Nuclear receptor-SINE B1 network modulates expanded pluripotency in blastoids and blastocysts by Ka Wai Wong, Yingying Zeng, Edison Tay, Jia Hao Jackie Teo, Nadia Omega Cipta, Kiyofumi Hamashima, Yao Yi, Haijun Liu, Tushar Warrier, Minh T. N. Le, Soon Chye Ng, Qi-Jing Li, Hu Li, Yuin-Han Loh

“…Abstract Embryonic stem cells possess the remarkable ability to self-organize into blastocyst-like structures upon induction. These stem cell-based embryo models serve as invaluable platforms for studying embryogenesis and therapeutic developments. …”
Get full text

Enhancing antioxidant activity of corn bract and silk juices through biotransformation of polyphenols by Lactobacillus paracasei TJ199 fermentation by Xiaohui Tang, Huanyong Lv, Hailong Wang, Huixin Yang, Baogang Zhang, Ling Cong, Xinyi Li, Menghan Ma, Yunhe Xu, Lili Zhang

Get full text

PREVENTION OF DENTAL CARIES IN THE CONDITIONS OF ECOLOGICAL POLLUTION by I.V. Kovach, H.V. Shtompel, Ye.N. Dychko, A.V. Verbytska

“…However, the use of treatment and prophylactic complex improved the bone structures density. The level of calcium and phosphate in the oral fluid of the observed individuals had recovered to optimal after three years of use of treatment and prophylactic complex, contributed to effective secondary mineralization both in temporary and in permanent teeth. …”
Get full text

Assessment of health-related quality of life and adherence to antituberculosis therapy among patients in three tertiary hospitals in Sierra Leone: a cross-sectional study by Michael Lahai, Sally-Mattu Conteh, Ahmed Vandy, Onome T. Abiri, Brian Thompson, Mohamed Bawoh, Alvin Turay, Peter Bai James

“…Method An institutional-based cross-sectional study was conducted using a structured questionnaire to collect data from 384 patients from Connaught Hospital, Lakka and Kenema government hospitals. …”
Get full text

Feeding practices during childhood illness and associated factors among mothers of children under 24 month olds in southwest Ethiopia: A Facility-based cross-sectional study design by Diribsa Tizazu Hailu, Vinod Bagilkar, Ebissa Bayana, Tesfaye Asfaw, Merga Garoma Jatu, Assefa Desalew, Mulualem Keneni, Fentahun Meseret, Tigist Demeke

“…Methods A facility-based cross-sectional study was conducted from May 20 to June 20, 2023, involving 415 participants selected through a systematic random sampling technique.Data were collected through face-to-face interviews using a pretested, structured questionnaire.Data entry and analysis were performed using Epidata version 4.6 and Statistical Package for Social Science version 25.0, respectively. …”
Get full text

Incorporation of vasa previa screening into a routine anomaly scan: A single center cohort study by Millicent Nwandison, Elizabeth Daly‐Jones, Alexandra Drought, Lisa Story, Philippe De‐Rosnay, Neil Sebire, David Nyberg, Yinka Oyelese

“…We suggest the inclusion of structured VP assessment in standard fetal anomaly screening programs.…”
Get full text

Knowledge attitudes and practices of healthcare workers on respirator fit testing and PAPR use at a university medical center by Fatimah Alshahrani, Abba Elgujja, Lulwa Alabdan, Jaser S. Alharbi, Ali A. Rabaan, Ibrahim Alzayid, Mohammed Alasiri, Khalid Faqihi, Samih Alanazi

“…A total of 204 HCWs from different departments and hospitals around the medical center participated in cross-sectional research. Structured surveys measuring demographic variables, knowledge, attitudes, training experience, and compliance with fit testing and PAPR use gathered data. …”
Get full text

Prevalence and predictors of malocclusion among students in special needs schools in Amhara region, Ethiopia by Amare Teshome Tefera, Biruk Girma Bekele, Zelalem Aniley, Aynishet Adane, Tadesse Awoke Ayele, Kefyalew Ayalew Getahun, Simegnew Handebo, Semira Ali, Abebe Muche

“…Data were collected from 396 students attending special needs schools in the region using a pre-designed, structured, interviewer-administered questionnaire. …”
Get full text

The Consolidated Approach to Intervention Adaptation (CLARION): Developing and undertaking an empirically and theoretically driven intervention adaptation by Lydia Ould Brahim, Sylvie D. Lambert, Nancy Feeley, Jane McCusker, Dan Bilsker, Mark J. Yaffe, Rosetta Antonacci, Stephanie Robins, John William Kayser, Christine Genest, Haida Paraskevopoulos, Jessica Blair, Andrea Laizner

“…These were added to form CLARION, which was structured in two stages: the first involves selecting an intervention, identifying core components, and deciding on modifications; the second stage solicits interest stakeholder feedback to assess the acceptability of the preliminary adapted intervention (pre-test). …”
Get full text

Delivering the Lee Silverman voice treatment-loud method in-site versus telerehabilitation in people with multiple sclerosis: Feasibility evidence of a non-inferiority pilot random... by Chiara Vitali, Giulia Fusari, Diego Michael Cacciatore, Giulia Smecca, Cinzia Baldanzi, Alessio Carullo, Marco Rovaris, Davide Cattaneo, Francesca Baglio, Sara Isernia

