ATF7IP inhibits Sorafenib-induced ferroptosis in hepatocellular carcinoma cells by inhibiting CYB5R2 transcription and stabilizing PARK7 protein by Yijie Su, Sirui Huang, Yang Duan, Liang Zhang, Shengyun Feng, Yingge Lv, Bei Lan, Chenghao Xuan

“…Ferroptosis, an iron-dependent form of programmed cell death, arises from the accumulation of lipid peroxides at toxic levels. …”
Get full text

Sm2O3-induced superconductivity enhancements in bulk Y-123 ceramics synthesized via a novel modified thermal decomposition method by Ryad Alhadei Mohamed Arebat, Mohd Mustafa Awang Kechik, Yap Siew Hong, Chen Soo Kien, Lim Kean Pah, Hussien Baqiah, Fatma Barood, Syahrul Humaidi, Hoo Keong Peh, Abdul Halim Shaari, Muhammad Kashfi Shabdin, Muralidhar Miryala

Get full text

CHARACTERISTICS OF PSYCHOLOGICAL MATURITY AS A SOFT-SKILL OF A MODERN PERSONALIT by Mitchenko Kateryna

“…The aim of the article is to substantiate the essence and component structure of psychological maturity, and the set of soft skills as an integral part of an individual’s psychological maturity. …”
Get full text

A Systematic Review of the Microfinance Literature: An ADO-TCM Framework Approach by Bahman Khodapanah, Mohammad Bashokouh Ajirlou, Fariba Mesri

“…This framework provides an in-depth analysis of the structure of relevant studies, encompassing predecessors, research decisions, research outcomes (ADO), utilized theories, study contexts, and research methods (TCM). …”
Get full text

Vaccine Hesitancy and Immunization Patterns in Central and Eastern Europe: Sociocultural, Economic, Political, and Digital Influences Across Seven Countries by Kurpas D, Stefanicka–Wojtas D, Soll–Morka A, Lomper K, Uchmanowicz B, Blahova B, Bredelytė A, Dumitra GG, Hudáčková V, Javorska K, Juhász Z, Manulik S, Mohos A, Skarbalius E, Tkachenko VI, Uchmanowicz I

“…Differences were influenced by healthcare system structure, public trust, exposure to misinformation, and digital communication strategies.Conclusion: Addressing vaccine hesitancy requires targeted, context-sensitive communication and digital literacy programs. …”
Get full text

Effects of a multicomponent exercise regimen on subchondral bone and cartilage in postmenopausal women with knee osteoarthritis: protocol for a randomized controlled trial by Ville-Markus Konola, Jari Parkkari, Juhani Multanen, Riku Nikander, Timo Rantalainen, Johanna Vesanto, Satu Pekkala, Merja Kalaja, Johanna K. Ihalainen, Benjamin Waller, Matti Munukka, Harri Sievänen, Mika Nevalainen, Hannu Kautiainen, Victor Casula, Juha Paloneva, Tommi Vasankari, Arttu Peuna, Simo Saarakkala, Miika T. Nieminen, Ari Heinonen

“…The primary outcome measures of this trial are the 8-month changes in the biochemical composition of the knee articular cartilage measured by the T1r and T2 relaxation times from quantitative magnetic resonance imaging and subchondral bone sclerosis, density and structure as measured via cone beam computed tomography. …”
Get full text

Cloning and identification of human colipase-like 3 and its homologous cDNAs by LU Yan, XUE Yong-chang, YU Peng, WANG Ping-zhang

“…CL PSL3 was widely expressed and highly conserved in mammalian animals, such as Pan troglodytes, Equus caballus, Cavia porcellus, Loxodonta africana, Mus musculus and Rattus norvegicus, and showed very similar gene structures. Moreover, the CLPSL3 contained 18 highly conserved cysteines in all species, suggesting that it might relate to the disulfide bond formation.Colipase is a co-factor needed by pancreatic lipase for efficient dietary lipid hydrolysis. …”
Get full text

