Teacher in a Changing World by O. R. Neradovskaya, V. A. Starodubtsev

“…The results prove that the phenomenon of culture arises in the process of human coevolution. In this study, the structure and content of culture is seen as a sphere with three poles (religion, art, science). …”
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On the Issue of Practical Orientation of Teaching Students of Technical Universities the Basics of Descriptive Geometry by L. G. Polyakov, T. D. Polyakova

“…Based on the analysis of the structure of the discipline “descriptive geometry and engineering graphics", the authors propose to link the practical part of the course to a specific technical device. …”
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INDIVIDUAL STYLE OF PROFESSIONAL ACTIVITY OF FUTURE PSYCHOLOGISTS: ESSENCE AND WAYS OF FORMATION IN THE EDUCATIONAL PROCESS OF A HIGHER EDUCATION INSTITUTION by Volkova Nataliia, Bykova Viktoriia

“…The content of the individual style of future psychologists’ professional activity includes motivational-value (a system of motives, and value attitudes); cognitive (a set of knowledge about the essence and structure of the individual style of professional activity of future psychologists, ways of its formation); personal-active (methods, techniques, procedures, productive technologies, and tools of implementing psychological knowledge in work by specialities); reflective-evaluative components (an ability to professional and personal reflective). …”
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Growing CAPITOL (Critical Age Periods Impacting the Trajectory of Obesogenic Lifestyles) 4 Life by Hills AP, Burgess K, Mulcahy K, Jayasinghe S, Coghlan K, Byrne NM, Dalton LM, Ahuja KDK, Hughes R

“…Community campaigns and learning products were co-designed and activated during the balance of 2024.Discussion: The project exemplified the key principles of collective impact: establishing a shared agenda, defining success measures, coordinating aligned activities, maintaining open communication, and creating a backbone structure for support and data coordination. It offered valuable lessons for future policy and program development by emphasizing the importance of context-specific adaptation and community-led design.Keywords: asset-based community development, capacity building, childhood obesity, co-design, collective impact, community-based system dynamics, first 1000 days…”
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Loneliness and mental burden among German medical students during the fading COVID-19 pandemic: a mixed-methods approach by Marvik Leich, Jennifer Guse, Corinna Bergelt, Corinna Bergelt

“…Students' responses underscore the need for improved academic support by eased study program structure, improved counseling, and tailored services for students of different study years.…”
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Economic damage associated with excess salt intake of Russian people in 2016 by Yu. A. Balanova, A. V. Kontsevaya, A. O. Myrzamatova, D. K. Mukaneeva, M. B. Khudyakov

“…The largest contribution of excess salt intake is in the damage associated with CVD (122,8 billion rubles), where half (68,1 billion rubles) is attributable to the ED associated with stroke. In the structure of the ED of each nosology, excess salt intake cause from 4,5% (CVD in general) to 17% (for T2D) and 16,1% (stroke) of the entire damage.Conclusion. …”
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Decoding TMAO in the Gut-Organ Axis: From Biomarkers and Cell Death Mechanisms to Therapeutic Horizons by Liu J, Ge P, Luo Y, Sun Z, Luo X, Li H, Pei B, Xun L, Zhang X, Jiang Y, Wen H, Liu J, Yang Q, Ma S, Chen H

“…Furthermore, we cover recent advances in treating human diseases by regulating gut microbiota structure and enzyme activity to influence TMAO metabolism and reduce TMAO levels, including the use of probiotics, prebiotics, antibiotics, anti-inflammatory drugs, antiplatelet drugs, hypoglycemic drugs, lipid-lowering drugs, and natural products.Keywords: trimethylamine N-oxide, gut-organ axis, cell death, biomarker, therapeutic strategies…”
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Development of an Online Scenario-Based Tool to Enable Research Participation and Public Engagement in Cystic Fibrosis Newborn Screening: Mixed Methods Study by Louise Moody, Samantha Clarke, Matt Compton, Rachael Hughson-Gill, Felicity Boardman, Corinna Clark, Pru Holder, James R Bonham, Jane Chudleigh