“…The present study provides the feasibility evidence on patient-relevant structural and procedure effects of a pilot randomized controlled trial comparing LSVT-Loud telerehabilitation (Tele-LSVT-Loud) versus standard delivery. …”
Get full text

Immune predictors of response to immune checkpoint inhibitors in mismatch repair-deficient endometrial cancer by Etienne Rouleau, Ana Oaknin, Christophe Klein, Alexandra Leary, Sebastien Gouy, Patricia Pautier, Catherine Genestie, Amandine Maulard, Judith Michels, Marco de Bruyn, Emeline Colomba-Blameble, Annechien Plat, Juan Francisco Grau Bejar, Elisa Yaniz Galende, Qinghe Zeng, Audrey Le Formal, Elodie Edmond, Maëva Moreau

“…However not all responses and predictors of primary resistance are lacking.Methods We compared the immune tumor microenvironment of MMRd EC ICI-responders (Rs) and ICI non-responders (NRs), using spatial multiplexed immune profiling and unsupervised hierarchical clustering analysis.Results Overall, NRs exhibited drastically lower CD8+, absent terminally differentiated T cells, lack of mature tertiary lymphoid structures and dendritic cells, as well as loss of human leukocyte antigen class I. …”
Get full text

A Deep Learning-Based Probabilistic Approach for Non-Destructive Testing of Aircraft Components Using Laser Ultrasonic Data by Adriano Liso, Cosimo Patruno, Angelo Cardellicchio, Pierfrancesco Ardino, Nicola Gallo, Giuseppe del Prete, Valerio Dentico, Veronica Vespini, Sara Coppola, Pietro Ferraro, Vito Reno

“…Composite structures are commonly used in complex applications such as automotive and aerospace due to their high strength-to-weight ratio. …”
Get full text

Endophytic fungi as a source of antimicrobial compounds against emerging methicillin-resistant Staphylococcus aureus by Shefali Bansal, Mahavir Joshi, Prachi Mahajan, Smile Sharma, Sukhminderjit Kaur, Babita Thakur, Prabhjot Singh Jassal, Ranjan Singh, Manikant Tripathi

Get full text

PPARγ promotes urothelial remodeling during urinary tract obstruction by Mohammad El-Harakeh, Felipe Rodriguez-Tirado, Andrew J. Hardman, Alexa Miehls, Oumoulkhairy Camara, Kelly M. Grounds, Glenis Tocaj, Macie Kercsmar, Birong Li, Xin Wang, Brian Becknell, Ashley R. Jackson

“…Prior studies show that congenital and acquired UTO initiate a conserved, protective program of renal urothelium remodeling that culminates in expansion of uroplakin (UPK)+ cells to promote renal structural integrity. …”
Get full text

Impact of Early-Life Brain Injury on Gut Microbiota Composition in Rodents: Systematic Review with Implications for Neurodevelopment by Vanessa da Silva Souza, Raul Manhães-de-Castro, Sabrina da Conceição Pereira, Beatriz Souza de Silveira, Caio Matheus Santos da Silva Calado, Henrique José Cavalcanti Bezerra Gouveia, Jacques-Olivier Coq, Ana Elisa Toscano

Get full text

Factors associated with the serum 25-hydroxyvitamin D levels in adults by Sue-Hsien Chen, Shu-Ching Chen, Yo-Ping Lai, Pin-Hsuan Chen, Kun-Yun Yeh

“…Sociodemographic data were obtained through structured questionnaires, while anthropometric measurements, hemogram results, and biochemical markers were collected from medical records and physical examination findings. …”
Get full text

Understanding patients’ perceptions of uncomplicated low back pain: a theory-informed qualitative study using the Common-Sense Self-Regulation Model by Shannon M. Ruzycki, Yamile Jasaui, Sameh Mortazhejri, Shawn Dowling, D’Arcy Duquette, Stefanie Linklater, Kelly Mrklas, Gloria Wilkinson, Jeremy M. Grimshaw, Andrea M. Patey, on behalf of the De-Implementing Wisely Research Group

Get full text

Effect of pilates on the physical and mental health of drug-dependent individuals — a randomized controlled trial by Feng Ji, Ensong Zhou, Peng Zhao, Xinliang Chen, Hui Wang, Jiabin Zhong, Yi Zhang, Yunhang Lu, Qing Zhang

“…Specifically, the study seeks to evaluate changes in body composition, physical fitness, blood biochemistry, and psychological outcomes following a structured Pilates intervention. Methods This study was conducted as a double-blind, parallel-group, randomized controlled trial. …”
Get full text

Prevalence and determinants of Musculoskeletal Disorders among quarry workers in The Gambia: a cross-sectional study by Ebrima Touray, Lamin Sambou, Balla Jammeh, Sambou L S Kinteh, Bakary Kinteh, Amadou Barrow

Get full text

Impact of Nutritional Education Intervention on Mothers Knowledge, Practices and Nutritional Status of Children Under-Five in Rural Mangaluru, Karnataka: A Quasi-experimental Pilot... by Savitha Naik, Abhay Nirgude, Priya Reshma Arahna

“…Data were collected using a structured knowledge questionnaire and an observational practice checklist. …”
Get full text