IL-4 and IL-13 in Cardiovascular Disease: From Immune Modulation to Therapeutic Possibilities – A Narrative Review by Kılıç AT, Bora R, Toprak B

“…Ahmet Turhan Kılıç,1 Rıdvan Bora,2 Burak Toprak1 1Department of Cardiovascular Surgery, Mersin City Education and Research Hospital, Mersin, Turkey; 2Department of Cardiology, Tarsus State Hospital, Mersin, TurkeyCorrespondence: Burak Toprak, Department of Cardiovascular Surgery, Mersin City Education and Research Hospital, Kuzeykent District, 31131 Street No: 1, Floor: 6, Flat No: 11, Yenişehir, Mersin, 33120, Turkey, Email brk.tprk@gmail.comBackground: Interleukin-4 (IL-4) and Interleukin-13 (IL-13) are central regulators of the Th2 immune response and play pivotal roles in vascular inflammation, endothelial dysfunction, and cardiovascular remodeling. …”
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A microfluidic coculture model for mapping signaling perturbations and precise drug screening against macrophage-mediated dynamic myocardial injury by Zhao Gao, Zhiyong Du, Yu Hou, Kun Hua, Pengfei Tu, Xiaoni Ai, Yong Jiang

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Dual-targeted siRubicon delivery strategy triggers hepatocellular lipophagy for mitigating liver steatosis by Tingting Lan, Qiushi Li, Mingxing Yu, Xu Duan, Tao Ming, Shuo Li, Chunjiong Wang, Yi Zhu, Zhongyang Shen, Deling Kong, Yang Liu

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Parents’ State and Trait Anxiety Levels During Bloodletting Attempts in the Pediatric Emergency Department by Ahmet Butun, Sema Bayraktar, Meltem Çatalbaş

“…Introduction: Parental stress and anxiety during pediatric bloodletting in the pediatric emergency department (PED) are influenced by a complex interplay of factors, including the child’s medical condition, unfamiliarity with procedures, healthcare-provider interactions, and parental knowledge gaps. …”
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Research on the evolution mechanism of shale mechanical properties under variable bedding angles by Feng Du, Feng Du, Feng Du, Bing Liang, Xiaoyong Wen, Xiaoyong Wen, Qian Liu, Qian Liu, Junxiu Ma, Yixing Ren, Mi Zhang, Jihan Liu, Jin Tan

“…This leads to incorrect prediction of fracturing parameters, which results in inefficient fracturing reconstruction of shale reservoir. …”
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Changes in Preterm and Low Birthweight Birth Rate During the COVID-19 Lockdown at Two San Francisco Hospitals by Anoushka Kathiravan, Zoe R. Schauer, Janet M. Wojcicki

“…Abstract Objective The COVID-19 lockdown impacted interactions with the health care system and societal stress levels. Previous US-based studies suggest that pandemic lockdowns may have lowered preterm birth rates although there are mixed findings from different settings. …”
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Estrés y su afrontamiento en directores y directoras de colegios y escuelas en el circuito 03 de la provincia de Heredia by Pedro Ureña-Bonilla, Carmen Castro-Sancho

“…The purpose of this study was to analyze how school principals working in the third circuit of the province of Heredia experienced and faced stress. 17 educational managers (11 women and 6 men) participated in the survey. …”
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Genome-wide identification of SWEET gene family and functional analysis of BcSWEET1-2 associated with flowering in flowering Chinese cabbage (Brassica campestris) by Xinmin Huang, Liming He, Yuyao Chen, Yin Liu, Jinfeng Liu, Guangyuan Lu, Riyuan Chen, Yunna Zhu, Shiwei Song, Qinqin He

“…However, all BcSWEET proteins are predicted to be localized in the cell membrane. Prediction of transmembrane regions showed that all members contained the MtN3/saliva domain. …”
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Relationship of the oxidative balance score with the risk of frailty and mortality in patients with asthma: a mediation analysis of NHANES by Minghao Liang, Hongling Jia, Lili Sun, Wenjing Xi, Feilong Guan, Di Huang, Yifei Xu, Guangfeng Chen, Xianhai Chen, Minyan Jin, Zhanjun Qiu

“…After adjustment for covariates, each one-unit increase in the OBS was associated with a 4% reduction in the risk of frailty (OR: 0.96, 95% CI: 0.94–0.99) and a 5% reduction in the risk of mortality (HR: 0.95, 95% CI: 0.93–0.97). …”
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A Chimeric Peptide Derived from a Bacterial Effector Protein Attenuates TLR-2/4-Mediated Production of Pro-Inflammatory Cytokines and Enhances the Cellular Availability of Gentamic... by Nandi BR, Patra B, Radhakrishnan GK

