Repurposing Rafoxanide: From Parasite Killer to Cancer Fighter by Teresa Pacifico, Lorenzo Tomassini, Livia Biancone, Giovanni Monteleone, Carmine Stolfi, Federica Laudisi

“…Rafoxanide exerts its anticancer activity through multiple complementary mechanisms, including the induction of endoplasmic reticulum stress, cell cycle arrest, apoptosis, and immunogenic cell death. …”
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Nutrient Availability Alters the Effect of Autophagy on Sulindac Sulfide-Induced Colon Cancer Cell Apoptosis by Shiun-Kwei Chiou, Neil Hoa, Lisheng Ge, Martin R. Jadus

“…Induction of autophagy under various cellular stress stimuli can lead to either cell survival or cell death via apoptotic and/or autophagic (nonapoptotic) pathways. …”
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Comparative study: trimetazidine versus olanzapine on cognitive dysfunction and behavioral changes in ketamine-induced psychosis model in mice by Yosra Magdy, Sherif Kamar, Hoda Fansa, Sara Khedr, Amina Sedky

“…Abstract Background Mitochondrial dysfunction and oxidative stress may contribute to schizophrenia. Negative symptoms and cognitive dysfunction in individuals with schizophrenia are resistant to anti-psychotic medications, but physical exercise is an effective treatment. …”
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Frictional Experiments on Granitic Faults: New Insights into Continental Earthquakes and Micromechanical Mechanisms by Huiru Lei, Shimin Liu, Wenhao Dai

“…The velocity-weakening regime shifts to higher temperatures with increasing slip velocity or decreasing pore fluid pressure. Temperature, normal stress, pore fluid pressure, and slip velocity interact to modulate frictional stability. …”
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Age-Related Alterations in the Expression of Genes and Synaptic Plasticity Associated with Nitric Oxide Signaling in the Mouse Dorsal Striatum by Aisa N. Chepkova, Susanne Schönfeld, Olga A. Sergeeva

“…Corticostriatal NO-dependent LTD induced by pharmacological activation of group I metabotropic glutamate receptors underwent significant reduction with aging and could be restored by inhibition of cGMP hydrolysis indicating that its age-related deficit is caused by an altered NO-cGMP signaling cascade. …”
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Physical modeling of glacier contact with bedrock (experiment) by V. P. Epifanov, A. F. Glazovsky, N. I. Osokin

“…Influence of shear to normal stresses ratio on the adhesive ice/substrate strength has been shown. …”
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Effects of Integrating Music Therapy into Family Support System on Adolescent Depression by Jie Zhou, Liying Liu, Lipeng Zheng

“…The ASLEC score showed a greater reduction in aspects such as interpersonal relationships, academic stress, punishment, and loss (P < 0.05). …”
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The potential of spirulina platensis to substitute antibiotics in broiler chickens diets: influences on growth performance, serum biochemical profiles, meat quality, and gut microb... by Bassam A. ALAHMADI

“…SPE (3 mg/kg) also reduced oxidative stress by decreasing malondialdehyde (MDA) levels while sustaining antioxidant enzyme levels. …”
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Behavior of arch composite beam: Experimental and numerical investigation by Abdelrahim Sabsabi, Oussama Baalbaki, Adnan Masri, Hassan Ghanem

“…Results demonstrated that external prestressing increased the ultimate moment capacity by 80 %, reduced mid-span deflection by 60 %, and significantly redistributed internal stresses, promoting a favorable arching effect. Furthermore, reducing the number of shear connectors by 50 % led to a 28 % reduction in stiffness and a 20 % increase in ductility, with negligible impact on ultimate load. …”
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P55 | ENDOTHELIAL THYMIDINE PHOSPHORYLASE DEFICIENCY TRIGGERS MORPHO-FUNCTIONAL DEGE-NERATION OF ENTERIC NEURONS AND REDUCES INTESTINAL STEM CELL PROLIFERATION

