Effect of bio-psychosocial nursing intervention on emotional status, body image, and quality of life of women with polycystic ovarian syndrome: a quasi-experimental study by Hanaa M. Abo Shereda, Eman A. Shokr, Hanaa A. Radwan, Doaa Lotfi Afifi Alqersh, Shereen Roushdy Hashem, Ashraf Mohamed El-Saiyed Konsouh, Zeinab A. Kasemy, Hanan E. Nada

“…It frequently results in emotional stress, a low quality of life, and body image issues. …”
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Autocrine interferon poisoning mediates ADAR1-dependent synthetic lethality in BRCA1/2-mutant cancers by Roman M. Chabanon, Liudmila Shcherbakova, Magali Lacroix-Triki, Marine Aglave, Jean Zeghondy, Victor Kriaa, Antoine Gougé, Marlène Garrido, Elodie Edmond, Ludovic Bigot, Dragomir B. Krastev, Rachel Brough, Stephen J. Pettitt, Thibault Thomas-Bonafos, Robert Samstein, Christophe Massard, Marc Deloger, Andrew NJ Tutt, Fabrice Barlesi, Yohann Loriot, Suzette Delaloge, Marcel Tawk, Cindy Degerny, Yea-Lih Lin, Barbara Pistilli, Philippe Pasero, Christopher J. Lord, Sophie Postel-Vinay

“…Abstract ADAR1 is an RNA editing enzyme which prevents autoimmunity by blocking interferon responses triggered by cytosolic RNA sensors, and is a potential target in immuno-oncology. However, predictive biomarkers for ADAR1 inhibition are lacking. …”
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Impaired DNAJB2 Response to Heat Shock in Fibroblasts from a Neuropathy Patient with <i>DNAJB2/HSJ1</i> Mutation: Cystamine as a Potential Therapeutic Intervention by Raj Kumar Pradhan, Nikolas G. Kinney, Brigid K. Jensen, Hristelina Ilieva

“…While homozygous mutations in DNAJB2/HSJ1 have been linked to early-onset neuropathy, a heterozygous DNAJB2 c.823+6C>T was discovered in an adult patient with severe sensory–motor polyneuropathy. This mutation is predicted to affect both isoforms of the protein. DNAJB2 (HSP40), a key member of the heat shock protein family, plays a critical role in cellular protection and stress, including response to heat shock. …”
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Hemodynamic assessment of rupture risk during growth stages in middle cerebral artery aneurysms treated with coiling by Rifaqat Ali, Hana Ihsan Hassan, Aman Sharma, Aashim Dhawan, P. Sharma, Waam Mohammed Taher, Mariem Alwan, Ali Fawzi Al-Hussainy, Mahmood Jasem Jawad, Hiba Mushtaq

“…In contrast, coiling consistently suppressed these metrics across all volumes: peak WSS fell below 100 Pa, average WSS remained under 5 Pa, and OSI was reduced to below 0.03. AWSS and OSI reductions indicated dampened flow oscillations and reduced biomechanical stress. …”
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Loudness Assessment of Musical Tones Equalized in A-weighted Level by Despina KLONARI, Konstantinos PASTIADIS, Georgios PAPADELIS, George PAPANIKOLAOU

“…Consequently, the use of elaborate computational prediction is stressed, in view of the necessity for thorough investigation of factors affecting the perception of loudness of musical sounds.…”
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Perioperative factors influencing post-appendectomy outcomes in adults: a single-center prospective study in the North of Palestine by Alaa Zayed, Khaled Demyati, Abdulsalam Alkaiyat, Alaa Omari, Eliana Masri, Zain Saqfalhait, Yazan.N.A.Abdallah, Obayda Darawsha, Mohammed Hajhamad

“…Furthermore, the significant role of anxiety and depression in post-operative outcomes suggests that stress-reduction strategies and mental health support should be integrated into patient care. …”
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Modelos de materiales hiperelásticos para el análisis de los elastómeros usando el MEF // Hyperelastic material models for the analysis of elastomers by using FEM. by R. A. González Carbonell, E. Álvarez García, J. L. Moya Rodríguez, K. Abreu González

“…</p><p>____________________________________________________________________________</p><p>Abstract<br />This researching deals with the material models used by Finite Elements software to predict the<br />behavior of the stress and strain of hyperelastic materials. …”
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Domain knowledge-driven decomposition-based large-scale optimization for ship cabin structures by Puyu JIANG, Jun LIU, Qiangjun LUO, Yuansheng CHENG

“…Due to the monotonicity and locality of each bending stress, shear stress, and deformation constraint, subproblems with larger constraint margins are prioritized for optimization. …”
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Modelling and Production of Injection Moulded Polyvinylchloride--Sawdust Composite by C.O. Aliyegbenoma, J.A. Apkobi, D.D. Olodu

“…The values obtained from the validation of these models were therefore found to be satisfactory, and shows good predictability of the model and its adequacy. Keywords: Composite, Modeling, Polyvinylchloride, Sawdust. …”
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Mechanical Effects of Lining Thinning in Shallow Four-Track High-Speed Railway Tunnels: Field Monitoring and Numerical Analysis by Shaohui He, Bo Jiang, Jianfei Ma

“…The actual rock pressure in the XBS Tunnel was significantly lower than theoretical predictions, and the tunnel primarily experienced genuine pressure rather than loosening pressure during construction, with the secondary lining serving as a safety reserve. …”
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Research on the influence of epoxy resin on the service life of bond wire in power devices by HUA Wenbo, DENG Erping, LIU Peng, NIU Hao, YANG Shaohua, DING Lijian

