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5261
Assessment of Spatial Proportions of the Tax Potential of Small and Medium Enterprises in a Resource Type Region
Published 2024-11-01“…Purpose of the study – to determine the spatial structure and concentration of tax revenues from the activities of small and medium enterprises (SMEs) in municipal entities of the resource-type region (based on materials from the Kemerovo Region – Kuzbass), to characterize their compliance with the needs of local budgets.Materials and methods. …”
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5262
Highly selective HPK1 inhibitor NDI-101150 mediates immune cell activation and robust antitumor responses, distinct from immune checkpoint blockade
Published 2025-07-01“…Genetic HPK1 kinase inactivation or knockout in mice leads to immune cell activation and tumor growth suppression, providing a strong rationale for targeting HPK1 kinase activity as an immuno-oncology therapy.Methods A structure-guided drug design approach was used to identify a highly potent and selective small molecule inhibitor of HPK1 kinase activity, NDI-101150. …”
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5263
Epidemiological Aspects of Monitoring the Sensitivity of <i>Staphylococcus aureus</i> Strains
Published 2025-04-01“…Conclusion. In the general structure of microorganisms of the hospital, Staphylococcus aureus strains prevailed (50%). …”
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5264
Epigenetic Modifiers to Treat Retinal Degenerative Diseases
Published 2025-06-01“…To extend our findings, we tested the hypothesis that this effect was due to altered chromatin structure by using a range of inhibitors of chromatin condensation to prevent photoreceptor degeneration in the rd10 mouse model. …”
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5265
Dysphagia in pediatric intensive care unit patients (review)
Published 2023-12-01“…The review analyzes the causes, features of diagnosis and treatment of dysphagia in pediatric patients with PIСS. 5 groups of causes in the structure of PIСS that can lead to the development of dysphagia were considered: infectious-trophic, vegetative-metabolic, neuromuscular, emotional-cognitivecomplications and decreased quality of life compared to the premorbid level. …”
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5266
First rangewide density estimate of the endemic and isolated Luangwa giraffe in Zambia
Published 2025-05-01“…However, sparse monitoring since the early 1900s has limited inferences about population size, structure, and range. To address this, we conducted the most spatially extensive and systematic survey to date of Luangwa giraffe across its distribution, extending survey effort 120 km south of their officially recognized extent. …”
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5267
Informational and analytical support of planning processes of marketing actions in high-speed trains
Published 2018-02-01“…The functionality created on the basis of ACS “Express” is a flexible system of reports that are formed at the user's request, allowing you to view information on the structure of passenger traffic with varying degrees of detail for compiling programs to stimulate demand and analyze its effectiveness.…”
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5268
Clinical and epidemiological characteristic of chronic hepatitis C in the republic of Tyva
Published 2023-04-01“…The clinical profile of typical patients with chronic hepatitis C was established; whose share in the total structure of the examined was 38.4%. Conclusion: There is a tendency to reduce the incidence of chronic hepatitis C in the Republic of Tyva. …”
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5269
EPIDEMIOLOGICAL ASPECTS THE INCIDENCE OF CANCER OF THE KIDNEY AND BLADDER IN PRIMORSKY KRAI
Published 2017-03-01“…The incidence of bladder cancer in men tended to rise from the continental bioclimatic zone to the coast in all ecological zones mainly due to differences in the structure of the bioclimate between the coast and continental areas of Primorsky Krai. …”
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5270
MITOCHONDRIAL DYSFUNCTION AS POSSIBLE CAUSE OF IMPAIRED FOLLICULAR DEVELOPMENT
Published 2016-06-01“…Mitochondria play leading role in senescence program realization. One of the early manifestations of this process is loss of reproductive function in female (menopause). …”
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5271
Impact of multidimensional assessment on anti-fracture treatment decisions in patients with fragility hip fractures within a Fracture Liaison Service
Published 2025-05-01“…Conclusion The integration of the MPI into multidisciplinary taking care of old patients with hip fractures may provide a structured approach for individualizing treatment decisions, considering aspects such as prognosis, functional autonomy, and cognitive status. …”
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5272
Deuterium retention in tungsten oxide: the role of oxide damage
Published 2025-01-01“…The findings provide insight into the behavior of tungsten oxides under deuterium implantation, emphasizing the importance of considering its thermal stability and its structural modifications at the surface of tungsten plasma facing components.…”
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5273
Predicting leakage of the VERCORS mock-up and concrete containment buildings - a digital twin approach
Published 2022-03-01“…An important numerical effort has also been made to implement structural computations of the mock-up and to capitalize these computations as well as their post-processing (so as to compare automatically with the monitoring data) in what can be called a digital twin of the mock-up. …”
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5274
Interpersonal and systemic factors in initiating, developing and maintaining collaborations between European neurosurgical departments and institutions in low-resources settings: A...
Published 2025-01-01“…Material and methods: We conducted a prospective qualitative study using semi-structured interviews with fourteen matched neurosurgeons—seven from European centers and seven from LMIC institutions—engaged in such collaborations. …”
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5275
Modificaciones a un transportador apilador de sacos de azúcar // Modifications to a decker transporter of sugar sacks.
Published 2000-07-01“…<br />In the developed work it is achieved that with the same capacity and transportation longitude, as well as with the same<br />technical solution to vary the angle of inclination in the wanted range, diminish the total weight of the equipment in 20%,<br />with the employment of a professional program, the structural solution is changed and the thickness of the profiles is<br />decreased, eliminate the problems of stability. …”
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5276
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5277
Conceptualizing the Public Component of Green Finance
Published 2025-03-01“…The generalization of scientific viewpoints from domestic and foreign economic science regarding the essence and structure of green finance has enabled the distinction of both public and private components within it. …”
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5278
Development of intelligent monitoring system for tension overhead line construction based on multi-parameter sensing
Published 2025-07-01“…., and then it builds up the overall structure of the system’s monitoring points. Aiming at the characteristics of field construction of tension wire, a real-time data collection and processing model is designed, and LoRa communication technology and 4G communication technology are selected to interconnect the self constructed local area network and 4G wide area network, so as to complete the on-site interaction and long distance transmission of data. …”
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5279
Demographic and socioeconomic factors affecting relative poverty level of older adults in Türkiye
Published 2025-07-01“…Policies addressing older adults should incorporate flexible solutions based on household structure, prioritize health issues, and enhance community support. …”
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5280
Radiation-hygienic monitoring and assessment of the doses of the public residing on the radioactively contaminated territories of the Tula region
Published 2019-09-01“…Additionally, it included the assessment of the dynamics of concentration of 137Cs and 90Sr in food products, maximal values of mean annual effective doses of the public and contribution of the collective dose from medical exposure into the structure of the annual collective dose of the public. …”
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