“…As technology advances, there is the potential to expand the newborn screening program following evaluation of the likely benefits and drawbacks. …”
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Synthesis of novel 3-(2-bromophenyl)-4-substituted-1H-1,2,4-triazole-5(4H)-thiones derivatives by A. A. Safonov, A. V. Nevmyvaka

“…It was synthesized new 3-(2-bromophenyl)-4-substituted-1H-1,2,4-triazole-5(4H)-thionesand there derivatives, the structure of compounds was confirmed using Elemental analysis (CHNS), 1HNMR and Chromatographic mass spectral analysis. …”
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Response of community distribution and biodiversity of grassland plants to environmental factors based on a “3-circles” paradigm by WANG Xing, SONG Naiping, YANG Xinguo

“…The average coverage of plant showed a good restoration effect in comparison with that before enclosure and grazing prohibition, but the community structure did not change significantly, and psammophytic species were still the dominant species. …”
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Analysis of Reference Range Values of Lipid Profile and Lipid Ratio in Healthy Young Adult Population in Makassar, Indonesia by Syamsir syamsir, Liong Boy Kurniawan, Yuyun Widaningsih, Burhanuddin Bahar, Tenri Esa, Andi Ariyandy

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Land Use and is Impact on Agricultural Productivity in Mutara Sub-County Mitooma District. by Tusingwire, Pamellah

“…The findings revealed that sustainable land management practices, such as crop rotation, cover cropping, and reduced tillage, can improve soil structure, fertility, and water retention capacity as revealed by 62% who strongly agreed, 28% who agreed, 27% disagreed and 11% strongly disagreed. …”
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Inbreeding patterns and genetic diversity under selection in Teha sheep by Shunzhe Wang, Long Liang, Dilinigeer Ziyayiding, Wenjing Jiao, Hailati Kasimu, Sangang He, Mingjun Liu

“…Teha sheep, a crossbred line between Texel and Kazakh sheep, are an important meat-producing breed in China, yet their genetic structure and inbreeding status remain underexplored. …”
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Cytological Characterization of <i>vrnp 1</i>, a Pollen-Free Male Sterile Mutant in Mung Bean (<i>Vigna radiata</i>) by Yuxin Cheng, Tianjiao Lan, Kunpeng Deng, Minghai Wang, Shuying Bao, Dan Han, Yapeng Xu, Han Wang, Ning Xu, Zhongxiao Guo

“…Mung bean (<i>Vigna radiata</i>) plays a significant role in agricultural trade, food processing and utilization, and cropping structure adjustment due to its abundant nutritional components, medicine-food homology, capacity for nitrogen fixation, and soil improvement. …”
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Leveraging deep learning to discover interpretable cellular spatial biomarkers for prognostic predictions based on hepatocellular carcinoma histology by Huijuan Hu, Tianhua Tan, Yerong Liu, Wei Liang, Wei Zhang, Jinsong Zhang, Ju Cui, Jinghai Song, Xuefei Li

“…Abstract The spatial structure of various cell types in the tumour microenvironment (TME) can provide valuable insights into disease progression. …”
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Ionospheric Scintillation and Geomagnetic Disturbance Caused by Space Hurricanes by Sheng Lu, Zan‐Yang Xing, Qing‐He Zhang, Yong‐Liang Zhang, Hui‐Gen Yang, Kjellmar Oksavik, L. R. Lyons, Kazuo Shiokawa, Yong Wang, Yu‐Zhang Ma, Xiang‐Yu Wang, Tong Xu, Shu‐Ji Sun, Duan Zhang

“…Abstract A space hurricane is a large‐scale, cyclone‐shaped aurora characterized by a rotating magnetic structure and shears in plasma convection, driven by high‐latitude magnetic reconnection. …”
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