“…Then, for the 1 200 V, 25 A TO devices used in the experiment, a coupled finite element model of electrical-thermal-stress multiphysics was established using COMSOL simulation software to explore the different thermal expansion coefficients before and after the glass transition temperature (<italic>T</italic>_g) of epoxy resin and the influence of different thickness parameters of epoxy resin on the stress strain of bonding wire, and the service life of bonding wire was predicted by combining the fatigue model. …”
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The method for impact analyzing of duplex plasma nitriding and DLC coatings on the cyclic performance of 16MnCr5 piston pin steel under plain and fretting fatigue testing by Mobin Dizisaz, Mohammad Sadegh Aghareb Parast, Mohammad Azadi

“…For the linear regression model analyzing all logarithmic fatigue data, the R² was 92.87 %, the Adjusted R² was 90.75 %, and the Predicted R² was 82.76 %.…”
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Antibacterial Evaluation of Tricyclic Antidepressants Against <i>S. aureus</i> and the Possible Pathways of the Mechanism of Action by Vitória Pessoa de Farias Cabral, Daniel Sampaio Rodrigues, Lívia Gurgel do Amaral Valente Sá, Lara Elloyse Almeida Moreira, Cecília Rocha da Silva, João Batista de Andrade Neto, Érica Rayanne Mota da Costa, Thais Lima Ferreira, Leilson Carvalho de Oliveira, Beatriz Oliveira de Souza, Dávylla Rênnia Saldanha Pinheiro, Bruno Coêlho Cavalcanti, Islay Lima Magalhães, Manoel Odorico de Moraes, Hélio Vitoriano Nobre Júnior

“…The mechanism of TCAs, isolated and combined with OXA, was associated with a reduction in cell viability, resulting from their action on the bacterial genetic material and generation of oxidative stress. …”
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An Exploratory Study Into the Effects of Regular Cold‐Water Sea Swimming on Daily Indices of Mental Health by Jill Forsten, Mark A. Wetherell

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Effects of Source Directivity and Nonlinear Soil Behavior During the January, 1 2024 Noto Earthquake (Mw = 7.5) by Pavlenko Ol'ga

“…In this research, based on KiK-net vertical array records (11 sites), models of soil behavior in the near-fault zones of the 2024 Noto earthquake are constructed, i.e. vertical distributions of stresses and strains in soil layers changing with time during strong motion, which showed nonlinear soil response and reduction of shear moduli in the near-fault zones. …”
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Overexpression of the STOX1B isoform of STOX1 triggers preeclampsia-like symptoms through HNF4α-dependent alterations of coagulation cascades in mice by Hélène Collinot, Louise Strubé, Ikram Benouda, Johan Castille, Sandrine Floriot, Nathalie Daniel-Carlier, Bruno Passet, Franck Lager, Isabelle Lagoutte, Gilles Renault, Benjamin Saintpierre, Maryline Favier, Djihane Djeridane, Céline Méhats, Francisco Miralles, Jean-Luc Vilotte, Daniel Vaiman

“…The two isoforms have opposite function on major genes involved in trophoblast syncytialization and oxidative stress management. Placenta-fetal overexpression of STOX1A induces preeclampsia in mice. …”
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Sphingosine 1-Phosphate Receptor 1 Is Required for MMP-2 Function in Bone Marrow Mesenchymal Stromal Cells: Implications for Cytoskeleton Assembly and Proliferation by Chiara Sassoli, Federica Pierucci, Alessia Tani, Alessia Frati, Flaminia Chellini, Francesca Matteini, Ambra Vestri, Giulia Anderloni, Daniele Nosi, Sandra Zecchi-Orlandini, Elisabetta Meacci

“…Notably, active S1PR1/MMP-2 signalling is required for F-actin structure assembly (lamellipodia, microspikes, and stress fibers) and, in turn, cell proliferation. Moreover, in experimental conditions resembling the damaged/regenerating tissue microenvironment (hypoxia), S1P/S1PR1 system is also required for HIF-1α expression and vinculin reduction. …”
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Is frequent handling with reinforcement effective in improving management practices for feedlot heifers? by Vitor R. Pacor, Messy H. A. Pantoja, Douglas H. S. Almeida, Isabela M. D. Batista, Milena S. Consorti, Cihan Çamakçı, Cristiane G. Titto

“… Aim of study: This study aimed to evaluate the effect of frequent handling of feedlot female cattle to decrease animal handling time and stress indicators. Area of study: Brazil, São Paulo State. …”
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Comparative study of LPBF Ta–Ti alloy: microstructural evolution and deformation behavior by Zhenyu Yang, Yuanhong Qiu, Jiangqi Zhu, Zhifeng Huang, Shengbin Dai, Weihu Yang, Min Liu, Gang Wang, Xingchen Yan, Wenhua Huang

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Aurones as new modulators of hypoxia inducible factor-1 (HIF-1) to prevent cardiac cell death by Léa Di Maria, Brayan Roulier, Morane Beaumet, Romain Haudecoeur, Ahcène Boumendjel, Elise Belaïdi, Basile Pérès

“…However, they exhibited divergent effects on HIF-1α expression: 2′- and 3′-hydroxyaurones led to a reduction, whereas 4′-hydroxyaurone caused an increase. …”
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