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IL-4 and IL-13 in Cardiovascular Disease: From Immune Modulation to Therapeutic Possibilities – A Narrative Review
Published 2025-08-01“…Ahmet Turhan Kılıç,1 Rıdvan Bora,2 Burak Toprak1 1Department of Cardiovascular Surgery, Mersin City Education and Research Hospital, Mersin, Turkey; 2Department of Cardiology, Tarsus State Hospital, Mersin, TurkeyCorrespondence: Burak Toprak, Department of Cardiovascular Surgery, Mersin City Education and Research Hospital, Kuzeykent District, 31131 Street No: 1, Floor: 6, Flat No: 11, Yenişehir, Mersin, 33120, Turkey, Email brk.tprk@gmail.comBackground: Interleukin-4 (IL-4) and Interleukin-13 (IL-13) are central regulators of the Th2 immune response and play pivotal roles in vascular inflammation, endothelial dysfunction, and cardiovascular remodeling. …”
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Dual-targeted siRubicon delivery strategy triggers hepatocellular lipophagy for mitigating liver steatosis
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Parents’ State and Trait Anxiety Levels During Bloodletting Attempts in the Pediatric Emergency Department
Published 2025-08-01“…Introduction: Parental stress and anxiety during pediatric bloodletting in the pediatric emergency department (PED) are influenced by a complex interplay of factors, including the child’s medical condition, unfamiliarity with procedures, healthcare-provider interactions, and parental knowledge gaps. …”
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Influence of academic-professional hardiness on the subjective well-being of students in socionomic professions
Published 2023-11-01“…The obtained results allow refining the understanding of educational and professional resilience as a predictor of students’ psychological well-being in helping professions through productive coping styles, as well as outlining approaches to developing and implementing programmes for enhancing academic and professional hardiness among students in socionomic fields of education (such as pedagogy and education, psychology, social work, medicine). …”
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Ecological testing of winter and spring barley varieties in arid conditions of the Republic of Kalmykia
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Prevalence of depression among university students in China: a systematic review and meta-analysis
Published 2025-04-01“…Medical students and those in high-stress regions warrant prioritized interventions. …”
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The worldview of Akkermansia muciniphila, a bibliometric analysis
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A novel anthropometric method to accurately evaluate tissue deformation
Published 2025-07-01“…However, displacement from movement affects alignment so accurately measuring tissue deformation with different wear conditions becomes challenging.MethodsTo address this issue, an analytical model is constructed to predict tissue deformation by using the Boussinesq solution, which is based on the elastic theory and stress function method. …”
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Modulating effect of glutathione (GSH) on 2,4-dichlorophenoxyacetic acid (2,4-D) toxicity
Published 2025-08-01“…The results confirmed the validity of the hypothesis that oxidative stress induction is a molecular mechanism of 2,4-D toxicity and genotoxicity. …”
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Hajj in sweltering summer season and heat stroke
Published 2024-08-01“…However, the mitigation strategies implemented did cause a significant reduction in heat stroke cases (74.6%), and (47.6%) in case fatality rate7. …”
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The comparative effects of ventilation shutdown with heat (VSDH), relative humidity (VSDHRh), or CO2 (VSDCO2) on broiler electroencephalogram (EEG), blood chemistry and gene expres...
Published 2025-09-01“…Phase 2 (P2) looked at the progression of the stress parameters over time with specific physiological points when birds were removed from their respective chamber. …”
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Ivabradine induces RAD51 degradation, potentiating PARP inhibitor efficacy in non-germline BRCA pathogenic variant triple-negative breast cancer
Published 2025-08-01“…FBXO24 mediates RAD51 protein degradation via the ubiquitin-proteasome system. The reduction of RAD51 expression contributes to the feature of BRCAness. …”
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Unveiling the multifaceted roles of anthocyanins: a review of their bioavailability, impacts on gut and system health, and industrial implications
Published 2025-01-01“…Ultimately, we advocate high-throughput analysis coupled with computational approaches such as AI-driven predictive modeling of anthocyanin-microbiota interactions to elucidate structure-activity relationships. …”
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Research on the evolution mechanism of shale mechanical properties under variable bedding angles
Published 2025-03-01“…This leads to incorrect prediction of fracturing parameters, which results in inefficient fracturing reconstruction of shale reservoir. …”
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Creep constitutive model of 7050⁃T7451 aluminum alloy based on damage mechanics
Published 2025-05-01“…Based on the comparative analysis of the test results and the predicted results, it was verified that the established physical constitutive model can accurately describe the creep behavior of 7050 aluminum alloy under different temperatures and stresses.…”
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