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6181
Deep learning and genomic best linear unbiased prediction integration: An approach to identify potential nonlinear genetic relationships between traits
Published 2025-06-01“…Deep learning (DL) offers a promising alternative for capturing nonlinear genetic relationships due to its ability to identify complex patterns without prior assumptions about the data structure. We proposed a novel hybrid model that that combines both DL and GBLUP (DLGBLUP), which uses the output of the traditional GBLUP, and enhances its predicted genetic values (PGV) by accounting for nonlinear genetic relationships between traits using DL. …”
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6182
The mediating role of entrepreneurial attitude with entrepreneurial education and self-efficacy on students' entrepreneurial mindset
Published 2025-02-01“…., 2005), entrepreneurial attitude (Chen & Linan, 2009), and understanding of entrepreneurial mindset (Arnolf & Matthiessen, 2013). Structural equation modeling using the partial least squares method and SmartPLS3 software was employed to test the hypotheses. …”
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Synthesis, physical-chemical and biological properties of 1,8-disubstituted compounds of theobromine. III. 8-Amino-p-chlorobenzyltheobromines
Published 2014-08-01“…There have been developed available laboratory-based methods for the synthesis of 8-aminosubstituted 1-p-chlorobenzyltheobromine, the structure of which has been proved by data obtained from elemental analysis and NMR- spectroscopy. …”
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Adherence to Medical Treatment in Elderly Patients with Coronary Artery Disease in the Settings of Primary Outpatient Care
Published 2021-05-01“…Medical history and structure of pharmacotherapy do not influence level of adherence in this population. …”
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6187
Territorially Stratified Modeling for Sustainable Management of Free-Roaming Cat Populations in Spain: A National Approach to Urban and Rural Environmental Planning
Published 2025-08-01“…These data were stratified by municipal population size and applied to national census figures to generate a model-ready demographic structure. We then implemented a stochastic simulation using Vortex software to project long-term population dynamics over a 25-year horizon. …”
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6188
Modeling the Meaning of Individual Words Using Cultural Cartography and Keystroke Dynamics
Published 2024-12-01“…The material of the study is a newly developed dataset containing associative reactions to the keywords of Russian culture, anonymized data about the informants, as well as the reaction time while producing associations measured using a program that records keystrokes. The proposed research methodology includes both the existing approaches (automatic extraction of relations from texts based on data from language models and methods of vector semantics, i.e., “cultural cartography using word embeddings”) and a new list of features developed by the authors to describe individual differences in the meaning of a word based on the data from neurobiology about the meaning structure of word. …”
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6189
A Proposed Diagnostic and Treatment Algorithm for the Management of Lumbar Discogenic Pain
Published 2025-07-01“…., Walnut Creek, CA, USA; 12Private Practice, San Francisco, CA, USACorrespondence: Jon E Block, Private Practice, 2210 Jackson Street, Ste. 401, San Francisco, CA, 94115, USA, Tel +1 415-775-7947, Email jb@drjonblock.comBackground: There is renewed interest in the intervertebral disc as a target for treatments aimed at ameliorating lumbar discogenic pain by restoring and preserving the natural structure and function of this component of the vertebral motion segment.Methods: Using a modified Delphi methodology involving a panel of 11 experts, we developed a simple, understandable clinical algorithm to serve as a foundation for objective decision making regarding the diagnosis and treatment of lumbar discogenic pain throughout the entire continuum of care. …”
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6190
Precise aftershock activity in the marine source region of the 2024 Noto-Hanto earthquake by rapid response observation using ocean bottom seismometers
Published 2025-04-01“…A velocity model was derived from the velocity structure by the marine seismic survey. Focal mechanisms were estimated using the grid search method based on the polarities of the first Pwave arrivals. …”
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High-Dose Ceftriaxone in Elderly Patients with Enterococcal Infective Endocarditis: Population Pharmacokinetics of Free Ceftriaxone and Dose Optimization
Published 2025-05-01“…Ceftriaxone free concentration was measured at three time-points: before the administration (C<sub>min</sub>) and two and four hours after ceftriaxone administration (C<sub>2</sub> and C<sub>4</sub>). Both structural and covariate population pharmacokinetic models were built. …”
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Constitutive inflammation and epithelial-mesenchymal transition dictate sensitivity to nivolumab in CONFIRM: a placebo-controlled, randomised phase III trial
Published 2025-07-01“…Non-synonymous and neoantigen mutation burden were no different between groups, however R-mesotheliomas were infiltrated with activated CD8+ T- and CD19+ B-lymphocytes, organised into tertiary lymphoid structures. B-cell infiltration correlated with pro-inflammatory chemokines including IL24 and CCL19. …”
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Perspectives of Caregivers on Access to Health Care for Children with CKD
Published 2024-11-01“…Methods: Caregivers of Australian children aged 0 to 16 years, across all CKD stages, from low socioeconomic status backgrounds, and/or residing in rural or remote areas, purposively sampled from 5 centers, participated in semi structured interviews on accessing health care. Transcripts were analyzed thematically. …”
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Measuring Faculty Excellence: Introducing a Model
Published 2025-03-01“…There are various criteria for this evaluation, which generally focus more on research performance, while the main objective of hiring faculty members has been the development of education. The common structure of academic scoring, rewarding research More than teaching (4). …”
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Fifty years of geophysical researches of glaciers in Institute of Geography, the Russian Academy of Sciences, 1966–2016
Published 2016-12-01“…Basic results of these studies are the following: (1) the new data on the ice thicknesses, ice volumes, subglacial relief, internal structure, and thermal state of the glaciers were obtained; (2) the two‑layered (polythermal) glaciers consisting of the upper layer of cold ice and the lower layer of temperate water‑filled ice had been revealed in Svalbard for the first time; spatial distribution of cold, polythermal and temperate glaciers had been determined; (3) the evidences were obtained that measured changes in thickness of the upper cold ice layer in polythermal glaciers can be used to estimate the long‑period variations of regional climates and serve as regional paleothermometers; (4) methods for estimating the water content in temperate and polythermal glaciers from the RES data were developed; and its space‑time variations in temperate ices of the Svaldbald glaciers were estimated since even small water content inside of them can noticeably change their dynamic behavior; (5) methods for estimating the ice volume within glaciers in large regions of mountain and polar glaciations had been created; the ice storages were estimated in Svalbard, Franz Josef Land, Dzhungrsky Alatau, the Great Caucasus, and Mt. …”
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