Dynamic Damage Mechanism of Coal Wall in Deep Longwall Face by Shuaifeng Lu, Sifei Liu, Zhijun Wan, Jingyi Cheng, Zhuangzhuang Yang, Peng Shi

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Chemoreactomic analysis of the antioxidant properties of vitamin B12 derivatives by I. Yu. Torshin, O. A. Gromova, L. A. Maiorova

“…The development of methods for predicting the properties of these molecules based on their chemical structure is important for the targeted organic synthesis of corrins with the desired properties and range of applications in pharmacology.Objective: chemoreactomic assessment of the antioxidant effects of vitamin B12 and its derivatives: aquacobalamin, diaquacobinamide, aquacyano-forms of heptaethanolamine-, heptaethylenediamine-, heptamethyl- and heptabutylcobyrinates.Material and methods. …”
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The role of peripheral blood microRNAs in the pathogenesis and treatment response of age-related macular degeneration by Meng Kong, Jingwen Li, Nianting Tong

“…This narrative review aims to summarize the involvement of peripheral blood microRNAs in the pathogenesis of AMD, focusing on key pathways such as oxidative stress, inflammation, and angiogenesis. Additionally, it explores their potential as biomarkers for predicting treatment response, particularly to anti-VEGF therapies. …”
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The influencing factors of depression among Chinese male nursing students: application of decision tree and FsQCA by Zenghui Wang, Jianxin Zhao, Hui Wang, Dongyu Song, Danjun Feng, Miao Yu, Feng Li

“…Results The trained decision tree demonstrated acceptable predictive performance (AUC = 0.78). The feature importance ranking placed self-esteem first, followed by childhood adversity, perfectionism, perceived stress, and insomnia. …”
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LIGHTWEIGHT DESIGN OF THE BASE FOR RECIPROCATING PISTON DIAPHRAGM PUMP BASE ON MULTI-OBJECTIVE OPTIMIZATION ALGORITHM by MA WenSheng, FENG ZhiWei, SHEN Yan, SUN ZhongZhi, NIU PeiYu, LIU ChunChuan, LI FangZhong, CHEN Tao

“…The lightweight design of diaphragm pump base structure has an important impact on the processing and production of diaphragm pump.Based on the research of the frame structure of a certain type of diaphragm pump,the equivalent model was established for the actual working environment and the finite element analysis was carried out.The design variables were defined according to analysis results to improve the calculation efficiency.The uniform test design method was adopted for the test design,and the relationship between the design variables and the stress and deformation was calculated through simulation fitting.The lightweight optimization mathematical model was established for the diaphragm pump base structure by using the multi-objective optimization algorithm.On the premise of meeting the performance requirements,some materials were reasonably configured,and the stress,deformation and natural frequency of the diaphragm pump base structure were as small as possible.The frame structure after the lightweight optimization design was simulated and analyzed,and compared with the structure before optimization.The results show that the structural properties of the engine base remain unchanged after lightweight,and the weight is reduced from 25372 kg to 24582 kg,with a weight reduction of 790 kg.The weight reduction effect is good,the maximum stress value is reduced by 45.1%,and the maximum deformation is reduced by 12.3%.The optimization effect is remarkable,which provides a basic support for the finite element analysis and lightweight optimization design of the new diaphragm pump structure.…”
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Targeting AKR1B1 inhibits metabolic reprogramming to reverse systemic therapy resistance in hepatocellular carcinoma by Qi Wang, Juan Liu, Ming Yang, Jun Zhou, Yaxuan Li, Jingjing Zheng, Hao Jia, Shuhua Yue, Yinpeng Le, Yuxin Su, Wenrui Ma, Ni An, Yunfang Wang, Jiahong Dong

“…The secretory nature of AKR1B1 not only underscores its predictive value but also facilitates the intercellular transmission of drug resistance. …”
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Range-wide climate risk and adaptive potential in a cold-water fish species by Mariah H. Meek, Nadya R. Mamoozadeh, Jeffrey C. Glaubitz, Matthew P. Hare, Clifford E. Kraft

“…Abstract Predicting extinction risk from climate change requires understanding adaptive variation and local adaptation across species’ ranges. …”
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Balancing Solar Energy, Thermal Comfort, and Emissions: A Data-Driven Urban Morphology Optimization Approach by Chenhang Bian, Panpan Hu, Chun Yin Li, Chi Chung Lee, Xi Chen

“…The prediction results outperform single-task models, achieving R² values of 0.710 (PVG), 0.559 (AUHII), 0.819 (IOD), and 0.405 (CEI), respectively. …”
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Evaluation of constitutive modeling for dynamic plastic-fracture modeling of dual phase (DP590) steel sheets by F. Najafnia, H. Talebi-Ghadikolaee, A.H. Bamdad, E. Dorchepour, R. Hashemi

“…In contrast, the normalized Cockroft-Latham model shows significant errors at higher stress triaxialities, making it less suitable for precise fracture predictions. …”
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Specificity and Selectivity of Raman Spectroscopy for the Detection of Dose‐Dependent Heavy Metal Toxicities by Isaac D. Juárez, Nicholas Shepard, Cole Sebok, Sudip Biswas, Endang Septiningsih, Dmitry Kurouski

