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Rapid Genotyping of <i>FecB</i> Mutation in Sheep Using CRISPR-Cas12a Integrated with DNA Nanotree Biosensing Platform
Published 2025-02-01“…A similar DNA origami technique-based fluorescence reporter nanotree structure was synthesized using gold nanomagnetic beads as carriers to amplify the fluorescence signal further. …”
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Coaching unified sports: associations between perceived athlete improvement, barriers, and coach attitudes across five European countries
Published 2025-08-01“…Although institutional, social, and logistical barriers to Unified Sports were widely recognized by participants, these factors did not independently predict attitudes once other variables were controlled for.ConclusionThe findings underscore the motivational role of observed progress among athletes with disabilities in shaping coach engagement and suggest that experiential factors such as previous involvement and personal ties may carry unanticipated emotional or structural challenges. These insights point to the importance of designing coach education and support programs that not only promote technical competence but also address emotional resilience and contextual demands. …”
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Implementation and Costs of an Agroforestry System in a Degraded Area of the Brazilian Semi-Arid Region
Published 2025-04-01“…Specifically, we analyzed the system’s establishment process, estimated its costs, assessed structural development over time, and compared species performance and carbon accumulation across different biodiversity arrangements. …”
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Predicting HIV self-testing intentions among Chinese college students: a dual-model analysis integrating health belief constructs and machine learning prioritization
Published 2025-07-01“…Random forest modeling prioritized these psychological constructs (mean decrease Gini >2.5), identifying male students and arts majors as critical subpopulations requiring targeted intervention.DiscussionOur dual-method analysis establishes that campus HIV control necessitates: 1) Gender-specific prevention programs addressing male students’ elevated risk exposure; 2) HBM-informed education strengthening self-efficacy and environmental cues; 3) Structural interventions reducing testing barriers through discreet service delivery. …”
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Mixed Ni-Co sub-stoichiometric spinels as catalytic precursors for dry reforming of methane
Published 2025-09-01“…On the other hand, all the reduced catalysts presented a comparable structure, with crystallites of sizes between 20 and 30 nm composed of a homogeneous Ni-Co alloy, with the absence of isolated metals. …”
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Cryptic species and hybridisation in corals: challenges and opportunities for conservation and restoration
Published 2024-11-01“…Here, we investigate the prevalence of cryptic coral groups and assess evidence for their permeability to gene flow (hybridisation) via a structured literature review of genomic studies. Using reproducible criteria to detect distinct genetic groups that are sympatric, we find that 68% of nominal species represented in population genomic studies show evidence for comprising partially reproductively isolated groups and that these distinct groups are often linked by gene flow. …”
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A roadmap for personalized medicine: the findings of the IC2PerMed project
Published 2025-07-01“…The roadmap promotes best practice exchange and addresses potential barriers to PM adoption. It outlines structural actions including enhancing health literacy, fostering intersectoral and international collaboration, ongoing review of emerging technologies, and facilitating innovation market entry through needs assessment and Health Technology Assessment. …”
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Cross-species single-cell transcriptomic atlas of retinal photoreceptors reveals molecular signatures underlying color vision adaptation
Published 2025-09-01“…Summary: The retina exhibits conserved structural and functional features across species, yet the evolutionary mechanisms underlying color vision remain unclear. …”
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Time Course of Morphological Changes in Red Blood Cells and Banked Whole Blood Biochemical Parameters in Different Storage Periods
Published 2013-02-01“…Objective: to reveal the patterns of blood biochemical changes, a trend in poikylocytosis, and impairment in the ultra-structure of red blood cells of the whole blood stored in citrate-phosphate-dextrose-adenine-1 during long-term storage. …”
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Improving the efficiency of the medicine provision system for patients with malignant neoplasms
Published 2022-07-01“…We analyzed the regulatory legal documents regulating drug care and drug provision in the Russian Federation, data from depersonalized (anonymized) registers of the structure of hospitalizations in a day hospital for 2021. …”
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The status of machine learning in HIV testing in South Africa: a qualitative inquiry with stakeholders in Gauteng province
Published 2025-08-01“…A follow-up study should assess the feasibility, structural challenges, and design implementation strategies for the integration of machine learning in HIV testing in South Africa.…”
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Electromagnetic textile absorber applied to 4G and 5G bands
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Mechanisms of immune regulation and transplantation immunity in corneal transplants
Published 2020-01-01“…Unlike other kinds of transplants, corneal grafting is often performed without tissue typing and systemic immunosuppression.High frequency of transparent corneal engraftment (up to 90% of cases) in the absence of risk factors is due to special immunoprivileged area in the anterior eye segment (functionally, a structural aggregation of the cornea and anterior chamber, AC) accomplished by local and systemic immunoregulatory mechanisms, i.e., phenomenon of immune deviation associated with anterior chamber of the eye (ACAID), components of the internal liquid medium, a watery moisture with immunosuppressive properties, e.g., IL-1ra, TSP-1,TGF-β2, regulatory complement proteins, α-MSH (alpha-melanocyte stimulating hormone), VIP (vasoactive intestinal peptide), indolamine 2,3-dioxygenase (IDO), calcitonin-gene-bound peptide (CGRP), somatostatin, etc.In addition to ACAID and liquid AC components, a contribution to the maintenance of immune privilege which is extremely important for a successful outcome of keratoplasty, is provided by other mechanisms, in particular, immunologically active membrane-associated molecules of corneal endothelium, i.e., PDL-1 (Programmed death ligand 1), and sVEGFR-1, sVEGFR-2, sVEGFR-3 involved in maintaining avascularity of the corneal tissue. …”
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The effect of rTMS intervention with different targets on neural remodeling in stroke patients: a randomized controlled trial
Published 2025-07-01“…Functional connectivity analysis revealed significantly increased resting-state functional connectivity (rsFC) in the contralateral dentate nucleus and ventromedial premotor area of the affected side in the SMA group relative to the M1 group (p = 0.0319), with this enhancement showing a strong positive correlation with balance function improvement (r = 0.637, p = 0.001). Structural MRI analysis indicated that while the M1 group exhibited a significant increase in gray matter volume (GMV) in the medial segment of the postcentral gyrus (p = 0.02), the SMA group showed significant GMV increases in the posterior cerebellum and chorionic lobule (p = 0.0428) that demonstrated a moderate positive correlation with improved balance function (r = 0.436, p = 0.038). …”
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Uncovering the factors of financial well-being: the role of self-control, self-efficacy, and financial hardship
Published 2025-04-01“…To test the hypotheses concerning the direct and indirect relationships between self-regulation factors and financial well-being, partial least squares structural equation modeling (PLS-SEM) was employed. …”
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AIGC Using Behavior Analysis from the Perspective of Artificial Intelligence Literacy
Published 2024-11-01“…[Method/Process] This study adopts a mixed-method approach that primarily integrates Structural Equation Modeling (SEM) and mediation analysis to explore the relationships between the factors that influence AIGC tool usage. …”
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