In silico and in vivo Study of the Anti-Inflammatory Activity of Azomethine Derivatives of 2-amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide and 2-substituted 5,6,7,8-tetra... by Chiriapkin, A.S., Kodonidi, I.P., Abisalova, I.L., Diakova, I.N.

“…In silico prediction of anti-inflammatory activity was performed using the AutoDock 4.0 program. The virtual structures of the test compounds were constructed in HyperChem 8.0.4. …”
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Efficacy of neoadjuvant chemotherapy with docetaxel and cisplatin in patients with squamous cell carcinoma of the oral cavity at high risk of progression by S. I. Kutukova, Yu. V. Ivaskova, N. P. Beliak, G. A. Raskin, A. A. Varankina, A. I. Yaremenko, A. Ya. Razumova, A. O. Cheremnykh, M. F. Manna, R. V. Orlova

“…At the 1st stage of our study, we retrospectively analyzed the data of 98 patients and determine that the NACT for patients with oral cavity squamous cell carcinoma, with 3 or more factors of an unfavorable prognosis (peripheral blood parameters indicating the presence of systemic inflammation, reduced level of infiltration of tumor structures by CD8‑tumor infiltrating lymphocytes and low expression of programmed death-ligand 1 (PD-L1) on tumor and immune cells) significantly reduces the risk of death and disease progression: hazard ratio 0.33; 95 % confidence interval 0.13–0.86; p = 0.0231. …”
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Factors Associated with Caregiver Burden in Families of Patients with Palliative and Chronic Illness: A Cross-Sectional Study by Haroen H, Juniarti N, Sari CWM, Prista Sari S, Arovah NI, Pardosi JF, Wibowo DA

“…At the same time, feelings of not being optimal enough in providing care were the statement most frequently acknowledged by caregivers.Conclusion: Psychosocial and structural factors influence caregiver burden. These findings highlight the need for integrated interventions, including psychosocial support, financial security, and caregiver education, to mitigate burden in this population.Keywords: caregiver burden, chronic illness, family caregiver, palliative care…”
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Substantiation of the necessity to develop a competency model of training specialist in pharmacy on the basis of intellectual educational system by V. O. Demchenko, O. A. Ryzhov, N. A. Ivankova

“…The study was conducted using the methods of semantic evaluation of legal and scientific documents, comparison, systemic and structural logical analysis. Results and discussion. …”
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Characterization of Biocalcium Microparticles from Saltwater Crocodile (<i>Crocodylus porosus</i>) Bone and Their Potential for Enhancing Fish Bologna Quality by Theeraphol Senphan, Natthapong Mungmueang, Supatra Karnjanapratum, Sutee Wangtueai, Akkasit Jongjareonrak, Suthasinee Yarnpakdee

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A Systematic Review of Maternal and Child Health Policies in Addressing Stunting: Trends and Challenges by Pratiwi Ramlan, Phill Sukri, Muh. Tang Abdullah, Muhammad Akmal Ibrahim, Jamaluddin Ahmad, Khaeriyad Adri

“…Data analysis from various studies emphasized the importance of evidence-based strategies that combine medical interventions with structural, social and economic transformation. Conclusion: In conclusion, this review emphasizes the importance of collaboration between various sectors, including health, education, and agriculture, in addressing stunting. …”
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Development of a Holistic Nursing Model Based on Transcultural Nursing to Improve the Quality of Life of Patients with Type-2 Diabetes Mellitus by Ni Wayan Suniyadewi, Yuni Sufyanti Arief, Ninuk Dian Kurniawati, I Dewa Ayu Rismayanti, Ni Wayan Trisnadewi, Iswatun Iswatun

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Machine Learning-Based Prediction of First Trimester Down Syndrome Risk in East Asian Populations by Chen YT, Chen GJ, Lin YS

“…Yen-Tin Chen,1,2 Gina Jinna Chen,3 Yu-Shiang Lin1 1In-Service Master Program in Artificial Intelligence in Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; 2Department of Obstetrics and Gynecology, Taipei Chang Gung Memorial Hospital, Taipei, Taiwan; 3Department of Electronic and Electrical Engineering, Southern University of Science and Technology, Shenzhen, People’s Republic of ChinaCorrespondence: Yu-Shiang Lin, In-Service Master Program in Artificial Intelligence in Medicine, College of Medicine, Taipei Medical University, No. 250, Wuxing St., Xinyi Dist., Taipei City, 110, Taiwan, Email eriklin@tmu.edu.twPurpose: Down syndrome is the most common chromosomal abnormality in newborns, often leading to developmental delays and congenital structural anomalies. …”
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Combined analysis of 16S rRNA gene sequencing data reveals core vaginal bacteria across livestock species by Lucille C. Jonas, Lucille C. Jonas, Curtis R. Youngs, Stephan Schmitz-Esser, Stephan Schmitz-Esser

