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Mechanisms of immune regulation and transplantation immunity in corneal transplants
Published 2020-01-01“…Unlike other kinds of transplants, corneal grafting is often performed without tissue typing and systemic immunosuppression.High frequency of transparent corneal engraftment (up to 90% of cases) in the absence of risk factors is due to special immunoprivileged area in the anterior eye segment (functionally, a structural aggregation of the cornea and anterior chamber, AC) accomplished by local and systemic immunoregulatory mechanisms, i.e., phenomenon of immune deviation associated with anterior chamber of the eye (ACAID), components of the internal liquid medium, a watery moisture with immunosuppressive properties, e.g., IL-1ra, TSP-1,TGF-β2, regulatory complement proteins, α-MSH (alpha-melanocyte stimulating hormone), VIP (vasoactive intestinal peptide), indolamine 2,3-dioxygenase (IDO), calcitonin-gene-bound peptide (CGRP), somatostatin, etc.In addition to ACAID and liquid AC components, a contribution to the maintenance of immune privilege which is extremely important for a successful outcome of keratoplasty, is provided by other mechanisms, in particular, immunologically active membrane-associated molecules of corneal endothelium, i.e., PDL-1 (Programmed death ligand 1), and sVEGFR-1, sVEGFR-2, sVEGFR-3 involved in maintaining avascularity of the corneal tissue. …”
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The effect of rTMS intervention with different targets on neural remodeling in stroke patients: a randomized controlled trial
Published 2025-07-01“…Functional connectivity analysis revealed significantly increased resting-state functional connectivity (rsFC) in the contralateral dentate nucleus and ventromedial premotor area of the affected side in the SMA group relative to the M1 group (p = 0.0319), with this enhancement showing a strong positive correlation with balance function improvement (r = 0.637, p = 0.001). Structural MRI analysis indicated that while the M1 group exhibited a significant increase in gray matter volume (GMV) in the medial segment of the postcentral gyrus (p = 0.02), the SMA group showed significant GMV increases in the posterior cerebellum and chorionic lobule (p = 0.0428) that demonstrated a moderate positive correlation with improved balance function (r = 0.436, p = 0.038). …”
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The contribution of personalized video feedback to robotic partial nephrectomy training in realistic 3D tumor kidney models: design, production and implementation
Published 2025-07-01“…This suggests that structured preparatory training with objective performance targets can enhance learning outcomes in surgical simulation. …”
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Species and index diversity of macrofungi from two different locations in East Kalimantan
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Cuidar de pessoas transexuais na ótica dos residentes de enfermagem [Care for transgender people from the nursing resident’s perspective] [Cuidar de personas transexuales en la ópt...
Published 2018-09-01“…Method: an exploratory, qualitative, descriptive study was conducted in 2017, in the urology unit of a university hospital Rio de Janeiro city, by semi-structured interview of 13 first- and second-year nursing residents of the clinical surgery program. …”
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Factors associated with uptake and acceptability of cervical cancer screening among female sex workers in Northeastern Uganda: A cross-sectional study.
Published 2025-01-01“…Data was collected using structured investigator administered questionnaire and analyzed using Stata statistical software version 15.0 (Stata Corp, Texas, USA). …”
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Knowledge, Attitude and Practice on Needle Stick Injury Management among Nurses and Nursing Students: A Cross-sectional Study
Published 2025-07-01“…Data were collected using a structured, self-administered questionnaire divided into four sections: demographic details and KAP. …”
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FACTORS ASSOCIATED WITH ANXIETY AND DEPRESSION SPECTRUM DISORDERS IN BEHCHET’S DISEASE
Published 2018-07-01“…ADSDs were diagnosed by a psychiatrist according to the ICD-10 during semi-structured interviews using the Hospital Anxiety and Depression Scale (HADS), the Hamilton Anxiety Rating Scale (HAM-A), and the Montgomery-Asberg Depression Rating Scale (MADRS). …”
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Identidad profesional diada docente-discente: Implicancias en el proceso de enseñanza-aprendizaje de matronería
Published 2025-07-01“…Method: The research was qualitative interpretative by means of semi-structured interviews with 17 teachers and 16 students of the university degree of Obstetrics and Childcare of the Universidad de Antofagasta, Chile. …”
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Cryptic species and hybridisation in corals: challenges and opportunities for conservation and restoration
Published 2024-11-01“…Here, we investigate the prevalence of cryptic coral groups and assess evidence for their permeability to gene flow (hybridisation) via a structured literature review of genomic studies. Using reproducible criteria to detect distinct genetic groups that are sympatric, we find that 68% of nominal species represented in population genomic studies show evidence for comprising partially reproductively isolated groups and that these distinct groups are often linked by gene flow. …”
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Evaluation Method of Pyroclastic Rock Reservoir Based on Gravel Parent Rock Composition
Published 2024-04-01“…As a result, the calculation accuracy of reservoir porosity parameters is low, the pore structure is complex, and fluid identification is difficult. …”
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Plant diversity and transcriptional variability assessed by retrotransposon-based molecular markers
Published 2017-03-01“…Retrotransposon activity can occur during development, cell differentiation and stress, and a source of chromatin instability and genomic rearrangements. Both the overall structure of retrotransposons and the domains responsible for the various phases of their replication are highly conserved in all eukaryotes. …”
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Infections in patients with acute luekemia treated with different regimens
Published 2025-05-01“…Aim of the study: to analyze the frequency and structure of infectious complications in patients with acute leukemia, who received different chemotherapy regimens. …”
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Gold-coated ZnO nanostructures on no-core optical fiber for ammonia detection in food spoilage applications
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A systematic scoping review of mentor training in medical education between 2000 and 2024
Published 2025-07-01“…Five key domains were identified: 1) mentor qualities, 2) training structure, 3) content, 4) outcomes, and 5) obstacles. …”
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