“…Immunofluorescence and live imaging revealed neurite fragmentation and increased glial and fibroblast proliferation, while neuronal counts remained stable. Stress features included neuronal swelling and elevated nNOS expression. …”
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Design of monoblock crossing for heavy operating conditions by P. V. Tregubchak

“…The lowest equivalent stresses are found in one of the monoblock crossing designs with two longitudinal stiffening ribs presented in the article. …”
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Mixed chronic scrotal pain secondary to piriformis scarring treated with PRF: case report by Fangfang Ding, Fengqi Fan, Feng Ji, Hua Xu

“…The therapeutic strategy synergistically addressed all three cascades of mechanisms via C-fiber modulation, reduction of pro-inflammatory cytokines, and reversal of neuroplasticity. …”
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Topological optimization design of the front coupling rod of prosthetic knee joint based on Inspire by Xiaofei Su, Yan Zhu, Hui Dong, Jingyu Yang, Lu Wang, Zhengyu Zhao

“…This optimization process is aimed at achieving mass reduction of the prosthetic motion mechanism while improving its structural performance. …”
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Can Yoga Help to Manage the Symptoms of Thyroid Diseases? by Chakraborty Amrita, Mukherjee Mitali, Choudhary Swati Kumari, Kumar Rupesh

“…Studies revealed a trend toward balance in thyroid hormone, reduction in psychological symptoms such as stress, anxiety, and depression, and improvement in the quality of life of thyroid patients through Yoga. …”
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BIOMECHANICAL RATIONALE OF AN EARLY DENTURE CHOISE IN PROSTHETICS OF BOUNDED DEFECTS OF DENTAL ROWS by R.V. Petrenko, A.H. Fenko, A.I. Petrenko, K.V. Marchenko, V.N. Dvornik, A.P. Pavlenko, V.D. Kindii

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Novel Endoscopic‐Assisted Long Plate Approach for Mandibular Condylar Fracture Reconstruction—A Preliminary Study by Chao‐Hsin Huang, Chia‐Chen Lee, Yi‐Chia Wu, Hsiao‐Chen Lee, Yur‐Ren Kuo, Su‐Shin Lee

“…Specifically, the average operation time for the group treated with closed reduction and intermaxillary fixation was 250 min, for Group B cases treated with short plate open reduction and intermaxillary fixation was 429 min, and for Group C treated with long plate open reduction and intermaxillary fixation was 413 min. …”
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Factors Affecting Eating Motivation Play a Role in Orthorexia Nervosa in University Students: A Cross-Sectional Study by Rabia Melda Karaağaç, Indrani Kalkan

“…Interventions should address this balance by promoting a holistic approach to nutrition, integrating stress management techniques, and raising awareness of ON through targeted workshops and educational programs for students and health professionals. …”
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Covid-19 Pandemic and Students Performance in Selected Secondary Schools in Rukungiri District. by Ainemigisha, Prossy

“…The findings highlighted the critical role of transitioning to digital platforms, stressing the need for educational institutions to ensure the quality and effectiveness of online instructional methods, in line with literature on the challenges of global crises. …”
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Application and evaluation of the technical condition of composite materials in aircraft and unmanned aerial vehicles by acoustic emission method of nondestructive testing by A. V. Popov, A. O. Samuylov, I. S. Cherepanov

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Single nuclei RNA-sequencing unveils alveolar macrophages as drivers of endothelial damage in obese HFpEF-related pulmonary hypertension by Era Gorica, Jacopo Spezzini, Iliana Papadopoulou, Marialucia Telesca, Valeria Masciovecchio, Shafeeq A. Moahmmed, Alessandro Mengozzi, Hung-Wei Cheng, Natalia Atzemian, Ludovica Di Venanzio, Alessia Mongelli, Omer Dzemali, Vincenzo Calderone, Francesco Paneni, Christian M. Matter, Burkhard Ludewig, Frank Ruschitzka, Sarah Costantino

“…In vitro experiments were performed to study the mechanisms underlying metabolic stress-induced macrophage dysfunction using palmitic acid (PA), co-culture experiments were used to investigate the crosstalk between macrophages and endothelial cells. …”
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