Retention Challenges in Opioid Use Disorder Treatment: The Role of Comorbid Psychological Conditions by David C. Seaberg, Jamie McKinnon, Lyn Haselton, Patrick Palmieri, Jason Kolb, Suman Vellanki, Mary Moran, J. Chika Morah, Nicholas Jouriles

“…Baseline surveys indicated moderate symptom severity for depression and anxiety. The Post-Traumatic Stress Disorder Checklist (PCL-5) scores showed significant traumatic stress. …”
Get full text

General practitioners' perceptions of the burden of RSV and views on RSV immunisation – a qualitative interview study by Sarah F. Hak, Roderick P. Venekamp, Tamara Platteel, Louis J. Bont, Joanne G. Wildenbeest, Sibyl Anthierens

“…This drives a general assumption of low disease burden in older adults and low perceived need for RSV immunisation. GPs stress the need for targeted education on RSV epidemiology and immunisation options to better guide (parental) decision-making. …”
Get full text

Wind speed and soil properties drive the height-diameter allometric pattern of island plants by Chengfeng Yang, Renfu Liao, Shengzhuo Huang, Yikang Cheng, Shurong Zhou

Get full text

Evaluation of Caregiving Burden in Caregivers of Children with Chronic Disease by Murat Doğan, Utku Özer, Tuğçe Kalın, Yılmaz Seçilmiş, Mehmet Adnan Öztürk

“…In those with moderate to severe care burden, later disease development and economic difficulties were greater and education levels were lower (p<0.05).Conclusion:Care burdens should be reduced by providing more economic and social support to those who care for the child with chronic disease and by educating healthcare professionals on issues such as disease management, problem solving and coping with stress.…”
Get full text

Exploring dietary perception, beliefs and practices among pregnant adolescents, their husbands and healthcare providers in West Arsi, Central Ethiopia: a phenomenological study by Adane Tesfaye, Tefera Belachew, Dessalegn Tamiru, Yohanness Addisu Wondimagegne

“…Husbands’ involvement in nutrition education and specific nutrition training for healthcare providers are the other facilitators identified in this study. …”
Get full text

The effect of physical activity on resilience of Chinese children: the chain mediating effect of executive function and emotional regulation by Yifan Xu, Kai Qi, Shuqiao Meng, Xiaoxiao Dong, Shimeng Wang, Dandan Chen, Aiguo Chen

“…These findings not only enhance the understanding of the mechanisms underlying children’s resilience development but also offer new perspectives for designing interventions to promote children’s mental health. Future educational and public health policies should integrate PA with cognitive-emotional training to effectively enhance children’s ability to cope with stress and challenges.…”
Get full text

Exploring dementia care for community-dwelling older adults in Thailand: A qualitative descriptive study by Parichat Mongklam, Phachongchit Kraithaworn, Sangduen Piyatrakul

“…Strengthening caregiver education, expanding service networks, and enhancing integrated support systems are critical for improving care quality and reducing caregiver burden. …”
Get full text

Family Coping Strategies and Quality of Life of Patients with Type-2 Diabetes Mellitus in Primary Health Care in Indonesia by Setyoadi Setyoadi, Ferry Efendi, Joni Haryanto, Fitri Rosyidawati, Niko Dima Kristianingrum, Yati Srihayati, Dina Dewi Sartika Lestari Ismail

“…Background: The intricate caregiving responsibilities undertaken by family caregivers in the care of patients with chronic diseases induce stress, potentially reducing the family’s ability to provide effective care. …”
Get full text

Cutaneous leiomyoma of muscles lifting hair: description of a new clinical syndrome - myalgia in the rem sleep phase (clinical case) by I. A. Kuklin, M. M. Kokhan, V. A. Iglikov, I. D. Kuznetsov, M. K. Kuklina, E. V. Redkina

Get full text

Predictors of in-hospital Mortality After Rapid Response System Activation in a Newly Established Tertiary Hospital by Büşra Tezcan, Müçteba Can, Çilem Bayındır Dicle, İbrahim Mungan, Derya Ademoğlu

“…In this study, we evaluated the predictive factors of in-hospital mortality for patients who were subjects of RRS activation in a newly established major hospital in Turkey.Materials and Methods:Data on RRS activations were reviewed from paper charts and electronic medical records between March 2019 and February 2020. …”
Get full text

Is L‐Arginine an Appropriate Alternative for Conventional Anti‐Atherosclerotic Therapy?: A Comprehensive Review by Ali Mortezaei, Mohammad Ghorbani, Bardia Hajikarimloo, Omar Sameer, Toba Kazemi, Ebrahim Salavati, Mohsen Hamidpour, Mohammad Esmail Gheydari

“…Results L‐Arg supplementation has shown promising effects on NO production, improving endothelial function and reducing oxidative stress in preclinical models. Clinical studies have indicated moderate improvements in vascular health markers, including reductions in inflammation and oxidative stress, although results have varied across studies. …”
Get full text

Machine Learning for the Photonic Evaluation of Cranial and Extracranial Sites in Healthy Individuals and in Patients with Multiple Sclerosis by Antonio Currà, Riccardo Gasbarrone, Davide Gattabria, Nicola Luigi Bragazzi, Giuseppe Bonifazi, Silvia Serranti, Paolo Missori, Francesco Fattapposta, Carlotta Manfredi, Andrea Maffucci, Luca Puce, Lucio Marinelli, Carlo Trompetto

