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Enhancer reprogramming: critical roles in cancer and promising therapeutic strategies
Published 2025-03-01“…This review comprehensively encapsulates the structural attributes of enhancers, delineates the mechanisms underlying their dysregulation in malignant transformation, and evaluates the therapeutic opportunities and limitations associated with targeting enhancers in cancer.…”
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7343
Development of a zoonotic influenza distribution assessment and ranking system (ZIDAR): Technical application in Nepal to support cross-sectoral risk-based surveillance
Published 2025-06-01“…This is then followed by a technical phase involving model building, model structure validation, data gathering and assessment of model performance. …”
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7344
Sustainable Mobility: Analysis of the Implementation of Electric Bus in University Transportation
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7345
Probabilistic graphical modelling of early childhood caries development.
Published 2023-01-01“…The probabilistic dependence structure on the most significant factors was modelled with an Undirected Graphical Model (UGM or Markov random fields) which provides a probabilistic reasoning approach for the establishment of multi-way associations. …”
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Operational procedure sharing pathway in veno-occlusive disease: a Delphi consensus-based recommendations
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7349
Prognostic value of the levels of CTLA-4 and its ligand B7.2 in patients with colorectal cancer
Published 2023-07-01“…The analysis of the obtained data determined the parameters that have prognostic value in the structure of the diagnostic model. Using these parameters, we developed a computer program to determine the probability of CRC in the patient.Conclusion. …”
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V.M. Bekhterev`s Pedagogical Institute for Social Breeding and Research of the Normal and Defective Child (1921-1925): Theoretical and Applied Value
Published 2018-10-01“…Petersburg, the State archive of the Russian Federation, authors reconstruct history of creation and feature of functioning of Institute, investigate its scientific educational program and possibilities of its realization in practice, characterize structure and dynamics of training of students, place emphasis on establishment of interrelation of Institute with other institutions and laboratories of Psychoneurological academy, providing his functioning infrastructure. …”
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7351
ANALYSIS OF DIRECT COSTS ASSOCIATED WITH THE USE OF WARFARIN IN PATIENTS WITH ATRIAL FIBRILLATION
Published 2016-01-01“…Aim. To analyze the structure of expenses associated with warfarin dose adjustment and international normalized ratio (INR) control for patients with atrial fibrillation (AF) per 1 year of treatment. …”
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Development of Youth Communities in the University Ecosystem: Resources, Projects, and Risks
Published 2022-09-01“…The subject of study is the structure, axiological, organizational and procedural foundations of the university ecosystem. …”
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7353
Dynamic basis of supercoiling-dependent DNA interrogation by Cas12a via R-loop intermediates
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7354
Raman Spectroscopic Characterization of Endodontic Biofilm Matrices
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7355
Estimation and evaluation of iron reserves in the eastern area of Eileh1 mine, Razavi Khorasan province
Published 2024-12-01“…This is attributed to Kriging’s ability to account for the spatial structure of the deposit, its unbiased nature, and its lower estimation variance. …”
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Discriminant analysis of occupational performance characteristics in patients with major depressive disorders and healthy individuals
Published 2024-12-01“…Abstract Aim Assessing symptoms and daily functioning in patients with major depressive disorder (MDD) can be challenging, as their limited self‐monitoring abilities may result in behavior observed during structured interviews not accurately reflecting their daily lives. …”
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The second victim phenomenon among German emergency medical technicians: a cross-sectional study based on the SeViD questionnaire (SeViD-VIII)
Published 2025-07-01“…The implementation of structured peer support programs may help mitigate the impact of SVP.…”
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Sepsis and post-sepsis syndrome: a multisystem challenge requiring comprehensive care and management—a review
Published 2025-04-01“…Timely and targeted interventions, including antimicrobial therapy, cytokine modulation, immune restoration, metabolic support, and structured rehabilitation strategies, are pivotal for improving outcomes. …”
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Estimation of the initial material of spring barley in the Rostov region
Published 2022-02-01“…There were made phenological observations, estimated varieties’ resistance to lodging and diseases, assessed productivity and conducted structural analysis of plants in points according to the estimation system of the main economically valuable traits given in the Methodological recommendations for studying the world barley and oats collection (2012). …”
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Methodology for Assessing the Transport Accessibility of Capital Objects in a Megacity Based on Geoinformation Data
Published 2022-01-01“…Purpose: to present the author's methodology and the test results for calculating integral indicators of transport accessibility on the basis of weighted normalized private indicators for three housing estates in Moscow.Methods: the study is based on the application of methods for collecting factual material, its processing, systematic, comparative historical and structural-functional analysis, which were supplemented by multivariate analysis of secondary information using content analysis of existing methods for calculating indicators of transport accessibility of capital objects. …”
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