“…We found these changes were specific to each HM, reflecting the activation of distinct stress‐response mechanisms. We also performed ICP‐MS of harvested rice tissue, allowing us to build Raman‐based calibration curves for predicting the HM concentration within rice. …”
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Influence of oral health status on absenteeism and presenteeism as indices of work productivity loss by Naoko Adachi, Kumiko Sugimoto, Hitomi Suzuki, Kayoko Shinada

“…Data on dental health and general health checkups were obtained from workers’ health records, and the workers responded to questionnaires on work productivity loss due to oral health problems, job stress, and oral health-related QOL. The odds ratio (OR) and 95% confidence interval (CI) for presenteeism and absenteeism were calculated using multiple logistic regression analyses of oral health status and oral health-related QOL adjusting with sex, age, educational background, occupation, job stress, current smoking, and hypertension. …”
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Investigation into the Rolling Process of 20CrNiMo/Incoloy 825 Composite Materials by Jie Liu, Hailian Gui, Peng Zhang, Chen Zhang, Hao Liu

“…The effects of rolling pass reduction and rolling speed on the warpage, interface strain difference, and stress of the 20CrNiMo/Incoloy 825 composite materials were evaluated, highlighting an ideal first-pass reduction of 30% and a rolling speed of 0.117 m/s. …”
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The WD40 gene family in recretohalophyte Limonium bicolor: genomic identification and functional analysis in salt gland development and salinity tolerance by Lu Sun, Huiying Mu, Yuqing Tan, Baoshan Wang, Xi Wang, Xi Wang, Fang Yuan, Fang Yuan

“…Although WD40 proteins are known regulators of plant stress responses, their roles in L. bicolor remain unexplored.MethodsWe performed a genome-wide analysis of WD40 genes in L. bicolor, including phylogenetic classification, subcellular localization prediction, cis-element analysis, and expression profiling during salt stress. …”
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Research on a PTSD Risk Assessment Model Using Multi-Modal Data Fusion by Youxi Luo, Yucui Shang, Dongfeng Zhu, Tian Zhang, Chaozhu Hu

“…The results show that the multi-modal data model is more accurate than the single data model, with significantly improved prediction ability. Zero-inflated Poisson models are prone to over-fitting when data is limited, while deep neural network models show superior performance in both training and prediction sets, especially the Hybrid LSTM-FCNN model, which not only has high accuracy but also strong generalization ability. …”
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Topology Optimization of a Robot Gripper with nTopology by Beatriz Monteiro, Francisca Rocha, Jose Costa

“…Fusion360 static stress analysis showed a reduction of 43% in weight, keeping the safety factor above 3, and leading to a displacement of 0,0067 mm. …”
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CLINICAL AND IMMUNOLOGICAL EFFICIENCY OF ADAMANTANE DERIVATIVE IN THERAPY OF ASTHENIC DISORDERS IN EARLY FORMS OF CHRONIC BRAIN ISCHEMIA by E. V. Davydova, A. V. Zurochka

“…When treating psychogenic asthenic syndrome in the veterans of recent  military  conflicts, an adamantane derivative  administered as a course  treatment, at a dose of 50 mg 2 times daily causes psychostimulant, anxiolytic, vegetotropic, antihypotymic, and hypnotic pharmacological effects, with reduction of main psychopathological and somatoneurological symptoms.A notable immunotropic effect  of the  drug  was revealed, being  expressed  as enhanced immunopoiesis; activation of innate defense  mechanisms; expansion of Treg lymphocyte population, suggestive for increased suppressor  effect  upon  the  mechanisms of autoimmune aggression;  implementation of cell differentiation/ proliferative effect; anti-apoptogenic properties; anti-inflammatory activity (reduction of TNFα, IL-8, hsCRP, along with IL-2  increase) associated with reduced functional activity of mononuclear cells; vasotropic action expressed  as normalized balance of vasoactive  factors  (nitric  oxide,  endothelin-1), decrease of nitrotyrosine concentration, suggesting  the  nitrosylation stress reduction. …”
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The Use of Germination Indices for Salinity Tolerance Classification of Pepper Cultivars by Gamze Kaya

“…Results showed that germination percentage decreased with increasing NaCl levels while the highest germination percentage at 20 dS/m was 92% in BT Burdem with no significant reduction. Seedling growth of pepper cultivars was severely inhibited by increasing salinity stress. …”
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Dual Cohort Insights Into Accelerometer‐Derived Weekend Warrior Physical Activity and Its Impact on Mortality by Rui Ren, Wenxu Wang, Qitong Liu, Xingyue Ye, Linze Xi, Ru Zhang, Liying Wang, Yao Zhang, Yanan Ma, Difei Wang

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Leadership and Mediation Approaches for Social Cohesion in the Greek Public Sector by Kyriaki Aravidou, Sotiria Triantari, Ioannis Zervas

“…Data were analyzed using Partial Least Squares Structural Equation Modeling (PLS-SEM) to test direct and indirect effects, evaluate the explanatory and predictive power of the model, and explore the mediation mechanisms linking leadership, mentorship, and digital tools to social cohesion. …”
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Fatigue Design Evaluation of Railway Bogie with Full-Scale Fatigue Test by Jung-Won Seo, Hyun-Moo Hur, Hyun-Kyu Jun, Seok-Jin Kwon, Dong-Hyeong Lee

“…Much study has been carried out in experimental and theoretical domains on the prediction of the structural integrity of the bogie frame. …”
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