“…Classification models achieved perfect performance (accuracy = 1.00), and cortical site regression models showed strong predictive power (EDSS: R²_CV = 0.980; FSS: R²_CV = 0.939). …”
Get full text

Estimation of Longitudinal and Transverse Elastic Moduli of Native Brazilian Woods by Static Bending Tests by Fabricio da Silva Aguiar, Guilherme dos Santos Silva, Herisson Ferreira dos Santos, Elvys Dias Reis, Francisco Antonio Rocco Lahr, André Luis Christoforo

“…The results showed that, for L/h ratios below 18, the apparent modulus of elasticity was significantly affected by shear effects, exhibiting reductions of up to 18.47%. The E/G ratio ranged from 14.84 to 21.15, corresponding to a reduction of up to 7% and an increase of up to 32%, respectively, about the value proposed by ABNT NBR 7190-1 (2022). …”
Get full text

Metabolic modulation-driven self-reinforcing pyroptosis-STING nanoadjuvant for potentiated metalloimmunotherapy by Linzhu Zhang, Di Wang, Yiming Liu, Nailin Yang, Shumin Sun, Chunjie Wang, Duo Wang, Jihu Nie, Juan Qin, Lei Zhang, Liang Cheng, Haidong Zhu

Get full text

PO32 | Effect of the sodium-glucose co-transporter-2 (SGLT2) inhibitors on platelet activation and lipid peroxidation: results of a pilot study

“…Results: In patients treated with gliflozins, we observed significant reductions markers of platelet activation and oxidative stress: 11-dehydro-TXB2 (p=0.032) (Figure 1, panel A), 8-iso-prostaglandin (PG)F2α (p=0.026) (Figure 1, panel B). …”
Get full text

Nature-based virtual reality relaxation to improve mental health and sleep in undergraduate students: A randomized controlled trial by Junggeun Ahn, Jiu Kim, Youngeun Park, Riah Kim, Heeseung Choi

“…The VR intervention group showed significant reductions in perceived stress levels ( p  = .001) and improvements in subjective sleep patterns ( p  = .046), with these effects sustained at follow-up. …”
Get full text

Exploring ribosome biogenesis in lung adenocarcinoma to advance prognostic methods and immunotherapy strategies by Zipei Song, Yuheng Wang, Miaolin Zhu, Pengpeng Zhang, Zhihua Li, Xin Geng, Xincen Cao, Jianan Zheng, Jianwei Tang, Liang Chen

“…Compared to other prognostic models, RBS demonstrated superior performance in prognosis prediction. The low-RBS group exhibited a tumor microenvironment (TME) more favorable for efficient immune monitoring and reaction, higher responsiveness to immunotherapy, and a better prognosis. …”
Get full text

Interactions between gut microbiota, plasma metabolome and brain function in the setting of a HIV cure trial by Alessandra Borgognone, Anna Prats, Anna Prats, Ashish Arunkumar Sharma, Ignacio Martinez-Zalacaín, Ignacio Martinez-Zalacaín, Carles Soriano-Mas, Carles Soriano-Mas, Carles Soriano-Mas, Christian Brander, Christian Brander, Christian Brander, Christian Brander, Bonaventura Clotet, Bonaventura Clotet, Bonaventura Clotet, Bonaventura Clotet, Bonaventura Clotet, José Moltó, José Moltó, José Moltó, Beatriz Mothe, Beatriz Mothe, Beatriz Mothe, Beatriz Mothe, Beatriz Mothe, Rafick-Pierre Sekaly, Roger Paredes, Roger Paredes, Roger Paredes, Roger Paredes, Roger Paredes, Roger Paredes, Roger Paredes, Jose A. Muñoz-Moreno, Jose A. Muñoz-Moreno, Jose A. Muñoz-Moreno

“…Furthermore, the three indices and related discriminant features correlated negatively with functional outcomes, such as quality of life and daily functioning, and positively with depression, stress and CNS-related symptoms before RMD administration, while these associations became less discernible at the subsequent timepoints.ConclusionsWhile the direct effect of the intervention on the observed shifts cannot be conclusively determined in this study settings, these findings strengthen the link between gut bacteria, related metabolites, and neurocognitive function in PWH, and provide an analytical framework for future validation studies aimed at discovering predictive biomarkers for neurocognitive impairment in PWH.…”
Get full text

Awareness among Women about Epidural Analgesia in Riyadh, Saudi Arabia by Sarah W. Alnosaier, Asrar A. Alahmadi, Sarah W. Alnafe, Bandar S. Alshehry

“…This experience may cause physical and/or psychological stress before and during the birth process. Part of the stress a woman may experience relates to the pain endured during labor. …”
Get full text

Multi-omics investigation of metabolic dysregulation in depression: integrating metabolomics, weighted gene co-expression network analysis, and mendelian randomization by Wu Qianhao, Wu Qianhao, Zhang Jinwen, Zhang Jinwen, Miao Jingjie, Miao Jingjie, Chen Xiaoyu, Zhao Yangfei, Yao Wenxiu, Jiang Xu, Wang Xiaojun, Han Peipei, Guo Qi, Guo Qi

Get full text