M.U.P.S (Medically Unexplained Physical Symptoms): Is the Accurate Diagnosis Necessary for the Rehab-Team? by Avi Ohry, Atzmon Tsur

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Optimization analysis of ingate supporting structure under the condition of thick loose layer and thin bedrock by Jihao FENG, Chuanxin RONG, Hao SHI, Chengtao LI, Gangjian AN

“…Following optimization of the support scheme, there is a reduction observed in the maximum principal stress of the ingate lining, vertical settlement displacement in the overlying thin bedrock, and plastic zone volume of the support structure. …”
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Understanding creep behavior of polycrystalline TiAl alloys by molecular dynamics simulations by Yunlou Wang, Hangyu Yue, Xinying Xu, Zhenquan Liang, Hongwu Gao, Rengeng Li

“…The results demonstrated that the minimum creep rate exhibited an increase and the creep life showed a reduction as the creep temperature/stress increased. …”
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NANOVESICLES IN THE GUT–BRAIN AXIS: INSIGHTS FROM PROBIOTIC SUPPLEMENTATION IN IRRITABLE BOWEL SYNDROME

“…To further explore the mechanistic effects of probiotics, HT29 intestinal epithelial cells were treated with the probiotic mix in the presence (or not) of hydrogen peroxide (H₂O₂) for inducing oxidative stress. The supplementation with the same probiotic mix used in the in vivo study exhibited a marked cytoprotective effect by attenuating the H₂O₂-induced stress response: e.g., probiotic exposure led to a significant reduction of HSP60 protein levels and to a restoration of tight junction proteins, putatively contributing to preserving/remodeling the epithelial barrier integrity. …”
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Herbivore functions in the hot-seat: Resilience of Acanthurus triostegus to marine heatwaves. by Taylor Souza, Jeroen Brijs, Leon Tran, Larry Crowder, Jacob L Johansen

“…Given marine heatwaves can last for weeks to months, these results indicate that while herbivorous coral reef fishes may continue to remove algae during periods of thermal stress, their ability to control many macroalga may be limited due to precipitous reductions in individual performance. …”
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ANGIOTENSIN II RECEPTOR ANTAGONISTS AND ACE INHIBITORS: OPTIMIZATION OF CHOICE FOR TREATMENT OF CARDIOVASCULAR DISEASES by E. M. Khurs, A. V. Poddubnaya

“…On the other hand ramipril had priority at advanced stage of CVC (reduction in systolic diameter-thickness ratio, LV hypertrophy, myocardial stress and myocardial stiffness). …”
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STRENGTH SIMULATION AND TOPOLOGY OPTIMIZATION DESIGN OF OFF-ROAD VEHICLES’ HUB MOTOR HOUSING by QI Chang, MA Yuanhang, YANG Lining, YANG Shu, WANG Bolong

“…The results indicate that compared to the existing design,the optimized hub motor housing structure experiences a stress reduction of over 40% and a weight reduction of 2.6%. …”
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THE ROLE OF GENETICALLY DETERMINED BODY RESISTANCE OF WARM-BLOODED ANIMALS TO HYPOXIA IN THE REALIZATION OF EFFECTOR FUNCTIONS OF NEUTROPHILS IN THE MODEL OF ADJUVANT-INDUCED RHEUM... by Elena Georgievna Pukhaeva, Alibek Kirilovich Badtiev, Fatima Elbrusovna Salamova, Stanislav Georgievich Dzgoev, Alina Muratbekovna Kupeeva

“…Given that human and animal populations are genetically heterogeneous in terms of the body's resistance to oxygen deficiency, the modern approach to predicting and treating diseases associated with impaired immune regulation requires taking into account the role of hypoxia in the implementation of pathogenetic mechanisms of inflammation. …”
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Red cell distribution width-to-platelet ratio (RPR) as a predictor of prolonged stay at hospital for COVID-19 inpatients by Martha Fors, Santiago J. Ballaz

“…One exemption was the red cell distribution width-to-platelet ratio (RPR) index, which can increase the probability of a longer hospital stay by up to ten times (HR(IC95%) = 0.092(0.03-0.29); p < 0.001).Conclusion The most effective biomarker to identify COVID-19 patients at high risk for extended hospital stay was RPR.Highlights IntroductionDetermining hospital Length of Stay (LoS) is vital for resource management, especially for future COVID-19 outbreaks.Previous studies have primarily focused on sociodemographic and clinical attributes, along with resource availability, but have not accounted for other factors like routine laboratory tests, which can significantly impact LoS predictions.This study examines novel hematology scores as predictors of LoS, emphasizing their importance in resource-limited settings like Ecuador.MethodsThis retrospective cohort study analyzed 2,930 COVID-19 patients admitted to Hospital IESS Quito Sur in Ecuador focusing on confirmed cases with complete blood count (CBC) values to assess LoS.The study explored various hematological ratios, such as the neutrophil-to-lymphocyte ratio (NLR) and red cell distribution width-to-lymphocyte ratio (RLR), as potential predictors of LoS and in-hospital outcomes for COVID-19 patients, using a combination of univariate and multivariable Cox proportional hazards regression models.Kaplan-Meier survival estimates and log-rank tests were used to analyze survival and discharge probabilities over time, highlighting sex-dependent effects and the significant association between selected hematological indices and patient outcomes.ResultsThe mean LoS for survivors was significantly shorter compared to those who died (p < 0.001), indicating that longer hospitalization was associated with higher mortality risk.Women had a shorter average LoS (with lower mortality risk (p < 0.001), suggesting an asymmetrical hospitalization pattern based on sex.While most hematological markers had minimal clinical relevance for LoS, the red cell distribution width-to-platelet ratio (RPR) stood out, increasing the likelihood of a longer hospital stay by up to tenfold, making it a critical factor in predicting prolonged hospitalization.DiscussionMen had longer hospital stays and higher mortality rates than women, likely due to differing inflammatory responses, though hyperinflammation markers like NLR, PLR, and Leu-CPR had minimal clinical impact.RPR had the strongest link to longer hospital stays, indicating a higher risk of extended hospitalization in severe COVID-19 cases.Elevated RPR is tied to oxidative stress and coagulation issues, suggesting early identification could help reduce prolonged stays and complications.ConclusionResearch generally points to clinical complications from COVID-19 as the main factor behind prolonged hospitalizations, underlining the importance of early identification and management of these issues.…”
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H3K4me3 binding ALFIN-LIKE proteins recruit SWR1 for gene-body deposition of H2A.Z by Linhao Xu, Yafei Wang, Xueying Li, Qin Hu, Vanda Adamkova, Junjie Xu, C. Jake Harris, Israel Ausin

