Mechanisms of immune regulation and transplantation immunity in corneal transplants by V. V. Neroev, N. V. Balatskaya, E. V. Chentsova, Kh. M. Shamkhalova

“…Unlike other kinds of transplants, corneal grafting is often performed without tissue typing and systemic immunosuppression.High frequency of transparent corneal engraftment (up to 90% of cases) in the absence of risk factors is due to special immunoprivileged area in the anterior eye segment (functionally, a structural aggregation of the cornea and anterior chamber, AC) accomplished by local and systemic immunoregulatory mechanisms, i.e., phenomenon of immune deviation associated with anterior chamber of the eye (ACAID), components of the internal liquid medium, a watery moisture with immunosuppressive properties, e.g., IL-1ra, TSP-1,TGF-β2, regulatory complement proteins, α-MSH (alpha-melanocyte stimulating hormone), VIP (vasoactive intestinal peptide), indolamine 2,3-dioxygenase (IDO), calcitonin-gene-bound peptide (CGRP), somatostatin, etc.In addition to ACAID and liquid AC components, a contribution to the maintenance of immune privilege which is extremely important for a successful outcome of keratoplasty, is provided by other mechanisms, in particular, immunologically active membrane-associated molecules of corneal endothelium, i.e., PDL-1 (Programmed death ligand 1), and sVEGFR-1, sVEGFR-2, sVEGFR-3 involved in maintaining avascularity of the corneal tissue. …”
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The effect of rTMS intervention with different targets on neural remodeling in stroke patients: a randomized controlled trial by Li Zhao, Li Chen, Qiu Wang, Xinyi Li, Sha Li, Chunxiao Wan

“…Functional connectivity analysis revealed significantly increased resting-state functional connectivity (rsFC) in the contralateral dentate nucleus and ventromedial premotor area of the affected side in the SMA group relative to the M1 group (p = 0.0319), with this enhancement showing a strong positive correlation with balance function improvement (r = 0.637, p = 0.001). Structural MRI analysis indicated that while the M1 group exhibited a significant increase in gray matter volume (GMV) in the medial segment of the postcentral gyrus (p = 0.02), the SMA group showed significant GMV increases in the posterior cerebellum and chorionic lobule (p = 0.0428) that demonstrated a moderate positive correlation with improved balance function (r = 0.436, p = 0.038). …”
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Maternal and gestational factors associated with congenital anomalies among live births: a nationwide population-based study in Brazil from 2012 to 2020 by Qeren Hapuk Rodrigues Ferreira Fernandes, Enny S. Paixão, Maria da Conceição Nascimento Costa, Maria Glória Teixeira, Mauricio Lima Barreto, Angelina Xavier Acosta

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EDUCATIONAL TOURISM AS A BASIS FOR THE GROWTH OF ECONOMIC ACTIVITY OF THE LABOR MARKET by Olesia Iastremska

“…Theoretical and practical analysis of the work of specialists in the field of educational tourism and the functioning of the labor market has proved the need to use such research methods: monographic, analysis and synthesis, structural-logical method, systematic approach, theoretical generalization. …”
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Improving the efficiency of the medicine provision system for patients with malignant neoplasms by Yu. A. Agafonova, D. V. Fedyaev, A. V. Snegovoy, V. V. Omelyanovskiy

“…We analyzed the regulatory legal documents regulating drug care and drug provision in the Russian Federation, data from depersonalized (anonymized) registers of the structure of hospitalizations in a day hospital for 2021. …”
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Sustainable building: Achieving thermal comfort in hot and humid climate using building performance simulation by Niniek Pratiwi, Abdi Gunawan Djafar, Rahmayanti Rahmayanti, Nur Mutmainnah, Arlan Kaharu

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An Image Grid Can Be Worth a Video: Zero-Shot Video Question Answering Using a VLM by Wonkyun Kim, Changin Choi, Wonseok Lee, Wonjong Rhee

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THE INFLUENCE OF THE LEVEL OF SOCIAL INTELLIGENCE DEVELOPMENT ON THE CHOICE OF RESPONSE STRATEGY IN CONFLICT SITUATIONS by Olena V. Karapetrova

“…The concept of social intelligence, its structure and functions, modern approaches to the problem of social intelligence development in young people are considered. …”
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“Standard Assessment Framework”: A Proposal to Fill a Gap in the “Paris Declaration” by Hellmut W. Eggers, Daniel Svoboda

“…It therefore presents simultaneously, however, a general grid that should structure findings in a much more detailed way, to be consigned to a SAF Data-Base that can be built up on the basis of experiences made in the past and on those accumulating further under current evaluation work. …”
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Socio-Demographic Factors Contributing to Teenage Pregnancy in Bidibidi Refugee Settlement Zone Four Yumbe District. by Momone, Evaline

“…The socio-demographic factors contributing to teenage pregnancy include age, socioeconomic status, education, family structure, cultural and religious influences, access to healthcare, peer influence, geographical location, and media impact. …”
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Cryptic species and hybridisation in corals: challenges and opportunities for conservation and restoration by Riginos, Cynthia, Popovic, Iva, Meziere, Zoe, Garcia, Vhon, Byrne, Ilha, Howitt, Samantha M., Ishida, Hisatake, Bairos-Novak, Kevin, Humanes, Adriana, Scharfenstein, Hugo, Richards, Thomas, Briggs, Ethan, Clark, Vanessa, Lei, Chuan, Khan, Mariam, Prata, Katharine E.