An spike-accum® bioconjugate protein vaccine confers potent SARS-CoV-2-specific immunity by Jean Pierre Bikorimana, Nathanael A. Caveney, Nehme EL-Hachem, Gabrielle A. Mandl, John A. Capobianco, Daniela Stanga, Jamilah Abusarah, Mark A. Hancock, Roudy Farah, Marina P. Gonçalves, Darryl Falzarano, Mingmin Liao, Glenn Hamonic, Qiang Liu, Simon Beaudoin, Sebastien Talbot, Moutih Rafei

Get full text

Contemporary contexts of higher medical education development: Patient-centred care in medical students’ understanding by T. D. Podkladova, L. G. Smyshliaeva, A. O. Okorokov, I. I. Soshenko

“…The research methods include theoretical, phenomenological, and structural types of analysis; survey method, expert assessments, and focus groups.Results. …”
Get full text

Morphofunctional Characteristics of the Hippocampus of White Rats in the Acute Period After Severe Traumatic Brain Injury During the Use of L-lysine Aescinat by I. P. Koshman, A. Yu. Shoronova, S. S. Stepanov, A. G. Kalinichev, V. A. Akulinin, A. S. Stepanov, D. B. Avdeyev, V. L. Molchanova

“…The revealed changes are considered not only as patho-, but also as sanogenetic structural mechanisms of protection and reorganization of the hippocampus in the acute post-traumatic period.1. …”
Get full text

Extracellular Vesicles Present in Bone Marrow Mesenchymal Stromal/Stem Cell Conditioned Media Restore Spermatogenesis in Azoospermic Mice by Rano Zhankina, Afshin Zare, Alireza Afshar, Arezoo Khoradmehr, Mohammad Reza Dorvash, Farhad Rahmanifar, Nader Tanideh, Omid Koohi Hosseinabadi, Ali Arabi Monfared, Shahrokh Zare, Nadiar Mussin, Asset Askerovich Kaliyev, Ulanbek Zhanbyrbekuly, Amin Tamadon

“…Additionally, protein structure extraction, protein-protein docking analysis, and data visualization were conducted.Results: Histomorphometry and flow cytometry showed that most seminiferous tubules in the therapy groups exhibit­ed normal morphology and restored spermatogenesis, unlike the azoospermia group. …”
Get full text

Results of modern radiation-hygienic surveys of settlements of Bryansk Oblast of the Russian Federation bordering the Republic of Belarus. Part 1: Characteristics of the settlement... by I. K. Romanovich, A. B. Bazyukin, A. N. Barkovsk, A. M. Biblin, A. A. Bratilova, G. Ya. Bruk, K. V. Varfolomeev, A. V. Gromov, E. A. Drozdova, T. V. Zhesko, S. A. Ivanov, M. V. Kaduka, T. A. Kormanovskaya, O. S. Kravtsova, V. A. Nekrasov, V. P. Ramzaev, K. A. Saprykin, N. V. Titov, O. A. Isakov, E. I. Zlotnikova, A. G. Sosnitskiy, V. I. Filin, A. V. Kudryashov, A. A. Ladik, V. A. Lalayan

“…The modern demographic composition of the population is considered; the structure of private subsidiary plots is investigated. …”
Get full text

Pre-clinical allergenicity assessment of IgE epitope-targeted Der p 2 mutants demonstrate potential as hypoallergenic AIT candidates by Glorismer Pena-Amelunxen, Mohadeseh Asghari, Kriti Khatri, Jill Glesner, Serge A. Versteeg, Serge A. Versteeg, Ronald van Ree, Ronald van Ree, Martin D. Chapman, Scott A. Smith, Maksymilian Chruszcz, Anna Pomés, Lorenz Aglas, Lorenz Aglas, Lorenz Aglas

Get full text

Deep learning and genomic best linear unbiased prediction integration: An approach to identify potential nonlinear genetic relationships between traits by F. Shokor, P. Croiseau, H. Gangloff, R. Saintilan, T. Tribout, T. Mary-Huard, B.C.D. Cuyabano

