Medium-Chain Acyl-CoA Deficiency: Outlines from Newborn Screening, In Silico Predictions, and Molecular Studies by Serena Catarzi, Anna Caciotti, Janita Thusberg, Rodolfo Tonin, Sabrina Malvagia, Giancarlo la Marca, Elisabetta Pasquini, Catia Cavicchi, Lorenzo Ferri, Maria A. Donati, Federico Baronio, Renzo Guerrini, Sean D. Mooney, Amelia Morrone

“…Bioinformatics predictions based on both phylogenetic conservation and functional/structural software were used to characterize the new identified variants. …”
Get full text

Modeling Aberrant Angiogenesis in Arteriovenous Malformations Using Endothelial Cells and Organoids for Pharmacological Treatment by Eun Jung Oh, Hyun Mi Kim, Suin Kwak, Ho Yun Chung

Get full text

Antimicrobial resistance in a protracted war setting: a review of the literature from Palestine by Ramya Kumar, Osama Tanous, David Mills, Bram Wispelwey, Yara Asi, Weeam Hammoudeh, Omar Dewachi

“…Notably, most studies attributed AMR to local practices, often overlooking broader structural and socio-political drivers. This review underscores the need to contextualize AMR within the environment, particularly under conditions of sustained warfare.IMPORTANCEThis study goes beyond merely reviewing and summarizing data on AMR in the occupied Palestinian territories (oPt), a region enduring chronic war-like conditions. …”
Get full text

Why do older adults hesitate to get the flu vaccine? A cross-sectional study on vaccine hesitancy in the post-COVID-19 era by Xinyue Wang, Sanmei Wen, Jiaqian Wu, Ziyi Cui, Hong Shen, Shiyao Hu, Shujun Zeng, Yan Tang

“…Multinomial logistic regression models were used to identify predictors of vaccine hesitancy, adjusting for sociodemographic variables, self-reported health status and self-report vaccination experiences. Structural equation modeling (SEM) was employed to examine the underlying factors contributing to vaccine hesitancy and quantify their interrelationships.ResultsA high proportion (85.2%) of participants exhibited influenza vaccine hesitancy, with 16.2% being complete refusers. …”
Get full text

Distribution of variants of the <i>TNFA</i> gene regulatory sites among Russian women of Caucasian origin with leiomyoma by V. I. Konenkov, A. V. Shevchenko, V. F. Prokofiev, E. G. Koroleva

“…The aim of our research was to analyze the distribution of TNF-238, TNF- 308 and TNF-863 structural variants at the regulatory region of the TNFA gene in a representative group of Caucasian patients with UF compared with a matched group of healthy women followed by assessment of personalized prognostic significance of suggested differences. 180 patients diagnosed with uterine fibroids and 98 practically healthy women were examined. …”
Get full text

Detection of single nucleotide polymorphisms associated with litter size in goats using genotyping-by-sequencing and association analysis by Satoshi Kubota, Thara Wongdee, Pramote Paengkoum

“…After filtering for allele depth and missing genotype data, the retained SNPs were subjected to population structure analysis and association analysis with the nine traits. …”
Get full text

Female Anopheles Mosquito Gut Microbiota: Description and Impact on Transmission of Plasmodium Parasite by Salisu, H. L., Yayo, A. M., Sharif, A. A., Dambatta, A. S.

“…Key focus areas include the structure and diversity of Anopheles gut microbiota, their immunomodulatory functions, interactions with P. falciparum, and potential applications in paratransgenesis and biological vector control.  …”
Get full text

DYNAMICS OF DISABILITY ADJUSTED LIFE YEARS (DALY) AS A RESULT OF PREMATURE MORTALITY OF CHILDREN AT THE AGE OF 0–17 YEARS IN TOMSK REGION IN 2008–2012 by О. S. Kobyakova, I. A. Deev, N. Ya. Nesvetailo, V. А. Boykov, I. P. Shibalkov, E. S. Kulikov, M. N. Milkevitch, E. А. Starovoitova

“…The number and gender and age structure of the population of the Tomsk Region according to Rosstat data were also considered. …”
Get full text

Parvirus infection markers in persons with exantemic diseases and in risk groups by I. N. Lavrentieva, A. Yu. Antipova, M. A. Bichurina, I. V. Khamitova, O. N. Nikishov, A. A. Kuzin

“…Typical is the winterspring seasonality; in terms of the age structure – prevalence of children 3–6 (25,3% of cases) and 7–14 (33,3% of cases) years old was detected. …”
Get full text

TrBot: A Turkish Deep Learning Chatbot Utilizing Seq2Seq Model by Bilal Babayigit, Habibelahi Rahmani, Mohammed Abubaker

“…This architecture allows TrBot to manage sequential dependencies and effectively generate coherent responses, offering advantages in handling the complex morphological structure of Turkish. In contrast to earlier Turkish chatbots that were application-specific, TrBot is designed for broad conversational use across various topics. …”
Get full text