“…Here, we investigate the prevalence of cryptic coral groups and assess evidence for their permeability to gene flow (hybridisation) via a structured literature review of genomic studies. Using reproducible criteria to detect distinct genetic groups that are sympatric, we find that 68% of nominal species represented in population genomic studies show evidence for comprising partially reproductively isolated groups and that these distinct groups are often linked by gene flow. …”
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Comprehensive approach to the choice of therapy in patients with osteoarthritis at the first visit to the doctor. Expert consensus (literature review and resolution) by A. M. Lila, O. N. Tkacheva, N. N. Yakhno, A. V. Naumov, L. I. Alekseeva, Yu. V. Kotovskaya, M. V. Putilina, M. L. Kukushkin, A. Yu. Kochish, E. A. Taskina, G. R. Abuzarova

“…Pain relief is a priority in the formation of individual therapeutic programs for patients with OA, starting from their first request for medical assistance. …”
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Protocol to develop a 3D mouse autologous lung tumor-immune spheroid co-culture model to advance radiotherapy-based treatments by Sergio León, Sofía Torres Quintas, Nerea Otegui, Miriam Redrado, José Javier Aristu, María José Oliveira, Alfonso Calvo, Flávia Castro, Diego Serrano

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Species and index diversity of macrofungi from two different locations in East Kalimantan by MUHAMMAD FAUZI ARIF, HILDIANA APRILIANI DHIU DEMO, FERDINA YULIANI, NUBLI HAZMI, IMAM ROSADI, ERVINDA YULIATIN, SUGIANUR SUGIANUR, HERY ABRIYANTO

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Spontaneous and activation-induced apoptosis of peripheral blood mononuclear cells in the pathogenesis of type 1 diabetes mellitus by A. V. Lugovaya, N. M. Kalinina, V. Ph. Mitreikin, Yu. V. Emanuel, Yu. P. Kovalchuk, A. V. Artyomova

“…The key point in the T1DM initiation is apoptosis resistance of activated autoreactive T lymphocytes, that migrate from bloodstream to the pancreas and take an active part in destruction of the pancreatic insular structures. Despite long studies of T1DM pathogenesis, the exact causes of resistance of effector T cell clones to apoptosis remain unclear. …”
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Facing your fears in schools: using the ADIS/ASA to characterize anxiety and intervention outcomes in students with autism or suspected autism by Judy Reaven, Judy Reaven, Kelly T. Cosgrove, Kelly T. Cosgrove, Ainsley Losh, Ainsley Losh, Sarah Nickles, Sarah Nickles, Connor M. Kerns, Katherine Pickard, Audrey Blakeley-Smith, Audrey Blakeley-Smith, Lisa Hayutin, Lisa Hayutin, Allison T. Meyer, Allison T. Meyer, Caitlin Middleton, Caitlin Middleton, Nuri M. Reyes, Nuri M. Reyes, Richard E. Boles, Richard E. Boles

“…The Anxiety and Related Disorders Interview Schedule for DSM-5 with Autism Spectrum Addendum is a semi-structured interview that captures both DSM-5 and distinct presentations of anxiety. …”
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Apoptotic extracellular vesicles derived from human dental pulp stem cells facilitate periodontal tissue regeneration by Junyi Xia, Zeyu Zhang, Jinlong Weng, Guanxiong Zhu, Zidan Xu, Liting Zeng, Janak Lal Pathak, Lina Yu

“…Abstract Objective Apoptotic extracellular vesicles (ApoEVs) derived from human dental pulp stem cells (hDPSCs) are subcellular structures released during programmed cell death. These vesicles carry rich biological information and regulatory potential, and have demonstrated significance in regulating cell behavior and tissue repair. …”
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Evaluation Method of Pyroclastic Rock Reservoir Based on Gravel Parent Rock Composition by DONG Lei, LI Wentao, DING Yonghao, ZHANG Zhiguo, XIA Xue, PANG Jiarui, GAO Feng

“…As a result, the calculation accuracy of reservoir porosity parameters is low, the pore structure is complex, and fluid identification is difficult. …”
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Plant diversity and transcriptional variability assessed by retrotransposon-based molecular markers by R. N. Kalendar, K. S. Aizharkyn, O. N. Khapilina, A. A. Amenov, D. S. Tagimanova

“…Retrotransposon activity can occur during development, cell differentiation and stress, and a source of chromatin instability and genomic rearrangements. Both the overall structure of retrotransposons and the domains responsible for the various phases of their replication are highly conserved in all eukaryotes. …”
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Dilated Blood and Lymphatic Microvessels, Angiogenesis, Increased Macrophages, and Adipocyte Hypertrophy in Lipedema Thigh Skin and Fat Tissue by Sara AL-Ghadban, Walter Cromer, Marisol Allen, Christopher Ussery, Michael Badowski, David Harris, Karen L. Herbst

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