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Pre-clinical safety studies of intranasal virus-like particles based vaccine for prevention of COVID-19
Published 2025-03-01“…In the subchronic toxicity study on rats, no changes in the general condition, behavior, or death of animals were noted. The structure of internal organs, blood and urine tests, hemostasis did not differ significantly between the groups. …”
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Particularities in differential diagnostics of epileptogenic brain malformations on the low-field MRI-device
Published 2019-04-01“…In 24 patients were revealed structural brain changes that have neuroradiological signs of brain malformations. …”
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SELECTION CRITERIA OF COMPOUNDS FOR DEVELOPMENT OF HIGH-POTENT ANALGESICS AND OTHER CNS DRUGS
Published 2019-01-01“…In order to analyze best practices, develop a strategy for highly effective controlled medicinal and veterinary drugs (analgesics, anesthetics, antidotes and other vital therapies) and coordinate theirdevelopment and production it is necessary to create competent management structure combining the tasks of provision of civilian population and personnel of national defense agencies of effective and safe drugs.…”
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Design and beam dynamics studies of low energy beam transport for MEHIPA
Published 2025-01-01“…This accelerator will have an Electron Cyclotron Resonance Ion Source (ECR-IS) producing 30 keV proton beam, which will be transported, matched, and focused into the first accelerating structure—the Radio Frequency Quadrupole (RFQ)—through a Low Energy Beam Transport (LEBT) channel. …”
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Metabolism of tryptophan in non-small lung cancer patients with different effect of PD-1 / PD-L1 inhibitors immunotherapy
Published 2022-06-01“…Introduction. In the structure of cancer incidence, lung cancer ranks first among men. …”
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Automatic identification of Parkinsonism using clinical multi-contrast brain MRI: a large self-supervised vision foundation model strategyResearch in context
Published 2025-06-01“…Occlusion sensitivity mapping in the correctly-classified cases (n = 160 PD and n = 114 PPS) highlighted the brain regions guiding discrimination mainly in sensorimotor and midline structures including cerebellum, brain stem, ventricle and basal ganglia. …”
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Genetic diversity and phylogenetic relationship through the use of microsatellites in Gossypium hirsutum L.
Published 2025-03-01“…Clustering based on molecular data classified the germplasm into three groups and measuring genetic distance through Euclidean distance while structure analysis revealed three gene-exchanging populations, representing a limited genetic basis in breeding programs. …”
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EPR study of interlayer interaction in Gd<sub>2</sub>O<sub>3</sub>/Fe nanostructure
Published 2021-06-01“… In this work, a nanoscale structure consisting of contacting layers of a metal of the iron subgroup and a rare earth metal oxide (REM) is considered. …”
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Synthesis and transformation in the series of 2-((5-(2,4- and 3,4-dimethoxyphenyl)-3H-1,2,4-triazole-3-yl)thio)acetic acids
Published 2021-03-01“…Physical and chemical properties were investigated for the synthesized compounds. The structure of the obtained substances was confirmed by elemental analysis, IR-spectroscopy, 1H NMR-spectrometry, and their individuality were established by thin-layer chromatography. …”
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Ultrasound patterns of metastases from papillary thyroid cancer in soft tissues of the neck
Published 2022-09-01“…The first pattern, including the depth-to-width ratio in the transverse scanning plane and the echo structure, has a sensitivity (Se) of 97 %, diagnostic accuracy (Ac) of 96.5 %, area under the curve (AUC) of 96 %, the probability ranges from 95 to 99 %. …”
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Emergence and evolution of rare ST592 blaNDM-1-positive carbapenem-resistant hypervirulent Klebsiella pneumoniae in China
Published 2025-03-01“…Conjugation-related elements were predicted using oriTfinder. The plasmid structure was visualized using Circos, and a possible evolutionary model was constructed using BioRender.ResultsIsolates KPZM6 and KPZM16 were identified as ST592 and KL57, respectively, and were collected from the same department. …”
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THEORETICAL AND PRACTICAL VIEW OF FINANCIAL REGULATION OF INNOVATIVE ACTIVITIES IN THE CONDITIONS OF WAR IN UKRAINE
Published 2025-07-01“…Based on this, a model of financial regulation for innovative activity is proposed, featuring a clearly defined hierarchical structure that includes the following key components: goal and objective setting, strategy development, selection of financial stimulation tools, and monitoring of their effectiveness. …”
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Exploring Human-centered AI Literacy Education: Interpretation and Insights from UNESCO's AI Competency Framework for Teachers and Students
Published 2024-08-01“…It analyzes the content of both the AI CFS and the AI CFT, focusing on key principles and framework structure to systematically interpret the framework's content. …”
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Practical Aspects of the Implementation of Screening for the Detection of Malignant Neoplasms of the Cervix during the Medical Examination
Published 2023-09-01“…The study of the population structure of circulating human papillоmavirus (HPV) types, and evaluation of the effectiveness of the recommended diagnostic models will improve the direction of the fight against cervical cancer and introduce optimal preventive solutions.Aim. …”
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Development of a Method for Obtaining Nanoscale Magnesium Carbonate Stabilized with Chitosan as the Basis of Scaffold Matrices for Regenerative Medicine
Published 2024-12-01“…The creation of three-dimensional matrices based on scaffolds for the formation of systems that are as close as possible to bone tissue in structure has been studied. It is known that the active substances of the scaffold matrix can be hydroxyapatite, tricalcium phosphate, as well as silicates, carbonates of magnesium, calcium, copper, zinc, and manganese. …”
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Prognostic role of demographic indicators and Charlson comorbidity index in oxygen-dependent patients with coronavirus disease (COVID-19)
Published 2023-01-01“…We used the WHO age classification when analyzing the age structure of patients. The Charlson comorbidity index was calculated for each patient. …”
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