Clinical fnd epidemiological features of measles by adults in modern period by V. V. Basina, E. V. Esaulenko, K. E. Novak, M. A. Bichurina, L. V. Lyalina

“…Positive results have been achieved during the implementation of the measles elimination program in the Russian Federation and in the Northwestern Federal District (NWFD). …”
Get full text

The impact of lifestyle sports on the sleep quality of depressed high school students in Jiangsu Province, China: based on cross-sectional study by Xianghe Chen, Yuxin Yang, Jianbo Hu, Shengjie Jin, Pengcheng Lu, Xinyu Zeng, Xiaoyan Yi, Rongbin Yin, Chenghao Zhong

“…The mediation model of depression between lifestyle sports and sleep quality was constructed via the Model4 model and other models in the SPSS macro program Process4.0. From the 32,974 valid questionnaires, 14,943 depressed high school students (SDS ≥ 53) were screened out, and structural equation modeling of the relationships between the six dimensions of lifestyle sports and the sleep quality of depressed high school students has been established via AMOS 28.0. …”
Get full text

A rural practice affinity model: recognizing the role of emergency medicine competency by Eliseo Orrantia, Theresa Kline, Lindsay Nutbrown, Erin Cameron, Margaret Cousins

“…A partial correlation matrix between the variables of interest (general self-efficacy, emergency medicine competency, rural practice self-efficacy, and rural practice intentions) - controlling for the effects of relationships, financial aspects, personal aspects, and social desirability - was created and subjected to a structural equation model. Results: Our initial rural practice affinity model resulted in a poor fit of the model to the data. …”
Get full text

Strengthening health system's capacity for pre-exposure prophylaxis for adolescent girls and young women and adolescent boys and young men in South Africa (SHeS'Cap-PrEP): Protocol... by Edward Nicol, Trisha Ramraj, Mbuzeleni Hlongwa, Wisdom Basera, Ngcwalisa Jama, Carl Lombard, Tracy McClinton-Appollis, Darshini Govindasamy, Desiree Pass, Noluntu Funani, Sarah Aheron, Ariana Paredes-Vincent, Jennifer Drummond, Mireille Cheyip, Sibongile Dladla, Jason Bedford, Cathy Mathews

“…In South Africa, various approaches of delivering PrEP have been adopted at different service delivery points (facility-based only, school-based only, community-based only and hybrid school-facility and community-facility models) to overcome challenges associated with individual, structural, and health systems related barriers that may hinder access to and uptake of PrEP among these populations. …”
Get full text

Spatial variation in time to diagnosis of visceral leishmaniasis in Bihar, India by Emily S. Nightingale, Joy Bindroo, Pushkar Dubey, Khushbu Priyamvada, Aritra Das, Caryn Bern, Sridhar Srikantiah, Ashok Kumar, Mary M. Cameron, Tim C. D. Lucas, Sadhana Sharma, Graham F. Medley, Oliver J. Brady

Get full text

Research on Multi-objective Shielding Intelligent Optimization Method Based on Non-dominated Sorting Genetic Algorithm NSGA-Ⅲ by WANG Mengqi, ZHENG Zheng, MEI Qiliang, PENG Chao, GAO Jing, ZHOU Yan

“…The model played a key role in optimizing the shielding structure above the hatch cover, paying particular attention to the dimensions of the concrete and polyethylene layers. …”

Investigation of the influence of engine displacement along the aircraft wing on the propagation of a condensation trail by A. I. Zhelannikov, A. N. Zamyatin

“…It is also significant that a contrail, interacting with a wake vortex, can reveal its structure and visualize the wake vortex propagation and decay processes. …”
Get full text

Morbidity Patterns and Determinants of Healthcare-Seeking Behavior Among Older Women in Selected Rural Areas of Bangladesh by Shahinur Akter, Tazrin Azad, Md. Habibur Rahman, Md. Firoz Raihan

“…Conclusion On the basis of the findings, we suggest that the traditional extended family structure should be sustained, wherein older people are treated with care and respect, thereby promoting healthy aging in rural Bangladesh. …”
Get full text

Turkish validity and reliability study of the simulation self-report cognitive load measurement tool 2.0 by Hilal Yıldız Çelik, Esra Uğur

“…Results The tool measures a three-factor structure—intrinsic load, extraneous load, and germane load—and consists of 16 items. …”
Get full text

Psychological characteristics of children with bronchial asthma depending on the level of control and therapeutic strategy by S. M. Nedelska, O. D. Kuznietsova

“…Children differed significantly in mother (χ2 = 37.7; P < 0.01) and self-association (χ2 = 111.7; P < 0.01) by the structure of chosen color. The first group patients chose red, green and blue colors, children with BA were characterized by passive behavior without activity and initiative in need of heightened protection and attention. …”
Get full text