“…Deep learning (DL) offers a promising alternative for capturing nonlinear genetic relationships due to its ability to identify complex patterns without prior assumptions about the data structure. We proposed a novel hybrid model that that combines both DL and GBLUP (DLGBLUP), which uses the output of the traditional GBLUP, and enhances its predicted genetic values (PGV) by accounting for nonlinear genetic relationships between traits using DL. …”
Get full text

HKU5 bat merbecoviruses engage bat and mink ACE2 as entry receptors by Mia Madel Alfajaro, Emma L. Keeler, Ning Li, Nicholas J. Catanzaro, I-Ting Teng, Zhe Zhao, Michael W. Grunst, Boyd Yount, Alexandra Schäfer, Danyi Wang, Arthur S. Kim, Aleksandra Synowiec, Mario A. Peña-Hernández, Samantha Zepeda, Ridwan Arinola, Ramandeep Kaur, Bridget L. Menasche, Jin Wei, Gabriel A. Russell, John Huck, Jaewon Song, Aaron Ring, Akiko Iwasaki, Rohit K. Jangra, Sanghyun Lee, David R. Martinez, Walther Mothes, Pradeep D. Uchil, John G. Doench, Alicen B. Spaulding, Ralph S. Baric, Leonid Serebryannyy, Yaroslav Tsybovsky, Tongqing Zhou, Daniel C. Douek, Craig B. Wilen

Get full text

Synthesis, physical-chemical and biological properties of 1,8-disubstituted compounds of theobromine. III. 8-Amino-p-chlorobenzyltheobromines by D. G. Ivanchenko, M. I. Romanenko, A. M. Kamyshny, N. M. Polishchuk

“…There have been developed available laboratory-based methods for the synthesis of 8-aminosubstituted 1-p-chlorobenzyltheobromine, the structure of which has been proved by data obtained from elemental analysis and NMR- spectroscopy. …”
Get full text

Adherence to Medical Treatment in Elderly Patients with Coronary Artery Disease in the Settings of Primary Outpatient Care by S. K. Zyryanov, S. B. Fitilev, A. V. Vozzhaev, I. I. Shkrebneva, N. N. Shindryaeva, D. A. Klyuev, L. N. Stepanyan, A. M. Lutsenko, A. T. Tsai, A. A. Danilova

“…Medical history and structure of pharmacotherapy do not influence level of adherence in this population. …”
Get full text

The Attitude of Pregnant Women and Health Workers for Influenza Vaccination by N. I. Briko, T. S. Saltykova, A. N. Gerasimov, A. A. Pozdnyakov, E. B. Brusina, L. P. Zueva, A. V. Lyubimova, A. A. Golubkova, T. G. Suranova, T. V. Tolokonnikova, V. B. Turkutyukov, V. I. Shumilov, V. A. Kalinkina, O. V. Kovalishena, L. D. Belotserkovtsova

“…Influenza and ARVI - the main nosological form in structure of all infectious diseases. Influenza is especially dangerous to pregnant women. …”
Get full text

Territorially Stratified Modeling for Sustainable Management of Free-Roaming Cat Populations in Spain: A National Approach to Urban and Rural Environmental Planning by Octavio P. Luzardo, Ruth Manzanares-Fernández, José Ramón Becerra-Carollo, María del Mar Travieso-Aja

“…These data were stratified by municipal population size and applied to national census figures to generate a model-ready demographic structure. We then implemented a stochastic simulation using Vortex software to project long-term population dynamics over a 25-year horizon. …”
Get full text

Modeling the Meaning of Individual Words Using Cultural Cartography and Keystroke Dynamics by Tatiana A. Litvinova, Olga V. Dekhnich

“…The material of the study is a newly developed dataset containing associative reactions to the keywords of Russian culture, anonymized data about the informants, as well as the reaction time while producing associations measured using a program that records keystrokes. The proposed research methodology includes both the existing approaches (automatic extraction of relations from texts based on data from language models and methods of vector semantics, i.e., “cultural cartography using word embeddings”) and a new list of features developed by the authors to describe individual differences in the meaning of a word based on the data from neurobiology about the meaning structure of word. …”
Get full text