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Impact measuring the of technological innovation driven by co-creation of value on the performance of multinationals in emerging markets by Geraldo Cardoso de Oliveira Neto, Oseias do Prado Soares, Benny Kremer Costa, Rodrigo Neri Bueno da Silva, Priscila Rezende da Costa, Roberto Bernardes, Flávio Luiz Rodrigues, André Silva de Carvalho, Dirceu da Silva

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Entrustable Professional Activities (EPAs) for Medical Student Leadership Curriculum Across Campuses by Joann Farrell Quinn, Kira K Zwygart, Amy B Smith, Deborah DeWaay, Michael Dowdy, Robin Schroeder

“…SELECT’s dual-campus structure, spanning Tampa, FL, and Allentown, PA, presents a unique opportunity to implement and assess EPAs in a longitudinal fashion across four years of training on both campuses; the Tampa campus and regional campus in Allentown.   …”
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LVRT Measurement Model and Transient Parameter Identification of Wind Turbine Based on Chaotic Particle Swarm by Dan LI, Shiyao QIN, Shaolin LI, Jing HE

“…Firstly, based on the DFIG model and control structure of the Power System Integrated Stability Program (PSASP), a low voltage ride through (LVRT) control mathematical model is established to analyze the fault transient process, and the LVRT transient control core parameters are clarified. …”
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Enhancing antioxidant activity of corn bract and silk juices through biotransformation of polyphenols by Lactobacillus paracasei TJ199 fermentation by Xiaohui Tang, Huanyong Lv, Hailong Wang, Huixin Yang, Baogang Zhang, Ling Cong, Xinyi Li, Menghan Ma, Yunhe Xu, Lili Zhang

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Building the 8-star doctor: a modified Delphi study to define, teach, and assess health professions education for undergraduate medical students by Sara Jamil Khan, Rahila Yasmeen, Shazia Imran

“…Abstract Background As global trends in medical education shift toward integrated curricula, there remains a lack of consensus on the core components of Health Professions Education (HPE) to be embedded within undergraduate medical programs. This study aims to identify and structure key HPE topics relevant to the MBBS curriculum, with the goal of enhancing students’ foundational competencies in teaching, leadership, and professionalism. …”
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An In Silico Investigation of the Pathogenic G151R G Protein-Gated Inwardly Rectifying K⁺ Channel 4 Variant to Identify Small Molecule Modulators by Eleni Pitsillou, Julia J. Liang, Noa Kino, Jessica L. Lockwood, Andrew Hung, Assam El-Osta, Asmaa S. AbuMaziad, Tom C. Karagiannis

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In Vivo Cell Migration and Growth Within Electrospun Porous Nanofibrous Scaffolds with Different Pore Sizes in a Mouse Pouch Model by David C. Markel, Therese Bou-Akl, Bin Wu, Pawla Pawlitz, Xiaowei Yu, Liang Chen, Tong Shi, Weiping Ren

“…Cellular infiltration into traditional electrospun nanofibers (NFs) is limited due to their dense structures. We were able to obtain polycaprolactone (PCL) NFs with variable and defined pore sizes and thicknesses by using a customized programmed NF collector that controls the moving speed during electrospinning. …”
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Stress among police officials in Kerala, India: an analysis of organizational and operational factors by Mini GK, Chitra Venkateswaran, Anjana VM, Sangeeth Krishna S, Greeshma J, Greeshma PS, Revathy K, Vilma Irazola, John Romate

“…The present study examines the specific stressors associated with the operational demands and organizational structures experienced by police officers in the state of Kerala, India. …”
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Whole-brain gray matter volume and fractional anisotropy of the posterior thalamic radiation and sagittal stratum in healthy adults correlate with the local environment by Keisuke Kokubun, Kiyotaka Nemoto, Toshiharu Ikaga, Yoshinori Yamakawa

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Automated high-throughput quantification of mitotic spindle positioning from DIC movies of Caenorhabditis embryos. by David Cluet, Pierre-Nicolas Stébé, Soizic Riche, Martin Spichty, Marie Delattre

“…The mitotic spindle is a microtubule-based structure that elongates to accurately segregate chromosomes during anaphase. …”
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Finding the Root of the Pathos in the Planning System of Iran: 5-why Technique by Elham Vafaei, Gholamreza Geraeinejad

“…To answer this important question, the pathology of the planning system is examined from two dimensions: Its stages (preparation and compiling (prerequisite, structure, process and product), approval, pre-implementation, implementation and Supervision and evaluation) and its source (inside and outside the organization). …”
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