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The role of Cultural Socialization and Contextual Factors on the Subjective Well-Being of Immigrant Adolescent Girls at the Beginning and End of Adolescence: A life course perspect... by Elaheh Hejazi, Ahmad Baseri, Zahra Naghsh, simin ebrahimi

“…Hierarchical data analysis revealed that cultural socialization and speaking the mother tongue were significant predictors of subjective well-being, whereas educational level demonstrated a comparatively weaker predictive role. …”
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Effects of rates of consolidation on low-carbon solidification of marine deposits with recycled ISSA and GGBS by Ze-Jian Chen, Run-Dong Zhao, Hao-Yu Fang, Wen-Bo Chen, Rong-Jun Zhang, Jian-Hua Yin

“…Consolidation-solidification achieves higher volume reduction and yielding stress than pure solidification. …”
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Creep constitutive model of strain energy density considering the whole process of creep deformation. by Yuemei Li

“…The continuous medium strain energy theory is used to analyze the sudden change process of creep macroscopic mechanical behavior, and the critical strain energy density value is defined as the control parameter to predict the occurrence time of accelerated creep. …”
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Modelos de materiales hiperelásticos para el análisis de los elastómeros usando el MEF. by R.A. González Carbonell, E. Álvarez García, J. L. Moya Rodríguez

“…Finalmente se explica como determinar los valores de las constantes del modelo hiperelástico.This researching deals with the material models used by Finite Elements software to predict the behavior of the stress and strain of hyperelastic materials. …”
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Genome-wide study and expression analysis of soybean ERF transcription factors and overexpression of GmERF205 enhances drought resistance in soybean by Nan Wu, Yongqi Feng, Tao Jiang, Zhaobo Li, Yulan Liu, Minghao Yuan

“…Furthermore, we predicted that this transcription factor would be localized in the nucleus, a hypothesis that was confirmed by subcellular localization experiments. …”
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Retention Challenges in Opioid Use Disorder Treatment: The Role of Comorbid Psychological Conditions by David C. Seaberg, Jamie McKinnon, Lyn Haselton, Patrick Palmieri, Jason Kolb, Suman Vellanki, Mary Moran, J. Chika Morah, Nicholas Jouriles

“…Baseline surveys indicated moderate symptom severity for depression and anxiety. The Post-Traumatic Stress Disorder Checklist (PCL-5) scores showed significant traumatic stress. …”
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General practitioners' perceptions of the burden of RSV and views on RSV immunisation – a qualitative interview study by Sarah F. Hak, Roderick P. Venekamp, Tamara Platteel, Louis J. Bont, Joanne G. Wildenbeest, Sibyl Anthierens

“…This drives a general assumption of low disease burden in older adults and low perceived need for RSV immunisation. GPs stress the need for targeted education on RSV epidemiology and immunisation options to better guide (parental) decision-making. …”
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Wind speed and soil properties drive the height-diameter allometric pattern of island plants by Chengfeng Yang, Renfu Liao, Shengzhuo Huang, Yikang Cheng, Shurong Zhou

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Evaluation of Caregiving Burden in Caregivers of Children with Chronic Disease by Murat Doğan, Utku Özer, Tuğçe Kalın, Yılmaz Seçilmiş, Mehmet Adnan Öztürk

“…In those with moderate to severe care burden, later disease development and economic difficulties were greater and education levels were lower (p<0.05).Conclusion:Care burdens should be reduced by providing more economic and social support to those who care for the child with chronic disease and by educating healthcare professionals on issues such as disease management, problem solving and coping with stress.…”
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Exploring dietary perception, beliefs and practices among pregnant adolescents, their husbands and healthcare providers in West Arsi, Central Ethiopia: a phenomenological study by Adane Tesfaye, Tefera Belachew, Dessalegn Tamiru, Yohanness Addisu Wondimagegne

“…Husbands’ involvement in nutrition education and specific nutrition training for healthcare providers are the other facilitators identified in this study. …”
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