“…Additionally, TcpB-derived peptides conjugated to gentamicin were analyzed for enhanced intracellular delivery, bacterial clearance, and anti-inflammatory effects using CFU enumeration, ELISA, and qRT-PCR in both in vitro and in vivo.Results: TB4-BBL2 peptide was efficiently internalized by macrophages via endocytosis and promoted the degradation of TIRAP and MYD88, thereby attenuating TLR2/4-mediated pro-inflammatory cytokine production and oxidative stress. In vivo, TB4-BBL2 treatment resulted in over a 70% reduction in serum TNF-α levels, which was also reflected by decreased transcript levels in spleen tissue. …”
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Non-thermal processing techniques for sustainable food supply chains by Kaiser Younis, Kausar Jahan, Ovais Shafiq Qadri, Khwaja Osama, Owais Yousuf

“…The societal inferences, safety attention, regulatory issues, and consumer acceptance of these technologies are also discussed, highlighting the health rewards and the necessity for increased awareness and education. The review stresses nonthermal processing's pivotal role in promoting sustainable food systems by mitigating food waste, conserving resources, and lowering carbon emissions. …”
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Altered Biomechanical Properties of Gastrocnemius Tendons of Turkeys Infected with Turkey Arthritis Reovirus by Tamer A. Sharafeldin, Qingshan Chen, Sunil K. Mor, Sagar M. Goyal, Robert E. Porter

“…We propose that tendon fibrosis is one of the key features contributing to reduction in tensile strength and elasticity of gastrocnemius tendons in TARV-infected turkeys.…”
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A robust data-driven approach for modeling turbulent transport by R. Varennes, Z.S. Qu, Y.W. Cho, C. Wan, K. Li, R.A. Heinonen, V. Grandgirard

“…E 101 061201) proposed a data-driven approach using neural networks to predict the particle flux and Reynolds stress in a minimal model of drift-wave turbulence. …”
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Conjugation effects on antibiotic resistance genes at various salt Levels: Insights from single-factor and simulation study by Pei Jiang, Yu Xia, Jiali Chang, Cheng Zhang, Xia Li, Le Fang, Xinhui Liu

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Cocultured amniotic stem cells and cardiomyocytes in a 3-D acellular heart patch reduce the infarct size and left ventricle remodeling: promote angiogenesis in a porcine acute myoc... by Muhammad Arza Putra, Normalina Sandora, Tri Wisesa Soetisna, Tyas Rahmah Kusuma, Nur Amalina Fitria, Benati Karimah, Deni Noviana, Gunanti, Pribadi Wiranda Busro, Supomo, Idrus Alwi

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Factor analysis, emotional experience and behavioral feedback of contemporary Chinese youth participating in short-term monasticism: a qualitative study based on the online questio... by Chao Liu, Chao Liu, Li-Jen Lin, Li-Jen Lin, Hao Chen, Hao Chen, Thu-Hua Liu, Thu-Hua Liu, Huang-Li Lin, Wen-Ko Chiou, Wen-Ko Chiou, Wen-Ko Chiou, Wen-Ko Chiou

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The role of social relationships in recovery court programs by Emma Katherine Dudley, Barbara Andraka-Christou, Alexandra Boland, Danielle N. Atkins, Ekaterina Pivovarova

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Psychological distress and COVID-19 vaccine hesitancy among parents of in-school children after the end of the zero-COVID-19 policy: A city-wide survey in South China by Ruiyin Zhang, Fangmei Ren, Yucheng Xu, Jingjie Fan, Wei Lin

“…Parents with anxiety (OR: 1.685, 95%CI: 1.250 ~ 2.272), depression (OR: 1.507, 95%CI: 1.105 ~ 2.054), and a high-stress level (OR: 1.162, 95%CI: 1.000 ~ 1.350) were more likely to report vaccine hesitancy. …”
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Research of physicomechanical and design characteristics of vibrated, centrifuged and vibro-centrifuged concretes by L. R. Mailyan, S. A. Stel'makh, E. M. Shcherban, Yu. V. Zherebtsov, M. M. Al-Tulaikhi

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The impact of self-efficacy on substance use in nursing students: the mediating role of sense of coherence by Daria Schneider-Matyka, Anna Maria Cybulska, Mariusz Panczyk, Anna Andruszkiewicz, Danuta Dyk, Aleksandra Gaworska-Krzemińska, Agnieszka Gniadek, Dorota Kozieł, Ewa Kupcewicz, Agnieszka Młynarska, Jolanta Lewko, Barbara Ślusarska, Magdalena Śniegocka, Elżbieta Grochans, Kamila Rachubińska

“…Strengthening SOC through targeted interventions may help mitigate risky behaviors and improve overall well-being. Educational programs focusing on resilience, stress management, and coherence-building strategies could be beneficial for nursing students to support their future professional roles. …”
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